More than 300 homologs were found in PanDaTox collection
for query gene Vapar_4238 on replicon NC_012791
Organism: Variovorax paradoxus S110



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_012791  Vapar_4238  two component transcriptional regulator, LuxR family  100 
 
 		 356 aa  716    Variovorax paradoxus S110  Bacteria  normal  1  n/a   
 
 
-
 
NC_008781  Pnap_0979  response regulator receiver protein  72.02 
 
 		 336 aa  492  9.999999999999999e-139  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007948  Bpro_1354  two component LuxR family transcriptional regulator  71.35 
 
 		 349 aa  473  1e-132  Polaromonas sp. JS666  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008752  Aave_3524  two component LuxR family transcriptional regulator  67.91 
 
 		 353 aa  451  1.0000000000000001e-126  Acidovorax citrulli AAC00-1  Bacteria  normal  0.406085  normal  0.428998 
 
 
-
 
NC_007908  Rfer_3397  two component LuxR family transcriptional regulator  68.62 
 
 		 328 aa  434  1e-121  Rhodoferax ferrireducens T118  Bacteria  normal  1  n/a   
 
 
-
 
NC_008786  Veis_1731  response regulator receiver protein  64.53 
 
 		 361 aa  412  1e-114  Verminephrobacter eiseniae EF01-2  Bacteria  normal  1  normal  0.319975 
 
 
-
 
NC_008825  Mpe_A0671  two component LuxR family transcriptional regulator  57.06 
 
 		 333 aa  365  1e-100  Methylibium petroleiphilum PM1  Bacteria  normal  0.0205263  normal  1 
 
 
-
 
NC_010524  Lcho_1083  two component LuxR family transcriptional regulator  57.6 
 
 		 316 aa  353  2e-96  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  1 
 
 
-
 
NC_007298  Daro_1445  two component LuxR family transcriptional regulator  56.29 
 
 		 308 aa  332  5e-90  Dechloromonas aromatica RCB  Bacteria  normal  0.446624  normal  1 
 
 
-
 
NC_007947  Mfla_1761  two component LuxR family transcriptional regulator  52.06 
 
 		 311 aa  318  7e-86  Methylobacillus flagellatus KT  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009620  Smed_4179  response regulator receiver protein  43.81 
 
 		 309 aa  233  4.0000000000000004e-60  Sinorhizobium medicae WSM419  Bacteria  normal  1  normal  0.15819 
 
 
-
 
NC_010511  M446_0591  two component LuxR family transcriptional regulator  43.37 
 
 		 301 aa  231  1e-59  Methylobacterium sp. 4-46  Bacteria  normal  0.477799  hitchhiker  0.00469436 
 
 
-
 
NC_007952  Bxe_B1713  two component LuxR family transcriptional regulator  41.07 
 
 		 361 aa  230  2e-59  Burkholderia xenovorans LB400  Bacteria  normal  0.310925  normal  1 
 
 
-
 
NC_010725  Mpop_3574  two component transcriptional regulator, LuxR family  42.06 
 
 		 301 aa  230  3e-59  Methylobacterium populi BJ001  Bacteria  normal  0.0249095  normal  1 
 
 
-
 
NC_009485  BBta_0652  two component LuxR family transcriptional regulator  42.77 
 
 		 305 aa  229  6e-59  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.0800453  normal  0.813173 
 
 
-
 
NC_013422  Hneap_1587  two component transcriptional regulator, LuxR family  41.64 
 
 		 292 aa  229  7e-59  Halothiobacillus neapolitanus c2  Bacteria  normal  0.522901  n/a   
 
 
-
 
NC_011369  Rleg2_3066  two component transcriptional regulator, LuxR family  43.36 
 
 		 305 aa  226  4e-58  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011757  Mchl_3692  two component transcriptional regulator, LuxR family  40.65 
 
 		 300 aa  221  9.999999999999999e-57  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.170876  normal  1 
 
 
-
 
NC_010581  Bind_0974  two component LuxR family transcriptional regulator  41.25 
 
 		 309 aa  221  9.999999999999999e-57  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.883175  normal  0.426964 
 
 
-
 
NC_010172  Mext_3383  response regulator receiver  40.36 
 
 		 300 aa  221  1.9999999999999999e-56  Methylobacterium extorquens PA1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009654  Mmwyl1_0962  response regulator receiver protein  40.96 
 
 		 304 aa  219  5e-56  Marinomonas sp. MWYL1  Bacteria  normal  0.512477  normal  1 
 
 
-
 
NC_007958  RPD_3866  response regulator receiver  41.54 
 
 		 309 aa  218  8.999999999999998e-56  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.370865  normal  1 
 
 
-
 
NC_012850  Rleg_3321  two component transcriptional regulator, LuxR family  42.39 
 
 		 305 aa  218  1e-55  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  1  normal  0.536368 
 
 
-
 
NC_011989  Avi_3499  transcriptional regulator LuxR family  40.98 
 
 		 312 aa  216  5.9999999999999996e-55  Agrobacterium vitis S4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011004  Rpal_1441  two component transcriptional regulator, LuxR family  41.1 
 
 		 308 aa  214  9.999999999999999e-55  Rhodopseudomonas palustris TIE-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_007778  RPB_1250  two component LuxR family transcriptional regulator  40.74 
 
 		 309 aa  213  3.9999999999999995e-54  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.886948  normal  1 
 
 
-
 
NC_010515  Bcenmc03_5666  two component LuxR family transcriptional regulator  39.83 
 
 		 312 aa  211  1e-53  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.917296 
 
 
-
 
NC_008061  Bcen_3730  two component LuxR family transcriptional regulator  39.83 
 
 		 312 aa  211  1e-53  Burkholderia cenocepacia AU 1054  Bacteria  normal  1  n/a   
 
 
-
 
NC_008543  Bcen2424_4638  two component LuxR family transcriptional regulator  39.83 
 
 		 312 aa  211  1e-53  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008825  Mpe_A3585  two component LuxR family transcriptional regulator  40.62 
 
 		 306 aa  211  2e-53  Methylibium petroleiphilum PM1  Bacteria  normal  0.295986  normal  1 
 
 
-
 
NC_011666  Msil_2002  two component transcriptional regulator, LuxR family  40.36 
 
 		 306 aa  209  7e-53  Methylocella silvestris BL2  Bacteria  n/a    normal  1 
 
 
-
 
NC_007912  Sde_2977  response regulator receiver domain-containing protein  37.83 
 
 		 303 aa  209  7e-53  Saccharophagus degradans 2-40  Bacteria  normal  1  normal  0.13601 
 
 
-
 
NC_010505  Mrad2831_5514  two component LuxR family transcriptional regulator  41.12 
 
 		 305 aa  207  2e-52  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  1  normal  0.211273 
 
 
-
 
NC_008740  Maqu_3869  response regulator receiver protein  39.82 
 
 		 301 aa  206  6e-52  Marinobacter aquaeolei VT8  Bacteria  normal  1  n/a   
 
 
-
 
NC_010002  Daci_0218  two component LuxR family transcriptional regulator  38.66 
 
 		 339 aa  201  1.9999999999999998e-50  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011138  MADE_00878  two-component response regulator  35.36 
 
 		 298 aa  200  3e-50  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_007948  Bpro_0562  two component LuxR family transcriptional regulator  38.65 
 
 		 297 aa  199  6e-50  Polaromonas sp. JS666  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008709  Ping_2984  two component transcriptional regulator, LuxR family protein  38.14 
 
 		 295 aa  194  1e-48  Psychromonas ingrahamii 37  Bacteria  normal  0.43543  normal  0.546259 
 
 
-
 
NC_007794  Saro_1665  two component LuxR family transcriptional regulator  40.31 
 
 		 307 aa  194  1e-48  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  1  n/a   
 
 
-
 
NC_010571  Oter_1720  two component LuxR family transcriptional regulator  36.83 
 
 		 301 aa  177  3e-43  Opitutus terrae PB90-1  Bacteria  normal  0.162572  normal  0.616267 
 
 
-
 
NC_012791  Vapar_3147  two component transcriptional regulator, LuxR family  50.63 
 
 		 302 aa  163  6e-39  Variovorax paradoxus S110  Bacteria  normal  0.235206  n/a   
 
 
-
 
NC_004578  PSPTO_4080  DNA-binding response regulator, LuxR family  49.34 
 
 		 222 aa  155  7e-37  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.542388  n/a   
 
 
-
 
NC_010814  Glov_1118  response regulator receiver sensor signal transduction histidine kinase  50.74 
 
 		 452 aa  141  1.9999999999999998e-32  Geobacter lovleyi SZ  Bacteria  hitchhiker  0.000972917  n/a   
 
 
-
 
NC_013730  Slin_2507  two component, sigma54 specific, transcriptional regulator, Fis family  51.56 
 
 		 488 aa  140  3e-32  Spirosoma linguale DSM 74  Bacteria  normal  1  normal  0.182398 
 
 
-
 
NC_010571  Oter_0809  response regulator receiver sensor signal transduction histidine kinase  53.91 
 
 		 367 aa  139  8.999999999999999e-32  Opitutus terrae PB90-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010627  Bphy_7700  multi-sensor signal transduction histidine kinase  55.74 
 
 		 541 aa  138  1e-31  Burkholderia phymatum STM815  Bacteria  normal  0.163324  normal  0.507763 
 
 
-
 
NC_013440  Hoch_6548  response regulator receiver sensor signal transduction histidine kinase  53.23 
 
 		 397 aa  138  1e-31  Haliangium ochraceum DSM 14365  Bacteria  normal  1  normal  0.543575 
 
 
-
 
NC_007413  Ava_2149  response regulator receiver Signal transduction histidine kinase  49.22 
 
 		 407 aa  137  2e-31  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  0.142048 
 
 
-
 
NC_010625  Bphy_6559  multi-sensor signal transduction histidine kinase  55.74 
 
 		 541 aa  138  2e-31  Burkholderia phymatum STM815  Bacteria  normal  1  normal  0.59439 
 
 
-
 
NC_007413  Ava_4136  response regulator receiver Signal transduction histidine kinase  54.7 
 
 		 440 aa  137  3.0000000000000003e-31  Anabaena variabilis ATCC 29413  Bacteria  decreased coverage  0.00000660181  hitchhiker  0.00876613 
 
 
-
 
NC_007413  Ava_2562  response regulator receiver Signal transduction histidine kinase  48.89 
 
 		 437 aa  136  6.0000000000000005e-31  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_2347  response regulator receiver protein  50.36 
 
 		 202 aa  135  9.999999999999999e-31  Roseiflexus sp. RS-1  Bacteria  normal  0.56815  normal  1 
 
 
-
 
NC_014248  Aazo_4465  response regulator receiver sensor signal transduction histidine kinase  45.77 
 
 		 437 aa  134  3e-30  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_009767  Rcas_3134  response regulator receiver protein  50 
 
 		 200 aa  134  3e-30  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010676  Bphyt_6236  multi-sensor signal transduction histidine kinase  52.59 
 
 		 553 aa  134  3e-30  Burkholderia phytofirmans PsJN  Bacteria  normal  1  normal  0.914679 
 
 
-
 
NC_012918  GM21_3242  response regulator receiver sensor signal transduction histidine kinase  49.21 
 
 		 441 aa  132  9e-30  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_011884  Cyan7425_3210  response regulator receiver modulated diguanylate cyclase  47.69 
 
 		 337 aa  131  1.0000000000000001e-29  Cyanothece sp. PCC 7425  Bacteria  normal  0.32327  normal  0.712325 
 
 
-
 
NC_011726  PCC8801_1139  response regulator receiver modulated diguanylate cyclase  45.26 
 
 		 308 aa  132  1.0000000000000001e-29  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_1169  response regulator receiver modulated diguanylate cyclase  45.26 
 
 		 308 aa  132  1.0000000000000001e-29  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011884  Cyan7425_0790  multi-sensor signal transduction histidine kinase  45 
 
 		 566 aa  131  2.0000000000000002e-29  Cyanothece sp. PCC 7425  Bacteria  normal  0.391268  normal  1 
 
 
-
 
NC_008312  Tery_4155  response regulator receiver sensor signal transduction histidine kinase  51.24 
 
 		 440 aa  130  4.0000000000000003e-29  Trichodesmium erythraeum IMS101  Bacteria  normal  0.50715  normal  1 
 
 
-
 
NC_011146  Gbem_1018  response regulator receiver sensor signal transduction histidine kinase  48.72 
 
 		 441 aa  130  4.0000000000000003e-29  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.00729938  n/a   
 
 
-
 
NC_013440  Hoch_2175  response regulator receiver sensor signal transduction histidine kinase  52.59 
 
 		 395 aa  129  6e-29  Haliangium ochraceum DSM 14365  Bacteria  normal  0.924768  normal  0.400775 
 
 
-
 
NC_011729  PCC7424_0178  response regulator receiver modulated diguanylate cyclase  50.41 
 
 		 322 aa  129  9.000000000000001e-29  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.895619 
 
 
-
 
NC_010551  BamMC406_1236  response regulator receiver sensor signal transduction histidine kinase  44.09 
 
 		 386 aa  124  4e-27  Burkholderia ambifaria MC40-6  Bacteria  normal  0.493129  normal  1 
 
 
-
 
NC_014248  Aazo_4229  response regulator receiver sensor signal transduction histidine kinase  46.38 
 
 		 383 aa  123  4e-27  'Nostoc azollae' 0708  Bacteria  normal  0.599633  n/a   
 
 
-
 
NC_011726  PCC8801_1350  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  49.17 
 
 		 715 aa  123  5e-27  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_010623  Bphy_4530  response regulator receiver sensor signal transduction histidine kinase  42.66 
 
 		 386 aa  123  6e-27  Burkholderia phymatum STM815  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014248  Aazo_1477  response regulator receiver modulated diguanylate cyclase  43.94 
 
 		 317 aa  123  6e-27  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_1577  response regulator receiver modulated diguanylate cyclase  43.75 
 
 		 314 aa  123  6e-27  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013161  Cyan8802_1380  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  49.17 
 
 		 715 aa  123  6e-27  Cyanothece sp. PCC 8802  Bacteria  normal  0.923401  normal  1 
 
 
-
 
NC_011729  PCC7424_0984  response regulator receiver modulated diguanylate cyclase  45.45 
 
 		 353 aa  122  9.999999999999999e-27  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.194443 
 
 
-
 
NC_010571  Oter_0959  response regulator receiver sensor signal transduction histidine kinase  38.6 
 
 		 372 aa  120  1.9999999999999998e-26  Opitutus terrae PB90-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010002  Daci_1192  response regulator receiver modulated diguanylate cyclase  52.46 
 
 		 316 aa  120  3e-26  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011146  Gbem_1228  response regulator receiver modulated diguanylate cyclase  47.54 
 
 		 349 aa  119  9.999999999999999e-26  Geobacter bemidjiensis Bem  Bacteria  normal  1  n/a   
 
 
-
 
NC_008554  Sfum_2303  response regulator receiver protein  45.04 
 
 		 227 aa  117  1.9999999999999998e-25  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011726  PCC8801_2041  response regulator receiver modulated diguanylate cyclase  46.61 
 
 		 317 aa  117  3e-25  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_008609  Ppro_2062  response regulator receiver protein  43.8 
 
 		 217 aa  117  3e-25  Pelobacter propionicus DSM 2379  Bacteria  normal  1  n/a   
 
 
-
 
NC_013161  Cyan8802_2067  response regulator receiver modulated diguanylate cyclase  46.61 
 
 		 317 aa  117  3e-25  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012880  Dd703_3123  response regulator receiver modulated diguanylate cyclase  31.86 
 
 		 312 aa  117  3.9999999999999997e-25  Dickeya dadantii Ech703  Bacteria  normal  1  n/a   
 
 
-
 
NC_009654  Mmwyl1_2382  response regulator receiver modulated metal dependent phosphohydrolase  44.36 
 
 		 359 aa  117  3.9999999999999997e-25  Marinomonas sp. MWYL1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008321  Shewmr4_0481  response regulator receiver modulated metal dependent phosphohydrolase  47.2 
 
 		 348 aa  117  3.9999999999999997e-25  Shewanella sp. MR-4  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008322  Shewmr7_3549  response regulator receiver modulated metal dependent phosphohydrolase  47.2 
 
 		 348 aa  117  3.9999999999999997e-25  Shewanella sp. MR-7  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011992  Dtpsy_0962  response regulator receiver modulated metal dependent phosphohydrolase  52.14 
 
 		 377 aa  116  5e-25  Acidovorax ebreus TPSY  Bacteria  normal  0.115091  n/a   
 
 
-
 
NC_013161  Cyan8802_3359  response regulator receiver sensor signal transduction histidine kinase  44.35 
 
 		 395 aa  116  5e-25  Cyanothece sp. PCC 8802  Bacteria  normal  0.361398  normal  1 
 
 
-
 
NC_011726  PCC8801_2743  response regulator receiver sensor signal transduction histidine kinase  44.35 
 
 		 395 aa  116  5e-25  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_007298  Daro_3005  response regulator receiver  40.76 
 
 		 361 aa  116  7.999999999999999e-25  Dechloromonas aromatica RCB  Bacteria  normal  0.931132  normal  1 
 
 
-
 
NC_007413  Ava_2150  response regulator receiver Signal transduction histidine kinase  45 
 
 		 443 aa  116  7.999999999999999e-25  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  0.394463 
 
 
-
 
NC_008709  Ping_0978  response regulator receiver modulated diguanylate cyclase  47.01 
 
 		 322 aa  115  1.0000000000000001e-24  Psychromonas ingrahamii 37  Bacteria  normal  0.97362  decreased coverage  0.00116316 
 
 
-
 
NC_011769  DvMF_1097  response regulator receiver modulated metal dependent phosphohydrolase  50.85 
 
 		 391 aa  115  1.0000000000000001e-24  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.151318 
 
 
-
 
NC_008782  Ajs_1044  response regulator receiver modulated metal dependent phosphohydrolase  52.14 
 
 		 377 aa  115  1.0000000000000001e-24  Acidovorax sp. JS42  Bacteria  normal  1  normal  0.0516082 
 
 
-
 
NC_013522  Taci_1373  response regulator receiver modulated metal dependent phosphohydrolase  47.62 
 
 		 365 aa  115  1.0000000000000001e-24  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  1  n/a   
 
 
-
 
NC_008577  Shewana3_0479  response regulator receiver modulated metal dependent phosphohydrolase  45.24 
 
 		 350 aa  115  1.0000000000000001e-24  Shewanella sp. ANA-3  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010524  Lcho_2452  response regulator receiver modulated metal dependent phosphohydrolase  43.02 
 
 		 377 aa  115  2.0000000000000002e-24  Leptothrix cholodnii SP-6  Bacteria  n/a    hitchhiker  0.00101758 
 
 
-
 
NC_010681  Bphyt_2397  two component transcriptional regulator, AraC family  46.09 
 
 		 269 aa  114  2.0000000000000002e-24  Burkholderia phytofirmans PsJN  Bacteria  normal  0.92999  normal  0.351016 
 
 
-
 
NC_008062  Bcen_6528  two component AraC family transcriptional regulator  45.19 
 
 		 271 aa  114  2.0000000000000002e-24  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.485144  n/a   
 
 
-
 
NC_008544  Bcen2424_6762  two component AraC family transcriptional regulator  45.19 
 
 		 271 aa  114  2.0000000000000002e-24  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  0.295507 
 
 
-
 
NC_010524  Lcho_3544  response regulator receiver modulated diguanylate cyclase  44.03 
 
 		 322 aa  114  3e-24  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0106122 
 
 
-
 
NC_008576  Mmc1_3408  response regulator receiver modulated metal dependent phosphohydrolase  51.28 
 
 		 346 aa  114  3e-24  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010557  BamMC406_6071  two component AraC family transcriptional regulator  46.4 
 
 		 271 aa  113  4.0000000000000004e-24  Burkholderia ambifaria MC40-6  Bacteria  normal  1  normal  1 
 
 
-
 
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