More than 300 homologs were found in PanDaTox collection
for query gene M446_3963 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010511  M446_3963  response regulator receiver protein  100 
 
 
133 aa  258  2e-68  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.150847 
 
 
-
 
NC_011894  Mnod_3607  response regulator receiver protein  89.15 
 
 
135 aa  229  1e-59  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.621989  n/a   
 
 
-
 
NC_010172  Mext_0851  response regulator receiver  64 
 
 
132 aa  169  1e-41  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.234035 
 
 
-
 
NC_011757  Mchl_0810  response regulator receiver protein  64 
 
 
132 aa  169  1e-41  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.316292 
 
 
-
 
NC_010725  Mpop_0775  response regulator receiver protein  64 
 
 
132 aa  167  4e-41  Methylobacterium populi BJ001  Bacteria  normal  normal  0.0313977 
 
 
-
 
NC_010505  Mrad2831_0864  response regulator receiver protein  62.2 
 
 
129 aa  167  5e-41  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  hitchhiker  0.00632773 
 
 
-
 
NC_010725  Mpop_3346  response regulator receiver protein  43.65 
 
 
128 aa  102  2e-21  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_3150  response regulator receiver  46.43 
 
 
128 aa  99  2e-20  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_3474  response regulator receiver protein  46.43 
 
 
128 aa  99  2e-20  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.212338  normal 
 
 
-
 
NC_010505  Mrad2831_0691  response regulator receiver protein  40 
 
 
128 aa  97.8  4e-20  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.852187  normal  0.378672 
 
 
-
 
NC_010725  Mpop_1475  response regulator receiver protein  49.02 
 
 
124 aa  93.6  9e-19  Methylobacterium populi BJ001  Bacteria  normal  0.292646  normal  0.101486 
 
 
-
 
NC_011894  Mnod_4811  response regulator receiver protein  40.52 
 
 
140 aa  92.4  2e-18  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_4214  response regulator receiver protein  41.96 
 
 
130 aa  90.1  9e-18  Methylobacterium sp. 4-46  Bacteria  normal  0.843954  normal  0.213428 
 
 
-
 
NC_010172  Mext_1895  response regulator receiver  42.73 
 
 
126 aa  89.4  2e-17  Methylobacterium extorquens PA1  Bacteria  normal  0.208302  normal 
 
 
-
 
NC_007958  RPD_3796  response regulator receiver  41.59 
 
 
124 aa  88.6  3e-17  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.787937 
 
 
-
 
NC_010511  M446_2634  response regulator receiver protein  38.26 
 
 
135 aa  88.6  3e-17  Methylobacterium sp. 4-46  Bacteria  normal  0.873964  normal  0.0480327 
 
 
-
 
NC_010511  M446_6418  response regulator receiver protein  43.12 
 
 
126 aa  87.4  5e-17  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_012850  Rleg_2931  response regulator receiver protein  37.72 
 
 
122 aa  86.7  1e-16  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.139057  normal 
 
 
-
 
NC_011004  Rpal_1668  response regulator receiver protein  40 
 
 
131 aa  85.9  2e-16  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007778  RPB_4041  response regulator receiver domain-containing protein  38.26 
 
 
124 aa  84.3  5e-16  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0979956  normal 
 
 
-
 
NC_011369  Rleg2_2670  response regulator receiver protein  36.84 
 
 
122 aa  83.6  8e-16  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.313891  normal 
 
 
-
 
NC_011666  Msil_3741  response regulator receiver protein  39.13 
 
 
127 aa  83.6  9e-16  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_010172  Mext_3363  response regulator receiver  40 
 
 
126 aa  83.2  0.000000000000001  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_2499  response regulator receiver protein  41.03 
 
 
136 aa  82  0.000000000000002  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.353166  normal 
 
 
-
 
NC_002947  PP_3969  response regulator  33.61 
 
 
120 aa  79.7  0.00000000000001  Pseudomonas putida KT2440  Bacteria  normal  normal  0.13044 
 
 
-
 
NC_007925  RPC_1228  response regulator receiver domain-containing protein  39.42 
 
 
124 aa  79  0.00000000000002  Rhodopseudomonas palustris BisB18  Bacteria  normal  hitchhiker  0.0000969205 
 
 
-
 
NC_011666  Msil_0850  response regulator receiver protein  43.69 
 
 
131 aa  78.2  0.00000000000003  Methylocella silvestris BL2  Bacteria  n/a    normal  0.886181 
 
 
-
 
NC_007958  RPD_0328  response regulator receiver  32.46 
 
 
147 aa  73.9  0.0000000000007  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.0634669  normal 
 
 
-
 
NC_011757  Mchl_0516  response regulator receiver protein  38.53 
 
 
124 aa  73.2  0.000000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.131947  normal 
 
 
-
 
NC_007778  RPB_2945  response regulator receiver domain-containing protein  33.62 
 
 
124 aa  72.4  0.000000000002  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.161273  normal  0.393497 
 
 
-
 
NC_009507  Swit_5396  response regulator receiver protein  32.54 
 
 
132 aa  72.4  0.000000000002  Sphingomonas wittichii RW1  Bacteria  normal  0.476573  normal 
 
 
-
 
NC_011989  Avi_1195  Two component sensor kinase/response regulator hybrid protein  36.89 
 
 
130 aa  71.2  0.000000000004  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_010510  Mrad2831_5790  response regulator receiver protein  32.48 
 
 
122 aa  70.9  0.000000000005  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.0889979  normal  0.112489 
 
 
-
 
NC_010505  Mrad2831_2732  response regulator receiver protein  36.28 
 
 
151 aa  70.9  0.000000000006  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.169998 
 
 
-
 
NC_010172  Mext_0144  hypothetical protein  39.29 
 
 
118 aa  70.5  0.000000000007  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_4573  response regulator receiver  38.26 
 
 
134 aa  70.1  0.000000000009  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.546072 
 
 
-
 
NC_011757  Mchl_5033  response regulator receiver protein  38.26 
 
 
134 aa  70.1  0.000000000009  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.649741  normal  0.0493927 
 
 
-
 
NC_007492  Pfl01_2650  response regulator receiver domain-containing protein  43.21 
 
 
125 aa  68.9  0.00000000002  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.6169 
 
 
-
 
NC_007778  RPB_0497  response regulator receiver domain-containing protein  34.55 
 
 
125 aa  69.3  0.00000000002  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0614776  normal 
 
 
-
 
NC_010725  Mpop_0095  response regulator receiver protein  36.36 
 
 
123 aa  68.9  0.00000000002  Methylobacterium populi BJ001  Bacteria  normal  0.898425  normal 
 
 
-
 
NC_011757  Mchl_4539  response regulator receiver protein  36.36 
 
 
120 aa  69.3  0.00000000002  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.866024  normal 
 
 
-
 
NC_011984  Avi_9028  two component sensor kinase/response regulator hybrid  32.73 
 
 
123 aa  68.6  0.00000000002  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_010172  Mext_4170  response regulator receiver  36.36 
 
 
120 aa  69.3  0.00000000002  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_2989  response regulator receiver protein  33.33 
 
 
120 aa  68.6  0.00000000003  Pseudomonas putida GB-1  Bacteria  normal  normal  0.319214 
 
 
-
 
NC_010725  Mpop_3551  response regulator receiver protein  35.92 
 
 
143 aa  67.4  0.00000000006  Methylobacterium populi BJ001  Bacteria  normal  0.0862504  normal 
 
 
-
 
NC_010725  Mpop_5091  response regulator receiver protein  38.05 
 
 
134 aa  67.4  0.00000000007  Methylobacterium populi BJ001  Bacteria  normal  0.947919  normal 
 
 
-
 
NC_010172  Mext_4112  response regulator receiver  38.14 
 
 
128 aa  67  0.00000000008  Methylobacterium extorquens PA1  Bacteria  normal  0.576276  normal  0.834365 
 
 
-
 
NC_011757  Mchl_4480  response regulator receiver protein  38.14 
 
 
128 aa  67  0.00000000008  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.361856  normal 
 
 
-
 
NC_004578  PSPTO_2716  response regulator  40.24 
 
 
125 aa  66.2  0.0000000001  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.59583  n/a   
 
 
-
 
NC_010725  Mpop_4683  response regulator receiver protein  36.04 
 
 
120 aa  66.6  0.0000000001  Methylobacterium populi BJ001  Bacteria  normal  0.409248  normal 
 
 
-
 
NC_004578  PSPTO_1870  sensory box histidine kinase/response regulator  37 
 
 
691 aa  65.1  0.0000000003  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_4593  response regulator receiver protein  36.36 
 
 
129 aa  65.1  0.0000000003  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_007005  Psyr_2449  response regulator receiver  39.02 
 
 
142 aa  64.7  0.0000000004  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  hitchhiker  0.000856797 
 
 
-
 
NC_009511  Swit_4398  response regulator receiver protein  33.63 
 
 
127 aa  64.7  0.0000000004  Sphingomonas wittichii RW1  Bacteria  normal  0.481257  normal 
 
 
-
 
NC_010725  Mpop_2488  response regulator receiver protein  42.2 
 
 
173 aa  63.9  0.0000000006  Methylobacterium populi BJ001  Bacteria  normal  0.365206  normal  0.13004 
 
 
-
 
NC_011365  Gdia_2320  response regulator receiver protein  33.05 
 
 
127 aa  63.9  0.0000000007  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  normal  0.632565 
 
 
-
 
NC_011894  Mnod_0143  response regulator receiver protein  39.6 
 
 
130 aa  63.5  0.0000000008  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.363881  n/a   
 
 
-
 
NC_007005  Psyr_3532  PAS  37 
 
 
691 aa  63.5  0.0000000009  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.804686  normal  0.0772354 
 
 
-
 
NC_011894  Mnod_7165  response regulator receiver protein  34.51 
 
 
143 aa  63.5  0.0000000009  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.272897  n/a   
 
 
-
 
NC_011004  Rpal_4537  response regulator receiver protein  33.33 
 
 
125 aa  63.2  0.000000001  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_2780  response regulator receiver protein  39.47 
 
 
173 aa  63.2  0.000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_2557  response regulator receiver  40.35 
 
 
194 aa  63.2  0.000000001  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_3757  response regulator receiver protein  40.74 
 
 
125 aa  62  0.000000002  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_6328  response regulator receiver protein  33.63 
 
 
141 aa  62.4  0.000000002  Methylobacterium sp. 4-46  Bacteria  normal  hitchhiker  0.00633094 
 
 
-
 
NC_010172  Mext_1882  response regulator receiver  40 
 
 
108 aa  62.8  0.000000002  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_012850  Rleg_0771  response regulator receiver protein  29.91 
 
 
130 aa  62  0.000000002  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_4665  response regulator receiver protein  29.17 
 
 
127 aa  62  0.000000002  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.191751 
 
 
-
 
NC_010682  Rpic_0029  PAS/PAC sensor hybrid histidine kinase  33.06 
 
 
732 aa  62  0.000000002  Ralstonia pickettii 12J  Bacteria  normal  normal  0.598305 
 
 
-
 
NC_009512  Pput_2006  response regulator receiver protein  40.74 
 
 
125 aa  62  0.000000002  Pseudomonas putida F1  Bacteria  normal  normal  0.267349 
 
 
-
 
NC_012856  Rpic12D_0024  PAS/PAC sensor hybrid histidine kinase  33.88 
 
 
734 aa  62  0.000000003  Ralstonia pickettii 12D  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_5605  response regulator receiver protein  39.81 
 
 
198 aa  61.2  0.000000004  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.469743  normal 
 
 
-
 
NC_012853  Rleg_5645  response regulator receiver protein  32.17 
 
 
182 aa  61.2  0.000000004  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.633042  normal 
 
 
-
 
NC_007958  RPD_2510  response regulator receiver  32.04 
 
 
124 aa  61.2  0.000000005  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.294916 
 
 
-
 
NC_010725  Mpop_4814  response regulator receiver protein  28.33 
 
 
127 aa  60.8  0.000000006  Methylobacterium populi BJ001  Bacteria  normal  0.24379  normal  0.163877 
 
 
-
 
NC_011368  Rleg2_4740  response regulator receiver protein  33.33 
 
 
126 aa  60.8  0.000000006  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3529  response regulator receiver domain-containing protein  28.35 
 
 
137 aa  60.5  0.000000007  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.440569  normal  0.421617 
 
 
-
 
NC_010338  Caul_0906  response regulator receiver protein  34.19 
 
 
125 aa  60.5  0.000000007  Caulobacter sp. K31  Bacteria  normal  normal  0.101181 
 
 
-
 
NC_010501  PputW619_2110  response regulator receiver protein  39.51 
 
 
125 aa  60.5  0.000000008  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_2146  response regulator receiver protein  39.51 
 
 
125 aa  60.5  0.000000008  Pseudomonas putida GB-1  Bacteria  normal  0.41399  hitchhiker  0.000968824 
 
 
-
 
NC_011004  Rpal_3632  PAS/PAC sensor hybrid histidine kinase  42.17 
 
 
686 aa  59.7  0.00000001  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007778  RPB_0545  multi-sensor hybrid histidine kinase  30 
 
 
1053 aa  59.7  0.00000001  Rhodopseudomonas palustris HaA2  Bacteria  normal  normal  0.0920041 
 
 
-
 
NC_011988  Avi_5545  two component sensor kinase/response regulator hybrid  38.18 
 
 
1036 aa  59.7  0.00000001  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_4367  response regulator receiver protein  35.29 
 
 
130 aa  60.1  0.00000001  Methylobacterium populi BJ001  Bacteria  normal  normal  0.711428 
 
 
-
 
NC_010581  Bind_3015  integral membrane sensor hybrid histidine kinase  33.06 
 
 
762 aa  60.1  0.00000001  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_006349  BMAA0137  sensory box histidine kinase/response regulator  31.4 
 
 
611 aa  58.9  0.00000002  Burkholderia mallei ATCC 23344  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_3211  PAS/PAC sensor hybrid histidine kinase  30.7 
 
 
696 aa  58.9  0.00000002  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.7085  normal 
 
 
-
 
NC_010501  PputW619_2578  PAS/PAC sensor hybrid histidine kinase  37.89 
 
 
689 aa  59.3  0.00000002  Pseudomonas putida W619  Bacteria  normal  normal  0.800994 
 
 
-
 
NC_008391  Bamb_4524  PAS/PAC sensor hybrid histidine kinase  31.09 
 
 
589 aa  58.9  0.00000002  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_008784  BMASAVP1_1307  sensory box histidine kinase/response regulator  31.4 
 
 
611 aa  58.9  0.00000002  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_007435  BURPS1710b_A1041  sensory box histidine kinase/response regulator  31.4 
 
 
611 aa  58.5  0.00000003  Burkholderia pseudomallei 1710b  Bacteria  normal  n/a   
 
 
-
 
NC_009075  BURPS668_A2778  Signal transduction histidine kinase  31.4 
 
 
611 aa  58.5  0.00000003  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_009078  BURPS1106A_A2635  sensory box histidine kinase/response regulator  31.4 
 
 
611 aa  58.5  0.00000003  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_6212  response regulator receiver protein  38.53 
 
 
177 aa  58.5  0.00000003  Methylobacterium sp. 4-46  Bacteria  normal  0.0392664  normal  0.598992 
 
 
-
 
NC_010515  Bcenmc03_5170  PAS/PAC sensor hybrid histidine kinase  29.92 
 
 
588 aa  58.2  0.00000004  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.0474386 
 
 
-
 
NC_010511  M446_0675  response regulator receiver protein  37.84 
 
 
129 aa  58.2  0.00000004  Methylobacterium sp. 4-46  Bacteria  normal  0.410105  normal 
 
 
-
 
NC_010571  Oter_2217  histidine kinase  34.45 
 
 
396 aa  58.2  0.00000004  Opitutus terrae PB90-1  Bacteria  normal  normal  0.0256212 
 
 
-
 
NC_010717  PXO_01573  response regulator  32.67 
 
 
109 aa  57.8  0.00000004  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.877013  n/a   
 
 
-
 
NC_007958  RPD_0284  multi-sensor hybrid histidine kinase  31.4 
 
 
1105 aa  58.2  0.00000004  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.0846765 
 
 
-
 
NC_008061  Bcen_3257  PAS/PAC sensor hybrid histidine kinase  29.92 
 
 
589 aa  58.2  0.00000004  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_008543  Bcen2424_5111  PAS/PAC sensor hybrid histidine kinase  29.92 
 
 
589 aa  58.2  0.00000004  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
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