More than 300 homologs were found in PanDaTox collection
for query gene Tcur_4122 on replicon NC_013510
Organism: Thermomonospora curvata DSM 43183



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013510  Tcur_4122  two component transcriptional regulator, winged helix family  100 
 
 
223 aa  436  1e-121  Thermomonospora curvata DSM 43183  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_1333  response regulator receiver protein  92.31 
 
 
222 aa  410  1e-114  Streptosporangium roseum DSM 43021  Bacteria  normal  0.40527  normal  0.1595 
 
 
-
 
NC_014165  Tbis_0707  winged helix family two component transcriptional regulator  91.4 
 
 
222 aa  407  1e-113  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_007333  Tfu_2549  response regulator receiver  85.97 
 
 
222 aa  377  1e-104  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_3846  two component transcriptional regulator, winged helix family  85.52 
 
 
222 aa  377  1e-104  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_0835  two component transcriptional regulator, winged helix family  77.58 
 
 
222 aa  333  1e-90  Catenulispora acidiphila DSM 44928  Bacteria  normal  hitchhiker  0.0000000540746 
 
 
-
 
NC_012669  Bcav_1155  two component transcriptional regulator, winged helix family  67.98 
 
 
230 aa  288  5.0000000000000004e-77  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.560017  normal 
 
 
-
 
NC_013172  Bfae_21090  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  66.67 
 
 
231 aa  287  9e-77  Brachybacterium faecium DSM 4810  Bacteria  normal  0.664911  n/a   
 
 
-
 
NC_013530  Xcel_2599  two component transcriptional regulator, winged helix family  67.4 
 
 
227 aa  286  2e-76  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_014151  Cfla_2389  two component transcriptional regulator, winged helix family  66.96 
 
 
240 aa  285  4e-76  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0687652  decreased coverage  0.0000973314 
 
 
-
 
NC_013521  Sked_08510  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  66.67 
 
 
227 aa  285  5.999999999999999e-76  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.103906  normal  0.575645 
 
 
-
 
NC_013174  Jden_1871  two component transcriptional regulator, winged helix family  67.56 
 
 
226 aa  285  5.999999999999999e-76  Jonesia denitrificans DSM 20603  Bacteria  normal  0.105791  normal  0.266081 
 
 
-
 
NC_013093  Amir_6380  two component transcriptional regulator, winged helix family  65.47 
 
 
223 aa  263  2e-69  Actinosynnema mirum DSM 43827  Bacteria  normal  0.654273  n/a   
 
 
-
 
NC_013169  Ksed_08380  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  63.11 
 
 
244 aa  258  4e-68  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.0276649  normal  0.165598 
 
 
-
 
NC_014158  Tpau_1046  two component transcriptional regulator, winged helix family  56.19 
 
 
230 aa  229  2e-59  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.0213528  n/a   
 
 
-
 
NC_013441  Gbro_1844  response regulator receiver  60.09 
 
 
224 aa  229  3e-59  Gordonia bronchialis DSM 43247  Bacteria  normal  0.0160507  n/a   
 
 
-
 
NC_013159  Svir_05980  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  59.47 
 
 
230 aa  218  5e-56  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal  0.553702 
 
 
-
 
NC_013235  Namu_4223  two component transcriptional regulator, winged helix family  57.14 
 
 
226 aa  217  8.999999999999998e-56  Nakamurella multipartita DSM 44233  Bacteria  decreased coverage  0.000102305  normal  0.0938221 
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  50.66 
 
 
236 aa  214  5.9999999999999996e-55  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_009523  RoseRS_3818  two component transcriptional regulator  49.34 
 
 
230 aa  212  2.9999999999999995e-54  Roseiflexus sp. RS-1  Bacteria  normal  0.386967  normal  0.165932 
 
 
-
 
NC_009767  Rcas_0997  two component transcriptional regulator  48.67 
 
 
230 aa  207  1e-52  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.679101  normal 
 
 
-
 
NC_008699  Noca_1240  response regulator receiver  51.34 
 
 
234 aa  204  6e-52  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_013235  Namu_4929  two component transcriptional regulator, winged helix family  46.02 
 
 
226 aa  203  2e-51  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  46.29 
 
 
229 aa  200  9.999999999999999e-51  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  49.56 
 
 
226 aa  200  9.999999999999999e-51  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  48.47 
 
 
229 aa  201  9.999999999999999e-51  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  47.79 
 
 
231 aa  199  1.9999999999999998e-50  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013757  Gobs_4602  two component transcriptional regulator, winged helix family  47.35 
 
 
226 aa  199  3.9999999999999996e-50  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_2910  response regulator receiver  47.35 
 
 
230 aa  198  5e-50  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  46.46 
 
 
226 aa  198  5e-50  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_013093  Amir_6749  two component transcriptional regulator, winged helix family  45.13 
 
 
226 aa  198  5e-50  Actinosynnema mirum DSM 43827  Bacteria  normal  0.290774  n/a   
 
 
-
 
NC_008726  Mvan_0831  two component transcriptional regulator  46.49 
 
 
228 aa  198  6e-50  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.310785  normal 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  47.35 
 
 
229 aa  197  7.999999999999999e-50  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_011898  Ccel_2106  two component transcriptional regulator, winged helix family  41.52 
 
 
238 aa  197  1.0000000000000001e-49  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_008146  Mmcs_0661  two component transcriptional regulator  45.61 
 
 
228 aa  196  3e-49  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  43.72 
 
 
239 aa  196  3e-49  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_008705  Mkms_0674  two component transcriptional regulator  45.61 
 
 
228 aa  196  3e-49  Mycobacterium sp. KMS  Bacteria  normal  normal  0.850641 
 
 
-
 
NC_009077  Mjls_0654  two component transcriptional regulator  45.61 
 
 
228 aa  196  3e-49  Mycobacterium sp. JLS  Bacteria  normal  normal  0.682961 
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  46.02 
 
 
226 aa  195  5.000000000000001e-49  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  44.93 
 
 
236 aa  194  7e-49  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_009338  Mflv_0082  two component transcriptional regulator  45.18 
 
 
228 aa  194  7e-49  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_011661  Dtur_1237  two component transcriptional regulator, winged helix family  42.11 
 
 
232 aa  193  1e-48  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_0896  two component transcriptional regulator, winged helix family  49.56 
 
 
226 aa  194  1e-48  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.232326  hitchhiker  0.00518822 
 
 
-
 
NC_014158  Tpau_0654  two component transcriptional regulator, winged helix family  43.67 
 
 
229 aa  192  2e-48  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.200991  n/a   
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  48.85 
 
 
240 aa  193  2e-48  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_013947  Snas_0580  two component transcriptional regulator, winged helix family  45.13 
 
 
226 aa  192  3e-48  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_009565  TBFG_10499  two component system sensor transduction protein regX3  44.93 
 
 
227 aa  192  3e-48  Mycobacterium tuberculosis F11  Bacteria  decreased coverage  2.46064e-66  normal 
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  48.02 
 
 
228 aa  192  3e-48  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_013172  Bfae_09290  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  44.54 
 
 
229 aa  191  7e-48  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_010816  BLD_1073  putative response regulator  41.56 
 
 
234 aa  191  7e-48  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_0188  two component transcriptional regulator  45.37 
 
 
245 aa  190  1e-47  Roseiflexus sp. RS-1  Bacteria  hitchhiker  0.00347389  normal  0.0545477 
 
 
-
 
NC_013441  Gbro_0997  response regulator receiver  44.3 
 
 
228 aa  190  1e-47  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_4046  response regulator receiver  45.33 
 
 
225 aa  191  1e-47  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1487  two component transcriptional regulator, winged helix family  41.41 
 
 
232 aa  191  1e-47  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.487145  n/a   
 
 
-
 
NC_013595  Sros_2839  response regulator receiver protein  46.88 
 
 
228 aa  189  2e-47  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0400316  normal  0.0390199 
 
 
-
 
NC_002936  DET0135  DNA-binding response regulator  44.69 
 
 
230 aa  189  2.9999999999999997e-47  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_0724  two component transcriptional regulator  46.02 
 
 
226 aa  189  4e-47  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_0984  two component transcriptional regulator, winged helix family  40.74 
 
 
246 aa  189  4e-47  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.0723779 
 
 
-
 
NC_013124  Afer_0200  two component transcriptional regulator, winged helix family  44.93 
 
 
242 aa  189  4e-47  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  0.0955644  n/a   
 
 
-
 
NC_007777  Francci3_0471  two component transcriptional regulator  46.02 
 
 
226 aa  188  5e-47  Frankia sp. CcI3  Bacteria  normal  normal  0.734397 
 
 
-
 
NC_010001  Cphy_0015  two component transcriptional regulator  43.3 
 
 
228 aa  188  5.999999999999999e-47  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_0264  two component transcriptional regulator  41.15 
 
 
238 aa  187  1e-46  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.392693  n/a   
 
 
-
 
NC_013595  Sros_5447  response regulator receiver protein  47.77 
 
 
228 aa  187  1e-46  Streptosporangium roseum DSM 43021  Bacteria  hitchhiker  0.00883739  normal  0.15212 
 
 
-
 
NC_013441  Gbro_2604  response regulator receiver  44.64 
 
 
244 aa  186  2e-46  Gordonia bronchialis DSM 43247  Bacteria  normal  0.88392  n/a   
 
 
-
 
NC_013169  Ksed_03700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  45.58 
 
 
226 aa  186  2e-46  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.132847 
 
 
-
 
NC_013441  Gbro_4233  response regulator receiver  44.64 
 
 
244 aa  186  2e-46  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP1256  alkaline phosphatase synthesis transcriptional regulatory protein PhoP  42.61 
 
 
236 aa  186  3e-46  Staphylococcus epidermidis RP62A  Bacteria  normal  0.577358  n/a   
 
 
-
 
NC_009921  Franean1_6145  two component transcriptional regulator  46.46 
 
 
228 aa  186  3e-46  Frankia sp. EAN1pec  Bacteria  normal  normal  0.788201 
 
 
-
 
NC_008578  Acel_1606  two component transcriptional regulator  47.73 
 
 
230 aa  186  3e-46  Acidothermus cellulolyticus 11B  Bacteria  normal  0.307098  normal  0.688459 
 
 
-
 
NC_008819  NATL1_11471  two-component response regulator, phosphate  41.3 
 
 
245 aa  186  3e-46  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal  0.0202491 
 
 
-
 
NC_007413  Ava_3369  two component transcriptional regulator  44.16 
 
 
250 aa  185  4e-46  Anabaena variabilis ATCC 29413  Bacteria  normal  0.881494  normal  0.845013 
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  45.92 
 
 
233 aa  185  4e-46  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_2625  two component transcriptional regulator  46.58 
 
 
231 aa  185  4e-46  Roseiflexus sp. RS-1  Bacteria  normal  0.983258  normal 
 
 
-
 
NC_007335  PMN2A_0436  two component transcriptional regulator  40.87 
 
 
245 aa  185  5e-46  Prochlorococcus marinus str. NATL2A  Bacteria  normal  0.18923  n/a   
 
 
-
 
NC_009767  Rcas_4351  two component transcriptional regulator  44.05 
 
 
245 aa  184  8e-46  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.110039  normal 
 
 
-
 
NC_013501  Rmar_0987  two component transcriptional regulator, winged helix family  46.7 
 
 
233 aa  184  8e-46  Rhodothermus marinus DSM 4252  Bacteria  normal  0.195539  n/a   
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  43.56 
 
 
256 aa  184  8e-46  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_011886  Achl_0850  two component transcriptional regulator, winged helix family  45.58 
 
 
226 aa  184  8e-46  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_007333  Tfu_0343  response regulator receiver  46.64 
 
 
232 aa  183  2.0000000000000003e-45  Thermobifida fusca YX  Bacteria  normal  0.86362  n/a   
 
 
-
 
NC_008261  CPF_0623  DNA-binding response regulator  43.05 
 
 
231 aa  183  2.0000000000000003e-45  Clostridium perfringens ATCC 13124  Bacteria  hitchhiker  0.000212568  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  42.22 
 
 
234 aa  183  2.0000000000000003e-45  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_009455  DehaBAV1_0235  two component transcriptional regulator  42.92 
 
 
230 aa  182  3e-45  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  46.15 
 
 
225 aa  182  3e-45  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_007604  Synpcc7942_1012  two component transcriptional regulator  42.49 
 
 
257 aa  182  4.0000000000000006e-45  Synechococcus elongatus PCC 7942  Bacteria  normal  0.658807  normal 
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  43.42 
 
 
226 aa  182  4.0000000000000006e-45  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_009012  Cthe_1394  two component transcriptional regulator  39.29 
 
 
236 aa  182  4.0000000000000006e-45  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000024965  n/a   
 
 
-
 
NC_007577  PMT9312_0717  two component transcriptional regulator  40.43 
 
 
242 aa  182  5.0000000000000004e-45  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  n/a   
 
 
-
 
NC_009091  P9301_12431  two-component response regulator, phosphate  40.43 
 
 
242 aa  181  7e-45  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  0.15803  n/a   
 
 
-
 
NC_008262  CPR_0609  DNA-binding response regulator  42.6 
 
 
231 aa  181  8.000000000000001e-45  Clostridium perfringens SM101  Bacteria  hitchhiker  0.0000282114  n/a   
 
 
-
 
NC_013159  Svir_31270  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  43.36 
 
 
221 aa  181  8.000000000000001e-45  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.014564  normal  0.249814 
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  42.92 
 
 
235 aa  181  9.000000000000001e-45  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_014248  Aazo_2741  winged helix family two component transcriptional regulator  41.56 
 
 
250 aa  181  9.000000000000001e-45  'Nostoc azollae' 0708  Bacteria  normal  0.0957275  n/a   
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  41.85 
 
 
234 aa  181  1e-44  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_006274  BCZK0258  response regulator  40.71 
 
 
237 aa  181  1e-44  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_3600  two component transcriptional regulator, winged helix family  41.92 
 
 
250 aa  181  1e-44  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.00284005 
 
 
-
 
NC_009380  Strop_0337  two component transcriptional regulator  47.14 
 
 
227 aa  181  1e-44  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  39.91 
 
 
239 aa  180  1e-44  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  41.85 
 
 
234 aa  181  1e-44  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  39.91 
 
 
239 aa  180  1e-44  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_013739  Cwoe_5905  two component transcriptional regulator, winged helix family  43.48 
 
 
237 aa  180  2e-44  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
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