More than 300 homologs were found in PanDaTox collection
for query gene Sros_5820 on replicon NC_013595
Organism: Streptosporangium roseum DSM 43021



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_013595  Sros_5820  ABC-type sugar transport system periplasmic component-like protein  100 
 
 		 447 aa  920    Streptosporangium roseum DSM 43021  Bacteria  normal  1  normal  0.8778 
 
 
-
 
NC_010320  Teth514_1099  extracellular solute-binding protein  28.12 
 
 		 457 aa  121  1.9999999999999998e-26  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_009616  Tmel_1017  extracellular solute-binding protein  27.2 
 
 		 417 aa  121  3e-26  Thermosipho melanesiensis BI429  Bacteria  normal  0.0416471  n/a   
 
 
-
 
NC_010571  Oter_1748  extracellular solute-binding protein  28.04 
 
 		 481 aa  105  2e-21  Opitutus terrae PB90-1  Bacteria  normal  0.922527  normal  1 
 
 
-
 
NC_008698  Tpen_1453  extracellular solute-binding protein  28.45 
 
 		 415 aa  92  2e-17  Thermofilum pendens Hrk 5  Archaea  normal  0.0104666  n/a   
 
 
-
 
NC_010320  Teth514_2201  extracellular solute-binding protein  25.57 
 
 		 420 aa  90.1  7e-17  Thermoanaerobacter sp. X514  Bacteria  normal  0.455559  n/a   
 
 
-
 
NC_013525  Tter_0508  extracellular solute-binding protein family 1  24.34 
 
 		 514 aa  87.8  4e-16  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_012669  Bcav_3988  extracellular solute-binding protein family 1  24.69 
 
 		 422 aa  87  5e-16  Beutenbergia cavernae DSM 12333  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013411  GYMC61_1727  extracellular solute-binding protein family 1  26.91 
 
 		 422 aa  80.9  0.00000000000004  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_010001  Cphy_0291  extracellular solute-binding protein  25 
 
 		 449 aa  80.9  0.00000000000004  Clostridium phytofermentans ISDg  Bacteria  normal  1  n/a   
 
 
-
 
NC_009939  Dgeo_2919  ABC-type sugar transport system, periplasmic component  25.06 
 
 		 407 aa  80.1  0.00000000000007  Deinococcus geothermalis DSM 11300  Bacteria  n/a    n/a   
 
 
-
 
NC_011661  Dtur_0381  extracellular solute-binding protein family 1  25.5 
 
 		 421 aa  80.1  0.00000000000008  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_011884  Cyan7425_4083  extracellular solute-binding protein family 1  24.74 
 
 		 417 aa  78.6  0.0000000000002  Cyanothece sp. PCC 7425  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013205  Aaci_0913  extracellular solute-binding protein family 1  27.57 
 
 		 421 aa  77.4  0.0000000000005  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  1  n/a   
 
 
-
 
NC_010320  Teth514_1181  extracellular solute-binding protein  24.26 
 
 		 413 aa  75.9  0.000000000001  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.0000595288  n/a   
 
 
-
 
NC_012669  Bcav_3000  extracellular solute-binding protein family 1  25.46 
 
 		 450 aa  75.1  0.000000000002  Beutenbergia cavernae DSM 12333  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009620  Smed_4916  extracellular solute-binding protein  24.1 
 
 		 410 aa  74.7  0.000000000003  Sinorhizobium medicae WSM419  Bacteria  normal  0.06645  normal  0.512511 
 
 
-
 
NC_010003  Pmob_0289  extracellular solute-binding protein  27.27 
 
 		 437 aa  74.3  0.000000000004  Petrotoga mobilis SJ95  Bacteria  unclonable  0.00000019091  n/a   
 
 
-
 
NC_011899  Hore_20520  extracellular solute-binding protein family 1  24.26 
 
 		 417 aa  73.9  0.000000000006  Halothermothrix orenii H 168  Bacteria  normal  0.561553  n/a   
 
 
-
 
NC_013739  Cwoe_4883  extracellular solute-binding protein family 1  26.61 
 
 		 436 aa  73.6  0.000000000007  Conexibacter woesei DSM 14684  Bacteria  normal  0.504344  normal  1 
 
 
-
 
NC_013411  GYMC61_2731  extracellular solute-binding protein family 1  24.72 
 
 		 454 aa  72.8  0.00000000001  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_014165  Tbis_3251  extracellular solute-binding protein family 1  29.37 
 
 		 427 aa  73.2  0.00000000001  Thermobispora bispora DSM 43833  Bacteria  normal  0.829082  normal  1 
 
 
-
 
NC_013172  Bfae_01220  ABC-type sugar transport system, periplasmic component  21.7 
 
 		 466 aa  72.8  0.00000000001  Brachybacterium faecium DSM 4810  Bacteria  normal  1  n/a   
 
 
-
 
NC_012034  Athe_0399  extracellular solute-binding protein family 1  27.6 
 
 		 408 aa  70.5  0.00000000006  Anaerocellum thermophilum DSM 6725  Bacteria  unclonable  0.00000000195685  n/a   
 
 
-
 
NC_012793  GWCH70_1392  extracellular solute-binding protein family 1  25.41 
 
 		 445 aa  70.5  0.00000000006  Geobacillus sp. WCH70  Bacteria  normal  1  n/a   
 
 
-
 
NC_011988  Avi_5736  ABC transporter, substrate-binding protein  26.37 
 
 		 410 aa  70.1  0.00000000008  Agrobacterium vitis S4  Bacteria  normal  0.214535  n/a   
 
 
-
 
NC_010003  Pmob_0721  extracellular solute-binding protein  26.22 
 
 		 437 aa  70.1  0.00000000008  Petrotoga mobilis SJ95  Bacteria  normal  0.540981  n/a   
 
 
-
 
NC_013595  Sros_3538  Maltose-binding periplasmic protein/domains- like protein  26.6 
 
 		 406 aa  69.3  0.0000000001  Streptosporangium roseum DSM 43021  Bacteria  normal  0.385239  normal  1 
 
 
-
 
NC_008010  Dgeo_2696  extracellular solute-binding protein  26.67 
 
 		 420 aa  69.3  0.0000000001  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.240659  n/a   
 
 
-
 
NC_008262  CPR_0904  ABC transporter, periplasmic substrate-binding protein, putative  24.35 
 
 		 439 aa  69.7  0.0000000001  Clostridium perfringens SM101  Bacteria  decreased coverage  0.00221898  n/a   
 
 
-
 
NC_013526  Tter_2524  extracellular solute-binding protein family 1  22.72 
 
 		 483 aa  69.7  0.0000000001  Thermobaculum terrenum ATCC BAA-798  Bacteria  decreased coverage  0.00000000331289  n/a   
 
 
-
 
NC_014212  Mesil_0955  extracellular solute-binding protein family 1  25.82 
 
 		 437 aa  68.6  0.0000000002  Meiothermus silvanus DSM 9946  Bacteria  normal  1  normal  0.152307 
 
 
-
 
NC_011899  Hore_19770  extracellular solute-binding protein family 1  26.74 
 
 		 423 aa  68.6  0.0000000002  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_014212  Mesil_2466  extracellular solute-binding protein family 1  23.18 
 
 		 415 aa  68.9  0.0000000002  Meiothermus silvanus DSM 9946  Bacteria  normal  1  normal  0.0930087 
 
 
-
 
NC_013947  Snas_2758  extracellular solute-binding protein family 1  24.12 
 
 		 423 aa  68.2  0.0000000003  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.736779  normal  1 
 
 
-
 
NC_010483  TRQ2_1696  extracellular solute-binding protein  26.06 
 
 		 436 aa  68.2  0.0000000003  Thermotoga sp. RQ2  Bacteria  hitchhiker  0.00506774  n/a   
 
 
-
 
NC_008243  Meso_4520  extracellular solute-binding protein  26.76 
 
 		 415 aa  68.2  0.0000000003  Chelativorans sp. BNC1  Bacteria  normal  1  n/a   
 
 
-
 
NC_012852  Rleg_6156  extracellular solute-binding protein family 1  27.41 
 
 		 410 aa  68.2  0.0000000003  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.889741  hitchhiker  0.000305646 
 
 
-
 
NC_010483  TRQ2_0970  extracellular solute-binding protein  25.86 
 
 		 411 aa  67.4  0.0000000004  Thermotoga sp. RQ2  Bacteria  hitchhiker  0.000309876  n/a   
 
 
-
 
NC_009486  Tpet_0954  extracellular solute-binding protein  25.86 
 
 		 411 aa  67.8  0.0000000004  Thermotoga petrophila RKU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013526  Tter_2218  extracellular solute-binding protein family 1  24.75 
 
 		 479 aa  67.8  0.0000000004  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00910899  n/a   
 
 
-
 
NC_014165  Tbis_1886  extracellular solute-binding protein family 1  26.09 
 
 		 435 aa  67  0.0000000006  Thermobispora bispora DSM 43833  Bacteria  normal  1  normal  0.23125 
 
 
-
 
NC_012669  Bcav_3712  extracellular solute-binding protein family 1  24.47 
 
 		 421 aa  67  0.0000000007  Beutenbergia cavernae DSM 12333  Bacteria  normal  1  normal  0.411366 
 
 
-
 
NC_013205  Aaci_0795  extracellular solute-binding protein family 1  24.54 
 
 		 460 aa  66.6  0.0000000008  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.215252  n/a   
 
 
-
 
NC_013501  Rmar_0358  extracellular solute-binding protein family 1  24.09 
 
 		 441 aa  66.6  0.0000000009  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_013946  Mrub_0045  extracellular solute-binding protein family 1  23.68 
 
 		 414 aa  66.2  0.000000001  Meiothermus ruber DSM 1279  Bacteria  normal  0.713374  normal  1 
 
 
-
 
NC_008262  CPR_0476  ABC transporter, substrate-binding protein  26.1 
 
 		 427 aa  65.9  0.000000001  Clostridium perfringens SM101  Bacteria  normal  1  n/a   
 
 
-
 
NC_013159  Svir_11620  ABC-type sugar transport system, periplasmic component  25.07 
 
 		 426 aa  65.9  0.000000001  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011899  Hore_04610  extracellular solute-binding protein family 1  25.15 
 
 		 431 aa  65.9  0.000000001  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_013526  Tter_1999  extracellular solute-binding protein family 1  24.87 
 
 		 468 aa  65.9  0.000000001  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  1  n/a   
 
 
-
 
NC_013526  Tter_2042  extracellular solute-binding protein family 1  26.57 
 
 		 483 aa  66.2  0.000000001  Thermobaculum terrenum ATCC BAA-798  Bacteria  decreased coverage  0.0000000305417  n/a   
 
 
-
 
NC_013739  Cwoe_3957  extracellular solute-binding protein family 1  28.13 
 
 		 432 aa  65.5  0.000000002  Conexibacter woesei DSM 14684  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013411  GYMC61_2959  extracellular solute-binding protein family 1  24 
 
 		 437 aa  65.5  0.000000002  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013595  Sros_3339  Maltose-binding periplasmic protein/domains- like protein  26.11 
 
 		 431 aa  64.7  0.000000003  Streptosporangium roseum DSM 43021  Bacteria  normal  1  normal  0.202326 
 
 
-
 
NC_013093  Amir_0348  extracellular solute-binding protein family 1  27.36 
 
 		 419 aa  64.7  0.000000003  Actinosynnema mirum DSM 43827  Bacteria  normal  1  n/a   
 
 
-
 
NC_011371  Rleg2_6572  extracellular solute-binding protein family 1  29.21 
 
 		 410 aa  65.1  0.000000003  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  decreased coverage  0.00103217  normal  0.480926 
 
 
-
 
NC_011145  AnaeK_4267  extracellular solute-binding protein family 1  26.11 
 
 		 400 aa  64.3  0.000000004  Anaeromyxobacter sp. K  Bacteria  normal  1  n/a   
 
 
-
 
NC_012034  Athe_2310  extracellular solute-binding protein family 1  24.36 
 
 		 425 aa  63.9  0.000000005  Anaerocellum thermophilum DSM 6725  Bacteria  unclonable  0.00000000523246  n/a   
 
 
-
 
NC_009667  Oant_2485  extracellular solute-binding protein  26.07 
 
 		 415 aa  63.2  0.000000009  Ochrobactrum anthropi ATCC 49188  Bacteria  decreased coverage  0.00421769  n/a   
 
 
-
 
NC_007413  Ava_3042  extracellular solute-binding protein  25.97 
 
 		 406 aa  63.2  0.00000001  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0658677  normal  1 
 
 
-
 
NC_008261  CPF_2652  putative maltose/maltodextrin ABC transporter, maltose/maltodextrin-binding protein  23.77 
 
 		 408 aa  62.8  0.00000001  Clostridium perfringens ATCC 13124  Bacteria  normal  1  n/a   
 
 
-
 
NC_008541  Arth_3387  extracellular solute-binding protein  26.67 
 
 		 447 aa  62.4  0.00000001  Arthrobacter sp. FB24  Bacteria  normal  0.278202  n/a   
 
 
-
 
NC_011772  BCG9842_B1120  putative maltosaccharide ABC transporter, maltosaccharide-binding protein  24.13 
 
 		 419 aa  63.2  0.00000001  Bacillus cereus G9842  Bacteria  hitchhiker  0.0000383609  normal  1 
 
 
-
 
NC_011898  Ccel_3350  extracellular solute-binding protein family 1  28.64 
 
 		 461 aa  62.8  0.00000001  Clostridium cellulolyticum H10  Bacteria  normal  1  n/a   
 
 
-
 
NC_011831  Cagg_2267  extracellular solute-binding protein family 1  25 
 
 		 445 aa  62.8  0.00000001  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  hitchhiker  0.00064551 
 
 
-
 
NC_009667  Oant_0354  extracellular solute-binding protein  24.15 
 
 		 419 aa  62.8  0.00000001  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.188589  n/a   
 
 
-
 
NC_013947  Snas_0203  extracellular solute-binding protein family 1  25.47 
 
 		 441 aa  62  0.00000002  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.346278  normal  0.123927 
 
 
-
 
NC_007413  Ava_1229  extracellular solute-binding protein  26.46 
 
 		 461 aa  62.4  0.00000002  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0257979  normal  0.868479 
 
 
-
 
NC_011658  BCAH187_A0700  putative glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein  26.6 
 
 		 458 aa  61.6  0.00000002  Bacillus cereus AH187  Bacteria  normal  1  n/a   
 
 
-
 
NC_008025  Dgeo_0687  extracellular solute-binding protein  25.68 
 
 		 407 aa  62  0.00000002  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.376534  normal  0.15795 
 
 
-
 
NC_011772  BCG9842_B4733  putative glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein  26.6 
 
 		 458 aa  62  0.00000002  Bacillus cereus G9842  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012669  Bcav_0648  extracellular solute-binding protein family 1  21.61 
 
 		 447 aa  62  0.00000002  Beutenbergia cavernae DSM 12333  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008010  Dgeo_2726  extracellular solute-binding protein  23.35 
 
 		 437 aa  61.6  0.00000003  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.290956  n/a   
 
 
-
 
NC_013411  GYMC61_2845  extracellular solute-binding protein family 1  27.1 
 
 		 439 aa  61.6  0.00000003  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_008578  Acel_0434  extracellular solute-binding protein  25.97 
 
 		 452 aa  61.2  0.00000003  Acidothermus cellulolyticus 11B  Bacteria  normal  1  normal  0.396307 
 
 
-
 
NC_012669  Bcav_1680  extracellular solute-binding protein family 1  24.69 
 
 		 430 aa  61.6  0.00000003  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.173253  normal  1 
 
 
-
 
NC_012669  Bcav_1708  extracellular solute-binding protein family 1  26.11 
 
 		 458 aa  61.2  0.00000003  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.190784  normal  1 
 
 
-
 
NC_009620  Smed_4017  extracellular solute-binding protein  24.31 
 
 		 435 aa  61.6  0.00000003  Sinorhizobium medicae WSM419  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014165  Tbis_1105  extracellular solute-binding protein family 1  27.51 
 
 		 443 aa  61.2  0.00000004  Thermobispora bispora DSM 43833  Bacteria  normal  0.698754  normal  0.0706181 
 
 
-
 
NC_013739  Cwoe_5802  extracellular solute-binding protein family 1  25.14 
 
 		 444 aa  61.2  0.00000004  Conexibacter woesei DSM 14684  Bacteria  normal  1  normal  0.0809589 
 
 
-
 
NC_010320  Teth514_0753  extracellular solute-binding protein  23.88 
 
 		 429 aa  60.8  0.00000005  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.00037903  n/a   
 
 
-
 
NC_008262  CPR_2338  maltose-binding periplasmic protein precursor  24.94 
 
 		 408 aa  60.8  0.00000005  Clostridium perfringens SM101  Bacteria  normal  1  n/a   
 
 
-
 
NC_013595  Sros_9091  ABC-type sugar transport system periplasmic component-like protein  25.2 
 
 		 422 aa  60.8  0.00000005  Streptosporangium roseum DSM 43021  Bacteria  normal  0.306335  normal  1 
 
 
-
 
NC_013530  Xcel_1138  extracellular solute-binding protein family 1  24.92 
 
 		 423 aa  60.8  0.00000005  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.443513  n/a   
 
 
-
 
NC_011773  BCAH820_0625  putative glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein  26.33 
 
 		 458 aa  60.8  0.00000005  Bacillus cereus AH820  Bacteria  n/a    normal  1 
 
 
-
 
NC_009616  Tmel_0753  extracellular solute-binding protein  26.57 
 
 		 437 aa  60.5  0.00000006  Thermosipho melanesiensis BI429  Bacteria  normal  1  n/a   
 
 
-
 
NC_003909  BCE_0632  glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein, putative  25.8 
 
 		 458 aa  60.1  0.00000007  Bacillus cereus ATCC 10987  Bacteria  normal  1  n/a   
 
 
-
 
NC_007760  Adeh_4136  ABC sugar transporter, periplasmic ligand binding protein  26.62 
 
 		 400 aa  60.5  0.00000007  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  1  n/a   
 
 
-
 
NC_010623  Bphy_4057  extracellular solute-binding protein  26.09 
 
 		 410 aa  60.5  0.00000007  Burkholderia phymatum STM815  Bacteria  normal  1  normal  1 
 
 
-
 
NC_005957  BT9727_0480  glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein  26.06 
 
 		 458 aa  60.1  0.00000008  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  1  n/a   
 
 
-
 
NC_006274  BCZK0482  glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein  26.06 
 
 		 458 aa  60.1  0.00000008  Bacillus cereus E33L  Bacteria  normal  1  n/a   
 
 
-
 
NC_014210  Ndas_0659  extracellular solute-binding protein family 1  24.6 
 
 		 425 aa  60.1  0.00000008  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.579585  normal  0.728331 
 
 
-
 
NC_012669  Bcav_3572  extracellular solute-binding protein family 1  25.75 
 
 		 427 aa  60.1  0.00000008  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.405751  normal  1 
 
 
-
 
NC_005945  BAS0538  glycerol-3-phosphate ABC transporter glycerol-3-phosphate-binding protein  26.06 
 
 		 458 aa  60.1  0.00000009  Bacillus anthracis str. Sterne  Bacteria  normal  0.406699  n/a   
 
 
-
 
NC_007530  GBAA_0569  glycerol-3-phosphate ABC transporter glycerol-3-phosphate-binding protein  26.06 
 
 		 458 aa  60.1  0.00000009  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  1  n/a   
 
 
-
 
NC_012034  Athe_2574  extracellular solute-binding protein family 1  25.81 
 
 		 401 aa  59.7  0.00000009  Anaerocellum thermophilum DSM 6725  Bacteria  unclonable  0.00000000602333  n/a   
 
 
-
 
NC_011725  BCB4264_A0606  putative glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein  26.06 
 
 		 458 aa  59.3  0.0000001  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_009674  Bcer98_2714  extracellular solute-binding protein  25.19 
 
 		 419 aa  59.3  0.0000001  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.182746  n/a   
 
 
-
 
NC_007413  Ava_3685  extracellular solute-binding protein  24.6 
 
 		 432 aa  58.9  0.0000002  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009439  Pmen_3132  maltose ABC transporter periplasmic protein  27.71 
 
 		 395 aa  59.3  0.0000002  Pseudomonas mendocina ymp  Bacteria  normal  0.0559599  normal  0.0111617 
 
 
-
 
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