More than 300 homologs were found in PanDaTox collection
for query gene LACR_0444 on replicon NC_008527
Organism: Lactococcus lactis subsp. cremoris SK11



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_008527  LACR_0444  DNA-binding response regulator  100 
 
 
233 aa  473  1e-132  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  n/a   
 
 
-
 
NC_008532  STER_1116  DNA-binding response regulator  74.25 
 
 
235 aa  357  9.999999999999999e-98  Streptococcus thermophilus LMD-9  Bacteria  normal  0.310768  n/a   
 
 
-
 
NC_004116  SAG0719  DNA-binding response regulator  72.22 
 
 
236 aa  347  8e-95  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.0951718  n/a   
 
 
-
 
NC_008530  LGAS_0064  DNA-binding response regulator  69.83 
 
 
235 aa  339  2e-92  Lactobacillus gasseri ATCC 33323  Bacteria  normal  0.611294  normal 
 
 
-
 
NC_009513  Lreu_0019  two component transcriptional regulator  69.4 
 
 
235 aa  331  5e-90  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_3409  two component transcriptional regulator, winged helix family  67.39 
 
 
236 aa  330  8e-90  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  68.4 
 
 
235 aa  327  8e-89  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  68.4 
 
 
235 aa  327  8e-89  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  68.4 
 
 
235 aa  327  8e-89  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_005957  BT9727_5147  response regulator  68.4 
 
 
235 aa  327  8e-89  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_006274  BCZK5163  response regulator  68.4 
 
 
235 aa  327  8e-89  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  68.4 
 
 
235 aa  327  8e-89  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  68.4 
 
 
235 aa  327  8e-89  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  68.4 
 
 
235 aa  327  8e-89  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  68.4 
 
 
235 aa  327  8e-89  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  68.4 
 
 
235 aa  327  9e-89  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_013411  GYMC61_3538  two component transcriptional regulator, winged helix family  67.1 
 
 
237 aa  326  2.0000000000000001e-88  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  67.97 
 
 
235 aa  325  5e-88  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_008531  LEUM_1950  DNA-binding response regulator  66.52 
 
 
235 aa  322  3e-87  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.100456  n/a   
 
 
-
 
NC_009487  SaurJH9_0018  two component transcriptional regulator  61.57 
 
 
233 aa  310  7.999999999999999e-84  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.70243  n/a   
 
 
-
 
NC_009632  SaurJH1_0018  response regulator receiver  61.57 
 
 
233 aa  310  7.999999999999999e-84  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_008528  OEOE_0105  DNA-binding response regulator  65.37 
 
 
237 aa  309  2.9999999999999997e-83  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP2534  DNA-binding response regulator YycF  60.34 
 
 
233 aa  306  2.0000000000000002e-82  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  59.47 
 
 
232 aa  278  5e-74  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0080  two component transcriptional regulator, winged helix family  58.52 
 
 
230 aa  270  2e-71  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_2903  two component transcriptional regulator, winged helix family  55.26 
 
 
234 aa  266  2e-70  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal 
 
 
-
 
NC_013205  Aaci_2922  two component transcriptional regulator, winged helix family  57.27 
 
 
230 aa  266  2.9999999999999995e-70  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.221617  n/a   
 
 
-
 
NC_011898  Ccel_3394  two component transcriptional regulator, winged helix family  56.14 
 
 
230 aa  265  5.999999999999999e-70  Clostridium cellulolyticum H10  Bacteria  normal  0.103692  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  53.45 
 
 
234 aa  248  6e-65  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  54.08 
 
 
235 aa  247  1e-64  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  50.64 
 
 
234 aa  245  4.9999999999999997e-64  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  50.64 
 
 
234 aa  245  4.9999999999999997e-64  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_005945  BAS4484  DNA-binding response regulator PhoP  51.72 
 
 
239 aa  239  2e-62  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4319  alkaline phosphatase synthesis response regulator  51.72 
 
 
239 aa  239  2e-62  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  51.72 
 
 
239 aa  239  2e-62  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4704  DNA-binding response regulator PhoP  51.72 
 
 
239 aa  239  2e-62  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000000673192 
 
 
-
 
NC_007530  GBAA_4833  DNA-binding response regulator PhoP  51.72 
 
 
239 aa  239  2e-62  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0982965  n/a   
 
 
-
 
NC_011658  BCAH187_A4714  DNA-binding response regulator PhoP  51.72 
 
 
239 aa  239  2e-62  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_4720  DNA-binding response regulator PhoP  51.72 
 
 
239 aa  239  2.9999999999999997e-62  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  51.72 
 
 
239 aa  238  4e-62  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  51.72 
 
 
239 aa  238  4e-62  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  51.72 
 
 
239 aa  238  8e-62  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP1256  alkaline phosphatase synthesis transcriptional regulatory protein PhoP  50.85 
 
 
236 aa  237  1e-61  Staphylococcus epidermidis RP62A  Bacteria  normal  0.577358  n/a   
 
 
-
 
NC_009674  Bcer98_3274  two component transcriptional regulator  52.16 
 
 
238 aa  235  4e-61  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  51.5 
 
 
239 aa  235  4e-61  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  51.5 
 
 
239 aa  235  4e-61  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  51.54 
 
 
239 aa  234  6e-61  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  51.33 
 
 
229 aa  232  3e-60  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  49.78 
 
 
229 aa  230  2e-59  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  51.97 
 
 
232 aa  229  2e-59  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0439  two component transcriptional regulator  48.47 
 
 
225 aa  229  4e-59  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000223011  n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  49.56 
 
 
226 aa  224  8e-58  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  49.15 
 
 
233 aa  224  9e-58  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  50.66 
 
 
235 aa  224  1e-57  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_008261  CPF_0623  DNA-binding response regulator  52.36 
 
 
231 aa  223  2e-57  Clostridium perfringens ATCC 13124  Bacteria  hitchhiker  0.000212568  n/a   
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  48.67 
 
 
229 aa  222  4e-57  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  45.92 
 
 
236 aa  221  7e-57  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_009616  Tmel_1838  two component transcriptional regulator  48.07 
 
 
239 aa  221  7e-57  Thermosipho melanesiensis BI429  Bacteria  hitchhiker  0.00000194698  n/a   
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  49.11 
 
 
228 aa  221  7e-57  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  48.72 
 
 
231 aa  220  9.999999999999999e-57  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_0154  two component transcriptional regulator  49.78 
 
 
238 aa  221  9.999999999999999e-57  Clostridium phytofermentans ISDg  Bacteria  normal  0.644268  n/a   
 
 
-
 
NC_010424  Daud_1419  two component transcriptional regulator  50.87 
 
 
231 aa  220  9.999999999999999e-57  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0720218  n/a   
 
 
-
 
NC_009718  Fnod_1490  two component transcriptional regulator  48.93 
 
 
239 aa  220  9.999999999999999e-57  Fervidobacterium nodosum Rt17-B1  Bacteria  unclonable  0.000000000120928  n/a   
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  50 
 
 
228 aa  220  9.999999999999999e-57  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_008531  LEUM_0585  DNA-binding response regulator  50.43 
 
 
230 aa  220  1.9999999999999999e-56  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  hitchhiker  0.00125793  n/a   
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  50 
 
 
229 aa  220  1.9999999999999999e-56  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  49.55 
 
 
223 aa  219  3e-56  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_008148  Rxyl_2983  two component transcriptional regulator  51.11 
 
 
228 aa  219  3e-56  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_008262  CPR_0609  DNA-binding response regulator  50.64 
 
 
231 aa  219  3.9999999999999997e-56  Clostridium perfringens SM101  Bacteria  hitchhiker  0.0000282114  n/a   
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  50.44 
 
 
226 aa  218  5e-56  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_010816  BLD_1073  putative response regulator  46.35 
 
 
234 aa  218  7.999999999999999e-56  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_0580  two component transcriptional regulator, winged helix family  49.12 
 
 
226 aa  218  8.999999999999998e-56  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_0997  two component transcriptional regulator  45.06 
 
 
230 aa  217  1e-55  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.679101  normal 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  50 
 
 
229 aa  217  2e-55  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_007333  Tfu_2910  response regulator receiver  49.34 
 
 
230 aa  216  2e-55  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  46.32 
 
 
236 aa  216  2.9999999999999998e-55  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  48.03 
 
 
232 aa  215  4e-55  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_0997  response regulator receiver  47.44 
 
 
228 aa  215  4e-55  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_0984  two component transcriptional regulator, winged helix family  48.57 
 
 
246 aa  215  4e-55  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.0723779 
 
 
-
 
NC_011898  Ccel_2106  two component transcriptional regulator, winged helix family  47.86 
 
 
238 aa  215  4e-55  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_2286  two component transcriptional regulator, winged helix family  46.46 
 
 
231 aa  215  5e-55  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000000000188753  n/a   
 
 
-
 
NC_013093  Amir_6749  two component transcriptional regulator, winged helix family  48.23 
 
 
226 aa  214  8e-55  Actinosynnema mirum DSM 43827  Bacteria  normal  0.290774  n/a   
 
 
-
 
NC_010816  BLD_0042  response regulator  47.93 
 
 
240 aa  214  9e-55  Bifidobacterium longum DJO10A  Bacteria  normal  0.382747  n/a   
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  49.56 
 
 
231 aa  214  9.999999999999999e-55  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013174  Jden_2083  two component transcriptional regulator, winged helix family  45.76 
 
 
237 aa  213  1.9999999999999998e-54  Jonesia denitrificans DSM 20603  Bacteria  normal  0.873655  normal 
 
 
-
 
NC_011830  Dhaf_4050  two component transcriptional regulator, winged helix family  47.64 
 
 
227 aa  213  1.9999999999999998e-54  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00552008  n/a   
 
 
-
 
NC_009523  RoseRS_3818  two component transcriptional regulator  44.59 
 
 
230 aa  213  1.9999999999999998e-54  Roseiflexus sp. RS-1  Bacteria  normal  0.386967  normal  0.165932 
 
 
-
 
NC_009565  TBFG_10499  two component system sensor transduction protein regX3  46.52 
 
 
227 aa  213  2.9999999999999995e-54  Mycobacterium tuberculosis F11  Bacteria  decreased coverage  2.46064e-66  normal 
 
 
-
 
NC_011830  Dhaf_3739  two component transcriptional regulator, winged helix family  48.23 
 
 
230 aa  212  3.9999999999999995e-54  Desulfitobacterium hafniense DCB-2  Bacteria  decreased coverage  0.0000000000466515  n/a   
 
 
-
 
NC_013169  Ksed_03700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  46.9 
 
 
226 aa  212  3.9999999999999995e-54  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.132847 
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  48.67 
 
 
237 aa  212  4.9999999999999996e-54  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_1237  two component transcriptional regulator, winged helix family  48.09 
 
 
232 aa  211  5.999999999999999e-54  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_008726  Mvan_0831  two component transcriptional regulator  47.19 
 
 
228 aa  211  7e-54  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.310785  normal 
 
 
-
 
NC_009338  Mflv_0082  two component transcriptional regulator  46.52 
 
 
228 aa  211  7.999999999999999e-54  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_014158  Tpau_0654  two component transcriptional regulator, winged helix family  47.16 
 
 
229 aa  211  1e-53  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.200991  n/a   
 
 
-
 
NC_009921  Franean1_6145  two component transcriptional regulator  49.12 
 
 
228 aa  210  1e-53  Frankia sp. EAN1pec  Bacteria  normal  normal  0.788201 
 
 
-
 
NC_010320  Teth514_1997  two component transcriptional regulator  49.13 
 
 
234 aa  210  2e-53  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.000000742772  n/a   
 
 
-
 
NC_009674  Bcer98_3233  two component transcriptional regulator  46.9 
 
 
230 aa  209  2e-53  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  47.77 
 
 
228 aa  210  2e-53  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_008146  Mmcs_0661  two component transcriptional regulator  46.75 
 
 
228 aa  209  3e-53  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
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