More than 300 homologs were found in PanDaTox collection
for query gene Mpe_A3585 on replicon NC_008825
Organism: Methylibium petroleiphilum PM1



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_008825  Mpe_A3585  two component LuxR family transcriptional regulator  100 
 
 		 306 aa  611  9.999999999999999e-175  Methylibium petroleiphilum PM1  Bacteria  normal  0.295986  normal  1 
 
 
-
 
NC_007948  Bpro_0562  two component LuxR family transcriptional regulator  71.33 
 
 		 297 aa  393  1e-108  Polaromonas sp. JS666  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012791  Vapar_3147  two component transcriptional regulator, LuxR family  72.39 
 
 		 302 aa  386  1e-106  Variovorax paradoxus S110  Bacteria  normal  0.235206  n/a   
 
 
-
 
NC_010002  Daci_0218  two component LuxR family transcriptional regulator  56.53 
 
 		 339 aa  331  1e-89  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009485  BBta_0652  two component LuxR family transcriptional regulator  48.81 
 
 		 305 aa  258  9e-68  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.0800453  normal  0.813173 
 
 
-
 
NC_011004  Rpal_1441  two component transcriptional regulator, LuxR family  49.66 
 
 		 308 aa  256  4e-67  Rhodopseudomonas palustris TIE-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_007958  RPD_3866  response regulator receiver  47.95 
 
 		 309 aa  255  6e-67  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.370865  normal  1 
 
 
-
 
NC_010511  M446_0591  two component LuxR family transcriptional regulator  48.99 
 
 		 301 aa  254  1.0000000000000001e-66  Methylobacterium sp. 4-46  Bacteria  normal  0.477799  hitchhiker  0.00469436 
 
 
-
 
NC_007778  RPB_1250  two component LuxR family transcriptional regulator  47.77 
 
 		 309 aa  253  4.0000000000000004e-66  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.886948  normal  1 
 
 
-
 
NC_009620  Smed_4179  response regulator receiver protein  46.71 
 
 		 309 aa  248  7e-65  Sinorhizobium medicae WSM419  Bacteria  normal  1  normal  0.15819 
 
 
-
 
NC_010524  Lcho_1083  two component LuxR family transcriptional regulator  48.51 
 
 		 316 aa  248  8e-65  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  1 
 
 
-
 
NC_007298  Daro_1445  two component LuxR family transcriptional regulator  49.03 
 
 		 308 aa  248  1e-64  Dechloromonas aromatica RCB  Bacteria  normal  0.446624  normal  1 
 
 
-
 
NC_008825  Mpe_A0671  two component LuxR family transcriptional regulator  49.5 
 
 		 333 aa  247  1e-64  Methylibium petroleiphilum PM1  Bacteria  normal  0.0205263  normal  1 
 
 
-
 
NC_011369  Rleg2_3066  two component transcriptional regulator, LuxR family  48.84 
 
 		 305 aa  248  1e-64  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010581  Bind_0974  two component LuxR family transcriptional regulator  47.18 
 
 		 309 aa  246  3e-64  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.883175  normal  0.426964 
 
 
-
 
NC_007952  Bxe_B1713  two component LuxR family transcriptional regulator  42.15 
 
 		 361 aa  244  9.999999999999999e-64  Burkholderia xenovorans LB400  Bacteria  normal  0.310925  normal  1 
 
 
-
 
NC_007912  Sde_2977  response regulator receiver domain-containing protein  46.21 
 
 		 303 aa  243  3e-63  Saccharophagus degradans 2-40  Bacteria  normal  1  normal  0.13601 
 
 
-
 
NC_011666  Msil_2002  two component transcriptional regulator, LuxR family  46.49 
 
 		 306 aa  242  6e-63  Methylocella silvestris BL2  Bacteria  n/a    normal  1 
 
 
-
 
NC_012850  Rleg_3321  two component transcriptional regulator, LuxR family  47.52 
 
 		 305 aa  241  7.999999999999999e-63  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  1  normal  0.536368 
 
 
-
 
NC_008740  Maqu_3869  response regulator receiver protein  46.98 
 
 		 301 aa  239  4e-62  Marinobacter aquaeolei VT8  Bacteria  normal  1  n/a   
 
 
-
 
NC_011989  Avi_3499  transcriptional regulator LuxR family  45.57 
 
 		 312 aa  238  6.999999999999999e-62  Agrobacterium vitis S4  Bacteria  normal  1  n/a   
 
 
-
 
NC_007947  Mfla_1761  two component LuxR family transcriptional regulator  46.92 
 
 		 311 aa  238  8e-62  Methylobacillus flagellatus KT  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008781  Pnap_0979  response regulator receiver protein  44.92 
 
 		 336 aa  236  3e-61  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007908  Rfer_3397  two component LuxR family transcriptional regulator  47 
 
 		 328 aa  236  4e-61  Rhodoferax ferrireducens T118  Bacteria  normal  1  n/a   
 
 
-
 
NC_007948  Bpro_1354  two component LuxR family transcriptional regulator  45.43 
 
 		 349 aa  235  5.0000000000000005e-61  Polaromonas sp. JS666  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013422  Hneap_1587  two component transcriptional regulator, LuxR family  46.28 
 
 		 292 aa  234  2.0000000000000002e-60  Halothiobacillus neapolitanus c2  Bacteria  normal  0.522901  n/a   
 
 
-
 
NC_010725  Mpop_3574  two component transcriptional regulator, LuxR family  48.64 
 
 		 301 aa  233  3e-60  Methylobacterium populi BJ001  Bacteria  normal  0.0249095  normal  1 
 
 
-
 
NC_009654  Mmwyl1_0962  response regulator receiver protein  44.74 
 
 		 304 aa  232  5e-60  Marinomonas sp. MWYL1  Bacteria  normal  0.512477  normal  1 
 
 
-
 
NC_011757  Mchl_3692  two component transcriptional regulator, LuxR family  47.99 
 
 		 300 aa  230  3e-59  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.170876  normal  1 
 
 
-
 
NC_010172  Mext_3383  response regulator receiver  47.99 
 
 		 300 aa  230  3e-59  Methylobacterium extorquens PA1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010505  Mrad2831_5514  two component LuxR family transcriptional regulator  47.51 
 
 		 305 aa  226  4e-58  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  1  normal  0.211273 
 
 
-
 
NC_008752  Aave_3524  two component LuxR family transcriptional regulator  46.15 
 
 		 353 aa  226  5.0000000000000005e-58  Acidovorax citrulli AAC00-1  Bacteria  normal  0.406085  normal  0.428998 
 
 
-
 
NC_008061  Bcen_3730  two component LuxR family transcriptional regulator  45.21 
 
 		 312 aa  224  1e-57  Burkholderia cenocepacia AU 1054  Bacteria  normal  1  n/a   
 
 
-
 
NC_008543  Bcen2424_4638  two component LuxR family transcriptional regulator  45.21 
 
 		 312 aa  224  1e-57  Burkholderia cenocepacia HI2424  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010515  Bcenmc03_5666  two component LuxR family transcriptional regulator  44.88 
 
 		 312 aa  223  3e-57  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  0.917296 
 
 
-
 
NC_008786  Veis_1731  response regulator receiver protein  46.65 
 
 		 361 aa  217  2e-55  Verminephrobacter eiseniae EF01-2  Bacteria  normal  1  normal  0.319975 
 
 
-
 
NC_012791  Vapar_4238  two component transcriptional regulator, LuxR family  40.98 
 
 		 356 aa  216  4e-55  Variovorax paradoxus S110  Bacteria  normal  1  n/a   
 
 
-
 
NC_007794  Saro_1665  two component LuxR family transcriptional regulator  43.94 
 
 		 307 aa  211  2e-53  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  1  n/a   
 
 
-
 
NC_011138  MADE_00878  two-component response regulator  40.67 
 
 		 298 aa  206  3e-52  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  1  n/a   
 
 
-
 
NC_008709  Ping_2984  two component transcriptional regulator, LuxR family protein  42.61 
 
 		 295 aa  206  5e-52  Psychromonas ingrahamii 37  Bacteria  normal  0.43543  normal  0.546259 
 
 
-
 
NC_010571  Oter_1720  two component LuxR family transcriptional regulator  40.65 
 
 		 301 aa  195  6e-49  Opitutus terrae PB90-1  Bacteria  normal  0.162572  normal  0.616267 
 
 
-
 
NC_004578  PSPTO_4080  DNA-binding response regulator, LuxR family  46.67 
 
 		 222 aa  156  3e-37  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.542388  n/a   
 
 
-
 
NC_013730  Slin_2507  two component, sigma54 specific, transcriptional regulator, Fis family  38.83 
 
 		 488 aa  146  4.0000000000000006e-34  Spirosoma linguale DSM 74  Bacteria  normal  1  normal  0.182398 
 
 
-
 
NC_011884  Cyan7425_0790  multi-sensor signal transduction histidine kinase  50.76 
 
 		 566 aa  145  1e-33  Cyanothece sp. PCC 7425  Bacteria  normal  0.391268  normal  1 
 
 
-
 
NC_011884  Cyan7425_3210  response regulator receiver modulated diguanylate cyclase  51.18 
 
 		 337 aa  144  3e-33  Cyanothece sp. PCC 7425  Bacteria  normal  0.32327  normal  0.712325 
 
 
-
 
NC_013440  Hoch_6548  response regulator receiver sensor signal transduction histidine kinase  51.91 
 
 		 397 aa  139  6e-32  Haliangium ochraceum DSM 14365  Bacteria  normal  1  normal  0.543575 
 
 
-
 
NC_010623  Bphy_4530  response regulator receiver sensor signal transduction histidine kinase  51.94 
 
 		 386 aa  139  6e-32  Burkholderia phymatum STM815  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010676  Bphyt_6236  multi-sensor signal transduction histidine kinase  53.39 
 
 		 553 aa  137  3.0000000000000003e-31  Burkholderia phytofirmans PsJN  Bacteria  normal  1  normal  0.914679 
 
 
-
 
NC_007413  Ava_2149  response regulator receiver Signal transduction histidine kinase  48.92 
 
 		 407 aa  136  4e-31  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  0.142048 
 
 
-
 
NC_010551  BamMC406_1236  response regulator receiver sensor signal transduction histidine kinase  50.39 
 
 		 386 aa  136  5e-31  Burkholderia ambifaria MC40-6  Bacteria  normal  0.493129  normal  1 
 
 
-
 
NC_010814  Glov_1118  response regulator receiver sensor signal transduction histidine kinase  47.76 
 
 		 452 aa  135  9.999999999999999e-31  Geobacter lovleyi SZ  Bacteria  hitchhiker  0.000972917  n/a   
 
 
-
 
NC_010571  Oter_0809  response regulator receiver sensor signal transduction histidine kinase  54.78 
 
 		 367 aa  133  3.9999999999999996e-30  Opitutus terrae PB90-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007413  Ava_2562  response regulator receiver Signal transduction histidine kinase  47.29 
 
 		 437 aa  130  2.0000000000000002e-29  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010625  Bphy_6559  multi-sensor signal transduction histidine kinase  54.78 
 
 		 541 aa  129  7.000000000000001e-29  Burkholderia phymatum STM815  Bacteria  normal  1  normal  0.59439 
 
 
-
 
NC_011146  Gbem_1018  response regulator receiver sensor signal transduction histidine kinase  46.88 
 
 		 441 aa  127  2.0000000000000002e-28  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.00729938  n/a   
 
 
-
 
NC_010627  Bphy_7700  multi-sensor signal transduction histidine kinase  54.78 
 
 		 541 aa  126  4.0000000000000003e-28  Burkholderia phymatum STM815  Bacteria  normal  0.163324  normal  0.507763 
 
 
-
 
NC_014248  Aazo_4465  response regulator receiver sensor signal transduction histidine kinase  43.8 
 
 		 437 aa  125  6e-28  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_012918  GM21_3242  response regulator receiver sensor signal transduction histidine kinase  46.32 
 
 		 441 aa  125  7e-28  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_007413  Ava_4136  response regulator receiver Signal transduction histidine kinase  44.44 
 
 		 440 aa  125  8.000000000000001e-28  Anabaena variabilis ATCC 29413  Bacteria  decreased coverage  0.00000660181  hitchhiker  0.00876613 
 
 
-
 
NC_013161  Cyan8802_1169  response regulator receiver modulated diguanylate cyclase  40.29 
 
 		 308 aa  125  1e-27  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011726  PCC8801_1139  response regulator receiver modulated diguanylate cyclase  40.29 
 
 		 308 aa  125  1e-27  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_008312  Tery_4155  response regulator receiver sensor signal transduction histidine kinase  45.38 
 
 		 440 aa  124  3e-27  Trichodesmium erythraeum IMS101  Bacteria  normal  0.50715  normal  1 
 
 
-
 
NC_009767  Rcas_3134  response regulator receiver protein  52.03 
 
 		 200 aa  123  4e-27  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009997  Sbal195_0871  response regulator receiver modulated metal dependent phosphohydrolase  46.27 
 
 		 338 aa  122  5e-27  Shewanella baltica OS195  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013440  Hoch_2175  response regulator receiver sensor signal transduction histidine kinase  50.41 
 
 		 395 aa  123  5e-27  Haliangium ochraceum DSM 14365  Bacteria  normal  0.924768  normal  0.400775 
 
 
-
 
NC_009665  Shew185_0836  response regulator receiver modulated metal dependent phosphohydrolase  46.27 
 
 		 338 aa  122  6e-27  Shewanella baltica OS185  Bacteria  normal  1  n/a   
 
 
-
 
NC_009052  Sbal_3504  response regulator receiver modulated metal dependent phosphohydrolase  46.27 
 
 		 338 aa  122  6e-27  Shewanella baltica OS155  Bacteria  normal  1  n/a   
 
 
-
 
NC_011663  Sbal223_0859  response regulator receiver modulated metal dependent phosphohydrolase  46.27 
 
 		 338 aa  122  6e-27  Shewanella baltica OS223  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014248  Aazo_4229  response regulator receiver sensor signal transduction histidine kinase  46.34 
 
 		 383 aa  121  9.999999999999999e-27  'Nostoc azollae' 0708  Bacteria  normal  0.599633  n/a   
 
 
-
 
NC_010814  Glov_3523  response regulator receiver modulated metal dependent phosphohydrolase  54.78 
 
 		 363 aa  122  9.999999999999999e-27  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_004347  SO_0860  response regulator  48.12 
 
 		 339 aa  120  1.9999999999999998e-26  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_009523  RoseRS_2347  response regulator receiver protein  48.06 
 
 		 202 aa  119  6e-26  Roseiflexus sp. RS-1  Bacteria  normal  0.56815  normal  1 
 
 
-
 
NC_007413  Ava_2150  response regulator receiver Signal transduction histidine kinase  46.72 
 
 		 443 aa  119  7.999999999999999e-26  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  0.394463 
 
 
-
 
NC_010571  Oter_3856  response regulator receiver sensor signal transduction histidine kinase  43.88 
 
 		 378 aa  118  9.999999999999999e-26  Opitutus terrae PB90-1  Bacteria  normal  1  normal  0.215089 
 
 
-
 
NC_009438  Sputcn32_3141  response regulator receiver modulated metal dependent phosphohydrolase  47.37 
 
 		 338 aa  118  9.999999999999999e-26  Shewanella putrefaciens CN-32  Bacteria  normal  1  n/a   
 
 
-
 
NC_008321  Shewmr4_0716  response regulator receiver modulated metal dependent phosphohydrolase  47.37 
 
 		 338 aa  118  9.999999999999999e-26  Shewanella sp. MR-4  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008322  Shewmr7_3306  response regulator receiver modulated metal dependent phosphohydrolase  47.37 
 
 		 338 aa  118  9.999999999999999e-26  Shewanella sp. MR-7  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013161  Cyan8802_1380  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  36.36 
 
 		 715 aa  118  9.999999999999999e-26  Cyanothece sp. PCC 8802  Bacteria  normal  0.923401  normal  1 
 
 
-
 
NC_008577  Shewana3_3418  response regulator receiver modulated metal dependent phosphohydrolase  47.37 
 
 		 338 aa  118  9.999999999999999e-26  Shewanella sp. ANA-3  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011726  PCC8801_1350  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  35.83 
 
 		 715 aa  116  3.9999999999999997e-25  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_009012  Cthe_1826  response regulator receiver sensor signal transduction histidine kinase  45.22 
 
 		 363 aa  116  3.9999999999999997e-25  Clostridium thermocellum ATCC 27405  Bacteria  normal  1  n/a   
 
 
-
 
NC_012560  Avin_25160  response regulator  48.48 
 
 		 356 aa  116  6e-25  Azotobacter vinelandii DJ  Bacteria  normal  1  n/a   
 
 
-
 
NC_011146  Gbem_1228  response regulator receiver modulated diguanylate cyclase  43.85 
 
 		 349 aa  115  7.999999999999999e-25  Geobacter bemidjiensis Bem  Bacteria  normal  1  n/a   
 
 
-
 
NC_009092  Shew_3199  response regulator receiver modulated metal dependent phosphohydrolase  46.21 
 
 		 339 aa  115  7.999999999999999e-25  Shewanella loihica PV-4  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011729  PCC7424_0178  response regulator receiver modulated diguanylate cyclase  40.31 
 
 		 322 aa  115  8.999999999999998e-25  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.895619 
 
 
-
 
NC_011726  PCC8801_2041  response regulator receiver modulated diguanylate cyclase  40.82 
 
 		 317 aa  115  1.0000000000000001e-24  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_2067  response regulator receiver modulated diguanylate cyclase  40.82 
 
 		 317 aa  115  1.0000000000000001e-24  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009901  Spea_0629  response regulator receiver modulated metal dependent phosphohydrolase  46.21 
 
 		 339 aa  115  1.0000000000000001e-24  Shewanella pealeana ATCC 700345  Bacteria  normal  1  n/a   
 
 
-
 
NC_008700  Sama_2951  response regulator receiver protein  47.73 
 
 		 340 aa  114  2.0000000000000002e-24  Shewanella amazonensis SB2B  Bacteria  normal  1  normal  0.129077 
 
 
-
 
NC_010681  Bphyt_2397  two component transcriptional regulator, AraC family  43.28 
 
 		 269 aa  114  3e-24  Burkholderia phytofirmans PsJN  Bacteria  normal  0.92999  normal  0.351016 
 
 
-
 
NC_008340  Mlg_2429  response regulator receiver modulated metal dependent phosphohydrolase  48.39 
 
 		 480 aa  113  3e-24  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  1  normal  0.129673 
 
 
-
 
NC_009654  Mmwyl1_1086  response regulator receiver modulated metal dependent phosphohydrolase  45.11 
 
 		 331 aa  113  3e-24  Marinomonas sp. MWYL1  Bacteria  normal  0.226857  hitchhiker  0.0000000112469 
 
 
-
 
NC_008687  Pden_3311  response regulator receiver protein  33.01 
 
 		 321 aa  112  7.000000000000001e-24  Paracoccus denitrificans PD1222  Bacteria  normal  1  normal  0.479786 
 
 
-
 
NC_014248  Aazo_1477  response regulator receiver modulated diguanylate cyclase  38.69 
 
 		 317 aa  112  9e-24  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_1577  response regulator receiver modulated diguanylate cyclase  46.96 
 
 		 314 aa  112  1.0000000000000001e-23  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007517  Gmet_2999  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  43.9 
 
 		 361 aa  110  2.0000000000000002e-23  Geobacter metallireducens GS-15  Bacteria  normal  1  normal  0.669597 
 
 
-
 
NC_011726  PCC8801_2743  response regulator receiver sensor signal transduction histidine kinase  40.77 
 
 		 395 aa  111  2.0000000000000002e-23  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_008345  Sfri_2505  response regulator receiver modulated metal dependent phosphohydrolase  45.04 
 
 		 331 aa  110  2.0000000000000002e-23  Shewanella frigidimarina NCIMB 400  Bacteria  normal  1  n/a   
 
 
-
 
NC_013161  Cyan8802_3359  response regulator receiver sensor signal transduction histidine kinase  40.77 
 
 		 395 aa  111  2.0000000000000002e-23  Cyanothece sp. PCC 8802  Bacteria  normal  0.361398  normal  1 
 
 
-
 
NC_007413  Ava_3976  response regulator receiver Signal transduction histidine kinase  51.72 
 
 		 431 aa  110  3e-23  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0119459  decreased coverage  0.00202838 
 
 
-
 
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