More than 300 homologs were found in PanDaTox collection
for query gene Cthe_0891 on replicon NC_009012
Organism: Clostridium thermocellum ATCC 27405



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009012  Cthe_0891  response regulator receiver protein  100 
 
 
147 aa  285  1e-76  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_0749  response regulator receiver protein  34.13 
 
 
406 aa  92  2e-18  Cyanothece sp. PCC 7425  Bacteria  normal  0.893418  normal  0.0890519 
 
 
-
 
NC_004116  SAG0123  DNA-binding response regulator  35.43 
 
 
223 aa  85.5  2e-16  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_008347  Mmar10_1277  response regulator receiver modulated diguanylate cyclase  32.58 
 
 
454 aa  85.5  2e-16  Maricaulis maris MCS10  Bacteria  normal  0.410696  normal  0.0388481 
 
 
-
 
NC_009972  Haur_0605  adenylate/guanylate cyclase  35 
 
 
355 aa  84.3  4e-16  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.657653  n/a   
 
 
-
 
NC_014148  Plim_2180  response regulator receiver  28.57 
 
 
151 aa  84.7  4e-16  Planctomyces limnophilus DSM 3776  Bacteria  normal  0.269305  n/a   
 
 
-
 
NC_013411  GYMC61_1696  two component transcriptional regulator, winged helix family  32.56 
 
 
224 aa  82.8  0.000000000000001  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011831  Cagg_1006  response regulator receiver modulated diguanylate cyclase  33.33 
 
 
312 aa  81.6  0.000000000000003  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_008312  Tery_3999  adenylate/guanylate cyclase  36.11 
 
 
351 aa  82  0.000000000000003  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.558191 
 
 
-
 
NC_007413  Ava_2150  response regulator receiver Signal transduction histidine kinase  36.59 
 
 
443 aa  81.3  0.000000000000004  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.394463 
 
 
-
 
NC_007519  Dde_1941  response regulator receiver sensor signal transduction histidine kinase  39.81 
 
 
395 aa  81.3  0.000000000000004  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.0596409  n/a   
 
 
-
 
NC_004578  PSPTO_4080  DNA-binding response regulator, LuxR family  31.85 
 
 
222 aa  80.5  0.000000000000007  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.542388  n/a   
 
 
-
 
NC_009654  Mmwyl1_1086  response regulator receiver modulated metal dependent phosphohydrolase  35.25 
 
 
331 aa  80.1  0.000000000000008  Marinomonas sp. MWYL1  Bacteria  normal  0.226857  hitchhiker  0.0000000112469 
 
 
-
 
NC_012918  GM21_2370  response regulator receiver sensor signal transduction histidine kinase  34.09 
 
 
414 aa  80.1  0.00000000000001  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_002939  GSU1038  sensory box histidine kinase/response regulator  29.08 
 
 
513 aa  78.6  0.00000000000002  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_1267  integral membrane sensor hybrid histidine kinase  37.93 
 
 
916 aa  78.6  0.00000000000002  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_007575  Suden_1924  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  35.86 
 
 
367 aa  79  0.00000000000002  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.620973  n/a   
 
 
-
 
NC_011830  Dhaf_1561  response regulator receiver modulated diguanylate cyclase  37.98 
 
 
455 aa  79.3  0.00000000000002  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.0000000734361  n/a   
 
 
-
 
NC_011831  Cagg_2467  response regulator receiver modulated serine phosphatase  31.29 
 
 
385 aa  79  0.00000000000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_3534  response regulator receiver protein  28.26 
 
 
393 aa  78.6  0.00000000000003  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_3274  response regulator receiver sensor signal transduction histidine kinase  35.29 
 
 
383 aa  78.2  0.00000000000004  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_01717  putative response regulator  35.33 
 
 
568 aa  77.8  0.00000000000004  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2891  response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal  38.46 
 
 
858 aa  78.2  0.00000000000004  Dechloromonas aromatica RCB  Bacteria  normal  normal  0.432629 
 
 
-
 
NC_007298  Daro_3005  response regulator receiver  34.92 
 
 
361 aa  77.8  0.00000000000004  Dechloromonas aromatica RCB  Bacteria  normal  0.931132  normal 
 
 
-
 
NC_012918  GM21_0975  response regulator receiver sensor signal transduction histidine kinase  35.29 
 
 
383 aa  77.8  0.00000000000005  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010002  Daci_3831  GAF sensor hybrid histidine kinase  36.36 
 
 
1177 aa  77.4  0.00000000000005  Delftia acidovorans SPH-1  Bacteria  normal  0.195944  normal  0.0220401 
 
 
-
 
NC_008639  Cpha266_1801  integral membrane sensor hybrid histidine kinase  36.04 
 
 
699 aa  77.8  0.00000000000005  Chlorobium phaeobacteroides DSM 266  Bacteria  unclonable  0.00000631548  n/a   
 
 
-
 
NC_009972  Haur_4908  response regulator receiver protein  33.64 
 
 
130 aa  76.6  0.0000000000001  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.00100675  n/a   
 
 
-
 
NC_013501  Rmar_0776  response regulator receiver protein  32.41 
 
 
121 aa  76.3  0.0000000000001  Rhodothermus marinus DSM 4252  Bacteria  normal  0.428997  n/a   
 
 
-
 
NC_008576  Mmc1_1834  CheA signal transduction histidine kinases  34.65 
 
 
878 aa  76.6  0.0000000000001  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_010581  Bind_1213  response regulator receiver modulated diguanylate cyclase  28.47 
 
 
457 aa  76.6  0.0000000000001  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_009457  VC0395_A0963  response regulator  38.46 
 
 
441 aa  75.5  0.0000000000002  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_1474  response regulator receiver modulated metal dependent phosphohydrolase  33.81 
 
 
345 aa  75.5  0.0000000000002  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_007354  Ecaj_0304  response regulator PleD  30.08 
 
 
458 aa  75.5  0.0000000000002  Ehrlichia canis str. Jake  Bacteria  normal  0.0864091  n/a   
 
 
-
 
NC_007643  Rru_A1398  response regulator receiver domain-containing protein  29.51 
 
 
123 aa  75.9  0.0000000000002  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.503734  n/a   
 
 
-
 
NC_007955  Mbur_2108  multisensor signal transduction histidine kinase  35.04 
 
 
492 aa  75.9  0.0000000000002  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_011004  Rpal_1441  two component transcriptional regulator, LuxR family  30.47 
 
 
308 aa  75.9  0.0000000000002  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_0298  response regulator receiver modulated metal dependent phosphohydrolase  32.17 
 
 
331 aa  75.5  0.0000000000002  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.7054  normal  0.177262 
 
 
-
 
NC_010571  Oter_0959  response regulator receiver sensor signal transduction histidine kinase  31.54 
 
 
372 aa  76.3  0.0000000000002  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_5086  response regulator receiver modulated diguanylate cyclase  42.31 
 
 
465 aa  75.9  0.0000000000002  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_010505  Mrad2831_0215  adenylate/guanylate cyclase  31.45 
 
 
351 aa  75.1  0.0000000000003  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.354021  normal 
 
 
-
 
NC_009675  Anae109_3404  two component, sigma54 specific, Fis family transcriptional regulator  34.31 
 
 
455 aa  74.7  0.0000000000003  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.235439  normal  0.675632 
 
 
-
 
NC_007799  ECH_0773  response regulator PleD  30.08 
 
 
458 aa  75.1  0.0000000000003  Ehrlichia chaffeensis str. Arkansas  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_1923  response regulator receiver domain-containing protein  36.43 
 
 
569 aa  75.1  0.0000000000003  Saccharophagus degradans 2-40  Bacteria  normal  0.285353  normal 
 
 
-
 
NC_008740  Maqu_3676  response regulator receiver modulated metal dependent phosphohydrolase  34.17 
 
 
328 aa  75.1  0.0000000000003  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_2159  two component transcriptional regulator, winged helix family  36.49 
 
 
227 aa  75.1  0.0000000000003  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00177162  n/a   
 
 
-
 
NC_011989  Avi_3499  transcriptional regulator LuxR family  28.66 
 
 
312 aa  75.1  0.0000000000003  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011666  Msil_0424  response regulator receiver modulated diguanylate cyclase  28.79 
 
 
469 aa  75.1  0.0000000000003  Methylocella silvestris BL2  Bacteria  n/a    normal  0.97349 
 
 
-
 
NC_008340  Mlg_0356  response regulator receiver protein  36.13 
 
 
121 aa  75.1  0.0000000000003  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.0780111  normal  0.957515 
 
 
-
 
NC_011138  MADE_01756  Response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase)  31.43 
 
 
337 aa  74.7  0.0000000000004  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.844049  n/a   
 
 
-
 
NC_008576  Mmc1_3165  response regulator receiver modulated metal dependent phosphohydrolase  32.87 
 
 
367 aa  74.3  0.0000000000004  Magnetococcus sp. MC-1  Bacteria  normal  0.0569095  normal  0.0154692 
 
 
-
 
NC_011830  Dhaf_1567  signal transduction histidine kinase, LytS  36.11 
 
 
1016 aa  74.7  0.0000000000004  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0336431  n/a   
 
 
-
 
NC_008782  Ajs_0647  multi-sensor hybrid histidine kinase  37.1 
 
 
1137 aa  74.3  0.0000000000005  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_2712  response regulator receiver sensor signal transduction histidine kinase  30.89 
 
 
414 aa  74.3  0.0000000000005  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_2841  response regulator receiver modulated GAF sensor protein  30.77 
 
 
308 aa  74.3  0.0000000000005  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.585847 
 
 
-
 
NC_013730  Slin_1031  GAF sensor hybrid histidine kinase  34.82 
 
 
1131 aa  74.3  0.0000000000005  Spirosoma linguale DSM 74  Bacteria  normal  0.768055  normal 
 
 
-
 
NC_008709  Ping_0978  response regulator receiver modulated diguanylate cyclase  36.15 
 
 
322 aa  74.3  0.0000000000005  Psychromonas ingrahamii 37  Bacteria  normal  0.97362  decreased coverage  0.00116316 
 
 
-
 
NC_011992  Dtpsy_0626  histidine kinase  37.1 
 
 
1137 aa  74.3  0.0000000000005  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_008554  Sfum_2304  multi-sensor hybrid histidine kinase  33.33 
 
 
870 aa  74.3  0.0000000000005  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_0702  response regulator receiver modulated metal dependent phosphohydrolase  29.37 
 
 
331 aa  74.3  0.0000000000006  Roseiflexus sp. RS-1  Bacteria  normal  0.140022  normal 
 
 
-
 
NC_007298  Daro_3553  response regulator receiver  34.72 
 
 
384 aa  73.9  0.0000000000006  Dechloromonas aromatica RCB  Bacteria  normal  0.739627  normal 
 
 
-
 
NC_007413  Ava_1030  response regulator receiver modulated diguanylate cyclase  28.26 
 
 
330 aa  74.3  0.0000000000006  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.33399 
 
 
-
 
NC_013501  Rmar_2360  response regulator receiver protein  30.19 
 
 
523 aa  73.9  0.0000000000006  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_007493  RSP_2443  putative chemotaxis response regulator, CheY5  31.15 
 
 
122 aa  74.3  0.0000000000006  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.451762  n/a   
 
 
-
 
NC_009049  Rsph17029_1107  response regulator receiver protein  31.15 
 
 
122 aa  74.3  0.0000000000006  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.91502 
 
 
-
 
NC_012560  Avin_25160  response regulator  33.06 
 
 
356 aa  73.9  0.0000000000006  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_2145  multi-sensor hybrid histidine kinase  35.71 
 
 
1271 aa  73.9  0.0000000000007  Desulfotomaculum reducens MI-1  Bacteria  normal  0.152151  n/a   
 
 
-
 
NC_007498  Pcar_1055  two component signal transduction response regulator  30.77 
 
 
734 aa  73.9  0.0000000000007  Pelobacter carbinolicus DSM 2380  Bacteria  normal  0.0148851  n/a   
 
 
-
 
NC_011884  Cyan7425_2205  multi-sensor hybrid histidine kinase  29.37 
 
 
887 aa  73.9  0.0000000000007  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.188088 
 
 
-
 
NC_013165  Shel_23040  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  34.45 
 
 
229 aa  73.6  0.0000000000008  Slackia heliotrinireducens DSM 20476  Bacteria  normal  0.318653  normal 
 
 
-
 
NC_007484  Noc_1271  hybrid signal transduction histidine kinase and diguanylate cyclase/phosphodiesterase  30.61 
 
 
1499 aa  73.9  0.0000000000008  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.422796  n/a   
 
 
-
 
NC_011726  PCC8801_1475  response regulator receiver modulated GAF sensor protein  30.3 
 
 
311 aa  73.6  0.0000000000008  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_1502  response regulator receiver modulated GAF sensor protein  30.3 
 
 
311 aa  73.6  0.0000000000008  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_009636  Smed_0926  response regulator PleD  29.55 
 
 
455 aa  73.6  0.0000000000008  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.773886 
 
 
-
 
NC_009012  Cthe_0287  GAF sensor hybrid histidine kinase  38.1 
 
 
1160 aa  73.6  0.0000000000009  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_6679  response regulator receiver modulated diguanylate cyclase  28.68 
 
 
457 aa  72.8  0.000000000001  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_011312  VSAL_I2575  chitin degradation sensor protein  29.58 
 
 
1127 aa  73.2  0.000000000001  Aliivibrio salmonicida LFI1238  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_0981  two component transcriptional regulator, LuxR family  31.43 
 
 
221 aa  72.8  0.000000000001  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.416641 
 
 
-
 
NC_008009  Acid345_4060  response regulator receiver modulated metal dependent phosphohydrolase  35.43 
 
 
365 aa  73.2  0.000000000001  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal  0.0748941 
 
 
-
 
NC_010506  Swoo_1513  response regulator receiver modulated diguanylate cyclase  37.14 
 
 
301 aa  73.2  0.000000000001  Shewanella woodyi ATCC 51908  Bacteria  normal  normal  0.0153071 
 
 
-
 
NC_010002  Daci_0218  two component LuxR family transcriptional regulator  31.11 
 
 
339 aa  73.2  0.000000000001  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_009668  Oant_3677  response regulator PleD  32.35 
 
 
461 aa  72.8  0.000000000001  Ochrobactrum anthropi ATCC 49188  Bacteria  decreased coverage  0.00345303  n/a   
 
 
-
 
NC_013132  Cpin_5566  GAF sensor hybrid histidine kinase  31.62 
 
 
1203 aa  73.2  0.000000000001  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.0247633 
 
 
-
 
NC_008709  Ping_3719  sensor histidine kinase  36.21 
 
 
1278 aa  72.8  0.000000000002  Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_002978  WD0221  response regulator PleD  31.3 
 
 
460 aa  72  0.000000000002  Wolbachia endosymbiont of Drosophila melanogaster  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_3541  response regulator PleD  28.79 
 
 
457 aa  72.4  0.000000000002  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_009719  Plav_2815  response regulator receiver modulated diguanylate cyclase  28.79 
 
 
457 aa  72  0.000000000002  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.631579  normal  0.0857187 
 
 
-
 
NC_009012  Cthe_1805  response regulator receiver modulated diguanylate cyclase  32.5 
 
 
310 aa  72  0.000000000002  Clostridium thermocellum ATCC 27405  Bacteria  normal  0.0638722  n/a   
 
 
-
 
NC_013440  Hoch_2175  response regulator receiver sensor signal transduction histidine kinase  31.75 
 
 
395 aa  72.4  0.000000000002  Haliangium ochraceum DSM 14365  Bacteria  normal  0.924768  normal  0.400775 
 
 
-
 
NC_007519  Dde_1942  metal dependent phosphohydrolase  32.35 
 
 
363 aa  72.4  0.000000000002  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.284574  n/a   
 
 
-
 
NC_009831  Ssed_2316  response regulator receiver protein  38.1 
 
 
226 aa  72.4  0.000000000002  Shewanella sediminis HAW-EB3  Bacteria  decreased coverage  0.00000147543  hitchhiker  0.000888492 
 
 
-
 
NC_009783  VIBHAR_03091  hypothetical protein  33.03 
 
 
368 aa  72.4  0.000000000002  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_013037  Dfer_0393  histidine kinase  33.33 
 
 
1200 aa  72.8  0.000000000002  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.564913 
 
 
-
 
NC_013440  Hoch_5143  response regulator receiver sensor signal transduction histidine kinase  30.94 
 
 
408 aa  72.4  0.000000000002  Haliangium ochraceum DSM 14365  Bacteria  normal  0.19932  normal 
 
 
-
 
NC_007796  Mhun_2690  response regulator receiver domain-containing protein  34.92 
 
 
124 aa  72.4  0.000000000002  Methanospirillum hungatei JF-1  Archaea  normal  normal  0.0818688 
 
 
-
 
NC_008825  Mpe_A0671  two component LuxR family transcriptional regulator  29.1 
 
 
333 aa  72.8  0.000000000002  Methylibium petroleiphilum PM1  Bacteria  normal  0.0205263  normal 
 
 
-
 
NC_011146  Gbem_0799  response regulator receiver protein  32.81 
 
 
225 aa  72  0.000000000002  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_010338  Caul_0611  response regulator receiver protein  33.64 
 
 
121 aa  72.8  0.000000000002  Caulobacter sp. K31  Bacteria  normal  normal 
 
 
-
 
NC_009428  Rsph17025_1787  response regulator receiver protein  31.15 
 
 
122 aa  72.4  0.000000000002  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_1710  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  28.93 
 
 
720 aa  72.4  0.000000000002  Magnetococcus sp. MC-1  Bacteria  normal  0.425295  normal 
 
 
-
 
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