More than 300 homologs were found in PanDaTox collection
for query gene Sfum_2498 on replicon NC_008554
Organism: Syntrophobacter fumaroxidans MPOB



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_008554  Sfum_2498  hypothetical protein  100 
 
 
380 aa  759    Syntrophobacter fumaroxidans MPOB  Bacteria  decreased coverage  0.00553555  normal 
 
 
-
 
NC_007520  Tcr_0434  hypothetical protein  31.85 
 
 
425 aa  205  9e-52  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_2374  ABC-type transport system, permease component  30.62 
 
 
409 aa  181  2e-44  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.000200206  n/a   
 
 
-
 
NC_012849  Rpic12D_5303  protein of unknown function DUF214  29.86 
 
 
830 aa  163  5.0000000000000005e-39  Ralstonia pickettii 12D  Bacteria  normal  normal 
 
 
-
 
NC_013457  VEA_001465  ABC-type transport system involved in lipoprotein release permease component  28.42 
 
 
411 aa  154  2e-36  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_009831  Ssed_3197  hypothetical protein  28.16 
 
 
427 aa  147  2.0000000000000003e-34  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_009784  VIBHAR_05401  hypothetical protein  29.31 
 
 
409 aa  147  3e-34  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_009784  VIBHAR_05402  hypothetical protein  27.73 
 
 
411 aa  146  5e-34  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_003910  CPS_5041  putative ABC transporter, permease protein  27.86 
 
 
441 aa  145  1e-33  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_2373  ABC-type transport system, permease component  30.77 
 
 
407 aa  143  4e-33  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.000351897  n/a   
 
 
-
 
NC_013501  Rmar_2534  protein of unknown function DUF214  29.14 
 
 
406 aa  143  4e-33  Rhodothermus marinus DSM 4252  Bacteria  normal  0.261611  n/a   
 
 
-
 
NC_013457  VEA_001464  ABC-type transport system involved in lipoprotein release permease component  28.12 
 
 
409 aa  142  9.999999999999999e-33  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_009831  Ssed_3196  hypothetical protein  27.15 
 
 
410 aa  142  9.999999999999999e-33  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1663  protein of unknown function DUF214  30.81 
 
 
535 aa  132  1.0000000000000001e-29  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1691  protein of unknown function DUF214  31.64 
 
 
295 aa  130  5.0000000000000004e-29  Ralstonia pickettii 12J  Bacteria  normal  0.132145  normal 
 
 
-
 
NC_010506  Swoo_1429  hypothetical protein  29.25 
 
 
411 aa  130  6e-29  Shewanella woodyi ATCC 51908  Bacteria  normal  normal 
 
 
-
 
NC_009092  Shew_2660  hypothetical protein  28.69 
 
 
410 aa  129  1.0000000000000001e-28  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_009092  Shew_2659  hypothetical protein  30.16 
 
 
421 aa  127  2.0000000000000002e-28  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_013501  Rmar_2535  protein of unknown function DUF214  30.48 
 
 
412 aa  127  4.0000000000000003e-28  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_010506  Swoo_1430  hypothetical protein  26.58 
 
 
428 aa  124  4e-27  Shewanella woodyi ATCC 51908  Bacteria  normal  normal 
 
 
-
 
NC_003910  CPS_5042  ABC transporter, permease protein, putative  26.71 
 
 
415 aa  123  7e-27  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_007520  Tcr_0435  hypothetical protein  27.89 
 
 
431 aa  111  2.0000000000000002e-23  Thiomicrospira crunogena XCL-2  Bacteria  normal  0.131989  n/a   
 
 
-
 
NC_007509  Bcep18194_C7413  ABC efflux pump, inner membrane subunit  27.64 
 
 
405 aa  103  6e-21  Burkholderia sp. 383  Bacteria  normal  0.155043  normal 
 
 
-
 
NC_009483  Gura_2438  hypothetical protein  28.87 
 
 
406 aa  101  2e-20  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_1621  protein of unknown function DUF214  26.44 
 
 
404 aa  100  3e-20  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_009484  Acry_0940  LolC/E family lipoprotein releasing system, transmembrane protein  22.8 
 
 
415 aa  97.1  4e-19  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2395  hypothetical protein  25.14 
 
 
404 aa  95.9  1e-18  Dechloromonas aromatica RCB  Bacteria  normal  0.111806  normal  0.574816 
 
 
-
 
NC_008786  Veis_2542  hypothetical protein  25.21 
 
 
441 aa  95.5  1e-18  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.429279  normal  0.740963 
 
 
-
 
NC_010814  Glov_1801  protein of unknown function DUF214  23.77 
 
 
412 aa  95.5  1e-18  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007643  Rru_A1578  LolC/E family lipoprotein releasing system, transmembrane protein  25.23 
 
 
417 aa  94.7  2e-18  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.0665062  n/a   
 
 
-
 
NC_009720  Xaut_4462  LolC/E family lipoprotein releasing system, transmembrane protein  25.21 
 
 
447 aa  94  4e-18  Xanthobacter autotrophicus Py2  Bacteria  normal  0.919983  normal  0.365763 
 
 
-
 
NC_008554  Sfum_2497  hypothetical protein  25.98 
 
 
422 aa  93.2  6e-18  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.536779  normal 
 
 
-
 
NC_007614  Nmul_A0369  hypothetical protein  24.62 
 
 
403 aa  93.2  7e-18  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_013946  Mrub_2901  hypothetical protein  27.84 
 
 
411 aa  92.8  1e-17  Meiothermus ruber DSM 1279  Bacteria  normal  normal  0.0934048 
 
 
-
 
NC_011891  A2cp1_3560  protein of unknown function DUF214  26.2 
 
 
405 aa  88.6  2e-16  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_007958  RPD_2864  LolC/E family lipoprotein releasing system, transmembrane protein  24.06 
 
 
422 aa  88.6  2e-16  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.998701  normal  0.300269 
 
 
-
 
NC_011353  ECH74115_1293  efflux ABC transporter, permease protein  25.63 
 
 
436 aa  88.2  2e-16  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  normal  0.353692 
 
 
-
 
NC_010172  Mext_1065  LolC/E family lipoprotein releasing system, transmembrane protein  25.72 
 
 
439 aa  88.6  2e-16  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.123078 
 
 
-
 
NC_011899  Hore_19660  ABC-type transport system, involved in lipoprotein release, permease component  23.85 
 
 
400 aa  87.4  4e-16  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_0889  LolC/E family lipoprotein releasing system, transmembrane protein  24.72 
 
 
411 aa  87.4  4e-16  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_007760  Adeh_3411  ABC transporter, inner membrane subunit  25.84 
 
 
405 aa  86.3  9e-16  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.108471  n/a   
 
 
-
 
NC_011004  Rpal_3275  lipoprotein releasing system, transmembrane protein, LolC/E family  23.48 
 
 
422 aa  85.9  0.000000000000001  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.314483  n/a   
 
 
-
 
NC_011757  Mchl_1195  lipoprotein releasing system, transmembrane protein, LolC/E family  25.43 
 
 
439 aa  85.9  0.000000000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_009901  Spea_1547  LolC/E family lipoprotein releasing system, transmembrane protein  26.57 
 
 
417 aa  84.7  0.000000000000002  Shewanella pealeana ATCC 700345  Bacteria  normal  0.124688  n/a   
 
 
-
 
NC_010725  Mpop_1000  lipoprotein releasing system, transmembrane protein, LolC/E family  25.15 
 
 
439 aa  85.1  0.000000000000002  Methylobacterium populi BJ001  Bacteria  normal  normal  0.14096 
 
 
-
 
NC_013173  Dbac_3383  lipoprotein releasing system, transmembrane protein, LolC/E family  24.21 
 
 
409 aa  84  0.000000000000004  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_23230  ABC-type transport system, involved in lipoprotein release, permease component  23.14 
 
 
419 aa  84  0.000000000000004  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000130781  n/a   
 
 
-
 
NC_009719  Plav_3204  LolC/E family lipoprotein releasing system, transmembrane protein  24.79 
 
 
427 aa  84  0.000000000000004  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.22882  normal 
 
 
-
 
NC_007778  RPB_2598  LolC/E family lipoprotein releasing system, transmembrane protein  23.23 
 
 
426 aa  84  0.000000000000004  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.258492  normal  0.437082 
 
 
-
 
NC_009092  Shew_1634  LolC/E family lipoprotein releasing system, transmembrane protein  24.93 
 
 
417 aa  84.3  0.000000000000004  Shewanella loihica PV-4  Bacteria  normal  0.0870078  normal  0.876319 
 
 
-
 
NC_008639  Cpha266_1098  hypothetical protein  25.28 
 
 
429 aa  83.2  0.000000000000008  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  0.0142755  n/a   
 
 
-
 
NC_013422  Hneap_0224  lipoprotein releasing system, transmembrane protein, LolC/E family  25.76 
 
 
415 aa  82.4  0.00000000000001  Halothiobacillus neapolitanus c2  Bacteria  normal  0.0374875  n/a   
 
 
-
 
NC_010505  Mrad2831_2040  LolC/E family lipoprotein releasing system, transmembrane protein  24.36 
 
 
436 aa  82.4  0.00000000000001  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.489126  normal 
 
 
-
 
NC_010511  M446_4409  LolC/E family lipoprotein releasing system, transmembrane protein  25.3 
 
 
433 aa  81.6  0.00000000000002  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.452061 
 
 
-
 
NC_013946  Mrub_2903  hypothetical protein  25.53 
 
 
410 aa  81.3  0.00000000000002  Meiothermus ruber DSM 1279  Bacteria  normal  normal  0.110934 
 
 
-
 
NC_009524  PsycPRwf_1740  LolC/E family lipoprotein releasing system, transmembrane protein  26.37 
 
 
411 aa  81.6  0.00000000000002  Psychrobacter sp. PRwf-1  Bacteria  normal  normal  0.170655 
 
 
-
 
NC_012918  GM21_3423  lipoprotein releasing system, transmembrane protein, LolC/E family  27.65 
 
 
416 aa  80.9  0.00000000000003  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011666  Msil_0700  lipoprotein releasing system, transmembrane protein, LolC/E family  25.54 
 
 
423 aa  81.3  0.00000000000003  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_013457  VEA_000978  ABC-type transport system involved in lipoprotein release permease component  24.08 
 
 
422 aa  81.3  0.00000000000003  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_2259  lipoprotein releasing system transmembrane protein LolC, putative  27.21 
 
 
416 aa  80.9  0.00000000000004  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_009784  VIBHAR_07028  efflux ABC transporter ATP-binding/permease  23.35 
 
 
422 aa  80.9  0.00000000000004  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_012850  Rleg_1372  lipoprotein releasing system, transmembrane protein, LolC/E family  23.31 
 
 
434 aa  80.5  0.00000000000004  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_011369  Rleg2_1280  lipoprotein releasing system, transmembrane protein, LolC/E family  24.01 
 
 
434 aa  80.5  0.00000000000005  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.0107812  normal  0.317103 
 
 
-
 
NC_009783  VIBHAR_01530  hypothetical protein  26.87 
 
 
374 aa  80.1  0.00000000000005  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_007925  RPC_2428  LolC/E family lipoprotein releasing system, transmembrane protein  23.48 
 
 
426 aa  80.1  0.00000000000006  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.507047  normal  0.0670699 
 
 
-
 
NC_007951  Bxe_A1566  ABC lipoprotein efflux pump, inner membrane subunit  24.51 
 
 
417 aa  80.1  0.00000000000006  Burkholderia xenovorans LB400  Bacteria  normal  0.764315  normal  0.414868 
 
 
-
 
NC_009831  Ssed_2829  LolC/E family lipoprotein releasing system, transmembrane protein  26.1 
 
 
419 aa  80.1  0.00000000000006  Shewanella sediminis HAW-EB3  Bacteria  normal  0.417689  normal  0.0183937 
 
 
-
 
NC_008544  Bcen2424_6004  hypothetical protein  26.15 
 
 
405 aa  80.1  0.00000000000006  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_010681  Bphyt_2567  lipoprotein releasing system, transmembrane protein, LolC/E family  24.51 
 
 
417 aa  79.7  0.00000000000007  Burkholderia phytofirmans PsJN  Bacteria  normal  0.178921  normal  0.0571791 
 
 
-
 
NC_011989  Avi_1740  ABC transporter membrane spanning protein  23.2 
 
 
435 aa  79.7  0.00000000000008  Agrobacterium vitis S4  Bacteria  normal  0.147499  n/a   
 
 
-
 
NC_010581  Bind_1796  LolC/E family lipoprotein releasing system, transmembrane protein  25.31 
 
 
439 aa  79.7  0.00000000000008  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.401704  normal 
 
 
-
 
NC_008062  Bcen_5639  hypothetical protein  26.15 
 
 
387 aa  79.7  0.00000000000009  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_008577  Shewana3_2285  LolC/E family lipoprotein releasing system, transmembrane protein  28.09 
 
 
416 aa  79.3  0.0000000000001  Shewanella sp. ANA-3  Bacteria  normal  0.0114014  normal 
 
 
-
 
NC_010622  Bphy_1446  LolC/E family lipoprotein releasing system, transmembrane protein  24.51 
 
 
417 aa  79  0.0000000000001  Burkholderia phymatum STM815  Bacteria  normal  0.644445  normal 
 
 
-
 
NC_013223  Dret_2233  lipoprotein releasing system, transmembrane protein, LolC/E family  24.58 
 
 
409 aa  78.6  0.0000000000002  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_007519  Dde_1366  LolC/E family lipoprotein releasing system, transmembrane protein  23.24 
 
 
408 aa  78.2  0.0000000000002  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.217764  n/a   
 
 
-
 
NC_010814  Glov_0758  lipoprotein releasing system, transmembrane protein, LolC/E family  24.59 
 
 
420 aa  78.6  0.0000000000002  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.00020569  n/a   
 
 
-
 
NC_011899  Hore_23240  ABC-type transport system, involved in lipoprotein release, permease component  21.77 
 
 
415 aa  78.2  0.0000000000002  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_008322  Shewmr7_1814  LolC/E family lipoprotein releasing system, transmembrane protein  27.72 
 
 
416 aa  78.6  0.0000000000002  Shewanella sp. MR-7  Bacteria  normal  0.109352  normal 
 
 
-
 
NC_008786  Veis_2530  hypothetical protein  23.74 
 
 
407 aa  78.2  0.0000000000002  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.0995274  normal 
 
 
-
 
NC_008321  Shewmr4_1734  LolC/E family lipoprotein releasing system, transmembrane protein  27.44 
 
 
416 aa  77.8  0.0000000000003  Shewanella sp. MR-4  Bacteria  hitchhiker  0.00172788  normal  0.754695 
 
 
-
 
NC_011883  Ddes_0613  lipoprotein releasing system, transmembrane protein, LolC/E family  25.28 
 
 
411 aa  77.4  0.0000000000004  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  unclonable  0.00000287642  n/a   
 
 
-
 
NC_007964  Nham_2196  LolC/E family lipoprotein releasing system, transmembrane protein  22.26 
 
 
426 aa  77  0.0000000000005  Nitrobacter hamburgensis X14  Bacteria  decreased coverage  0.00714902  n/a   
 
 
-
 
NC_007204  Psyc_0781  ABC lipoprotein exporter, inner membrane subunit, LolE  26.23 
 
 
411 aa  76.6  0.0000000000006  Psychrobacter arcticus 273-4  Bacteria  hitchhiker  0.000206341  normal 
 
 
-
 
NC_007355  Mbar_A3445  hypothetical protein  24.5 
 
 
389 aa  76.6  0.0000000000006  Methanosarcina barkeri str. Fusaro  Archaea  hitchhiker  0.000000235465  normal  0.187048 
 
 
-
 
NC_008740  Maqu_1747  LolC/E family lipoprotein releasing system, transmembrane protein  25.5 
 
 
414 aa  76.6  0.0000000000007  Marinobacter aquaeolei VT8  Bacteria  normal  0.726619  n/a   
 
 
-
 
NC_008553  Mthe_0918  hypothetical protein  23.19 
 
 
389 aa  76.6  0.0000000000007  Methanosaeta thermophila PT  Archaea  normal  n/a   
 
 
-
 
NC_007954  Sden_1678  LolC/E family lipoprotein releasing system, transmembrane protein  27.34 
 
 
421 aa  76.3  0.0000000000009  Shewanella denitrificans OS217  Bacteria  normal  0.0156822  n/a   
 
 
-
 
NC_004578  PSPTO_2111  lipoprotein releasing system transmembrane protein LolE  25.36 
 
 
427 aa  75.5  0.000000000001  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.386264  n/a   
 
 
-
 
NC_007404  Tbd_1761  LolC/E family lipoprotein releasing system, transmembrane protein  30.27 
 
 
414 aa  75.5  0.000000000001  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  0.293206  normal 
 
 
-
 
NC_009485  BBta_4040  putative lipoprotein-releasing system transmembrane protein (lolC)  23.73 
 
 
411 aa  75.9  0.000000000001  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.0498435 
 
 
-
 
NC_008347  Mmar10_1376  LolC/E family lipoprotein releasing system, transmembrane protein  24.86 
 
 
443 aa  75.9  0.000000000001  Maricaulis maris MCS10  Bacteria  normal  0.0730301  normal  0.0697431 
 
 
-
 
NC_009485  BBta_4530  LolC/E family lipoprotein releasing system, transmembrane protein  22.07 
 
 
426 aa  75.9  0.000000000001  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.947625  normal 
 
 
-
 
NC_007406  Nwi_1864  LolC/E family lipoprotein releasing system, transmembrane protein  21.65 
 
 
426 aa  74.7  0.000000000002  Nitrobacter winogradskyi Nb-255  Bacteria  normal  0.172929  normal  0.0361846 
 
 
-
 
NC_011146  Gbem_0837  lipoprotein releasing system, transmembrane protein, LolC/E family  26.76 
 
 
416 aa  75.1  0.000000000002  Geobacter bemidjiensis Bem  Bacteria  normal  0.0822431  n/a   
 
 
-
 
NC_007509  Bcep18194_C6689  hypothetical protein  28.81 
 
 
465 aa  74.7  0.000000000002  Burkholderia sp. 383  Bacteria  normal  0.874754  normal  0.836623 
 
 
-
 
NC_007520  Tcr_1172  LolC/E family lipoprotein releasing system, transmembrane protein  25.63 
 
 
416 aa  75.1  0.000000000002  Thiomicrospira crunogena XCL-2  Bacteria  normal  0.0830739  n/a   
 
 
-
 
NC_008709  Ping_2203  lipoprotein releasing system, transmembrane protein, LolC/E family protein  24.9 
 
 
408 aa  75.1  0.000000000002  Psychromonas ingrahamii 37  Bacteria  normal  normal  0.173685 
 
 
-
 
NC_008254  Meso_1041  LolC/E family lipoprotein releasing system, transmembrane protein  22.41 
 
 
427 aa  75.1  0.000000000002  Chelativorans sp. BNC1  Bacteria  normal  0.0901467  n/a   
 
 
-
 
NC_011894  Mnod_4145  lipoprotein releasing system, transmembrane protein, LolC/E family  24.06 
 
 
428 aa  73.9  0.000000000004  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
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