More than 300 homologs were found in PanDaTox collection
for query gene Cthe_2333 on replicon NC_009012
Organism: Clostridium thermocellum ATCC 27405



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009012  Cthe_2333  two component transcriptional regulator  100 
 
 
232 aa  470  1e-132  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_3394  two component transcriptional regulator, winged helix family  78.79 
 
 
230 aa  369  1e-101  Clostridium cellulolyticum H10  Bacteria  normal  0.103692  n/a   
 
 
-
 
NC_012034  Athe_0080  two component transcriptional regulator, winged helix family  66.08 
 
 
230 aa  303  2.0000000000000002e-81  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  61.84 
 
 
235 aa  292  2e-78  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  61.84 
 
 
235 aa  292  2e-78  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_005957  BT9727_5147  response regulator  61.84 
 
 
235 aa  292  2e-78  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_006274  BCZK5163  response regulator  61.84 
 
 
235 aa  292  2e-78  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  61.84 
 
 
235 aa  292  2e-78  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  61.84 
 
 
235 aa  292  2e-78  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  61.84 
 
 
235 aa  292  2e-78  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  61.84 
 
 
235 aa  292  3e-78  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  61.84 
 
 
235 aa  292  3e-78  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  61.84 
 
 
235 aa  291  4e-78  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  61.84 
 
 
235 aa  291  5e-78  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_013411  GYMC61_3538  two component transcriptional regulator, winged helix family  61.3 
 
 
237 aa  283  2.0000000000000002e-75  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009513  Lreu_0019  two component transcriptional regulator  59.83 
 
 
235 aa  282  3.0000000000000004e-75  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_3409  two component transcriptional regulator, winged helix family  60.26 
 
 
236 aa  279  2e-74  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_0444  DNA-binding response regulator  59.47 
 
 
233 aa  278  5e-74  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP2534  DNA-binding response regulator YycF  58.01 
 
 
233 aa  276  2e-73  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_0018  response regulator receiver  58.01 
 
 
233 aa  276  2e-73  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0018  two component transcriptional regulator  58.01 
 
 
233 aa  276  2e-73  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.70243  n/a   
 
 
-
 
NC_008531  LEUM_1950  DNA-binding response regulator  56.77 
 
 
235 aa  273  2.0000000000000002e-72  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.100456  n/a   
 
 
-
 
NC_008530  LGAS_0064  DNA-binding response regulator  57.94 
 
 
235 aa  270  2e-71  Lactobacillus gasseri ATCC 33323  Bacteria  normal  0.611294  normal 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  58.22 
 
 
229 aa  268  5e-71  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_008528  OEOE_0105  DNA-binding response regulator  55.79 
 
 
237 aa  265  2.9999999999999995e-70  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_004116  SAG0719  DNA-binding response regulator  56.09 
 
 
236 aa  261  4.999999999999999e-69  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.0951718  n/a   
 
 
-
 
NC_013205  Aaci_2922  two component transcriptional regulator, winged helix family  54.63 
 
 
230 aa  261  8e-69  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.221617  n/a   
 
 
-
 
NC_008532  STER_1116  DNA-binding response regulator  55.02 
 
 
235 aa  259  2e-68  Streptococcus thermophilus LMD-9  Bacteria  normal  0.310768  n/a   
 
 
-
 
NC_010718  Nther_2903  two component transcriptional regulator, winged helix family  52.36 
 
 
234 aa  259  2e-68  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  54.82 
 
 
239 aa  257  1e-67  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  54.82 
 
 
239 aa  257  1e-67  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_010424  Daud_1419  two component transcriptional regulator  54.94 
 
 
231 aa  255  4e-67  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0720218  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  53.88 
 
 
235 aa  247  1e-64  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  52.61 
 
 
233 aa  244  9.999999999999999e-64  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  54.55 
 
 
239 aa  240  2e-62  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_009616  Tmel_1838  two component transcriptional regulator  51.32 
 
 
239 aa  239  2.9999999999999997e-62  Thermosipho melanesiensis BI429  Bacteria  hitchhiker  0.00000194698  n/a   
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  52.19 
 
 
229 aa  239  2.9999999999999997e-62  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  53.71 
 
 
231 aa  238  4e-62  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  51.29 
 
 
232 aa  238  6.999999999999999e-62  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  53.51 
 
 
234 aa  238  9e-62  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  54.35 
 
 
235 aa  237  1e-61  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  50.66 
 
 
236 aa  237  1e-61  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_009012  Cthe_1394  two component transcriptional regulator  50 
 
 
236 aa  235  4e-61  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000024965  n/a   
 
 
-
 
NC_012034  Athe_1487  two component transcriptional regulator, winged helix family  50.86 
 
 
232 aa  233  1.0000000000000001e-60  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.487145  n/a   
 
 
-
 
NC_011898  Ccel_2106  two component transcriptional regulator, winged helix family  51.54 
 
 
238 aa  233  3e-60  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_009718  Fnod_1490  two component transcriptional regulator  48.9 
 
 
239 aa  231  1e-59  Fervidobacterium nodosum Rt17-B1  Bacteria  unclonable  0.000000000120928  n/a   
 
 
-
 
NC_008148  Rxyl_0378  two component transcriptional regulator  47.44 
 
 
234 aa  230  1e-59  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_008261  CPF_0623  DNA-binding response regulator  55.65 
 
 
231 aa  230  1e-59  Clostridium perfringens ATCC 13124  Bacteria  hitchhiker  0.000212568  n/a   
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  51.95 
 
 
226 aa  230  2e-59  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_009767  Rcas_0353  two component transcriptional regulator  48.91 
 
 
230 aa  229  3e-59  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.683455 
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  50.43 
 
 
239 aa  228  6e-59  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_4050  two component transcriptional regulator, winged helix family  54.63 
 
 
227 aa  228  7e-59  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00552008  n/a   
 
 
-
 
NC_013124  Afer_0200  two component transcriptional regulator, winged helix family  45.61 
 
 
242 aa  227  1e-58  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  0.0955644  n/a   
 
 
-
 
NC_009674  Bcer98_3274  two component transcriptional regulator  50.66 
 
 
238 aa  227  1e-58  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1658  two component transcriptional regulator, winged helix family  50 
 
 
230 aa  227  1e-58  Clostridium cellulolyticum H10  Bacteria  normal  0.515101  n/a   
 
 
-
 
NC_003909  BCE_4720  DNA-binding response regulator PhoP  49.57 
 
 
239 aa  226  3e-58  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_1673  two component transcriptional regulator, winged helix family  49.12 
 
 
233 aa  226  3e-58  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_2496  response regulator receiver  49.12 
 
 
225 aa  226  3e-58  Thermobifida fusca YX  Bacteria  normal  0.491467  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  49.13 
 
 
239 aa  225  5.0000000000000005e-58  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  49.13 
 
 
239 aa  225  5.0000000000000005e-58  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4704  DNA-binding response regulator PhoP  49.13 
 
 
239 aa  225  6e-58  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000000673192 
 
 
-
 
NC_005945  BAS4484  DNA-binding response regulator PhoP  49.13 
 
 
239 aa  225  6e-58  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4319  alkaline phosphatase synthesis response regulator  49.13 
 
 
239 aa  225  6e-58  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  49.13 
 
 
239 aa  225  6e-58  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4833  DNA-binding response regulator PhoP  49.13 
 
 
239 aa  225  6e-58  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0982965  n/a   
 
 
-
 
NC_011658  BCAH187_A4714  DNA-binding response regulator PhoP  49.13 
 
 
239 aa  225  6e-58  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  49.78 
 
 
256 aa  224  8e-58  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  48.46 
 
 
232 aa  224  8e-58  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  47.79 
 
 
236 aa  224  9e-58  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_010320  Teth514_0439  two component transcriptional regulator  48.44 
 
 
225 aa  224  9e-58  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000223011  n/a   
 
 
-
 
NC_013595  Sros_0132  response regulator receiver protein  50 
 
 
231 aa  224  9e-58  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  46.22 
 
 
229 aa  224  1e-57  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_010424  Daud_1897  two component transcriptional regulator  52.23 
 
 
227 aa  224  1e-57  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.151466  n/a   
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  46.49 
 
 
228 aa  223  2e-57  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  46.9 
 
 
226 aa  223  2e-57  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  49.34 
 
 
234 aa  223  3e-57  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  48 
 
 
226 aa  222  3e-57  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  47.11 
 
 
229 aa  223  3e-57  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_008262  CPR_0609  DNA-binding response regulator  54.35 
 
 
231 aa  223  3e-57  Clostridium perfringens SM101  Bacteria  hitchhiker  0.0000282114  n/a   
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  49.34 
 
 
234 aa  223  3e-57  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_008148  Rxyl_2983  two component transcriptional regulator  49.78 
 
 
228 aa  222  4e-57  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  49.78 
 
 
223 aa  222  4e-57  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_013169  Ksed_08590  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  47.77 
 
 
239 aa  222  4e-57  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.857083 
 
 
-
 
NC_014158  Tpau_0654  two component transcriptional regulator, winged helix family  45.74 
 
 
229 aa  222  4e-57  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.200991  n/a   
 
 
-
 
NC_013739  Cwoe_5905  two component transcriptional regulator, winged helix family  48.91 
 
 
237 aa  222  4.9999999999999996e-57  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_010320  Teth514_1997  two component transcriptional regulator  50 
 
 
234 aa  221  6e-57  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.000000742772  n/a   
 
 
-
 
NC_013510  Tcur_4043  two component transcriptional regulator, winged helix family  47.79 
 
 
225 aa  220  9.999999999999999e-57  Thermomonospora curvata DSM 43183  Bacteria  normal  0.728877  n/a   
 
 
-
 
NC_013093  Amir_6310  two component transcriptional regulator, winged helix family  46.9 
 
 
261 aa  220  1.9999999999999999e-56  Actinosynnema mirum DSM 43827  Bacteria  normal  0.534044  n/a   
 
 
-
 
NC_013441  Gbro_0997  response regulator receiver  46.64 
 
 
228 aa  219  1.9999999999999999e-56  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_3815  two component transcriptional regulator, winged helix family  47.62 
 
 
225 aa  219  3e-56  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0278114  normal  0.0118387 
 
 
-
 
NC_010001  Cphy_1986  two component transcriptional regulator  48.68 
 
 
240 aa  218  3.9999999999999997e-56  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_0235  two component transcriptional regulator  48.89 
 
 
230 aa  218  6e-56  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_20650  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  46.09 
 
 
231 aa  218  8.999999999999998e-56  Brachybacterium faecium DSM 4810  Bacteria  normal  0.0260682  n/a   
 
 
-
 
NC_002936  DET0135  DNA-binding response regulator  47.56 
 
 
230 aa  217  1e-55  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_1827  two component transcriptional regulator, winged helix family  46.9 
 
 
227 aa  217  1e-55  Jonesia denitrificans DSM 20603  Bacteria  normal  normal 
 
 
-
 
NC_013216  Dtox_1554  two component transcriptional regulator, winged helix family  46.49 
 
 
229 aa  217  1e-55  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  hitchhiker  0.00709514 
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  46.67 
 
 
226 aa  217  1e-55  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  46.02 
 
 
229 aa  217  1e-55  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_008541  Arth_2712  two component transcriptional regulator  47.79 
 
 
224 aa  217  1e-55  Arthrobacter sp. FB24  Bacteria  hitchhiker  0.00552555  n/a   
 
 
-
 
NC_011831  Cagg_2709  two component transcriptional regulator, winged helix family  49.57 
 
 
236 aa  216  2e-55  Chloroflexus aggregans DSM 9485  Bacteria  decreased coverage  0.0011921  normal 
 
 
-
 
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