More than 300 homologs were found in PanDaTox collection
for query gene BbuZS7_0421 on replicon NC_011728
Organism: Borrelia burgdorferi ZS7



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011728  BbuZS7_0421  response regulatory protein  100 
 
 
305 aa  617  1e-176  Borrelia burgdorferi ZS7  Bacteria  normal  0.972098  n/a   
 
 
-
 
NC_008576  Mmc1_3528  response regulator receiver modulated diguanylate cyclase  41.12 
 
 
310 aa  243  3.9999999999999997e-63  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_008789  Hhal_0365  response regulator receiver modulated diguanylate cyclase  41.16 
 
 
308 aa  240  2e-62  Halorhodospira halophila SL1  Bacteria  normal  n/a   
 
 
-
 
NC_007954  Sden_1684  GGDEF domain-containing protein  41.02 
 
 
323 aa  238  1e-61  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_29300  Response regulator  39.07 
 
 
310 aa  236  3e-61  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_2955  response regulator receiver modulated diguanylate cyclase  41.24 
 
 
308 aa  234  1.0000000000000001e-60  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_1341  response regulator receiver modulated diguanylate cyclase  39.31 
 
 
319 aa  234  2.0000000000000002e-60  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_4132  response regulator receiver modulated diguanylate cyclase  41.55 
 
 
310 aa  232  6e-60  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_009665  Shew185_4204  response regulator receiver modulated diguanylate cyclase  41.55 
 
 
310 aa  232  6e-60  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_4336  response regulator receiver modulated diguanylate cyclase  40.68 
 
 
310 aa  231  9e-60  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_013173  Dbac_2032  response regulator receiver modulated diguanylate cyclase  42.38 
 
 
310 aa  229  4e-59  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_010524  Lcho_3544  response regulator receiver modulated diguanylate cyclase  39.38 
 
 
322 aa  228  9e-59  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0106122 
 
 
-
 
NC_010002  Daci_1192  response regulator receiver modulated diguanylate cyclase  37.41 
 
 
316 aa  228  9e-59  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_4015  response regulator receiver modulated diguanylate cyclase  41.22 
 
 
315 aa  228  1e-58  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_012880  Dd703_3123  response regulator receiver modulated diguanylate cyclase  39.38 
 
 
312 aa  228  1e-58  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_008228  Patl_4177  diguanylate cyclase  38.41 
 
 
347 aa  224  1e-57  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_010506  Swoo_0828  response regulator receiver modulated diguanylate cyclase  40.82 
 
 
324 aa  224  1e-57  Shewanella woodyi ATCC 51908  Bacteria  normal  normal 
 
 
-
 
NC_007575  Suden_0218  diguanylate cyclase  44.52 
 
 
304 aa  223  4.9999999999999996e-57  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_2812  diguanylate cyclase  40.21 
 
 
315 aa  222  6e-57  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_008228  Patl_3669  diguanylate cyclase  38.64 
 
 
300 aa  219  3.9999999999999997e-56  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.0119902  n/a   
 
 
-
 
NC_007005  Psyr_2939  GGDEF  40.2 
 
 
318 aa  214  9.999999999999999e-55  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.417006  normal 
 
 
-
 
NC_011884  Cyan7425_3210  response regulator receiver modulated diguanylate cyclase  36.7 
 
 
337 aa  212  5.999999999999999e-54  Cyanothece sp. PCC 7425  Bacteria  normal  0.32327  normal  0.712325 
 
 
-
 
NC_011729  PCC7424_0984  response regulator receiver modulated diguanylate cyclase  37.05 
 
 
353 aa  211  9e-54  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.194443 
 
 
-
 
NC_011146  Gbem_1228  response regulator receiver modulated diguanylate cyclase  38.19 
 
 
349 aa  209  5e-53  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_1561  response regulator receiver modulated diguanylate cyclase  41.55 
 
 
455 aa  208  9e-53  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.0000000734361  n/a   
 
 
-
 
NC_008228  Patl_2089  diguanylate cyclase  37.67 
 
 
306 aa  204  1e-51  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1006  response regulator receiver modulated diguanylate cyclase  38.08 
 
 
312 aa  204  2e-51  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_009831  Ssed_1382  response regulator receiver protein  37.37 
 
 
302 aa  202  4e-51  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_0748  response regulator receiver protein  36.39 
 
 
312 aa  200  3e-50  Shewanella amazonensis SB2B  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_0065  response regulator receiver protein  37.88 
 
 
305 aa  200  3e-50  Shewanella amazonensis SB2B  Bacteria  normal  normal 
 
 
-
 
NC_014248  Aazo_5066  response regulator receiver modulated diguanylate cyclase  37.42 
 
 
338 aa  199  3.9999999999999996e-50  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_009654  Mmwyl1_1645  response regulator receiver modulated diguanylate cyclase  34.68 
 
 
308 aa  199  7e-50  Marinomonas sp. MWYL1  Bacteria  normal  normal  0.456967 
 
 
-
 
NC_011726  PCC8801_1139  response regulator receiver modulated diguanylate cyclase  36.39 
 
 
308 aa  194  2e-48  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_1169  response regulator receiver modulated diguanylate cyclase  36.39 
 
 
308 aa  194  2e-48  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_0178  response regulator receiver modulated diguanylate cyclase  37.95 
 
 
322 aa  190  2e-47  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.895619 
 
 
-
 
NC_009654  Mmwyl1_0135  response regulator receiver modulated diguanylate cyclase  36.86 
 
 
306 aa  189  7e-47  Marinomonas sp. MWYL1  Bacteria  normal  normal  0.248217 
 
 
-
 
NC_013216  Dtox_1577  response regulator receiver modulated diguanylate cyclase  36.25 
 
 
314 aa  188  8e-47  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_011138  MADE_02505  putative response regulator  35.37 
 
 
306 aa  188  9e-47  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_014248  Aazo_1477  response regulator receiver modulated diguanylate cyclase  36.33 
 
 
317 aa  188  1e-46  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_1030  response regulator receiver modulated diguanylate cyclase  33.78 
 
 
330 aa  187  2e-46  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.33399 
 
 
-
 
NC_009092  Shew_3790  response regulator receiver modulated diguanylate cyclase  35.05 
 
 
300 aa  187  2e-46  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_1507  response regulator receiver modulated diguanylate cyclase  34.34 
 
 
308 aa  186  4e-46  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.914031 
 
 
-
 
NC_011313  VSAL_II0052  response regulator protein  37.8 
 
 
299 aa  186  6e-46  Aliivibrio salmonicida LFI1238  Bacteria  normal  0.189873  n/a   
 
 
-
 
NC_013161  Cyan8802_2067  response regulator receiver modulated diguanylate cyclase  36.36 
 
 
317 aa  184  1.0000000000000001e-45  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_2041  response regulator receiver modulated diguanylate cyclase  36.36 
 
 
317 aa  184  1.0000000000000001e-45  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013422  Hneap_0133  response regulator receiver modulated diguanylate cyclase  34.68 
 
 
461 aa  184  1.0000000000000001e-45  Halothiobacillus neapolitanus c2  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_2383  response regulator receiver modulated diguanylate cyclase  35.45 
 
 
434 aa  183  2.0000000000000003e-45  Saccharophagus degradans 2-40  Bacteria  normal  hitchhiker  0.00665942 
 
 
-
 
NC_007484  Noc_0847  two component diguanylate cyclase  35.42 
 
 
327 aa  183  3e-45  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_010506  Swoo_1513  response regulator receiver modulated diguanylate cyclase  35.84 
 
 
301 aa  181  9.000000000000001e-45  Shewanella woodyi ATCC 51908  Bacteria  normal  normal  0.0153071 
 
 
-
 
NC_013173  Dbac_0019  response regulator receiver modulated diguanylate cyclase  33.33 
 
 
341 aa  181  1e-44  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.0416556  n/a   
 
 
-
 
NC_009831  Ssed_1645  hypothetical protein  34.76 
 
 
344 aa  171  1e-41  Shewanella sediminis HAW-EB3  Bacteria  normal  0.176846  normal 
 
 
-
 
NC_007760  Adeh_3473  response regulator receiver modulated diguanylate cyclase  33.98 
 
 
351 aa  167  2e-40  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_3005  response regulator receiver modulated diguanylate cyclase  34.01 
 
 
303 aa  167  2.9999999999999998e-40  Saccharophagus degradans 2-40  Bacteria  normal  hitchhiker  0.000288968 
 
 
-
 
NC_011145  AnaeK_3557  response regulator receiver modulated diguanylate cyclase  34.55 
 
 
322 aa  166  5e-40  Anaeromyxobacter sp. K  Bacteria  normal  0.457648  n/a   
 
 
-
 
NC_011891  A2cp1_3625  response regulator receiver modulated diguanylate cyclase  33.88 
 
 
322 aa  165  8e-40  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_00724  putative response regulator  31.16 
 
 
329 aa  162  5.0000000000000005e-39  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_1597  response regulator receiver modulated diguanylate cyclase  34.42 
 
 
313 aa  162  9e-39  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_1665  response regulator receiver modulated diguanylate cyclase  31.27 
 
 
313 aa  161  1e-38  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_010718  Nther_1974  response regulator receiver modulated diguanylate cyclase  34.84 
 
 
340 aa  161  2e-38  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.098619 
 
 
-
 
NC_011891  A2cp1_2397  response regulator receiver modulated diguanylate cyclase  31.97 
 
 
434 aa  159  5e-38  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.593336  n/a   
 
 
-
 
NC_011145  AnaeK_2309  response regulator receiver modulated diguanylate cyclase  31.97 
 
 
434 aa  159  6e-38  Anaeromyxobacter sp. K  Bacteria  normal  0.484645  n/a   
 
 
-
 
NC_007912  Sde_2463  response regulator receiver modulated diguanylate cyclase  34.56 
 
 
301 aa  155  1e-36  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_0195  response regulator receiver modulated diguanylate cyclase  32.14 
 
 
309 aa  154  2e-36  Geobacter uraniireducens Rf4  Bacteria  normal  0.0106599  n/a   
 
 
-
 
NC_008709  Ping_0978  response regulator receiver modulated diguanylate cyclase  40.18 
 
 
322 aa  153  2.9999999999999998e-36  Psychromonas ingrahamii 37  Bacteria  normal  0.97362  decreased coverage  0.00116316 
 
 
-
 
NC_013161  Cyan8802_0849  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  33.33 
 
 
593 aa  153  4e-36  Cyanothece sp. PCC 8802  Bacteria  normal  0.386146  normal 
 
 
-
 
NC_011726  PCC8801_0820  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  33.33 
 
 
593 aa  153  4e-36  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013216  Dtox_3787  response regulator receiver modulated diguanylate cyclase  30.12 
 
 
344 aa  152  5e-36  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.919533  normal  0.90313 
 
 
-
 
NC_010814  Glov_3614  response regulator receiver modulated diguanylate cyclase  32.45 
 
 
310 aa  152  8.999999999999999e-36  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_1556  response regulator receiver modulated diguanylate cyclase  31.25 
 
 
300 aa  150  3e-35  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_1554  response regulator receiver modulated diguanylate cyclase  33.1 
 
 
419 aa  149  5e-35  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_0963  response regulator receiver modulated diguanylate cyclase  31.67 
 
 
300 aa  149  6e-35  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU3376  GGDEF/response regulator receiver domain-containing protein  32.01 
 
 
308 aa  148  1.0000000000000001e-34  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_1332  response regulator receiver modulated diguanylate cyclase  32.68 
 
 
306 aa  147  2.0000000000000003e-34  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_2951  response regulator receiver modulated diguanylate cyclase  31.1 
 
 
306 aa  147  2.0000000000000003e-34  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007974  Rmet_3967  putative response regulator of a two-component system  31.9 
 
 
335 aa  147  2.0000000000000003e-34  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.000645274  normal  0.0110626 
 
 
-
 
NC_009784  VIBHAR_05729  putative diguanylate cyclase  31.39 
 
 
323 aa  147  2.0000000000000003e-34  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_010322  PputGB1_1099  response regulator receiver modulated diguanylate cyclase  31.9 
 
 
334 aa  146  4.0000000000000006e-34  Pseudomonas putida GB-1  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_3851  response regulator receiver modulated diguanylate cyclase  28.35 
 
 
634 aa  146  5e-34  Thauera sp. MZ1T  Bacteria  normal  0.0571122  n/a   
 
 
-
 
NC_009512  Pput_4228  response regulator receiver modulated diguanylate cyclase  31.9 
 
 
334 aa  145  6e-34  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_5250  response regulator receiver modulated diguanylate cyclase  30.84 
 
 
360 aa  145  6e-34  Delftia acidovorans SPH-1  Bacteria  normal  0.395511  normal  0.949965 
 
 
-
 
NC_007298  Daro_0709  response regulator receiver modulated diguanylate cyclase  29.22 
 
 
322 aa  145  8.000000000000001e-34  Dechloromonas aromatica RCB  Bacteria  normal  normal  0.169559 
 
 
-
 
NC_008228  Patl_0265  diguanylate cyclase  30.54 
 
 
310 aa  145  9e-34  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.021653  n/a   
 
 
-
 
NC_007492  Pfl01_1058  response regulator receiver modulated diguanylate cyclase  32.26 
 
 
333 aa  144  1e-33  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.0856452  normal  0.699737 
 
 
-
 
NC_013457  VEA_000121  response regulator  32.9 
 
 
319 aa  145  1e-33  Vibrio sp. Ex25  Bacteria  normal  0.0601608  n/a   
 
 
-
 
NC_007348  Reut_B3647  response regulator receiver modulated diguanylate cyclase  31.18 
 
 
359 aa  144  2e-33  Ralstonia eutropha JMP134  Bacteria  normal  0.745021  n/a   
 
 
-
 
NC_002947  PP_1494  response regulator/GGDEF domain-containing protein  31.54 
 
 
335 aa  143  3e-33  Pseudomonas putida KT2440  Bacteria  normal  normal  0.799611 
 
 
-
 
NC_007413  Ava_3170  response regulator receiver modulated diguanylate cyclase  28.17 
 
 
344 aa  143  4e-33  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.103544 
 
 
-
 
NC_007517  Gmet_0069  response regulator receiver modulated diguanylate cyclase  30.29 
 
 
314 aa  143  4e-33  Geobacter metallireducens GS-15  Bacteria  normal  normal  0.840661 
 
 
-
 
NC_007511  Bcep18194_B2018  response regulator receiver modulated diguanylate cyclase  30.82 
 
 
355 aa  142  5e-33  Burkholderia sp. 383  Bacteria  normal  0.414914  normal  0.602726 
 
 
-
 
NC_007604  Synpcc7942_2534  diguanylate cyclase with GAF sensor  43.43 
 
 
421 aa  142  5e-33  Synechococcus elongatus PCC 7942  Bacteria  normal  0.657544  normal 
 
 
-
 
NC_010501  PputW619_4124  response regulator receiver modulated diguanylate cyclase  32.01 
 
 
334 aa  142  9e-33  Pseudomonas putida W619  Bacteria  normal  0.113929  normal 
 
 
-
 
NC_007614  Nmul_A2693  diguanylate cyclase  30.38 
 
 
302 aa  141  9.999999999999999e-33  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_0667  response regulator receiver domain-containing protein  31.73 
 
 
1526 aa  141  9.999999999999999e-33  Saccharophagus degradans 2-40  Bacteria  normal  0.0280955  hitchhiker  0.000000898802 
 
 
-
 
NC_013526  Tter_2192  response regulator receiver modulated diguanylate cyclase  30.54 
 
 
303 aa  141  1.9999999999999998e-32  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_16500  two-component response regulator  30 
 
 
347 aa  140  1.9999999999999998e-32  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.67066  normal 
 
 
-
 
NC_007005  Psyr_1309  GGDEF  31.9 
 
 
334 aa  140  3e-32  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  hitchhiker  0.00365402 
 
 
-
 
NC_008312  Tery_4231  response regulator receiver modulated diguanylate cyclase  31.65 
 
 
357 aa  140  3e-32  Trichodesmium erythraeum IMS101  Bacteria  normal  0.113145  normal  0.678212 
 
 
-
 
NC_010623  Bphy_5389  response regulator receiver modulated diguanylate cyclase  29.75 
 
 
372 aa  140  3.9999999999999997e-32  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_3688  response regulator receiver modulated diguanylate cyclase  33.9 
 
 
543 aa  139  4.999999999999999e-32  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_009675  Anae109_3583  response regulator receiver modulated diguanylate cyclase  31.91 
 
 
322 aa  139  6e-32  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  hitchhiker  0.000864033 
 
 
-
 
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