More than 300 homologs were found in PanDaTox collection
for query gene Msil_3785 on replicon NC_011666
Organism: Methylocella silvestris BL2



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_011666  Msil_3785  Methylmalonyl-CoA mutase  100 
 
 		 621 aa  1220    Methylocella silvestris BL2  Bacteria  n/a    normal  0.546238 
 
 
-
 
NC_011894  Mnod_5425  methylmalonyl-CoA mutase  46.92 
 
 		 612 aa  417  9.999999999999999e-116  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.559772  n/a   
 
 
-
 
NC_007964  Nham_2636  methylmalonyl-CoA mutase  44.59 
 
 		 629 aa  416  9.999999999999999e-116  Nitrobacter hamburgensis X14  Bacteria  normal  0.668897  n/a   
 
 
-
 
NC_007958  RPD_1929  methylmalonyl-CoA mutase  43.27 
 
 		 623 aa  413  1e-114  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.102484  normal  1 
 
 
-
 
NC_011004  Rpal_2041  Methylmalonyl-CoA mutase  45.11 
 
 		 623 aa  412  1e-114  Rhodopseudomonas palustris TIE-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_007406  Nwi_2236  methylmalonyl-CoA mutase  44.36 
 
 		 639 aa  409  1.0000000000000001e-112  Nitrobacter winogradskyi Nb-255  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010511  M446_0217  methylmalonyl-CoA mutase  48.12 
 
 		 611 aa  401  9.999999999999999e-111  Methylobacterium sp. 4-46  Bacteria  normal  1  normal  0.0670454 
 
 
-
 
NC_007778  RPB_3536  methylmalonyl-CoA mutase  43.34 
 
 		 623 aa  392  1e-108  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0287465  normal  0.381464 
 
 
-
 
NC_007925  RPC_1762  methylmalonyl-CoA mutase  44.04 
 
 		 621 aa  390  1e-107  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  0.223035 
 
 
-
 
NC_009485  BBta_3023  methylmalonyl-CoA mutase small subunit (MCM-beta)  43.83 
 
 		 621 aa  385  1e-106  Bradyrhizobium sp. BTAi1  Bacteria  normal  1  normal  0.577425 
 
 
-
 
NC_010505  Mrad2831_3135  methylmalonyl-CoA mutase  44.58 
 
 		 629 aa  387  1e-106  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.227192  normal  1 
 
 
-
 
NC_011757  Mchl_2665  Methylmalonyl-CoA mutase  44.74 
 
 		 605 aa  383  1e-105  Methylobacterium chloromethanicum CM4  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010172  Mext_2388  methylmalonyl-CoA mutase  44.91 
 
 		 605 aa  382  1e-104  Methylobacterium extorquens PA1  Bacteria  normal  0.55342  normal  1 
 
 
-
 
NC_010725  Mpop_2345  Methylmalonyl-CoA mutase  44.91 
 
 		 605 aa  372  1e-101  Methylobacterium populi BJ001  Bacteria  normal  0.418628  normal  1 
 
 
-
 
NC_010581  Bind_2200  methylmalonyl-CoA mutase  40.62 
 
 		 624 aa  337  3.9999999999999995e-91  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  1  normal  0.53913 
 
 
-
 
NC_009720  Xaut_4729  methylmalonyl-CoA mutase  44.74 
 
 		 610 aa  323  8e-87  Xanthobacter autotrophicus Py2  Bacteria  normal  1  normal  0.376161 
 
 
-
 
NC_007643  Rru_A2480  methylmalonyl-CoA mutase  37.37 
 
 		 698 aa  306  6e-82  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  1  n/a   
 
 
-
 
NC_013510  Tcur_2506  Methylmalonyl-CoA mutase  38.93 
 
 		 614 aa  293  6e-78  Thermomonospora curvata DSM 43183  Bacteria  decreased coverage  0.0000082079  n/a   
 
 
-
 
NC_007333  Tfu_2761  methylmalonyl-CoA mutase  37.54 
 
 		 630 aa  286  9e-76  Thermobifida fusca YX  Bacteria  normal  0.257221  n/a   
 
 
-
 
NC_008254  Meso_0857  methylmalonyl-CoA mutase  40.44 
 
 		 479 aa  282  1e-74  Chelativorans sp. BNC1  Bacteria  normal  0.315986  n/a   
 
 
-
 
NC_013159  Svir_05670  methylmalonyl-CoA mutase, N-terminal domain/subunit  39.1 
 
 		 622 aa  257  5e-67  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013093  Amir_6419  Methylmalonyl-CoA mutase  39.13 
 
 		 593 aa  253  1e-65  Actinosynnema mirum DSM 43827  Bacteria  normal  1  n/a   
 
 
-
 
NC_007777  Francci3_3006  methylmalonyl-CoA mutase  37.35 
 
 		 660 aa  249  1e-64  Frankia sp. CcI3  Bacteria  normal  0.84067  normal  0.316965 
 
 
-
 
NC_014211  Ndas_5544  Methylmalonyl-CoA mutase  36.39 
 
 		 644 aa  246  6.999999999999999e-64  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.11647  normal  1 
 
 
-
 
NC_009921  Franean1_1943  methylmalonyl-CoA mutase  37.63 
 
 		 653 aa  245  9.999999999999999e-64  Frankia sp. EAN1pec  Bacteria  normal  1  normal  0.133903 
 
 
-
 
NC_014165  Tbis_1921  methylmalonyl-CoA mutase  38.24 
 
 		 601 aa  239  1e-61  Thermobispora bispora DSM 43833  Bacteria  decreased coverage  0.00796016  normal  0.671948 
 
 
-
 
NC_010655  Amuc_1984  Methylmalonyl-CoA mutase  30.37 
 
 		 684 aa  238  3e-61  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  0.611894  normal  0.0597183 
 
 
-
 
NC_013757  Gobs_4374  Methylmalonyl-CoA mutase  36.33 
 
 		 640 aa  236  1.0000000000000001e-60  Geodermatophilus obscurus DSM 43160  Bacteria  normal  1  n/a   
 
 
-
 
NC_013595  Sros_3187  Methylmalonyl-CoA mutase  40.32 
 
 		 633 aa  222  1.9999999999999999e-56  Streptosporangium roseum DSM 43021  Bacteria  normal  0.800977  normal  0.217414 
 
 
-
 
NC_010338  Caul_3629  methylmalonyl-CoA mutase  38.02 
 
 		 489 aa  198  2.0000000000000003e-49  Caulobacter sp. K31  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009077  Mjls_3134  methylmalonyl-CoA mutase, beta subunit  34.32 
 
 		 615 aa  198  3e-49  Mycobacterium sp. JLS  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008146  Mmcs_3123  methylmalonyl-CoA mutase, small subunit  34.32 
 
 		 615 aa  197  4.0000000000000005e-49  Mycobacterium sp. MCS  Bacteria  normal  0.987709  n/a   
 
 
-
 
NC_012793  GWCH70_2295  methylmalonyl-CoA mutase, large subunit  26.32 
 
 		 681 aa  197  4.0000000000000005e-49  Geobacillus sp. WCH70  Bacteria  normal  1  n/a   
 
 
-
 
NC_008705  Mkms_3184  methylmalonyl-CoA mutase, beta subunit  34.32 
 
 		 615 aa  197  4.0000000000000005e-49  Mycobacterium sp. KMS  Bacteria  normal  1  normal  0.170851 
 
 
-
 
NC_009338  Mflv_3650  methylmalonyl-CoA mutase, beta subunit  37.15 
 
 		 620 aa  195  2e-48  Mycobacterium gilvum PYR-GCK  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013411  GYMC61_0278  methylmalonyl-CoA mutase, large subunit  29.66 
 
 		 682 aa  188  3e-46  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_008726  Mvan_2762  methylmalonyl-CoA mutase, beta subunit  34.49 
 
 		 626 aa  186  1.0000000000000001e-45  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.0864334  normal  1 
 
 
-
 
NC_011831  Cagg_1348  methylmalonyl-CoA mutase, large subunit  27.83 
 
 		 713 aa  185  2.0000000000000003e-45  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.000457861  unclonable  0.00000004793 
 
 
-
 
NC_009767  Rcas_3871  methylmalonyl-CoA mutase, large subunit  28.26 
 
 		 720 aa  184  5.0000000000000004e-45  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.949138  normal  0.194963 
 
 
-
 
NC_009523  RoseRS_0544  methylmalonyl-CoA mutase, large subunit  31.12 
 
 		 723 aa  182  2e-44  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009565  TBFG_11522  methylmalonyl-CoA mutase small subunit mutA  35.25 
 
 		 623 aa  179  2e-43  Mycobacterium tuberculosis F11  Bacteria  normal  1  normal  0.384078 
 
 
-
 
NC_013441  Gbro_2419  Methylmalonyl-CoA mutase  32.76 
 
 		 652 aa  176  9.999999999999999e-43  Gordonia bronchialis DSM 43247  Bacteria  normal  0.751014  n/a   
 
 
-
 
NC_014158  Tpau_2104  Methylmalonyl-CoA mutase  30.64 
 
 		 597 aa  172  2e-41  Tsukamurella paurometabola DSM 20162  Bacteria  normal  1  n/a   
 
 
-
 
NC_013169  Ksed_22180  methylmalonyl-CoA mutase, N-terminal domain/subunit  33.4 
 
 		 710 aa  169  2e-40  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.0921601  normal  0.211635 
 
 
-
 
NC_002950  PG1656  methylmalonyl-CoA mutase, small subunit  28.84 
 
 		 618 aa  159  2e-37  Porphyromonas gingivalis W83  Bacteria  n/a    normal  0.50388 
 
 
-
 
NC_010571  Oter_3305  methylmalonyl-CoA mutase, large subunit  29.82 
 
 		 706 aa  158  3e-37  Opitutus terrae PB90-1  Bacteria  normal  0.457427  normal  1 
 
 
-
 
NC_008347  Mmar10_1120  methylmalonyl-CoA mutase  37.26 
 
 		 480 aa  156  1e-36  Maricaulis maris MCS10  Bacteria  normal  1  normal  0.170859 
 
 
-
 
NC_013235  Namu_5167  Methylmalonyl-CoA mutase  37.74 
 
 		 600 aa  150  7e-35  Nakamurella multipartita DSM 44233  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008687  Pden_3681  methylmalonyl-CoA mutase  28.42 
 
 		 714 aa  145  2e-33  Paracoccus denitrificans PD1222  Bacteria  normal  0.542374  normal  1 
 
 
-
 
NC_010803  Clim_0869  Methylmalonyl-CoA mutase  28.43 
 
 		 604 aa  143  9.999999999999999e-33  Chlorobium limicola DSM 245  Bacteria  normal  1  n/a   
 
 
-
 
NC_007802  Jann_3367  methylmalonyl-CoA mutase  28.47 
 
 		 709 aa  142  9.999999999999999e-33  Jannaschia sp. CCS1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008048  Sala_1221  methylmalonyl-CoA mutase  28.6 
 
 		 715 aa  143  9.999999999999999e-33  Sphingopyxis alaskensis RB2256  Bacteria  normal  0.584735  normal  1 
 
 
-
 
NC_004310  BR1190  methylmalonyl-CoA mutase  29.62 
 
 		 712 aa  141  3e-32  Brucella suis 1330  Bacteria  normal  0.942727  n/a   
 
 
-
 
NC_009952  Dshi_0726  methylmalonyl-CoA mutase  28.15 
 
 		 712 aa  141  3.9999999999999997e-32  Dinoroseobacter shibae DFL 12  Bacteria  normal  0.999011  normal  1 
 
 
-
 
NC_011060  Ppha_1168  Methylmalonyl-CoA mutase  28.1 
 
 		 591 aa  141  3.9999999999999997e-32  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  0.648096  n/a   
 
 
-
 
NC_007794  Saro_0811  methylmalonyl-CoA mutase  28.27 
 
 		 714 aa  141  4.999999999999999e-32  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.251875  n/a   
 
 
-
 
NC_008044  TM1040_1865  methylmalonyl-CoA mutase  28.89 
 
 		 661 aa  139  1e-31  Ruegeria sp. TM1040  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008639  Cpha266_1165  methylmalonyl-CoA mutase  29.44 
 
 		 589 aa  139  2e-31  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  1  n/a   
 
 
-
 
NC_007493  RSP_2192  methylmalonyl-CoA mutase  28.9 
 
 		 709 aa  138  3.0000000000000003e-31  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.172259  n/a   
 
 
-
 
NC_009511  Swit_2891  methylmalonyl-CoA mutase  28.67 
 
 		 716 aa  137  5e-31  Sphingomonas wittichii RW1  Bacteria  normal  1  normal  0.17991 
 
 
-
 
NC_009049  Rsph17029_0867  methylmalonyl-CoA mutase  28.9 
 
 		 709 aa  137  5e-31  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  0.134958  normal  1 
 
 
-
 
NC_013132  Cpin_6260  methylmalonyl-CoA mutase, large subunit  29.48 
 
 		 517 aa  137  6.0000000000000005e-31  Chitinophaga pinensis DSM 2588  Bacteria  normal  1  normal  0.593051 
 
 
-
 
NC_009719  Plav_1702  methylmalonyl-CoA mutase  28.35 
 
 		 718 aa  137  6.0000000000000005e-31  Parvibaculum lavamentivorans DS-1  Bacteria  normal  1  normal  0.0321557 
 
 
-
 
NC_009667  Oant_2001  methylmalonyl-CoA mutase  29.34 
 
 		 714 aa  137  7.000000000000001e-31  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  1  n/a   
 
 
-
 
NC_009428  Rsph17025_2300  methylmalonyl-CoA mutase  28.78 
 
 		 709 aa  135  1.9999999999999998e-30  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008576  Mmc1_0388  methylmalonyl-CoA mutase  27.43 
 
 		 714 aa  135  1.9999999999999998e-30  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007298  Daro_4006  methylmalonyl-CoA mutase  26.76 
 
 		 716 aa  134  3.9999999999999996e-30  Dechloromonas aromatica RCB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007333  Tfu_2762  methylmalonyl-CoA mutase  28.09 
 
 		 740 aa  134  6.999999999999999e-30  Thermobifida fusca YX  Bacteria  normal  1  n/a   
 
 
-
 
NC_013169  Ksed_22170  methylmalonyl-CoA mutase  29.54 
 
 		 754 aa  134  6.999999999999999e-30  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.366718  normal  0.398515 
 
 
-
 
NC_010320  Teth514_1855  methylmalonyl-CoA mutase, large subunit  28.43 
 
 		 560 aa  133  1.0000000000000001e-29  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_008699  Noca_3545  methylmalonyl-CoA mutase  31.17 
 
 		 569 aa  132  1.0000000000000001e-29  Nocardioides sp. JS614  Bacteria  normal  1  n/a   
 
 
-
 
NC_011988  Avi_5687  methylmalonyl-CoA mutase  30 
 
 		 712 aa  132  2.0000000000000002e-29  Agrobacterium vitis S4  Bacteria  normal  1  n/a   
 
 
-
 
NC_007514  Cag_1222  methylmalonyl-CoA mutase N-terminal domain-containing protein  29.47 
 
 		 597 aa  131  3e-29  Chlorobium chlorochromatii CaD3  Bacteria  normal  1  n/a   
 
 
-
 
NC_013510  Tcur_2505  methylmalonyl-CoA mutase, large subunit  29.13 
 
 		 736 aa  130  5.0000000000000004e-29  Thermomonospora curvata DSM 43183  Bacteria  hitchhiker  0.000422516  n/a   
 
 
-
 
NC_009801  EcE24377A_3244  methylmalonyl-CoA mutase  35.71 
 
 		 714 aa  130  6e-29  Escherichia coli E24377A  Bacteria  normal  0.98625  n/a   
 
 
-
 
CP001509  ECD_02748  methylmalonyl-CoA mutase  35.71 
 
 		 714 aa  130  7.000000000000001e-29  Escherichia coli BL21(DE3)  Bacteria  normal  1  n/a   
 
 
-
 
CP001637  EcDH1_0776  methylmalonyl-CoA mutase, large subunit  35.71 
 
 		 714 aa  130  7.000000000000001e-29  Escherichia coli DH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_012892  B21_02711  hypothetical protein  35.71 
 
 		 714 aa  130  7.000000000000001e-29  Escherichia coli BL21  Bacteria  normal  1  n/a   
 
 
-
 
NC_011353  ECH74115_4213  methylmalonyl-CoA mutase  35.71 
 
 		 714 aa  130  7.000000000000001e-29  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009800  EcHS_A3075  methylmalonyl-CoA mutase  35.71 
 
 		 714 aa  130  7.000000000000001e-29  Escherichia coli HS  Bacteria  normal  1  n/a   
 
 
-
 
NC_010468  EcolC_0793  methylmalonyl-CoA mutase  35.71 
 
 		 714 aa  130  7.000000000000001e-29  Escherichia coli ATCC 8739  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009379  Pnuc_0910  methylmalonyl-CoA mutase  33.96 
 
 		 739 aa  130  7.000000000000001e-29  Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1  Bacteria  normal  0.736612  n/a   
 
 
-
 
NC_010002  Daci_3753  methylmalonyl-CoA mutase  32.58 
 
 		 738 aa  129  1.0000000000000001e-28  Delftia acidovorans SPH-1  Bacteria  normal  0.801598  normal  0.879758 
 
 
-
 
NC_010814  Glov_3260  methylmalonyl-CoA mutase, large subunit  35.84 
 
 		 713 aa  129  1.0000000000000001e-28  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_010498  EcSMS35_3053  methylmalonyl-CoA mutase  35.27 
 
 		 714 aa  129  1.0000000000000001e-28  Escherichia coli SMS-3-5  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008786  Veis_3398  methylmalonyl-CoA mutase  26.34 
 
 		 731 aa  129  1.0000000000000001e-28  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.526303  normal  1 
 
 
-
 
NC_008825  Mpe_A1014  methylmalonyl-CoA mutase  34.48 
 
 		 719 aa  129  1.0000000000000001e-28  Methylibium petroleiphilum PM1  Bacteria  normal  1  normal  0.856859 
 
 
-
 
NC_009620  Smed_4237  methylmalonyl-CoA mutase  36.89 
 
 		 712 aa  129  1.0000000000000001e-28  Sinorhizobium medicae WSM419  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007512  Plut_1291  methylmalonyl-CoA mutase  26.03 
 
 		 588 aa  129  2.0000000000000002e-28  Chlorobium luteolum DSM 273  Bacteria  normal  1  normal  0.788589 
 
 
-
 
NC_011662  Tmz1t_3486  methylmalonyl-CoA mutase  36 
 
 		 721 aa  129  2.0000000000000002e-28  Thauera sp. MZ1T  Bacteria  normal  1  n/a   
 
 
-
 
NC_009485  BBta_3021  methylmalonyl-CoA mutase  28.98 
 
 		 718 aa  128  2.0000000000000002e-28  Bradyrhizobium sp. BTAi1  Bacteria  normal  1  normal  0.954275 
 
 
-
 
NC_013411  GYMC61_0279  methylmalonyl-CoA mutase  26.77 
 
 		 731 aa  128  3e-28  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012793  GWCH70_2294  methylmalonyl-CoA mutase  25.34 
 
 		 731 aa  127  4.0000000000000003e-28  Geobacillus sp. WCH70  Bacteria  normal  0.895743  n/a   
 
 
-
 
NC_010531  Pnec_0932  methylmalonyl-CoA mutase  25.49 
 
 		 724 aa  127  6e-28  Polynucleobacter necessarius subsp. necessarius STIR1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012852  Rleg_6098  methylmalonyl-CoA mutase  30.05 
 
 		 712 aa  127  6e-28  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.23929  normal  0.554736 
 
 
-
 
NC_009943  Dole_0079  methylmalonyl-CoA mutase  25.6 
 
 		 706 aa  127  6e-28  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.373309  n/a   
 
 
-
 
NC_010831  Cphamn1_1173  methylmalonyl-CoA mutase, large subunit  36.51 
 
 		 1106 aa  127  7e-28  Chlorobium phaeobacteroides BS1  Bacteria  normal  1  decreased coverage  0.00593374 
 
 
-
 
NC_008752  Aave_2510  methylmalonyl-CoA mutase  34.22 
 
 		 722 aa  127  7e-28  Acidovorax citrulli AAC00-1  Bacteria  normal  1  normal  0.178476 
 
 
-
 
NC_009441  Fjoh_0013  methylmalonyl-CoA mutase  32.12 
 
 		 453 aa  127  8.000000000000001e-28  Flavobacterium johnsoniae UW101  Bacteria  normal  0.431519  n/a   
 
 
-
 
NC_010524  Lcho_2697  methylmalonyl-CoA mutase  35.11 
 
 		 720 aa  127  8.000000000000001e-28  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.20812 
 
 
-
 
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