More than 300 homologs were found in PanDaTox collection
for query gene Maqu_3869 on replicon NC_008740
Organism: Marinobacter aquaeolei VT8



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_008740  Maqu_3869  response regulator receiver protein  100 
 
 		 301 aa  619  1e-176  Marinobacter aquaeolei VT8  Bacteria  normal  1  n/a   
 
 
-
 
NC_009654  Mmwyl1_0962  response regulator receiver protein  52.65 
 
 		 304 aa  312  3.9999999999999997e-84  Marinomonas sp. MWYL1  Bacteria  normal  0.512477  normal  1 
 
 
-
 
NC_007912  Sde_2977  response regulator receiver domain-containing protein  52.03 
 
 		 303 aa  307  1.0000000000000001e-82  Saccharophagus degradans 2-40  Bacteria  normal  1  normal  0.13601 
 
 
-
 
NC_009485  BBta_0652  two component LuxR family transcriptional regulator  50.5 
 
 		 305 aa  292  4e-78  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.0800453  normal  0.813173 
 
 
-
 
NC_010581  Bind_0974  two component LuxR family transcriptional regulator  50.81 
 
 		 309 aa  288  6e-77  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.883175  normal  0.426964 
 
 
-
 
NC_011369  Rleg2_3066  two component transcriptional regulator, LuxR family  49.17 
 
 		 305 aa  288  1e-76  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007778  RPB_1250  two component LuxR family transcriptional regulator  51.38 
 
 		 309 aa  286  2e-76  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.886948  normal  1 
 
 
-
 
NC_007958  RPD_3866  response regulator receiver  50 
 
 		 309 aa  285  5e-76  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.370865  normal  1 
 
 
-
 
NC_012850  Rleg_3321  two component transcriptional regulator, LuxR family  47.85 
 
 		 305 aa  281  1e-74  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  1  normal  0.536368 
 
 
-
 
NC_011004  Rpal_1441  two component transcriptional regulator, LuxR family  50 
 
 		 308 aa  280  2e-74  Rhodopseudomonas palustris TIE-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009620  Smed_4179  response regulator receiver protein  47.99 
 
 		 309 aa  280  2e-74  Sinorhizobium medicae WSM419  Bacteria  normal  1  normal  0.15819 
 
 
-
 
NC_010511  M446_0591  two component LuxR family transcriptional regulator  49.83 
 
 		 301 aa  278  1e-73  Methylobacterium sp. 4-46  Bacteria  normal  0.477799  hitchhiker  0.00469436 
 
 
-
 
NC_011989  Avi_3499  transcriptional regulator LuxR family  48.49 
 
 		 312 aa  275  8e-73  Agrobacterium vitis S4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011757  Mchl_3692  two component transcriptional regulator, LuxR family  51.67 
 
 		 300 aa  274  1.0000000000000001e-72  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.170876  normal  1 
 
 
-
 
NC_010172  Mext_3383  response regulator receiver  51.33 
 
 		 300 aa  273  2.0000000000000002e-72  Methylobacterium extorquens PA1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010725  Mpop_3574  two component transcriptional regulator, LuxR family  50.34 
 
 		 301 aa  271  1e-71  Methylobacterium populi BJ001  Bacteria  normal  0.0249095  normal  1 
 
 
-
 
NC_011138  MADE_00878  two-component response regulator  46.76 
 
 		 298 aa  262  4e-69  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_011666  Msil_2002  two component transcriptional regulator, LuxR family  47.81 
 
 		 306 aa  262  6e-69  Methylocella silvestris BL2  Bacteria  n/a    normal  1 
 
 
-
 
NC_010505  Mrad2831_5514  two component LuxR family transcriptional regulator  49.66 
 
 		 305 aa  255  6e-67  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  1  normal  0.211273 
 
 
-
 
NC_008709  Ping_2984  two component transcriptional regulator, LuxR family protein  47.19 
 
 		 295 aa  251  8.000000000000001e-66  Psychromonas ingrahamii 37  Bacteria  normal  0.43543  normal  0.546259 
 
 
-
 
NC_008825  Mpe_A0671  two component LuxR family transcriptional regulator  47.49 
 
 		 333 aa  241  1e-62  Methylibium petroleiphilum PM1  Bacteria  normal  0.0205263  normal  1 
 
 
-
 
NC_013422  Hneap_1587  two component transcriptional regulator, LuxR family  45.33 
 
 		 292 aa  239  4e-62  Halothiobacillus neapolitanus c2  Bacteria  normal  0.522901  n/a   
 
 
-
 
NC_010002  Daci_0218  two component LuxR family transcriptional regulator  43.61 
 
 		 339 aa  237  2e-61  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008825  Mpe_A3585  two component LuxR family transcriptional regulator  46.39 
 
 		 306 aa  233  4.0000000000000004e-60  Methylibium petroleiphilum PM1  Bacteria  normal  0.295986  normal  1 
 
 
-
 
NC_007948  Bpro_0562  two component LuxR family transcriptional regulator  44.71 
 
 		 297 aa  231  1e-59  Polaromonas sp. JS666  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007794  Saro_1665  two component LuxR family transcriptional regulator  41.18 
 
 		 307 aa  227  1e-58  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  1  n/a   
 
 
-
 
NC_007947  Mfla_1761  two component LuxR family transcriptional regulator  44.17 
 
 		 311 aa  224  2e-57  Methylobacillus flagellatus KT  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007908  Rfer_3397  two component LuxR family transcriptional regulator  45.97 
 
 		 328 aa  221  9.999999999999999e-57  Rhodoferax ferrireducens T118  Bacteria  normal  1  n/a   
 
 
-
 
NC_008781  Pnap_0979  response regulator receiver protein  43.37 
 
 		 336 aa  220  1.9999999999999999e-56  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012791  Vapar_3147  two component transcriptional regulator, LuxR family  44.76 
 
 		 302 aa  220  1.9999999999999999e-56  Variovorax paradoxus S110  Bacteria  normal  0.235206  n/a   
 
 
-
 
NC_008786  Veis_1731  response regulator receiver protein  42.73 
 
 		 361 aa  214  9.999999999999999e-55  Verminephrobacter eiseniae EF01-2  Bacteria  normal  1  normal  0.319975 
 
 
-
 
NC_010515  Bcenmc03_5666  two component LuxR family transcriptional regulator  39.87 
 
 		 312 aa  213  2.9999999999999995e-54  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.917296 
 
 
-
 
NC_007298  Daro_1445  two component LuxR family transcriptional regulator  46 
 
 		 308 aa  212  5.999999999999999e-54  Dechloromonas aromatica RCB  Bacteria  normal  0.446624  normal  1 
 
 
-
 
NC_008061  Bcen_3730  two component LuxR family transcriptional regulator  39.87 
 
 		 312 aa  212  5.999999999999999e-54  Burkholderia cenocepacia AU 1054  Bacteria  normal  1  n/a   
 
 
-
 
NC_010524  Lcho_1083  two component LuxR family transcriptional regulator  44.34 
 
 		 316 aa  212  5.999999999999999e-54  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  1 
 
 
-
 
NC_008543  Bcen2424_4638  two component LuxR family transcriptional regulator  39.87 
 
 		 312 aa  212  5.999999999999999e-54  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008752  Aave_3524  two component LuxR family transcriptional regulator  41.67 
 
 		 353 aa  209  4e-53  Acidovorax citrulli AAC00-1  Bacteria  normal  0.406085  normal  0.428998 
 
 
-
 
NC_007948  Bpro_1354  two component LuxR family transcriptional regulator  41.67 
 
 		 349 aa  207  2e-52  Polaromonas sp. JS666  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012791  Vapar_4238  two component transcriptional regulator, LuxR family  39.82 
 
 		 356 aa  206  4e-52  Variovorax paradoxus S110  Bacteria  normal  1  n/a   
 
 
-
 
NC_007952  Bxe_B1713  two component LuxR family transcriptional regulator  37.91 
 
 		 361 aa  205  9e-52  Burkholderia xenovorans LB400  Bacteria  normal  0.310925  normal  1 
 
 
-
 
NC_004578  PSPTO_4080  DNA-binding response regulator, LuxR family  50.34 
 
 		 222 aa  153  4e-36  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.542388  n/a   
 
 
-
 
NC_010571  Oter_1720  two component LuxR family transcriptional regulator  34.17 
 
 		 301 aa  152  8.999999999999999e-36  Opitutus terrae PB90-1  Bacteria  normal  0.162572  normal  0.616267 
 
 
-
 
NC_011884  Cyan7425_3210  response regulator receiver modulated diguanylate cyclase  50 
 
 		 337 aa  129  7.000000000000001e-29  Cyanothece sp. PCC 7425  Bacteria  normal  0.32327  normal  0.712325 
 
 
-
 
NC_007413  Ava_2149  response regulator receiver Signal transduction histidine kinase  45.89 
 
 		 407 aa  128  1.0000000000000001e-28  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  0.142048 
 
 
-
 
NC_013730  Slin_2507  two component, sigma54 specific, transcriptional regulator, Fis family  46.03 
 
 		 488 aa  125  1e-27  Spirosoma linguale DSM 74  Bacteria  normal  1  normal  0.182398 
 
 
-
 
NC_013440  Hoch_6548  response regulator receiver sensor signal transduction histidine kinase  47.58 
 
 		 397 aa  124  2e-27  Haliangium ochraceum DSM 14365  Bacteria  normal  1  normal  0.543575 
 
 
-
 
NC_011884  Cyan7425_0790  multi-sensor signal transduction histidine kinase  45.52 
 
 		 566 aa  124  2e-27  Cyanothece sp. PCC 7425  Bacteria  normal  0.391268  normal  1 
 
 
-
 
NC_007413  Ava_2562  response regulator receiver Signal transduction histidine kinase  44.44 
 
 		 437 aa  123  3e-27  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010814  Glov_1118  response regulator receiver sensor signal transduction histidine kinase  46.09 
 
 		 452 aa  123  4e-27  Geobacter lovleyi SZ  Bacteria  hitchhiker  0.000972917  n/a   
 
 
-
 
NC_010623  Bphy_4530  response regulator receiver sensor signal transduction histidine kinase  44.44 
 
 		 386 aa  121  1.9999999999999998e-26  Burkholderia phymatum STM815  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014248  Aazo_4465  response regulator receiver sensor signal transduction histidine kinase  42.19 
 
 		 437 aa  120  1.9999999999999998e-26  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_007413  Ava_2150  response regulator receiver Signal transduction histidine kinase  47.46 
 
 		 443 aa  120  3e-26  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  0.394463 
 
 
-
 
NC_010625  Bphy_6559  multi-sensor signal transduction histidine kinase  50.86 
 
 		 541 aa  120  3e-26  Burkholderia phymatum STM815  Bacteria  normal  1  normal  0.59439 
 
 
-
 
NC_010551  BamMC406_1236  response regulator receiver sensor signal transduction histidine kinase  43.65 
 
 		 386 aa  120  3.9999999999999996e-26  Burkholderia ambifaria MC40-6  Bacteria  normal  0.493129  normal  1 
 
 
-
 
NC_010627  Bphy_7700  multi-sensor signal transduction histidine kinase  51.72 
 
 		 541 aa  119  6e-26  Burkholderia phymatum STM815  Bacteria  normal  0.163324  normal  0.507763 
 
 
-
 
NC_013440  Hoch_2175  response regulator receiver sensor signal transduction histidine kinase  46.28 
 
 		 395 aa  119  6e-26  Haliangium ochraceum DSM 14365  Bacteria  normal  0.924768  normal  0.400775 
 
 
-
 
NC_009767  Rcas_3134  response regulator receiver protein  45.97 
 
 		 200 aa  117  1.9999999999999998e-25  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010681  Bphyt_2397  two component transcriptional regulator, AraC family  46.4 
 
 		 269 aa  117  3e-25  Burkholderia phytofirmans PsJN  Bacteria  normal  0.92999  normal  0.351016 
 
 
-
 
NC_011146  Gbem_1018  response regulator receiver sensor signal transduction histidine kinase  41.27 
 
 		 441 aa  116  5e-25  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.00729938  n/a   
 
 
-
 
NC_010571  Oter_0809  response regulator receiver sensor signal transduction histidine kinase  44.63 
 
 		 367 aa  115  6.9999999999999995e-25  Opitutus terrae PB90-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008709  Ping_0978  response regulator receiver modulated diguanylate cyclase  35.68 
 
 		 322 aa  115  6.9999999999999995e-25  Psychromonas ingrahamii 37  Bacteria  normal  0.97362  decreased coverage  0.00116316 
 
 
-
 
NC_007413  Ava_4136  response regulator receiver Signal transduction histidine kinase  40.16 
 
 		 440 aa  115  7.999999999999999e-25  Anabaena variabilis ATCC 29413  Bacteria  decreased coverage  0.00000660181  hitchhiker  0.00876613 
 
 
-
 
NC_010571  Oter_0959  response regulator receiver sensor signal transduction histidine kinase  46.15 
 
 		 372 aa  115  1.0000000000000001e-24  Opitutus terrae PB90-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012918  GM21_3242  response regulator receiver sensor signal transduction histidine kinase  42.28 
 
 		 441 aa  115  1.0000000000000001e-24  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_013216  Dtox_1577  response regulator receiver modulated diguanylate cyclase  45.69 
 
 		 314 aa  114  2.0000000000000002e-24  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009523  RoseRS_2347  response regulator receiver protein  44.36 
 
 		 202 aa  114  2.0000000000000002e-24  Roseiflexus sp. RS-1  Bacteria  normal  0.56815  normal  1 
 
 
-
 
NC_011769  DvMF_1097  response regulator receiver modulated metal dependent phosphohydrolase  47.2 
 
 		 391 aa  113  4.0000000000000004e-24  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.151318 
 
 
-
 
NC_010676  Bphyt_6236  multi-sensor signal transduction histidine kinase  44.44 
 
 		 553 aa  113  4.0000000000000004e-24  Burkholderia phytofirmans PsJN  Bacteria  normal  1  normal  0.914679 
 
 
-
 
NC_013161  Cyan8802_1169  response regulator receiver modulated diguanylate cyclase  29.12 
 
 		 308 aa  112  8.000000000000001e-24  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011726  PCC8801_1139  response regulator receiver modulated diguanylate cyclase  29.12 
 
 		 308 aa  112  8.000000000000001e-24  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_010557  BamMC406_6071  two component AraC family transcriptional regulator  44.17 
 
 		 271 aa  112  9e-24  Burkholderia ambifaria MC40-6  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008392  Bamb_6368  two component AraC family transcriptional regulator  44.17 
 
 		 271 aa  111  1.0000000000000001e-23  Burkholderia ambifaria AMMD  Bacteria  normal  0.434467  normal  1 
 
 
-
 
NC_008554  Sfum_2303  response regulator receiver protein  42.65 
 
 		 227 aa  110  2.0000000000000002e-23  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011726  PCC8801_1350  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  40 
 
 		 715 aa  110  3e-23  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_007509  Bcep18194_C7377  two component AraC family transcriptional regulator  41.54 
 
 		 278 aa  110  4.0000000000000004e-23  Burkholderia sp. 383  Bacteria  normal  0.0377301  normal  0.284562 
 
 
-
 
NC_009012  Cthe_1826  response regulator receiver sensor signal transduction histidine kinase  39.55 
 
 		 363 aa  109  4.0000000000000004e-23  Clostridium thermocellum ATCC 27405  Bacteria  normal  1  n/a   
 
 
-
 
NC_013161  Cyan8802_1380  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  40 
 
 		 715 aa  109  5e-23  Cyanothece sp. PCC 8802  Bacteria  normal  0.923401  normal  1 
 
 
-
 
NC_008312  Tery_4155  response regulator receiver sensor signal transduction histidine kinase  42.64 
 
 		 440 aa  109  6e-23  Trichodesmium erythraeum IMS101  Bacteria  normal  0.50715  normal  1 
 
 
-
 
NC_011726  PCC8801_2041  response regulator receiver modulated diguanylate cyclase  41.88 
 
 		 317 aa  108  7.000000000000001e-23  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_2067  response regulator receiver modulated diguanylate cyclase  41.88 
 
 		 317 aa  108  7.000000000000001e-23  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009654  Mmwyl1_2382  response regulator receiver modulated metal dependent phosphohydrolase  33.85 
 
 		 359 aa  108  1e-22  Marinomonas sp. MWYL1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008345  Sfri_3384  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  37.8 
 
 		 829 aa  108  1e-22  Shewanella frigidimarina NCIMB 400  Bacteria  normal  1  n/a   
 
 
-
 
NC_010571  Oter_3856  response regulator receiver sensor signal transduction histidine kinase  39.46 
 
 		 378 aa  107  2e-22  Opitutus terrae PB90-1  Bacteria  normal  1  normal  0.215089 
 
 
-
 
NC_013440  Hoch_2262  response regulator receiver sensor signal transduction histidine kinase  42.97 
 
 		 406 aa  107  2e-22  Haliangium ochraceum DSM 14365  Bacteria  normal  1  normal  0.146487 
 
 
-
 
NC_008062  Bcen_6528  two component AraC family transcriptional regulator  40.8 
 
 		 271 aa  107  2e-22  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.485144  n/a   
 
 
-
 
NC_008544  Bcen2424_6762  two component AraC family transcriptional regulator  40.8 
 
 		 271 aa  107  2e-22  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  0.295507 
 
 
-
 
NC_011831  Cagg_1006  response regulator receiver modulated diguanylate cyclase  41.18 
 
 		 312 aa  107  3e-22  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013173  Dbac_2998  response regulator receiver protein  37.5 
 
 		 377 aa  107  3e-22  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  1  n/a   
 
 
-
 
NC_010814  Glov_3523  response regulator receiver modulated metal dependent phosphohydrolase  42.06 
 
 		 363 aa  107  3e-22  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_010512  Bcenmc03_6350  two component AraC family transcriptional regulator  40.8 
 
 		 271 aa  107  3e-22  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.787195  normal  0.900493 
 
 
-
 
NC_014248  Aazo_4229  response regulator receiver sensor signal transduction histidine kinase  41.94 
 
 		 383 aa  106  4e-22  'Nostoc azollae' 0708  Bacteria  normal  0.599633  n/a   
 
 
-
 
NC_007796  Mhun_1941  response regulator receiver domain-containing protein  36.96 
 
 		 156 aa  106  6e-22  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_008392  Bamb_6198  two component AraC family transcriptional regulator  39.23 
 
 		 277 aa  105  8e-22  Burkholderia ambifaria AMMD  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007520  Tcr_2179  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  43.1 
 
 		 348 aa  105  9e-22  Thiomicrospira crunogena XCL-2  Bacteria  normal  0.378064  n/a   
 
 
-
 
NC_010814  Glov_2955  response regulator receiver modulated diguanylate cyclase  44.14 
 
 		 308 aa  105  1e-21  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_010557  BamMC406_5929  two component AraC family transcriptional regulator  38.46 
 
 		 277 aa  105  1e-21  Burkholderia ambifaria MC40-6  Bacteria  normal  0.473719  normal  1 
 
 
-
 
NC_011729  PCC7424_2188  response regulator receiver sensor signal transduction histidine kinase  40.48 
 
 		 384 aa  105  1e-21  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.00677544 
 
 
-
 
NC_010571  Oter_3794  response regulator receiver sensor signal transduction histidine kinase  41.46 
 
 		 376 aa  105  1e-21  Opitutus terrae PB90-1  Bacteria  normal  0.0277983  normal  0.543799 
 
 
-
 
NC_014248  Aazo_1477  response regulator receiver modulated diguanylate cyclase  39.02 
 
 		 317 aa  105  1e-21  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_011729  PCC7424_0178  response regulator receiver modulated diguanylate cyclase  36.76 
 
 		 322 aa  105  1e-21  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.895619 
 
 
-
 
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