More than 300 homologs were found in PanDaTox collection
for query gene Tpau_2015 on replicon NC_014158
Organism: Tsukamurella paurometabola DSM 20162



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014158  Tpau_2015  two component transcriptional regulator, winged helix family  100 
 
 
228 aa  456  1e-127  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_3086  two component transcriptional regulator, winged helix family  52.23 
 
 
233 aa  209  3e-53  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.151774  normal  0.916258 
 
 
-
 
NC_013595  Sros_0132  response regulator receiver protein  50.89 
 
 
231 aa  204  7e-52  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_008541  Arth_1441  two component transcriptional regulator  49.09 
 
 
247 aa  203  2e-51  Arthrobacter sp. FB24  Bacteria  normal  0.167327  n/a   
 
 
-
 
NC_013947  Snas_0721  two component transcriptional regulator, winged helix family  49.56 
 
 
233 aa  197  7.999999999999999e-50  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.811558  normal 
 
 
-
 
NC_007777  Francci3_0978  two component transcriptional regulator  50 
 
 
321 aa  196  3e-49  Frankia sp. CcI3  Bacteria  normal  0.323902  normal 
 
 
-
 
NC_009380  Strop_1197  response regulator receiver  50.87 
 
 
230 aa  195  4.0000000000000005e-49  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_009953  Sare_1090  two component transcriptional regulator  50 
 
 
230 aa  187  1e-46  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.0839689 
 
 
-
 
NC_008148  Rxyl_2983  two component transcriptional regulator  45.33 
 
 
228 aa  184  1.0000000000000001e-45  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  45.41 
 
 
232 aa  184  1.0000000000000001e-45  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  44.39 
 
 
226 aa  183  2.0000000000000003e-45  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_010320  Teth514_0766  two component transcriptional regulator  39.83 
 
 
231 aa  181  6e-45  Thermoanaerobacter sp. X514  Bacteria  normal  0.585906  n/a   
 
 
-
 
NC_007912  Sde_3703  two component transcriptional regulator  41.85 
 
 
232 aa  181  7e-45  Saccharophagus degradans 2-40  Bacteria  normal  0.230236  normal  0.0884672 
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  41.15 
 
 
229 aa  180  1e-44  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_013235  Namu_1193  two component transcriptional regulator, winged helix family  46.51 
 
 
240 aa  180  1e-44  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_3818  two component transcriptional regulator  46.64 
 
 
230 aa  181  1e-44  Roseiflexus sp. RS-1  Bacteria  normal  0.386967  normal  0.165932 
 
 
-
 
NC_013216  Dtox_2729  two component transcriptional regulator, winged helix family  40.61 
 
 
228 aa  179  2e-44  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.981161  normal  0.424997 
 
 
-
 
NC_008146  Mmcs_0661  two component transcriptional regulator  43.56 
 
 
228 aa  180  2e-44  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_0674  two component transcriptional regulator  43.56 
 
 
228 aa  180  2e-44  Mycobacterium sp. KMS  Bacteria  normal  normal  0.850641 
 
 
-
 
NC_009077  Mjls_0654  two component transcriptional regulator  43.56 
 
 
228 aa  180  2e-44  Mycobacterium sp. JLS  Bacteria  normal  normal  0.682961 
 
 
-
 
NC_010320  Teth514_1155  two component transcriptional regulator  39.57 
 
 
231 aa  180  2e-44  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000430064  n/a   
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  45.37 
 
 
237 aa  179  2.9999999999999997e-44  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_009338  Mflv_0082  two component transcriptional regulator  43.11 
 
 
228 aa  179  4e-44  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_013441  Gbro_0997  response regulator receiver  43.56 
 
 
228 aa  178  4.999999999999999e-44  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  45.33 
 
 
236 aa  178  5.999999999999999e-44  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_008726  Mvan_0831  two component transcriptional regulator  42.67 
 
 
228 aa  178  5.999999999999999e-44  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.310785  normal 
 
 
-
 
NC_007604  Synpcc7942_1012  two component transcriptional regulator  45.11 
 
 
257 aa  178  7e-44  Synechococcus elongatus PCC 7942  Bacteria  normal  0.658807  normal 
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  43.36 
 
 
229 aa  177  9e-44  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_011898  Ccel_1157  two component transcriptional regulator, winged helix family  40.69 
 
 
233 aa  177  1e-43  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_20650  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  46.7 
 
 
231 aa  177  1e-43  Brachybacterium faecium DSM 4810  Bacteria  normal  0.0260682  n/a   
 
 
-
 
NC_011899  Hore_04710  two component transcriptional regulator, winged helix family  40.95 
 
 
237 aa  177  1e-43  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_0997  two component transcriptional regulator  45.29 
 
 
230 aa  177  1e-43  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.679101  normal 
 
 
-
 
NC_007333  Tfu_2910  response regulator receiver  43.95 
 
 
230 aa  177  2e-43  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_6749  two component transcriptional regulator, winged helix family  43.05 
 
 
226 aa  177  2e-43  Actinosynnema mirum DSM 43827  Bacteria  normal  0.290774  n/a   
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  41.23 
 
 
232 aa  176  2e-43  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  45.29 
 
 
226 aa  176  2e-43  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_009091  P9301_12431  two-component response regulator, phosphate  42.92 
 
 
242 aa  176  2e-43  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  0.15803  n/a   
 
 
-
 
NC_008148  Rxyl_0378  two component transcriptional regulator  44.64 
 
 
234 aa  176  2e-43  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_1673  two component transcriptional regulator, winged helix family  41.05 
 
 
233 aa  176  3e-43  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_013165  Shel_11290  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  40.17 
 
 
234 aa  176  4e-43  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_011830  Dhaf_0287  two component transcriptional regulator, winged helix family  39.56 
 
 
229 aa  175  4e-43  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00220806  n/a   
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  44.84 
 
 
231 aa  176  4e-43  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_007335  PMN2A_1196  two component transcriptional regulator  45.41 
 
 
246 aa  176  4e-43  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A3169  regulatory protein VanR  38.6 
 
 
229 aa  175  4e-43  Bacillus cereus B4264  Bacteria  normal  0.16404  n/a   
 
 
-
 
NC_008527  LACR_0444  DNA-binding response regulator  43.17 
 
 
233 aa  176  4e-43  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  n/a   
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  44.2 
 
 
228 aa  176  4e-43  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_008819  NATL1_20711  two-component response regulator  45.41 
 
 
246 aa  176  4e-43  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  46.85 
 
 
236 aa  175  4e-43  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  42.73 
 
 
229 aa  175  6e-43  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_011830  Dhaf_2918  two component transcriptional regulator, winged helix family  38.86 
 
 
232 aa  174  8e-43  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  43.95 
 
 
229 aa  174  8e-43  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_013552  DhcVS_926  two-component system, OmpR family, response regulator  41.89 
 
 
227 aa  174  9e-43  Dehalococcoides sp. VS  Bacteria  hitchhiker  0.00200634  n/a   
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  46.02 
 
 
240 aa  174  9e-43  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_009674  Bcer98_0264  two component transcriptional regulator  37.61 
 
 
238 aa  174  9.999999999999999e-43  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.392693  n/a   
 
 
-
 
NC_009012  Cthe_3069  two component transcriptional regulator  38.77 
 
 
230 aa  174  9.999999999999999e-43  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.0000000467461  n/a   
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  45.37 
 
 
236 aa  174  9.999999999999999e-43  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_009565  TBFG_10499  two component system sensor transduction protein regX3  41.96 
 
 
227 aa  174  9.999999999999999e-43  Mycobacterium tuberculosis F11  Bacteria  decreased coverage  2.46064e-66  normal 
 
 
-
 
NC_007577  PMT9312_0717  two component transcriptional regulator  42.92 
 
 
242 aa  174  9.999999999999999e-43  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  n/a   
 
 
-
 
NC_008817  P9515_18081  two-component response regulator  44.16 
 
 
248 aa  174  9.999999999999999e-43  Prochlorococcus marinus str. MIT 9515  Bacteria  normal  n/a   
 
 
-
 
NC_014158  Tpau_0654  two component transcriptional regulator, winged helix family  41.59 
 
 
229 aa  174  9.999999999999999e-43  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.200991  n/a   
 
 
-
 
NC_013501  Rmar_0987  two component transcriptional regulator, winged helix family  44.74 
 
 
233 aa  173  1.9999999999999998e-42  Rhodothermus marinus DSM 4252  Bacteria  normal  0.195539  n/a   
 
 
-
 
NC_010001  Cphy_3872  two component transcriptional regulator  38.22 
 
 
229 aa  173  1.9999999999999998e-42  Clostridium phytofermentans ISDg  Bacteria  normal  0.0547348  n/a   
 
 
-
 
NC_011830  Dhaf_1285  two component transcriptional regulator, winged helix family  38.63 
 
 
234 aa  173  1.9999999999999998e-42  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.477652  n/a   
 
 
-
 
NC_007577  PMT9312_1712  two component transcriptional regulator  43.72 
 
 
248 aa  173  1.9999999999999998e-42  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  n/a   
 
 
-
 
NC_009091  P9301_18111  two-component response regulator  44.16 
 
 
248 aa  173  1.9999999999999998e-42  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  43.5 
 
 
229 aa  172  2.9999999999999996e-42  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_0188  two component transcriptional regulator  44.69 
 
 
245 aa  172  2.9999999999999996e-42  Roseiflexus sp. RS-1  Bacteria  hitchhiker  0.00347389  normal  0.0545477 
 
 
-
 
NC_009012  Cthe_1394  two component transcriptional regulator  40.17 
 
 
236 aa  173  2.9999999999999996e-42  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000024965  n/a   
 
 
-
 
NC_008816  A9601_18291  two-component response regulator  43.72 
 
 
248 aa  172  3.9999999999999995e-42  Prochlorococcus marinus str. AS9601  Bacteria  normal  0.276613  n/a   
 
 
-
 
NC_014248  Aazo_0581  winged helix family two component transcriptional regulator  43.67 
 
 
242 aa  172  3.9999999999999995e-42  'Nostoc azollae' 0708  Bacteria  normal  0.296955  n/a   
 
 
-
 
NC_011830  Dhaf_3739  two component transcriptional regulator, winged helix family  44.39 
 
 
230 aa  172  5e-42  Desulfitobacterium hafniense DCB-2  Bacteria  decreased coverage  0.0000000000466515  n/a   
 
 
-
 
NC_005957  BT9727_4801  response regulator protein  38.22 
 
 
234 aa  172  5.999999999999999e-42  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.0000584394  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4666  two component transcriptional regulator  39.29 
 
 
233 aa  171  6.999999999999999e-42  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_1878  two component transcriptional regulator  43.23 
 
 
242 aa  171  6.999999999999999e-42  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.559477 
 
 
-
 
NC_011884  Cyan7425_1115  two component transcriptional regulator, winged helix family  42.29 
 
 
243 aa  171  6.999999999999999e-42  Cyanothece sp. PCC 7425  Bacteria  normal  0.0950226  normal 
 
 
-
 
NC_013205  Aaci_1728  two component transcriptional regulator, winged helix family  41.67 
 
 
233 aa  171  7.999999999999999e-42  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_4207  two component transcriptional regulator, winged helix family  42.79 
 
 
247 aa  171  1e-41  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_013172  Bfae_09290  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  42.29 
 
 
229 aa  170  1e-41  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0439  two component transcriptional regulator  42.08 
 
 
225 aa  170  1e-41  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000223011  n/a   
 
 
-
 
NC_011898  Ccel_2106  two component transcriptional regulator, winged helix family  41.07 
 
 
238 aa  171  1e-41  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_4046  response regulator receiver  42.34 
 
 
225 aa  171  1e-41  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_4351  two component transcriptional regulator  42.86 
 
 
245 aa  170  2e-41  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.110039  normal 
 
 
-
 
NC_013739  Cwoe_5905  two component transcriptional regulator, winged helix family  43.86 
 
 
237 aa  169  2e-41  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  43.53 
 
 
233 aa  170  2e-41  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_009976  P9211_17451  two-component response regulator  42.67 
 
 
269 aa  170  2e-41  Prochlorococcus marinus str. MIT 9211  Bacteria  normal  normal 
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  41.33 
 
 
235 aa  169  3e-41  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  40.97 
 
 
235 aa  169  3e-41  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_008312  Tery_0954  two component transcriptional regulator  42.79 
 
 
243 aa  169  3e-41  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.0817018 
 
 
-
 
NC_009077  Mjls_0703  two component transcriptional regulator  47.77 
 
 
237 aa  169  3e-41  Mycobacterium sp. JLS  Bacteria  normal  normal  0.273227 
 
 
-
 
NC_011658  BCAH187_A5254  regulatory protein VanR  38.43 
 
 
234 aa  169  3e-41  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_4602  two component transcriptional regulator, winged helix family  42.6 
 
 
226 aa  169  4e-41  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  43.05 
 
 
226 aa  169  4e-41  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_011772  BCG9842_B0283  regulatory protein VanR  38.7 
 
 
233 aa  169  4e-41  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_008146  Mmcs_0709  two component transcriptional regulator  47.77 
 
 
237 aa  169  4e-41  Mycobacterium sp. MCS  Bacteria  normal  0.156486  n/a   
 
 
-
 
NC_008705  Mkms_0723  two component transcriptional regulator  47.77 
 
 
237 aa  169  4e-41  Mycobacterium sp. KMS  Bacteria  normal  normal  0.0244444 
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  41.33 
 
 
235 aa  168  5e-41  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_013947  Snas_0580  two component transcriptional regulator, winged helix family  42.15 
 
 
226 aa  169  5e-41  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_007604  Synpcc7942_2416  two component transcriptional regulator  43.61 
 
 
255 aa  168  5e-41  Synechococcus elongatus PCC 7942  Bacteria  normal  normal  0.0279623 
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  44.69 
 
 
236 aa  168  5e-41  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_013216  Dtox_1554  two component transcriptional regulator, winged helix family  38.39 
 
 
229 aa  169  5e-41  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  hitchhiker  0.00709514 
 
 
-
 
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