More than 300 homologs were found in PanDaTox collection
for query gene M446_6418 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010511  M446_6418  response regulator receiver protein  100 
 
 
126 aa  255  2e-67  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_1895  response regulator receiver  74.8 
 
 
126 aa  183  6e-46  Methylobacterium extorquens PA1  Bacteria  normal  0.208302  normal 
 
 
-
 
NC_010172  Mext_3363  response regulator receiver  77.59 
 
 
126 aa  181  3e-45  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_4214  response regulator receiver protein  66.12 
 
 
130 aa  164  5e-40  Methylobacterium sp. 4-46  Bacteria  normal  0.843954  normal  0.213428 
 
 
-
 
NC_010725  Mpop_1475  response regulator receiver protein  58.68 
 
 
124 aa  143  9e-34  Methylobacterium populi BJ001  Bacteria  normal  0.292646  normal  0.101486 
 
 
-
 
NC_011757  Mchl_0516  response regulator receiver protein  62.5 
 
 
124 aa  136  8.999999999999999e-32  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.131947  normal 
 
 
-
 
NC_010172  Mext_0144  hypothetical protein  72.73 
 
 
118 aa  132  1.9999999999999998e-30  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_4593  response regulator receiver protein  60.17 
 
 
129 aa  131  3e-30  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0095  response regulator receiver protein  55.83 
 
 
123 aa  131  3.9999999999999996e-30  Methylobacterium populi BJ001  Bacteria  normal  0.898425  normal 
 
 
-
 
NC_007778  RPB_4041  response regulator receiver domain-containing protein  60.95 
 
 
124 aa  130  6.999999999999999e-30  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0979956  normal 
 
 
-
 
NC_011757  Mchl_4480  response regulator receiver protein  60.5 
 
 
128 aa  130  9e-30  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.361856  normal 
 
 
-
 
NC_010172  Mext_4112  response regulator receiver  60.5 
 
 
128 aa  130  9e-30  Methylobacterium extorquens PA1  Bacteria  normal  0.576276  normal  0.834365 
 
 
-
 
NC_007958  RPD_3796  response regulator receiver  56.88 
 
 
124 aa  128  3e-29  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.787937 
 
 
-
 
NC_011004  Rpal_1668  response regulator receiver protein  59.05 
 
 
131 aa  124  3e-28  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007925  RPC_1228  response regulator receiver domain-containing protein  57.14 
 
 
124 aa  114  3e-25  Rhodopseudomonas palustris BisB18  Bacteria  normal  hitchhiker  0.0000969205 
 
 
-
 
NC_011666  Msil_0850  response regulator receiver protein  56 
 
 
131 aa  114  3.9999999999999997e-25  Methylocella silvestris BL2  Bacteria  n/a    normal  0.886181 
 
 
-
 
NC_011666  Msil_3741  response regulator receiver protein  53.15 
 
 
127 aa  114  3.9999999999999997e-25  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_010505  Mrad2831_0691  response regulator receiver protein  49.55 
 
 
128 aa  112  2.0000000000000002e-24  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.852187  normal  0.378672 
 
 
-
 
NC_009511  Swit_4398  response regulator receiver protein  53.92 
 
 
127 aa  110  7.000000000000001e-24  Sphingomonas wittichii RW1  Bacteria  normal  0.481257  normal 
 
 
-
 
NC_007958  RPD_0328  response regulator receiver  46.22 
 
 
147 aa  107  6e-23  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.0634669  normal 
 
 
-
 
NC_011004  Rpal_4537  response regulator receiver protein  50.46 
 
 
125 aa  107  7.000000000000001e-23  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_3346  response regulator receiver protein  49.55 
 
 
128 aa  105  3e-22  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_3150  response regulator receiver  48.65 
 
 
128 aa  105  3e-22  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_3474  response regulator receiver protein  48.65 
 
 
128 aa  105  3e-22  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.212338  normal 
 
 
-
 
NC_011984  Avi_9028  two component sensor kinase/response regulator hybrid  45.54 
 
 
123 aa  103  6e-22  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011894  Mnod_4811  response regulator receiver protein  45.05 
 
 
140 aa  103  8e-22  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_012850  Rleg_2931  response regulator receiver protein  45.61 
 
 
122 aa  103  1e-21  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.139057  normal 
 
 
-
 
NC_011369  Rleg2_2670  response regulator receiver protein  44.74 
 
 
122 aa  102  1e-21  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.313891  normal 
 
 
-
 
NC_007778  RPB_0497  response regulator receiver domain-containing protein  47.41 
 
 
125 aa  102  1e-21  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0614776  normal 
 
 
-
 
NC_007778  RPB_2945  response regulator receiver domain-containing protein  41.28 
 
 
124 aa  101  4e-21  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.161273  normal  0.393497 
 
 
-
 
NC_012850  Rleg_0771  response regulator receiver protein  44.04 
 
 
130 aa  99.4  1e-20  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_2634  response regulator receiver protein  43.1 
 
 
135 aa  99.4  2e-20  Methylobacterium sp. 4-46  Bacteria  normal  0.873964  normal  0.0480327 
 
 
-
 
NC_011989  Avi_1195  Two component sensor kinase/response regulator hybrid protein  41.44 
 
 
130 aa  99  2e-20  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011666  Msil_2794  response regulator receiver protein  45.95 
 
 
125 aa  97.4  6e-20  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_010725  Mpop_4814  response regulator receiver protein  46.09 
 
 
127 aa  97.1  7e-20  Methylobacterium populi BJ001  Bacteria  normal  0.24379  normal  0.163877 
 
 
-
 
NC_012853  Rleg_5645  response regulator receiver protein  44.74 
 
 
182 aa  96.7  1e-19  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.633042  normal 
 
 
-
 
NC_010505  Mrad2831_2499  response regulator receiver protein  48.57 
 
 
136 aa  95.1  3e-19  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.353166  normal 
 
 
-
 
NC_011757  Mchl_4665  response regulator receiver protein  42.48 
 
 
127 aa  95.1  3e-19  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.191751 
 
 
-
 
NC_007958  RPD_2510  response regulator receiver  38.74 
 
 
124 aa  93.6  8e-19  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.294916 
 
 
-
 
NC_010172  Mext_4573  response regulator receiver  43.36 
 
 
134 aa  92  3e-18  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.546072 
 
 
-
 
NC_010725  Mpop_5091  response regulator receiver protein  43.36 
 
 
134 aa  91.7  3e-18  Methylobacterium populi BJ001  Bacteria  normal  0.947919  normal 
 
 
-
 
NC_010505  Mrad2831_2732  response regulator receiver protein  41.59 
 
 
151 aa  92  3e-18  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.169998 
 
 
-
 
NC_011757  Mchl_5033  response regulator receiver protein  43.36 
 
 
134 aa  92  3e-18  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.649741  normal  0.0493927 
 
 
-
 
NC_009507  Swit_5396  response regulator receiver protein  41.96 
 
 
132 aa  90.9  5e-18  Sphingomonas wittichii RW1  Bacteria  normal  0.476573  normal 
 
 
-
 
NC_011365  Gdia_2320  response regulator receiver protein  43.12 
 
 
127 aa  89.4  1e-17  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  normal  0.632565 
 
 
-
 
NC_010172  Mext_4296  response regulator receiver  40.37 
 
 
115 aa  89.4  2e-17  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_1882  response regulator receiver  45.1 
 
 
108 aa  89  2e-17  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_0864  response regulator receiver protein  40.54 
 
 
129 aa  89  2e-17  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  hitchhiker  0.00632773 
 
 
-
 
NC_010511  M446_3963  response regulator receiver protein  43.12 
 
 
133 aa  87.4  5e-17  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.150847 
 
 
-
 
NC_011894  Mnod_3607  response regulator receiver protein  44.34 
 
 
135 aa  87.4  5e-17  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.621989  n/a   
 
 
-
 
NC_009485  BBta_7425  putative response regulator receiver (CheY-like protein)  42.61 
 
 
133 aa  86.7  9e-17  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.0404716 
 
 
-
 
NC_012858  Rleg_6937  response regulator receiver protein  42.71 
 
 
133 aa  86.3  1e-16  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0671376  normal 
 
 
-
 
NC_010505  Mrad2831_5535  response regulator receiver protein  43.97 
 
 
130 aa  85.9  2e-16  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.591914  decreased coverage  0.00892468 
 
 
-
 
NC_011369  Rleg2_1201  integral membrane sensor hybrid histidine kinase  43.22 
 
 
548 aa  85.9  2e-16  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.642458  normal 
 
 
-
 
NC_011894  Mnod_7165  response regulator receiver protein  38.94 
 
 
143 aa  85.5  2e-16  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.272897  n/a   
 
 
-
 
NC_010511  M446_6328  response regulator receiver protein  38.94 
 
 
141 aa  85.1  3e-16  Methylobacterium sp. 4-46  Bacteria  normal  hitchhiker  0.00633094 
 
 
-
 
NC_012850  Rleg_1290  histidine kinase  43.22 
 
 
573 aa  83.6  0.000000000000001  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.163396  normal 
 
 
-
 
NC_010511  M446_6212  response regulator receiver protein  38.52 
 
 
177 aa  82  0.000000000000002  Methylobacterium sp. 4-46  Bacteria  normal  0.0392664  normal  0.598992 
 
 
-
 
NC_010725  Mpop_0775  response regulator receiver protein  39.62 
 
 
132 aa  82.8  0.000000000000002  Methylobacterium populi BJ001  Bacteria  normal  normal  0.0313977 
 
 
-
 
NC_011071  Smal_1735  response regulator receiver protein  40.71 
 
 
119 aa  82.4  0.000000000000002  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.419682 
 
 
-
 
NC_011894  Mnod_7092  response regulator receiver protein  40.71 
 
 
196 aa  81.3  0.000000000000004  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.08524  n/a   
 
 
-
 
NC_011369  Rleg2_1658  PAS/PAC sensor hybrid histidine kinase  40.18 
 
 
1036 aa  80.9  0.000000000000005  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.705021 
 
 
-
 
NC_010172  Mext_0851  response regulator receiver  37.74 
 
 
132 aa  80.5  0.000000000000007  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.234035 
 
 
-
 
NC_011757  Mchl_0810  response regulator receiver protein  37.74 
 
 
132 aa  80.5  0.000000000000007  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.316292 
 
 
-
 
NC_011757  Mchl_2780  response regulator receiver protein  41.59 
 
 
173 aa  79.7  0.00000000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_0091  response regulator receiver protein  37.5 
 
 
124 aa  80.1  0.00000000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.589534  normal 
 
 
-
 
NC_010505  Mrad2831_3211  PAS/PAC sensor hybrid histidine kinase  39.32 
 
 
696 aa  79.7  0.00000000000001  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.7085  normal 
 
 
-
 
NC_011368  Rleg2_4740  response regulator receiver protein  39.13 
 
 
126 aa  79  0.00000000000002  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_2488  response regulator receiver protein  40.34 
 
 
173 aa  79  0.00000000000002  Methylobacterium populi BJ001  Bacteria  normal  0.365206  normal  0.13004 
 
 
-
 
NC_011368  Rleg2_5228  response regulator receiver protein  33.64 
 
 
135 aa  79.3  0.00000000000002  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.0214459  normal  0.509013 
 
 
-
 
NC_010172  Mext_2557  response regulator receiver  40.71 
 
 
194 aa  78.6  0.00000000000003  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5841  PAS/PAC sensor hybrid histidine kinase  41.59 
 
 
887 aa  77.8  0.00000000000004  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.111175 
 
 
-
 
NC_007925  RPC_3132  PAS/PAC sensor hybrid histidine kinase  39.66 
 
 
743 aa  77  0.00000000000008  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.583735  normal 
 
 
-
 
NC_010505  Mrad2831_5605  response regulator receiver protein  40 
 
 
198 aa  77  0.00000000000009  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.469743  normal 
 
 
-
 
NC_010172  Mext_3778  response regulator receiver  38.05 
 
 
129 aa  76.6  0.0000000000001  Methylobacterium extorquens PA1  Bacteria  normal  0.0998176  normal 
 
 
-
 
NC_011757  Mchl_4072  response regulator receiver protein  38.05 
 
 
129 aa  76.6  0.0000000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_7844  sensor histidine kinase  38.14 
 
 
529 aa  76.6  0.0000000000001  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.651552 
 
 
-
 
NC_010622  Bphy_0135  multi-sensor hybrid histidine kinase  40.32 
 
 
1631 aa  75.9  0.0000000000002  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B0221  GAF sensor hybrid histidine kinase  42.02 
 
 
1651 aa  75.9  0.0000000000002  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_2071  response regulator receiver protein  40.35 
 
 
124 aa  76.3  0.0000000000002  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_010510  Mrad2831_5790  response regulator receiver protein  38.02 
 
 
122 aa  75.9  0.0000000000002  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.0889979  normal  0.112489 
 
 
-
 
NC_011894  Mnod_0143  response regulator receiver protein  38.14 
 
 
130 aa  75.9  0.0000000000002  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.363881  n/a   
 
 
-
 
NC_010511  M446_6442  multi-sensor hybrid histidine kinase  37.84 
 
 
688 aa  75.9  0.0000000000002  Methylobacterium sp. 4-46  Bacteria  normal  0.381857  normal 
 
 
-
 
NC_011894  Mnod_6162  PAS/PAC sensor hybrid histidine kinase  43.86 
 
 
673 aa  75.9  0.0000000000002  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.30079  n/a   
 
 
-
 
NC_007492  Pfl01_3529  response regulator receiver domain-containing protein  36.22 
 
 
137 aa  75.1  0.0000000000003  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.440569  normal  0.421617 
 
 
-
 
NC_011757  Mchl_1990  multi-sensor hybrid histidine kinase  37.27 
 
 
695 aa  75.1  0.0000000000003  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_1672  PAS sensor protein  37.61 
 
 
695 aa  75.1  0.0000000000003  Methylobacterium extorquens PA1  Bacteria  normal  0.487392  normal 
 
 
-
 
NC_010322  PputGB1_2991  response regulator receiver protein  39.6 
 
 
138 aa  75.1  0.0000000000003  Pseudomonas putida GB-1  Bacteria  normal  normal  0.430733 
 
 
-
 
NC_012853  Rleg_5650  response regulator receiver protein  40.37 
 
 
128 aa  75.1  0.0000000000003  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.343299  normal  0.64647 
 
 
-
 
NC_008783  BARBAKC583_0853  sensor histidine kinase/reponse regulator  41.07 
 
 
845 aa  73.9  0.0000000000008  Bartonella bacilliformis KC583  Bacteria  decreased coverage  0.00134282  n/a   
 
 
-
 
NC_012853  Rleg_5929  response regulator receiver protein  41.75 
 
 
128 aa  73.2  0.000000000001  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_4034  response regulator receiver protein  36.28 
 
 
129 aa  72.8  0.000000000001  Methylobacterium populi BJ001  Bacteria  normal  0.526175  normal 
 
 
-
 
NC_010172  Mext_4170  response regulator receiver  38.26 
 
 
120 aa  73.2  0.000000000001  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_4092  response regulator receiver protein  36.36 
 
 
161 aa  73.2  0.000000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_0861  response regulator receiver protein  42.06 
 
 
135 aa  73.6  0.000000000001  Methylobacterium sp. 4-46  Bacteria  normal  0.0503153  normal 
 
 
-
 
NC_011894  Mnod_0073  response regulator receiver protein  39.29 
 
 
128 aa  73.2  0.000000000001  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_4539  response regulator receiver protein  38.26 
 
 
120 aa  73.2  0.000000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.866024  normal 
 
 
-
 
NC_011988  Avi_5545  two component sensor kinase/response regulator hybrid  38.84 
 
 
1036 aa  73.2  0.000000000001  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_010676  Bphyt_7104  multi-sensor hybrid histidine kinase  39.5 
 
 
1646 aa  72.4  0.000000000002  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0314  response regulator receiver protein  36.7 
 
 
127 aa  72.4  0.000000000002  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
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