More than 300 homologs were found in PanDaTox collection
for query gene Mpal_0048 on replicon NC_011832
Organism: Methanosphaerula palustris E1-9c



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011832  Mpal_0048  putative PAS/PAC sensor protein  100 
 
 
255 aa  513  1e-144  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_009483  Gura_2117  putative PAS/PAC sensor protein  41.34 
 
 
257 aa  170  2e-41  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_009712  Mboo_1807  putative PAS/PAC sensor protein  47.75 
 
 
258 aa  162  7e-39  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal  0.254511 
 
 
-
 
NC_010551  BamMC406_1235  multi-sensor hybrid histidine kinase  35.91 
 
 
989 aa  156  3e-37  Burkholderia ambifaria MC40-6  Bacteria  normal  0.172784  normal 
 
 
-
 
NC_011831  Cagg_1360  putative PAS/PAC sensor protein  37.9 
 
 
429 aa  154  9e-37  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00110028  hitchhiker  0.000665614 
 
 
-
 
NC_007796  Mhun_2637  putative PAS/PAC sensor protein  39.82 
 
 
461 aa  153  2e-36  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_007413  Ava_3003  PAS/PAC sensor hybrid histidine kinase  36.8 
 
 
498 aa  153  2.9999999999999998e-36  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_010623  Bphy_4529  multi-sensor hybrid histidine kinase  35.14 
 
 
989 aa  151  8.999999999999999e-36  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_014248  Aazo_1725  multi-sensor signal transduction histidine kinase  37.55 
 
 
499 aa  149  4e-35  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_3008  multi-sensor hybrid histidine kinase  43.55 
 
 
953 aa  145  8.000000000000001e-34  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_007796  Mhun_0455  response regulator receiver domain-containing protein  52.8 
 
 
238 aa  140  1.9999999999999998e-32  Methanospirillum hungatei JF-1  Archaea  normal  normal  0.21261 
 
 
-
 
NC_007796  Mhun_1724  response regulator receiver domain-containing protein  52.55 
 
 
352 aa  140  1.9999999999999998e-32  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_007955  Mbur_0841  response regulator receiver  56.35 
 
 
135 aa  139  3e-32  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_013161  Cyan8802_0439  response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor  42.62 
 
 
455 aa  138  7e-32  Cyanothece sp. PCC 8802  Bacteria  normal  normal  0.444664 
 
 
-
 
NC_011832  Mpal_1773  response regulator receiver sensor signal transduction histidine kinase  53.12 
 
 
386 aa  137  1e-31  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_011726  PCC8801_0428  response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor  42.08 
 
 
455 aa  137  2e-31  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_007355  Mbar_A3448  putative transcriptional regulator  55.65 
 
 
143 aa  136  3.0000000000000003e-31  Methanosarcina barkeri str. Fusaro  Archaea  normal  0.132297  normal  0.0606491 
 
 
-
 
NC_009712  Mboo_1808  putative PAS/PAC sensor protein  42.31 
 
 
603 aa  135  5e-31  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal  0.268482 
 
 
-
 
NC_007908  Rfer_0895  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  37.05 
 
 
701 aa  135  6.0000000000000005e-31  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_009712  Mboo_1813  response regulator receiver protein  45.39 
 
 
316 aa  133  1.9999999999999998e-30  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.445517  normal  0.445863 
 
 
-
 
NC_007498  Pcar_2709  two component signal transduction response regulator  41.71 
 
 
429 aa  132  3.9999999999999996e-30  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_1460  putative PAS/PAC sensor protein  33.71 
 
 
474 aa  132  5e-30  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.81808 
 
 
-
 
NC_011884  Cyan7425_3178  response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor  38.3 
 
 
426 aa  132  5e-30  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_008554  Sfum_2639  multi-sensor hybrid histidine kinase  43.4 
 
 
817 aa  132  6.999999999999999e-30  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_1730  multi-sensor signal transduction histidine kinase  52.42 
 
 
591 aa  131  1.0000000000000001e-29  Geobacter uraniireducens Rf4  Bacteria  normal  0.319599  n/a   
 
 
-
 
NC_011729  PCC7424_4564  response regulator receiver sensor signal transduction histidine kinase  48.28 
 
 
376 aa  130  3e-29  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.531352 
 
 
-
 
NC_011884  Cyan7425_4302  signal transduction histidine kinase  49.63 
 
 
343 aa  129  4.0000000000000003e-29  Cyanothece sp. PCC 7425  Bacteria  normal  0.219335  normal  0.321802 
 
 
-
 
NC_009712  Mboo_1311  putative PAS/PAC sensor protein  41.67 
 
 
340 aa  129  4.0000000000000003e-29  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal  0.187179 
 
 
-
 
NC_011832  Mpal_0573  response regulator receiver protein  39.06 
 
 
261 aa  129  5.0000000000000004e-29  Methanosphaerula palustris E1-9c  Archaea  normal  0.666159  normal  0.332219 
 
 
-
 
NC_009972  Haur_0985  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  38.5 
 
 
704 aa  128  7.000000000000001e-29  Herpetosiphon aurantiacus ATCC 23779  Bacteria  decreased coverage  0.000494124  n/a   
 
 
-
 
NC_007948  Bpro_3511  response regulator receiver sensor signal transduction histidine kinase  46.97 
 
 
384 aa  127  1.0000000000000001e-28  Polaromonas sp. JS666  Bacteria  normal  normal  0.253652 
 
 
-
 
NC_007955  Mbur_2285  response regulator receiver  50.39 
 
 
130 aa  128  1.0000000000000001e-28  Methanococcoides burtonii DSM 6242  Archaea  hitchhiker  0.000158247  n/a   
 
 
-
 
NC_007519  Dde_3002  putative PAS/PAC sensor protein  37.77 
 
 
469 aa  125  8.000000000000001e-28  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.345319  n/a   
 
 
-
 
NC_008751  Dvul_0434  putative PAS/PAC sensor protein  39.89 
 
 
458 aa  125  1e-27  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_007413  Ava_4326  PAS/PAC sensor hybrid histidine kinase  33.2 
 
 
571 aa  124  2e-27  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_011769  DvMF_2677  response regulator receiver sensor hybrid histidine kinase  49.17 
 
 
636 aa  124  2e-27  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.068934 
 
 
-
 
NC_013173  Dbac_0866  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  42.08 
 
 
701 aa  124  2e-27  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.711392  n/a   
 
 
-
 
NC_009712  Mboo_2407  response regulator receiver protein  52.85 
 
 
182 aa  123  3e-27  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal 
 
 
-
 
NC_007955  Mbur_1557  response regulator receiver  50.41 
 
 
131 aa  122  4e-27  Methanococcoides burtonii DSM 6242  Archaea  hitchhiker  0.000000412225  n/a   
 
 
-
 
NC_011729  PCC7424_1114  response regulator receiver sensor signal transduction histidine kinase  45.99 
 
 
373 aa  122  6e-27  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_009712  Mboo_1528  response regulator receiver protein  45.39 
 
 
450 aa  120  1.9999999999999998e-26  Candidatus Methanoregula boonei 6A8  Archaea  hitchhiker  0.00374994  normal  0.77554 
 
 
-
 
NC_007955  Mbur_0883  response regulator receiver  37.7 
 
 
273 aa  120  3e-26  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_007796  Mhun_3039  response regulator receiver sensor signal transduction histidine kinase  42.04 
 
 
355 aa  119  3.9999999999999996e-26  Methanospirillum hungatei JF-1  Archaea  normal  0.610599  normal 
 
 
-
 
NC_009712  Mboo_1358  putative PAS/PAC sensor protein  40.12 
 
 
404 aa  119  4.9999999999999996e-26  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.873442  normal  0.0258422 
 
 
-
 
NC_007796  Mhun_2645  putative PAS/PAC sensor protein  36.41 
 
 
336 aa  118  9e-26  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_007948  Bpro_3510  PAS/PAC sensor hybrid histidine kinase  34.65 
 
 
521 aa  118  9e-26  Polaromonas sp. JS666  Bacteria  normal  normal  0.269968 
 
 
-
 
NC_009712  Mboo_1912  response regulator receiver protein  38.8 
 
 
263 aa  118  9.999999999999999e-26  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.181503  normal  0.732361 
 
 
-
 
NC_007796  Mhun_2686  putative PAS/PAC sensor protein  39.88 
 
 
337 aa  118  9.999999999999999e-26  Methanospirillum hungatei JF-1  Archaea  normal  normal  0.209027 
 
 
-
 
NC_007908  Rfer_0893  response regulator receiver sensor signal transduction histidine kinase  49.19 
 
 
359 aa  117  9.999999999999999e-26  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_2337  signal transduction histidine kinase  48.36 
 
 
352 aa  117  1.9999999999999998e-25  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_009712  Mboo_1497  putative PAS/PAC sensor protein  36.67 
 
 
380 aa  114  1.0000000000000001e-24  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.506851  normal  0.137069 
 
 
-
 
NC_009712  Mboo_1242  multi-sensor signal transduction histidine kinase  42.36 
 
 
472 aa  112  5e-24  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.41521  normal 
 
 
-
 
NC_009712  Mboo_0900  response regulator receiver protein  46.67 
 
 
126 aa  112  8.000000000000001e-24  Candidatus Methanoregula boonei 6A8  Archaea  normal  hitchhiker  0.000110071 
 
 
-
 
NC_007413  Ava_0066  response regulator receiver sensor signal transduction histidine kinase  47.54 
 
 
377 aa  111  1.0000000000000001e-23  Anabaena variabilis ATCC 29413  Bacteria  normal  0.359193  normal  0.0132857 
 
 
-
 
NC_013730  Slin_3896  two component transcriptional regulator, LytTR family  43.94 
 
 
245 aa  111  1.0000000000000001e-23  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.356034 
 
 
-
 
NC_011832  Mpal_2212  response regulator receiver protein  46.67 
 
 
122 aa  110  2.0000000000000002e-23  Methanosphaerula palustris E1-9c  Archaea  normal  0.092497  normal  0.290386 
 
 
-
 
NC_008751  Dvul_2282  histidine kinase  43.75 
 
 
667 aa  110  3e-23  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_009712  Mboo_1488  response regulator receiver protein  32.35 
 
 
450 aa  109  4.0000000000000004e-23  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal  0.379239 
 
 
-
 
NC_007796  Mhun_0118  putative PAS/PAC sensor protein  38.1 
 
 
265 aa  109  5e-23  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_007413  Ava_3669  response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor  30.83 
 
 
432 aa  108  6e-23  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_014230  CA2559_08681  transcriptional regulator  40.16 
 
 
240 aa  106  4e-22  Croceibacter atlanticus HTCC2559  Bacteria  normal  0.803849  n/a   
 
 
-
 
NC_007796  Mhun_2576  response regulator receiver domain-containing protein  44.17 
 
 
122 aa  102  8e-21  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_009712  Mboo_1007  putative GAF sensor protein  47.11 
 
 
311 aa  102  8e-21  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.164021  normal  0.860345 
 
 
-
 
NC_009712  Mboo_2336  response regulator receiver protein  40.65 
 
 
355 aa  97.8  2e-19  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.404573  normal  0.642469 
 
 
-
 
NC_009767  Rcas_3118  response regulator receiver/ANTAR domain-containing protein  44.35 
 
 
196 aa  97.1  3e-19  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_007796  Mhun_1200  response regulator receiver domain-containing protein  34.29 
 
 
248 aa  95.9  5e-19  Methanospirillum hungatei JF-1  Archaea  normal  0.0783054  normal  0.0763711 
 
 
-
 
NC_011831  Cagg_2933  response regulator receiver and ANTAR domain protein  42.5 
 
 
194 aa  94.7  1e-18  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.0803562  normal  0.225953 
 
 
-
 
NC_013730  Slin_3427  two component transcriptional regulator, LytTR family  42.74 
 
 
256 aa  95.1  1e-18  Spirosoma linguale DSM 74  Bacteria  normal  0.239231  normal 
 
 
-
 
NC_007355  Mbar_A2510  transcriptional regulator  42.06 
 
 
157 aa  94  2e-18  Methanosarcina barkeri str. Fusaro  Archaea  decreased coverage  0.000843612  normal  0.354799 
 
 
-
 
NC_007575  Suden_0616  two component transcriptional regulator  37.5 
 
 
249 aa  94  2e-18  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_1110  response regulator receiver and ANTAR domain protein  44.17 
 
 
197 aa  93.6  3e-18  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0520878  n/a   
 
 
-
 
NC_009523  RoseRS_2361  response regulator receiver/ANTAR domain-containing protein  43.33 
 
 
196 aa  93.6  3e-18  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_013132  Cpin_0115  two component, sigma54 specific, transcriptional regulator, Fis family  34.75 
 
 
481 aa  92.8  5e-18  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_2047  response regulator receiver and ANTAR domain protein  39.6 
 
 
191 aa  92  9e-18  Chloroflexus aggregans DSM 9485  Bacteria  unclonable  0.000000169009  normal 
 
 
-
 
NC_007955  Mbur_2294  response regulator receiver  41.82 
 
 
134 aa  91.7  1e-17  Methanococcoides burtonii DSM 6242  Archaea  normal  0.371138  n/a   
 
 
-
 
NC_013132  Cpin_0268  sigma54 specific transcriptional regulator, Fis family  36.6 
 
 
651 aa  90.9  2e-17  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_007519  Dde_1631  response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor  38.21 
 
 
561 aa  90.5  2e-17  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.608678  n/a   
 
 
-
 
NC_013132  Cpin_1348  two component, sigma54 specific, transcriptional regulator, Fis family  42.62 
 
 
461 aa  90.9  2e-17  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_013132  Cpin_4853  two component, sigma54 specific, transcriptional regulator, Fis family  37.19 
 
 
457 aa  90.5  2e-17  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.231814  hitchhiker  0.00735887 
 
 
-
 
NC_007575  Suden_1012  response regulator receiver domain-containing protein  42.86 
 
 
109 aa  90.1  3e-17  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_009712  Mboo_1517  response regulator receiver protein  40.5 
 
 
127 aa  89.7  5e-17  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.394491  normal  0.160821 
 
 
-
 
NC_007955  Mbur_0834  response regulator receiver  41.46 
 
 
134 aa  88.2  1e-16  Methanococcoides burtonii DSM 6242  Archaea  hitchhiker  0.000017528  n/a   
 
 
-
 
NC_013132  Cpin_4307  sigma54 specific transcriptional regulator, Fis family  35.17 
 
 
635 aa  88.2  1e-16  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.056389 
 
 
-
 
NC_009712  Mboo_0913  response regulator receiver protein  38.14 
 
 
124 aa  88.2  1e-16  Candidatus Methanoregula boonei 6A8  Archaea  normal  hitchhiker  0.0000000115879 
 
 
-
 
NC_011138  MADE_01100  sensory box/GGDEF family protein  39.06 
 
 
798 aa  87  2e-16  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_013037  Dfer_5458  putative two component, sigma54 specific, transcriptional regulator, Fis family  32.95 
 
 
582 aa  87.8  2e-16  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.336827 
 
 
-
 
NC_013037  Dfer_1630  two component transcriptional regulator, LytTR family  40.98 
 
 
243 aa  87  3e-16  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.192215 
 
 
-
 
NC_013037  Dfer_5460  sigma54 specific transcriptional regulator, Fis family  38.06 
 
 
650 aa  87  3e-16  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.665291  normal  0.225769 
 
 
-
 
NC_013132  Cpin_4365  two component, sigma54 specific, transcriptional regulator, Fis family  36.29 
 
 
471 aa  86.7  4e-16  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.231326 
 
 
-
 
NC_013159  Svir_25990  response regulator with putative antiterminator output domain protein  38.33 
 
 
204 aa  85.9  5e-16  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_013530  Xcel_1506  response regulator receiver and ANTAR domain protein  37.19 
 
 
220 aa  85.9  6e-16  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_3658  response regulator receiver/ANTAR domain-containing protein  37.93 
 
 
194 aa  85.5  8e-16  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.568485 
 
 
-
 
NC_013093  Amir_5540  response regulator receiver and ANTAR domain protein  39.5 
 
 
200 aa  84.3  0.000000000000002  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_4102  response regulator receiver/ANTAR domain-containing protein  41.18 
 
 
194 aa  84.3  0.000000000000002  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_007777  Francci3_1618  response regulator receiver/ANTAR domain-containing protein  38.66 
 
 
199 aa  84.3  0.000000000000002  Frankia sp. CcI3  Bacteria  normal  0.144201  normal  0.292856 
 
 
-
 
NC_009921  Franean1_2035  response regulator receiver/ANTAR domain-containing protein  36.97 
 
 
199 aa  84  0.000000000000002  Frankia sp. EAN1pec  Bacteria  normal  normal  0.480822 
 
 
-
 
NC_012669  Bcav_2208  response regulator receiver and ANTAR domain protein  35.83 
 
 
220 aa  83.6  0.000000000000003  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_009565  TBFG_11642  two component system transcriptional regulator  35.77 
 
 
205 aa  83.6  0.000000000000003  Mycobacterium tuberculosis F11  Bacteria  normal  0.0378541  normal  0.634495 
 
 
-
 
NC_013132  Cpin_6068  response regulator receiver protein  40.98 
 
 
248 aa  83.6  0.000000000000003  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_3671  Sigma 54 interacting domain protein  34.62 
 
 
657 aa  83.6  0.000000000000003  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
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