More than 300 homologs were found in PanDaTox collection
for query gene M446_4214 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010511  M446_4214  response regulator receiver protein  100 
 
 
130 aa  261  2e-69  Methylobacterium sp. 4-46  Bacteria  normal  0.843954  normal  0.213428 
 
 
-
 
NC_010172  Mext_3363  response regulator receiver  68.55 
 
 
126 aa  168  2e-41  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_6418  response regulator receiver protein  66.12 
 
 
126 aa  164  5e-40  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_1895  response regulator receiver  66.67 
 
 
126 aa  157  4e-38  Methylobacterium extorquens PA1  Bacteria  normal  0.208302  normal 
 
 
-
 
NC_010725  Mpop_1475  response regulator receiver protein  58.87 
 
 
124 aa  139  9e-33  Methylobacterium populi BJ001  Bacteria  normal  0.292646  normal  0.101486 
 
 
-
 
NC_010725  Mpop_4593  response regulator receiver protein  53.6 
 
 
129 aa  128  3e-29  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_0516  response regulator receiver protein  55.74 
 
 
124 aa  128  3e-29  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.131947  normal 
 
 
-
 
NC_010725  Mpop_0095  response regulator receiver protein  55.37 
 
 
123 aa  127  5.0000000000000004e-29  Methylobacterium populi BJ001  Bacteria  normal  0.898425  normal 
 
 
-
 
NC_011757  Mchl_4480  response regulator receiver protein  55.2 
 
 
128 aa  127  5.0000000000000004e-29  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.361856  normal 
 
 
-
 
NC_010172  Mext_4112  response regulator receiver  55.2 
 
 
128 aa  127  5.0000000000000004e-29  Methylobacterium extorquens PA1  Bacteria  normal  0.576276  normal  0.834365 
 
 
-
 
NC_007778  RPB_4041  response regulator receiver domain-containing protein  56.73 
 
 
124 aa  121  3e-27  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0979956  normal 
 
 
-
 
NC_011004  Rpal_1668  response regulator receiver protein  53.77 
 
 
131 aa  117  4.9999999999999996e-26  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_007958  RPD_3796  response regulator receiver  54.72 
 
 
124 aa  116  7.999999999999999e-26  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.787937 
 
 
-
 
NC_010172  Mext_0144  hypothetical protein  62.5 
 
 
118 aa  115  1.9999999999999998e-25  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011666  Msil_0850  response regulator receiver protein  53.33 
 
 
131 aa  112  2.0000000000000002e-24  Methylocella silvestris BL2  Bacteria  n/a    normal  0.886181 
 
 
-
 
NC_012850  Rleg_2931  response regulator receiver protein  47.83 
 
 
122 aa  112  2.0000000000000002e-24  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.139057  normal 
 
 
-
 
NC_011369  Rleg2_2670  response regulator receiver protein  47.83 
 
 
122 aa  111  3e-24  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.313891  normal 
 
 
-
 
NC_010505  Mrad2831_0691  response regulator receiver protein  50.93 
 
 
128 aa  109  1.0000000000000001e-23  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.852187  normal  0.378672 
 
 
-
 
NC_011666  Msil_3741  response regulator receiver protein  52.88 
 
 
127 aa  105  2e-22  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_010172  Mext_3150  response regulator receiver  53.27 
 
 
128 aa  105  2e-22  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_3346  response regulator receiver protein  53.27 
 
 
128 aa  105  2e-22  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_007925  RPC_1228  response regulator receiver domain-containing protein  53.47 
 
 
124 aa  105  2e-22  Rhodopseudomonas palustris BisB18  Bacteria  normal  hitchhiker  0.0000969205 
 
 
-
 
NC_011757  Mchl_3474  response regulator receiver protein  53.27 
 
 
128 aa  105  2e-22  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.212338  normal 
 
 
-
 
NC_010511  M446_2634  response regulator receiver protein  47.01 
 
 
135 aa  102  2e-21  Methylobacterium sp. 4-46  Bacteria  normal  0.873964  normal  0.0480327 
 
 
-
 
NC_011004  Rpal_4537  response regulator receiver protein  48.51 
 
 
125 aa  97.8  4e-20  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_009511  Swit_4398  response regulator receiver protein  43.64 
 
 
127 aa  96.3  1e-19  Sphingomonas wittichii RW1  Bacteria  normal  0.481257  normal 
 
 
-
 
NC_012850  Rleg_0771  response regulator receiver protein  45.05 
 
 
130 aa  95.5  2e-19  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_4665  response regulator receiver protein  43.48 
 
 
127 aa  95.9  2e-19  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.191751 
 
 
-
 
NC_011894  Mnod_4811  response regulator receiver protein  45.05 
 
 
140 aa  95.1  3e-19  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_007958  RPD_0328  response regulator receiver  41.38 
 
 
147 aa  93.6  8e-19  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.0634669  normal 
 
 
-
 
NC_011984  Avi_9028  two component sensor kinase/response regulator hybrid  43.69 
 
 
123 aa  92.8  2e-18  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011894  Mnod_3607  response regulator receiver protein  42.24 
 
 
135 aa  92  2e-18  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.621989  n/a   
 
 
-
 
NC_012853  Rleg_5645  response regulator receiver protein  40 
 
 
182 aa  92  2e-18  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.633042  normal 
 
 
-
 
NC_010725  Mpop_4814  response regulator receiver protein  42.02 
 
 
127 aa  91.7  3e-18  Methylobacterium populi BJ001  Bacteria  normal  0.24379  normal  0.163877 
 
 
-
 
NC_011989  Avi_1195  Two component sensor kinase/response regulator hybrid protein  46.53 
 
 
130 aa  92  3e-18  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_007778  RPB_2945  response regulator receiver domain-containing protein  40.54 
 
 
124 aa  91.3  4e-18  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.161273  normal  0.393497 
 
 
-
 
NC_010725  Mpop_0775  response regulator receiver protein  41.18 
 
 
132 aa  91.3  4e-18  Methylobacterium populi BJ001  Bacteria  normal  normal  0.0313977 
 
 
-
 
NC_010172  Mext_4296  response regulator receiver  41.44 
 
 
115 aa  90.5  7e-18  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_3963  response regulator receiver protein  41.96 
 
 
133 aa  90.1  9e-18  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.150847 
 
 
-
 
NC_010505  Mrad2831_2499  response regulator receiver protein  47.01 
 
 
136 aa  87.8  4e-17  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.353166  normal 
 
 
-
 
NC_011365  Gdia_2320  response regulator receiver protein  41.59 
 
 
127 aa  87.8  4e-17  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  normal  0.632565 
 
 
-
 
NC_010505  Mrad2831_2732  response regulator receiver protein  39.84 
 
 
151 aa  88.2  4e-17  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.169998 
 
 
-
 
NC_010172  Mext_4573  response regulator receiver  41.18 
 
 
134 aa  87.4  5e-17  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.546072 
 
 
-
 
NC_010725  Mpop_5091  response regulator receiver protein  41.18 
 
 
134 aa  87.8  5e-17  Methylobacterium populi BJ001  Bacteria  normal  0.947919  normal 
 
 
-
 
NC_011757  Mchl_5033  response regulator receiver protein  41.18 
 
 
134 aa  87.4  5e-17  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.649741  normal  0.0493927 
 
 
-
 
NC_011757  Mchl_0810  response regulator receiver protein  39.5 
 
 
132 aa  87  8e-17  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.316292 
 
 
-
 
NC_010172  Mext_0851  response regulator receiver  39.5 
 
 
132 aa  87  8e-17  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.234035 
 
 
-
 
NC_011666  Msil_2794  response regulator receiver protein  44.55 
 
 
125 aa  86.7  9e-17  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_010505  Mrad2831_0864  response regulator receiver protein  41.67 
 
 
129 aa  86.7  1e-16  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  hitchhiker  0.00632773 
 
 
-
 
NC_007778  RPB_0497  response regulator receiver domain-containing protein  42.34 
 
 
125 aa  85.5  2e-16  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.0614776  normal 
 
 
-
 
NC_007958  RPD_2510  response regulator receiver  39.64 
 
 
124 aa  85.5  2e-16  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.294916 
 
 
-
 
NC_010172  Mext_1882  response regulator receiver  43.69 
 
 
108 aa  84.3  5e-16  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_7165  response regulator receiver protein  40.16 
 
 
143 aa  82.8  0.000000000000001  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.272897  n/a   
 
 
-
 
NC_012858  Rleg_6937  response regulator receiver protein  47.78 
 
 
133 aa  82.8  0.000000000000001  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0671376  normal 
 
 
-
 
NC_010511  M446_6328  response regulator receiver protein  38.58 
 
 
141 aa  82.4  0.000000000000002  Methylobacterium sp. 4-46  Bacteria  normal  hitchhiker  0.00633094 
 
 
-
 
NC_009507  Swit_5396  response regulator receiver protein  40.57 
 
 
132 aa  81.6  0.000000000000004  Sphingomonas wittichii RW1  Bacteria  normal  0.476573  normal 
 
 
-
 
NC_011894  Mnod_7092  response regulator receiver protein  43.14 
 
 
196 aa  79  0.00000000000002  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.08524  n/a   
 
 
-
 
NC_010505  Mrad2831_5535  response regulator receiver protein  40.71 
 
 
130 aa  78.2  0.00000000000003  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.591914  decreased coverage  0.00892468 
 
 
-
 
NC_009485  BBta_7425  putative response regulator receiver (CheY-like protein)  41.35 
 
 
133 aa  78.6  0.00000000000003  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.0404716 
 
 
-
 
NC_007925  RPC_3132  PAS/PAC sensor hybrid histidine kinase  37.5 
 
 
743 aa  77.8  0.00000000000004  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.583735  normal 
 
 
-
 
NC_011368  Rleg2_5228  response regulator receiver protein  35.45 
 
 
135 aa  78.2  0.00000000000004  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.0214459  normal  0.509013 
 
 
-
 
NC_010172  Mext_1889  ATPase domain-containing protein  41.74 
 
 
280 aa  77.8  0.00000000000005  Methylobacterium extorquens PA1  Bacteria  normal  0.508337  normal 
 
 
-
 
NC_002947  PP_3969  response regulator  35.24 
 
 
120 aa  77  0.00000000000007  Pseudomonas putida KT2440  Bacteria  normal  normal  0.13044 
 
 
-
 
NC_010511  M446_6212  response regulator receiver protein  39.64 
 
 
177 aa  76.6  0.00000000000009  Methylobacterium sp. 4-46  Bacteria  normal  0.0392664  normal  0.598992 
 
 
-
 
NC_011757  Mchl_2780  response regulator receiver protein  37.74 
 
 
173 aa  76.3  0.0000000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0096  multi-sensor hybrid histidine kinase  40 
 
 
741 aa  75.9  0.0000000000002  Methylobacterium populi BJ001  Bacteria  normal  0.770159  normal 
 
 
-
 
NC_011368  Rleg2_4740  response regulator receiver protein  41.12 
 
 
126 aa  75.5  0.0000000000002  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0171  multi-sensor hybrid histidine kinase  40 
 
 
740 aa  75.9  0.0000000000002  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_012853  Rleg_5650  response regulator receiver protein  41.12 
 
 
128 aa  75.5  0.0000000000003  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.343299  normal  0.64647 
 
 
-
 
NC_010172  Mext_2557  response regulator receiver  36.79 
 
 
194 aa  75.5  0.0000000000003  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_2488  response regulator receiver protein  37.74 
 
 
173 aa  75.1  0.0000000000003  Methylobacterium populi BJ001  Bacteria  normal  0.365206  normal  0.13004 
 
 
-
 
NC_004578  PSPTO_2711  response regulator  39.83 
 
 
119 aa  74.3  0.0000000000004  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.0615637  n/a   
 
 
-
 
NC_012853  Rleg_5929  response regulator receiver protein  39.62 
 
 
128 aa  74.7  0.0000000000004  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_0143  response regulator receiver protein  38.05 
 
 
130 aa  74.7  0.0000000000004  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.363881  n/a   
 
 
-
 
NC_007005  Psyr_2444  response regulator receiver  38.52 
 
 
123 aa  73.9  0.0000000000006  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.986911  decreased coverage  0.00021442 
 
 
-
 
NC_010717  PXO_01426  histidine kinase  35.83 
 
 
507 aa  73.2  0.000000000001  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.643455  n/a   
 
 
-
 
NC_007643  Rru_A3039  PAS/PAC sensor hybrid histidine kinase  42 
 
 
1067 aa  72.8  0.000000000001  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.635771  n/a   
 
 
-
 
NC_011071  Smal_1735  response regulator receiver protein  34.78 
 
 
119 aa  73.2  0.000000000001  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.419682 
 
 
-
 
NC_009832  Spro_1028  multi-sensor hybrid histidine kinase  35.65 
 
 
870 aa  73.2  0.000000000001  Serratia proteamaculans 568  Bacteria  normal  normal  0.636365 
 
 
-
 
NC_003910  CPS_4260  sensor histidine kinase/response regulator  31.86 
 
 
669 aa  72.4  0.000000000002  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_010322  PputGB1_2989  response regulator receiver protein  37.14 
 
 
120 aa  72.4  0.000000000002  Pseudomonas putida GB-1  Bacteria  normal  normal  0.319214 
 
 
-
 
NC_010623  Bphy_5407  PAS/PAC sensor hybrid histidine kinase  34.48 
 
 
815 aa  72.8  0.000000000002  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_6442  multi-sensor hybrid histidine kinase  36.28 
 
 
688 aa  72  0.000000000003  Methylobacterium sp. 4-46  Bacteria  normal  0.381857  normal 
 
 
-
 
NC_010505  Mrad2831_5605  response regulator receiver protein  40.38 
 
 
198 aa  70.9  0.000000000005  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.469743  normal 
 
 
-
 
NC_010511  M446_0861  response regulator receiver protein  42.34 
 
 
135 aa  70.9  0.000000000006  Methylobacterium sp. 4-46  Bacteria  normal  0.0503153  normal 
 
 
-
 
NC_007643  Rru_A2820  multi-sensor hybrid histidine kinase / cell cycle control histidine kinase CckA  39.09 
 
 
829 aa  70.9  0.000000000006  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_0093  response regulator receiver protein  44.44 
 
 
143 aa  70.5  0.000000000007  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_3795  multi-sensor hybrid histidine kinase  42.59 
 
 
807 aa  70.5  0.000000000007  Methylobacterium populi BJ001  Bacteria  normal  normal  0.750808 
 
 
-
 
NC_011369  Rleg2_1201  integral membrane sensor hybrid histidine kinase  38.53 
 
 
548 aa  70.5  0.000000000007  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.642458  normal 
 
 
-
 
NC_009428  Rsph17025_2740  PAS/PAC sensor hybrid histidine kinase  38.21 
 
 
943 aa  70.5  0.000000000007  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_7844  sensor histidine kinase  39.81 
 
 
529 aa  70.5  0.000000000007  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.651552 
 
 
-
 
NC_007005  Psyr_1300  PAS  33.05 
 
 
695 aa  70.1  0.000000000009  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal  0.233563 
 
 
-
 
NC_011894  Mnod_0073  response regulator receiver protein  37.14 
 
 
128 aa  70.1  0.000000000009  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_010510  Mrad2831_5790  response regulator receiver protein  39.42 
 
 
122 aa  69.7  0.00000000001  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.0889979  normal  0.112489 
 
 
-
 
NC_007517  Gmet_2824  multi-sensor hybrid histidine kinase  37.8 
 
 
1018 aa  69.7  0.00000000001  Geobacter metallireducens GS-15  Bacteria  normal  normal  0.0209449 
 
 
-
 
NC_010322  PputGB1_2991  response regulator receiver protein  32.46 
 
 
138 aa  70.1  0.00000000001  Pseudomonas putida GB-1  Bacteria  normal  normal  0.430733 
 
 
-
 
NC_012850  Rleg_1290  histidine kinase  39.45 
 
 
573 aa  69.7  0.00000000001  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.163396  normal 
 
 
-
 
NC_010465  YPK_0124  multi-sensor hybrid histidine kinase  34.23 
 
 
851 aa  69.3  0.00000000001  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_008391  Bamb_4524  PAS/PAC sensor hybrid histidine kinase  39.29 
 
 
589 aa  69.7  0.00000000001  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_3551  response regulator receiver protein  38 
 
 
143 aa  69.7  0.00000000001  Methylobacterium populi BJ001  Bacteria  normal  0.0862504  normal 
 
 
-
 
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