More than 300 homologs were found in PanDaTox collection
for query gene Mext_3383 on replicon NC_010172
Organism: Methylobacterium extorquens PA1



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010172  Mext_3383  response regulator receiver  100 
 
 
300 aa  587  1e-167  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_3692  two component transcriptional regulator, LuxR family  99.67 
 
 
300 aa  586  1e-166  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.170876  normal 
 
 
-
 
NC_010725  Mpop_3574  two component transcriptional regulator, LuxR family  92.03 
 
 
301 aa  527  1e-149  Methylobacterium populi BJ001  Bacteria  normal  0.0249095  normal 
 
 
-
 
NC_010505  Mrad2831_5514  two component LuxR family transcriptional regulator  82.03 
 
 
305 aa  434  1e-121  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.211273 
 
 
-
 
NC_010511  M446_0591  two component LuxR family transcriptional regulator  68.21 
 
 
301 aa  369  1e-101  Methylobacterium sp. 4-46  Bacteria  normal  0.477799  hitchhiker  0.00469436 
 
 
-
 
NC_010581  Bind_0974  two component LuxR family transcriptional regulator  59.47 
 
 
309 aa  333  3e-90  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.883175  normal  0.426964 
 
 
-
 
NC_011004  Rpal_1441  two component transcriptional regulator, LuxR family  59.86 
 
 
308 aa  320  1.9999999999999998e-86  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007778  RPB_1250  two component LuxR family transcriptional regulator  58.68 
 
 
309 aa  318  5e-86  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.886948  normal 
 
 
-
 
NC_009485  BBta_0652  two component LuxR family transcriptional regulator  56.85 
 
 
305 aa  317  1e-85  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.0800453  normal  0.813173 
 
 
-
 
NC_007958  RPD_3866  response regulator receiver  58.33 
 
 
309 aa  312  3.9999999999999997e-84  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.370865  normal 
 
 
-
 
NC_009620  Smed_4179  response regulator receiver protein  55.22 
 
 
309 aa  311  9e-84  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.15819 
 
 
-
 
NC_011369  Rleg2_3066  two component transcriptional regulator, LuxR family  55.85 
 
 
305 aa  309  4e-83  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_012850  Rleg_3321  two component transcriptional regulator, LuxR family  54.18 
 
 
305 aa  301  1e-80  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.536368 
 
 
-
 
NC_011666  Msil_2002  two component transcriptional regulator, LuxR family  53.04 
 
 
306 aa  299  4e-80  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_011989  Avi_3499  transcriptional regulator LuxR family  54.4 
 
 
312 aa  293  3e-78  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_008740  Maqu_3869  response regulator receiver protein  51.33 
 
 
301 aa  290  2e-77  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_2977  response regulator receiver domain-containing protein  48.83 
 
 
303 aa  283  3.0000000000000004e-75  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.13601 
 
 
-
 
NC_009654  Mmwyl1_0962  response regulator receiver protein  49.19 
 
 
304 aa  272  4.0000000000000004e-72  Marinomonas sp. MWYL1  Bacteria  normal  0.512477  normal 
 
 
-
 
NC_011138  MADE_00878  two-component response regulator  45.92 
 
 
298 aa  264  2e-69  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_007794  Saro_1665  two component LuxR family transcriptional regulator  45.99 
 
 
307 aa  252  4.0000000000000004e-66  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  n/a   
 
 
-
 
NC_008709  Ping_2984  two component transcriptional regulator, LuxR family protein  45.18 
 
 
295 aa  251  7e-66  Psychromonas ingrahamii 37  Bacteria  normal  0.43543  normal  0.546259 
 
 
-
 
NC_007947  Mfla_1761  two component LuxR family transcriptional regulator  47.91 
 
 
311 aa  251  1e-65  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_008825  Mpe_A0671  two component LuxR family transcriptional regulator  48.66 
 
 
333 aa  249  3e-65  Methylibium petroleiphilum PM1  Bacteria  normal  0.0205263  normal 
 
 
-
 
NC_007298  Daro_1445  two component LuxR family transcriptional regulator  47.57 
 
 
308 aa  244  1.9999999999999999e-63  Dechloromonas aromatica RCB  Bacteria  normal  0.446624  normal 
 
 
-
 
NC_008781  Pnap_0979  response regulator receiver protein  44.55 
 
 
336 aa  243  3e-63  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_007908  Rfer_3397  two component LuxR family transcriptional regulator  46.2 
 
 
328 aa  238  8e-62  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_008786  Veis_1731  response regulator receiver protein  45.83 
 
 
361 aa  237  2e-61  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal  0.319975 
 
 
-
 
NC_013422  Hneap_1587  two component transcriptional regulator, LuxR family  46.15 
 
 
292 aa  237  2e-61  Halothiobacillus neapolitanus c2  Bacteria  normal  0.522901  n/a   
 
 
-
 
NC_007948  Bpro_0562  two component LuxR family transcriptional regulator  47.39 
 
 
297 aa  235  6e-61  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_008825  Mpe_A3585  two component LuxR family transcriptional regulator  48.1 
 
 
306 aa  234  1.0000000000000001e-60  Methylibium petroleiphilum PM1  Bacteria  normal  0.295986  normal 
 
 
-
 
NC_008752  Aave_3524  two component LuxR family transcriptional regulator  45.28 
 
 
353 aa  233  4.0000000000000004e-60  Acidovorax citrulli AAC00-1  Bacteria  normal  0.406085  normal  0.428998 
 
 
-
 
NC_010524  Lcho_1083  two component LuxR family transcriptional regulator  48.51 
 
 
316 aa  233  4.0000000000000004e-60  Leptothrix cholodnii SP-6  Bacteria  n/a    normal 
 
 
-
 
NC_012791  Vapar_4238  two component transcriptional regulator, LuxR family  41.32 
 
 
356 aa  232  5e-60  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_007948  Bpro_1354  two component LuxR family transcriptional regulator  45.03 
 
 
349 aa  231  1e-59  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_0218  two component LuxR family transcriptional regulator  43.81 
 
 
339 aa  230  2e-59  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_012791  Vapar_3147  two component transcriptional regulator, LuxR family  48.77 
 
 
302 aa  226  4e-58  Variovorax paradoxus S110  Bacteria  normal  0.235206  n/a   
 
 
-
 
NC_010515  Bcenmc03_5666  two component LuxR family transcriptional regulator  42.52 
 
 
312 aa  226  5.0000000000000005e-58  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.917296 
 
 
-
 
NC_008061  Bcen_3730  two component LuxR family transcriptional regulator  42.19 
 
 
312 aa  224  2e-57  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_008543  Bcen2424_4638  two component LuxR family transcriptional regulator  42.19 
 
 
312 aa  224  2e-57  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B1713  two component LuxR family transcriptional regulator  39.05 
 
 
361 aa  210  2e-53  Burkholderia xenovorans LB400  Bacteria  normal  0.310925  normal 
 
 
-
 
NC_010571  Oter_1720  two component LuxR family transcriptional regulator  37.98 
 
 
301 aa  158  8e-38  Opitutus terrae PB90-1  Bacteria  normal  0.162572  normal  0.616267 
 
 
-
 
NC_004578  PSPTO_4080  DNA-binding response regulator, LuxR family  49.22 
 
 
222 aa  145  1e-33  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.542388  n/a   
 
 
-
 
NC_011884  Cyan7425_3210  response regulator receiver modulated diguanylate cyclase  55.17 
 
 
337 aa  133  5e-30  Cyanothece sp. PCC 7425  Bacteria  normal  0.32327  normal  0.712325 
 
 
-
 
NC_013440  Hoch_6548  response regulator receiver sensor signal transduction histidine kinase  52.07 
 
 
397 aa  130  2.0000000000000002e-29  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.543575 
 
 
-
 
NC_013730  Slin_2507  two component, sigma54 specific, transcriptional regulator, Fis family  50 
 
 
488 aa  128  1.0000000000000001e-28  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.182398 
 
 
-
 
NC_009767  Rcas_3134  response regulator receiver protein  43.95 
 
 
200 aa  126  4.0000000000000003e-28  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_007413  Ava_2149  response regulator receiver Signal transduction histidine kinase  52.07 
 
 
407 aa  126  5e-28  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.142048 
 
 
-
 
NC_007413  Ava_2562  response regulator receiver Signal transduction histidine kinase  50.86 
 
 
437 aa  126  5e-28  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_011884  Cyan7425_0790  multi-sensor signal transduction histidine kinase  47.93 
 
 
566 aa  125  6e-28  Cyanothece sp. PCC 7425  Bacteria  normal  0.391268  normal 
 
 
-
 
NC_014248  Aazo_4465  response regulator receiver sensor signal transduction histidine kinase  48.78 
 
 
437 aa  125  7e-28  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_0809  response regulator receiver sensor signal transduction histidine kinase  49.18 
 
 
367 aa  124  1e-27  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_007413  Ava_4136  response regulator receiver Signal transduction histidine kinase  50 
 
 
440 aa  124  3e-27  Anabaena variabilis ATCC 29413  Bacteria  decreased coverage  0.00000660181  hitchhiker  0.00876613 
 
 
-
 
NC_010814  Glov_1118  response regulator receiver sensor signal transduction histidine kinase  44.93 
 
 
452 aa  122  8e-27  Geobacter lovleyi SZ  Bacteria  hitchhiker  0.000972917  n/a   
 
 
-
 
NC_010627  Bphy_7700  multi-sensor signal transduction histidine kinase  51.69 
 
 
541 aa  120  3.9999999999999996e-26  Burkholderia phymatum STM815  Bacteria  normal  0.163324  normal  0.507763 
 
 
-
 
NC_013440  Hoch_2175  response regulator receiver sensor signal transduction histidine kinase  48.33 
 
 
395 aa  120  3.9999999999999996e-26  Haliangium ochraceum DSM 14365  Bacteria  normal  0.924768  normal  0.400775 
 
 
-
 
NC_010625  Bphy_6559  multi-sensor signal transduction histidine kinase  50.86 
 
 
541 aa  119  3.9999999999999996e-26  Burkholderia phymatum STM815  Bacteria  normal  normal  0.59439 
 
 
-
 
NC_007796  Mhun_1941  response regulator receiver domain-containing protein  48.72 
 
 
156 aa  119  4.9999999999999996e-26  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_013161  Cyan8802_1380  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  36.69 
 
 
715 aa  119  9e-26  Cyanothece sp. PCC 8802  Bacteria  normal  0.923401  normal 
 
 
-
 
NC_008312  Tery_4155  response regulator receiver sensor signal transduction histidine kinase  41.46 
 
 
440 aa  118  9.999999999999999e-26  Trichodesmium erythraeum IMS101  Bacteria  normal  0.50715  normal 
 
 
-
 
NC_011726  PCC8801_1350  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  36.69 
 
 
715 aa  118  9.999999999999999e-26  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_010676  Bphyt_6236  multi-sensor signal transduction histidine kinase  47.5 
 
 
553 aa  117  1.9999999999999998e-25  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.914679 
 
 
-
 
NC_009012  Cthe_1826  response regulator receiver sensor signal transduction histidine kinase  39.57 
 
 
363 aa  116  5e-25  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_010681  Bphyt_2397  two component transcriptional regulator, AraC family  34.63 
 
 
269 aa  115  6e-25  Burkholderia phytofirmans PsJN  Bacteria  normal  0.92999  normal  0.351016 
 
 
-
 
NC_013216  Dtox_1577  response regulator receiver modulated diguanylate cyclase  41.27 
 
 
314 aa  114  1.0000000000000001e-24  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_1006  response regulator receiver modulated diguanylate cyclase  35.66 
 
 
312 aa  115  1.0000000000000001e-24  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_011138  MADE_03429  two-component system response regulator (hybrid family) protein  36.06 
 
 
358 aa  115  1.0000000000000001e-24  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_3794  response regulator receiver sensor signal transduction histidine kinase  44.9 
 
 
376 aa  114  2.0000000000000002e-24  Opitutus terrae PB90-1  Bacteria  normal  0.0277983  normal  0.543799 
 
 
-
 
NC_008709  Ping_0978  response regulator receiver modulated diguanylate cyclase  40 
 
 
322 aa  114  2.0000000000000002e-24  Psychromonas ingrahamii 37  Bacteria  normal  0.97362  decreased coverage  0.00116316 
 
 
-
 
NC_009654  Mmwyl1_2382  response regulator receiver modulated metal dependent phosphohydrolase  44.12 
 
 
359 aa  113  4.0000000000000004e-24  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_2347  response regulator receiver protein  41.14 
 
 
202 aa  113  4.0000000000000004e-24  Roseiflexus sp. RS-1  Bacteria  normal  0.56815  normal 
 
 
-
 
NC_013522  Taci_0090  two component transcriptional regulator, winged helix family  33.85 
 
 
228 aa  112  5e-24  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_1192  response regulator receiver modulated diguanylate cyclase  49.59 
 
 
316 aa  112  6e-24  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_014248  Aazo_4229  response regulator receiver sensor signal transduction histidine kinase  41.91 
 
 
383 aa  111  1.0000000000000001e-23  'Nostoc azollae' 0708  Bacteria  normal  0.599633  n/a   
 
 
-
 
NC_008554  Sfum_2303  response regulator receiver protein  43.38 
 
 
227 aa  111  1.0000000000000001e-23  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_1228  response regulator receiver modulated diguanylate cyclase  41.38 
 
 
349 aa  110  2.0000000000000002e-23  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_2150  response regulator receiver Signal transduction histidine kinase  44.63 
 
 
443 aa  111  2.0000000000000002e-23  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.394463 
 
 
-
 
NC_010551  BamMC406_1236  response regulator receiver sensor signal transduction histidine kinase  41.73 
 
 
386 aa  110  2.0000000000000002e-23  Burkholderia ambifaria MC40-6  Bacteria  normal  0.493129  normal 
 
 
-
 
NC_012918  GM21_3242  response regulator receiver sensor signal transduction histidine kinase  43.97 
 
 
441 aa  110  2.0000000000000002e-23  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011729  PCC7424_2188  response regulator receiver sensor signal transduction histidine kinase  39.53 
 
 
384 aa  111  2.0000000000000002e-23  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.00677544 
 
 
-
 
NC_011726  PCC8801_2743  response regulator receiver sensor signal transduction histidine kinase  37.04 
 
 
395 aa  110  3e-23  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_3359  response regulator receiver sensor signal transduction histidine kinase  37.04 
 
 
395 aa  110  3e-23  Cyanothece sp. PCC 8802  Bacteria  normal  0.361398  normal 
 
 
-
 
NC_011146  Gbem_1018  response regulator receiver sensor signal transduction histidine kinase  39.85 
 
 
441 aa  109  5e-23  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.00729938  n/a   
 
 
-
 
NC_010623  Bphy_4530  response regulator receiver sensor signal transduction histidine kinase  39.51 
 
 
386 aa  109  5e-23  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_2725  two component transcriptional regulator  37.06 
 
 
226 aa  109  5e-23  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0716975  n/a   
 
 
-
 
NC_010571  Oter_3856  response regulator receiver sensor signal transduction histidine kinase  37.59 
 
 
378 aa  109  6e-23  Opitutus terrae PB90-1  Bacteria  normal  normal  0.215089 
 
 
-
 
NC_008340  Mlg_2429  response regulator receiver modulated metal dependent phosphohydrolase  40.41 
 
 
480 aa  109  6e-23  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal  0.129673 
 
 
-
 
NC_010524  Lcho_3702  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  46.03 
 
 
863 aa  109  6e-23  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.170309 
 
 
-
 
NC_011729  PCC7424_0984  response regulator receiver modulated diguanylate cyclase  36.42 
 
 
353 aa  108  7.000000000000001e-23  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.194443 
 
 
-
 
NC_013161  Cyan8802_1169  response regulator receiver modulated diguanylate cyclase  36.3 
 
 
308 aa  108  7.000000000000001e-23  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_1139  response regulator receiver modulated diguanylate cyclase  36.3 
 
 
308 aa  108  7.000000000000001e-23  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_011729  PCC7424_0178  response regulator receiver modulated diguanylate cyclase  33.18 
 
 
322 aa  107  2e-22  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.895619 
 
 
-
 
NC_014248  Aazo_5066  response regulator receiver modulated diguanylate cyclase  42.48 
 
 
338 aa  107  3e-22  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_008576  Mmc1_3071  response regulator receiver protein  40.88 
 
 
390 aa  107  3e-22  Magnetococcus sp. MC-1  Bacteria  normal  hitchhiker  0.000442652 
 
 
-
 
NC_010557  BamMC406_6071  two component AraC family transcriptional regulator  42.5 
 
 
271 aa  106  4e-22  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_010506  Swoo_2978  response regulator receiver modulated metal dependent phosphohydrolase  43.7 
 
 
369 aa  106  4e-22  Shewanella woodyi ATCC 51908  Bacteria  normal  normal  0.806511 
 
 
-
 
NC_008576  Mmc1_2393  response regulator receiver sensor hybrid histidine kinase  42.86 
 
 
518 aa  106  5e-22  Magnetococcus sp. MC-1  Bacteria  normal  0.991201  normal  0.0787545 
 
 
-
 
NC_007298  Daro_0007  response regulator receiver modulated metal dependent phosphohydrolase  45.76 
 
 
379 aa  105  6e-22  Dechloromonas aromatica RCB  Bacteria  normal  0.829613  normal  0.0284762 
 
 
-
 
NC_010814  Glov_3523  response regulator receiver modulated metal dependent phosphohydrolase  46.15 
 
 
363 aa  105  6e-22  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011992  Dtpsy_0962  response regulator receiver modulated metal dependent phosphohydrolase  42.96 
 
 
377 aa  105  6e-22  Acidovorax ebreus TPSY  Bacteria  normal  0.115091  n/a   
 
 
-
 
NC_008345  Sfri_2505  response regulator receiver modulated metal dependent phosphohydrolase  40.58 
 
 
331 aa  105  6e-22  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
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