More than 300 homologs were found in PanDaTox collection
for query gene Mchl_4480 on replicon NC_011757
Organism: Methylobacterium chloromethanicum CM4



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011757  Mchl_4480  response regulator receiver protein  100 
 
 
128 aa  251  2.0000000000000002e-66  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.361856  normal 
 
 
-
 
NC_010172  Mext_4112  response regulator receiver  100 
 
 
128 aa  251  2.0000000000000002e-66  Methylobacterium extorquens PA1  Bacteria  normal  0.576276  normal  0.834365 
 
 
-
 
NC_010725  Mpop_4593  response regulator receiver protein  83.72 
 
 
129 aa  204  3e-52  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_0516  response regulator receiver protein  66.39 
 
 
124 aa  134  4e-31  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.131947  normal 
 
 
-
 
NC_010172  Mext_3363  response regulator receiver  60.18 
 
 
126 aa  131  3.9999999999999996e-30  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_6418  response regulator receiver protein  60.5 
 
 
126 aa  130  9e-30  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0095  response regulator receiver protein  61.79 
 
 
123 aa  129  2.0000000000000002e-29  Methylobacterium populi BJ001  Bacteria  normal  0.898425  normal 
 
 
-
 
NC_010511  M446_4214  response regulator receiver protein  55.2 
 
 
130 aa  127  5.0000000000000004e-29  Methylobacterium sp. 4-46  Bacteria  normal  0.843954  normal  0.213428 
 
 
-
 
NC_010172  Mext_1895  response regulator receiver  61.06 
 
 
126 aa  125  2.0000000000000002e-28  Methylobacterium extorquens PA1  Bacteria  normal  0.208302  normal 
 
 
-
 
NC_010725  Mpop_1475  response regulator receiver protein  52.85 
 
 
124 aa  124  4.0000000000000003e-28  Methylobacterium populi BJ001  Bacteria  normal  0.292646  normal  0.101486 
 
 
-
 
NC_011004  Rpal_1668  response regulator receiver protein  55.08 
 
 
131 aa  118  3e-26  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007778  RPB_4041  response regulator receiver domain-containing protein  53.91 
 
 
124 aa  117  7e-26  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0979956  normal 
 
 
-
 
NC_007958  RPD_3796  response regulator receiver  52.25 
 
 
124 aa  107  7.000000000000001e-23  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.787937 
 
 
-
 
NC_011894  Mnod_4811  response regulator receiver protein  48.87 
 
 
140 aa  102  2e-21  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_007958  RPD_0328  response regulator receiver  48.65 
 
 
147 aa  101  3e-21  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.0634669  normal 
 
 
-
 
NC_011666  Msil_0850  response regulator receiver protein  51.38 
 
 
131 aa  100  8e-21  Methylocella silvestris BL2  Bacteria  n/a    normal  0.886181 
 
 
-
 
NC_007778  RPB_0497  response regulator receiver domain-containing protein  49.56 
 
 
125 aa  99.4  2e-20  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0614776  normal 
 
 
-
 
NC_007925  RPC_1228  response regulator receiver domain-containing protein  53.4 
 
 
124 aa  99.4  2e-20  Rhodopseudomonas palustris BisB18  Bacteria  normal  hitchhiker  0.0000969205 
 
 
-
 
NC_009511  Swit_4398  response regulator receiver protein  54.46 
 
 
127 aa  97.8  4e-20  Sphingomonas wittichii RW1  Bacteria  normal  0.481257  normal 
 
 
-
 
NC_011004  Rpal_4537  response regulator receiver protein  50 
 
 
125 aa  97.4  5e-20  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_2634  response regulator receiver protein  53.1 
 
 
135 aa  97.1  8e-20  Methylobacterium sp. 4-46  Bacteria  normal  0.873964  normal  0.0480327 
 
 
-
 
NC_011984  Avi_9028  two component sensor kinase/response regulator hybrid  43.36 
 
 
123 aa  95.9  2e-19  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_012850  Rleg_2931  response regulator receiver protein  46.85 
 
 
122 aa  94  7e-19  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.139057  normal 
 
 
-
 
NC_011757  Mchl_4665  response regulator receiver protein  42.61 
 
 
127 aa  94  7e-19  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.191751 
 
 
-
 
NC_012853  Rleg_5645  response regulator receiver protein  45.9 
 
 
182 aa  92.4  2e-18  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.633042  normal 
 
 
-
 
NC_011666  Msil_3741  response regulator receiver protein  45.38 
 
 
127 aa  92.4  2e-18  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_010505  Mrad2831_0691  response regulator receiver protein  47.86 
 
 
128 aa  92.4  2e-18  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.852187  normal  0.378672 
 
 
-
 
NC_011369  Rleg2_2670  response regulator receiver protein  44.55 
 
 
122 aa  91.3  5e-18  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.313891  normal 
 
 
-
 
NC_010725  Mpop_4814  response regulator receiver protein  43.36 
 
 
127 aa  90.9  5e-18  Methylobacterium populi BJ001  Bacteria  normal  0.24379  normal  0.163877 
 
 
-
 
NC_010725  Mpop_3346  response regulator receiver protein  45.76 
 
 
128 aa  90.5  7e-18  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_3474  response regulator receiver protein  45.76 
 
 
128 aa  90.1  8e-18  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.212338  normal 
 
 
-
 
NC_010172  Mext_3150  response regulator receiver  45.76 
 
 
128 aa  90.1  8e-18  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_0144  hypothetical protein  56.18 
 
 
118 aa  90.1  9e-18  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011365  Gdia_2320  response regulator receiver protein  45.13 
 
 
127 aa  89.7  1e-17  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  normal  0.632565 
 
 
-
 
NC_012858  Rleg_6937  response regulator receiver protein  50 
 
 
133 aa  89.7  1e-17  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0671376  normal 
 
 
-
 
NC_009507  Swit_5396  response regulator receiver protein  45 
 
 
132 aa  89.4  2e-17  Sphingomonas wittichii RW1  Bacteria  normal  0.476573  normal 
 
 
-
 
NC_010505  Mrad2831_2499  response regulator receiver protein  42.86 
 
 
136 aa  85.1  3e-16  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.353166  normal 
 
 
-
 
NC_010172  Mext_4296  response regulator receiver  40 
 
 
115 aa  85.1  3e-16  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010510  Mrad2831_5790  response regulator receiver protein  49.14 
 
 
122 aa  84.7  4e-16  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.0889979  normal  0.112489 
 
 
-
 
NC_007778  RPB_2945  response regulator receiver domain-containing protein  38.74 
 
 
124 aa  84.7  4e-16  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.161273  normal  0.393497 
 
 
-
 
NC_010505  Mrad2831_2732  response regulator receiver protein  38.1 
 
 
151 aa  83.6  9e-16  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.169998 
 
 
-
 
NC_012850  Rleg_0771  response regulator receiver protein  40.18 
 
 
130 aa  83.2  0.000000000000001  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_011989  Avi_1195  Two component sensor kinase/response regulator hybrid protein  40.35 
 
 
130 aa  83.2  0.000000000000001  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_5535  response regulator receiver protein  45.54 
 
 
130 aa  81.6  0.000000000000003  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.591914  decreased coverage  0.00892468 
 
 
-
 
NC_009485  BBta_7425  putative response regulator receiver (CheY-like protein)  41.96 
 
 
133 aa  79  0.00000000000002  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.0404716 
 
 
-
 
NC_010725  Mpop_5091  response regulator receiver protein  39.84 
 
 
134 aa  78.2  0.00000000000003  Methylobacterium populi BJ001  Bacteria  normal  0.947919  normal 
 
 
-
 
NC_010172  Mext_4573  response regulator receiver  39.66 
 
 
134 aa  77.8  0.00000000000004  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.546072 
 
 
-
 
NC_011757  Mchl_5033  response regulator receiver protein  39.66 
 
 
134 aa  77.8  0.00000000000004  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.649741  normal  0.0493927 
 
 
-
 
NC_011666  Msil_2794  response regulator receiver protein  43.86 
 
 
125 aa  78.2  0.00000000000004  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_007958  RPD_2510  response regulator receiver  38.39 
 
 
124 aa  76.6  0.0000000000001  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.294916 
 
 
-
 
NC_011894  Mnod_7165  response regulator receiver protein  35.71 
 
 
143 aa  75.9  0.0000000000002  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.272897  n/a   
 
 
-
 
NC_011894  Mnod_7092  response regulator receiver protein  40.71 
 
 
196 aa  75.5  0.0000000000002  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.08524  n/a   
 
 
-
 
NC_011757  Mchl_0091  response regulator receiver protein  41.07 
 
 
124 aa  75.9  0.0000000000002  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.589534  normal 
 
 
-
 
NC_011894  Mnod_6162  PAS/PAC sensor hybrid histidine kinase  44.64 
 
 
673 aa  75.1  0.0000000000003  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.30079  n/a   
 
 
-
 
NC_010511  M446_6212  response regulator receiver protein  40.71 
 
 
177 aa  74.7  0.0000000000004  Methylobacterium sp. 4-46  Bacteria  normal  0.0392664  normal  0.598992 
 
 
-
 
NC_011894  Mnod_0073  response regulator receiver protein  40.18 
 
 
128 aa  74.3  0.0000000000006  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_6328  response regulator receiver protein  35.71 
 
 
141 aa  74.3  0.0000000000006  Methylobacterium sp. 4-46  Bacteria  normal  hitchhiker  0.00633094 
 
 
-
 
NC_010172  Mext_1672  PAS sensor protein  34.56 
 
 
695 aa  73.9  0.0000000000007  Methylobacterium extorquens PA1  Bacteria  normal  0.487392  normal 
 
 
-
 
NC_011368  Rleg2_5228  response regulator receiver protein  39.25 
 
 
135 aa  73.2  0.000000000001  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.0214459  normal  0.509013 
 
 
-
 
NC_011757  Mchl_1990  multi-sensor hybrid histidine kinase  33.83 
 
 
695 aa  72  0.000000000002  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_5605  response regulator receiver protein  40.52 
 
 
198 aa  72.4  0.000000000002  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.469743  normal 
 
 
-
 
NC_007925  RPC_3132  PAS/PAC sensor hybrid histidine kinase  41.53 
 
 
743 aa  72.4  0.000000000002  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.583735  normal 
 
 
-
 
NC_010172  Mext_1882  response regulator receiver  42.42 
 
 
108 aa  72.4  0.000000000002  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011369  Rleg2_1658  PAS/PAC sensor hybrid histidine kinase  44.12 
 
 
1036 aa  71.6  0.000000000003  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.705021 
 
 
-
 
NC_009485  BBta_0880  histidine kinase  38.46 
 
 
534 aa  72  0.000000000003  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_2780  response regulator receiver protein  41.59 
 
 
173 aa  70.9  0.000000000005  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_012853  Rleg_5650  response regulator receiver protein  41.23 
 
 
128 aa  70.5  0.000000000007  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.343299  normal  0.64647 
 
 
-
 
NC_010172  Mext_2557  response regulator receiver  41.59 
 
 
194 aa  70.5  0.000000000008  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_1735  response regulator receiver protein  38.6 
 
 
119 aa  70.5  0.000000000008  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.419682 
 
 
-
 
NC_011757  Mchl_3366  histidine kinase  38.39 
 
 
580 aa  69.7  0.00000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_4788  histidine kinase  38.39 
 
 
685 aa  69.7  0.00000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_1503  response regulator receiver protein  39.17 
 
 
130 aa  70.1  0.00000000001  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.156189  n/a   
 
 
-
 
NC_011368  Rleg2_4740  response regulator receiver protein  40.2 
 
 
126 aa  69.3  0.00000000002  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_011145  AnaeK_2898  response regulator receiver protein  43.59 
 
 
119 aa  69.3  0.00000000002  Anaeromyxobacter sp. K  Bacteria  normal  0.19582  n/a   
 
 
-
 
NC_010511  M446_6442  multi-sensor hybrid histidine kinase  37.61 
 
 
688 aa  68.9  0.00000000002  Methylobacterium sp. 4-46  Bacteria  normal  0.381857  normal 
 
 
-
 
NC_010505  Mrad2831_3211  PAS/PAC sensor hybrid histidine kinase  36.94 
 
 
696 aa  68.6  0.00000000003  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.7085  normal 
 
 
-
 
NC_008391  Bamb_4524  PAS/PAC sensor hybrid histidine kinase  41.96 
 
 
589 aa  67.8  0.00000000004  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010338  Caul_3549  multi-sensor hybrid histidine kinase  40.71 
 
 
702 aa  68.2  0.00000000004  Caulobacter sp. K31  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_2488  response regulator receiver protein  40.35 
 
 
173 aa  67.8  0.00000000005  Methylobacterium populi BJ001  Bacteria  normal  0.365206  normal  0.13004 
 
 
-
 
NC_010552  BamMC406_5047  PAS/PAC sensor hybrid histidine kinase  41.07 
 
 
589 aa  67.4  0.00000000007  Burkholderia ambifaria MC40-6  Bacteria  normal  0.153925  normal 
 
 
-
 
NC_010511  M446_3963  response regulator receiver protein  38.14 
 
 
133 aa  67  0.00000000008  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.150847 
 
 
-
 
NC_010676  Bphyt_5841  PAS/PAC sensor hybrid histidine kinase  38.28 
 
 
887 aa  67  0.00000000009  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.111175 
 
 
-
 
NC_004578  PSPTO_4293  sensory box histidine kinase/response regulator  37.93 
 
 
793 aa  66.6  0.0000000001  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_0810  response regulator receiver protein  34.13 
 
 
132 aa  66.6  0.0000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.316292 
 
 
-
 
NC_007643  Rru_A2820  multi-sensor hybrid histidine kinase / cell cycle control histidine kinase CckA  40.54 
 
 
829 aa  66.2  0.0000000001  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_010172  Mext_0851  response regulator receiver  34.13 
 
 
132 aa  66.6  0.0000000001  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.234035 
 
 
-
 
NC_007778  RPB_3818  PAS/PAC sensor hybrid histidine kinase  39.2 
 
 
1426 aa  66.2  0.0000000001  Rhodopseudomonas palustris HaA2  Bacteria  normal  normal 
 
 
-
 
NC_007958  RPD_1666  ATP-binding region, ATPase-like  39.47 
 
 
1427 aa  66.6  0.0000000001  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.207779 
 
 
-
 
NC_011891  A2cp1_2989  response regulator receiver protein  41.88 
 
 
119 aa  66.6  0.0000000001  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_2071  response regulator receiver protein  38.79 
 
 
124 aa  66.2  0.0000000001  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_008783  BARBAKC583_0853  sensor histidine kinase/reponse regulator  36.36 
 
 
845 aa  66.6  0.0000000001  Bartonella bacilliformis KC583  Bacteria  decreased coverage  0.00134282  n/a   
 
 
-
 
NC_010511  M446_0675  response regulator receiver protein  37.29 
 
 
129 aa  66.6  0.0000000001  Methylobacterium sp. 4-46  Bacteria  normal  0.410105  normal 
 
 
-
 
NC_009523  RoseRS_4039  multi-sensor hybrid histidine kinase  41.23 
 
 
1039 aa  66.6  0.0000000001  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0775  response regulator receiver protein  33.33 
 
 
132 aa  65.5  0.0000000002  Methylobacterium populi BJ001  Bacteria  normal  normal  0.0313977 
 
 
-
 
NC_011831  Cagg_0388  multi-sensor hybrid histidine kinase  36.04 
 
 
793 aa  65.5  0.0000000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_1889  ATPase domain-containing protein  36.75 
 
 
280 aa  66.2  0.0000000002  Methylobacterium extorquens PA1  Bacteria  normal  0.508337  normal 
 
 
-
 
NC_007760  Adeh_2803  response regulator receiver domain-containing protein  42.74 
 
 
119 aa  65.5  0.0000000002  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.233301  n/a   
 
 
-
 
NC_011894  Mnod_3607  response regulator receiver protein  36.21 
 
 
135 aa  65.5  0.0000000002  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.621989  n/a   
 
 
-
 
NC_010725  Mpop_0171  multi-sensor hybrid histidine kinase  36.75 
 
 
740 aa  65.5  0.0000000002  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_4235  sensor histidine kinase  36.07 
 
 
754 aa  65.5  0.0000000002  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.507157  normal  0.848747 
 
 
-
 
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