More than 300 homologs were found in PanDaTox collection
for query gene Bfae_20650 on replicon NC_013172
Organism: Brachybacterium faecium DSM 4810



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013172  Bfae_20650  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  100 
 
 
231 aa  460  1e-129  Brachybacterium faecium DSM 4810  Bacteria  normal  0.0260682  n/a   
 
 
-
 
NC_007333  Tfu_2496  response regulator receiver  73.76 
 
 
225 aa  333  1e-90  Thermobifida fusca YX  Bacteria  normal  0.491467  n/a   
 
 
-
 
NC_013510  Tcur_4043  two component transcriptional regulator, winged helix family  72.65 
 
 
225 aa  330  1e-89  Thermomonospora curvata DSM 43183  Bacteria  normal  0.728877  n/a   
 
 
-
 
NC_013174  Jden_1827  two component transcriptional regulator, winged helix family  72.27 
 
 
227 aa  326  2.0000000000000001e-88  Jonesia denitrificans DSM 20603  Bacteria  normal  normal 
 
 
-
 
NC_013521  Sked_09340  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  68.92 
 
 
223 aa  321  7e-87  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.217912  normal  0.763127 
 
 
-
 
NC_011886  Achl_2443  two component transcriptional regulator, winged helix family  69.82 
 
 
224 aa  319  1.9999999999999998e-86  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00121019 
 
 
-
 
NC_008541  Arth_2712  two component transcriptional regulator  69.37 
 
 
224 aa  317  7e-86  Arthrobacter sp. FB24  Bacteria  hitchhiker  0.00552555  n/a   
 
 
-
 
NC_013093  Amir_6310  two component transcriptional regulator, winged helix family  69.16 
 
 
261 aa  316  2e-85  Actinosynnema mirum DSM 43827  Bacteria  normal  0.534044  n/a   
 
 
-
 
NC_014165  Tbis_0770  winged helix family two component transcriptional regulator  73.54 
 
 
225 aa  315  3e-85  Thermobispora bispora DSM 43833  Bacteria  normal  normal  0.10066 
 
 
-
 
NC_012669  Bcav_1240  two component transcriptional regulator, winged helix family  68.78 
 
 
227 aa  314  8e-85  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.729355  normal 
 
 
-
 
NC_013530  Xcel_2514  two component transcriptional regulator, winged helix family  68.92 
 
 
226 aa  311  3.9999999999999997e-84  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.24701  n/a   
 
 
-
 
NC_009664  Krad_3815  two component transcriptional regulator, winged helix family  70.14 
 
 
225 aa  311  4.999999999999999e-84  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0278114  normal  0.0118387 
 
 
-
 
NC_012803  Mlut_14770  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  69.23 
 
 
226 aa  308  5e-83  Micrococcus luteus NCTC 2665  Bacteria  normal  0.383411  n/a   
 
 
-
 
NC_013595  Sros_1412  response regulator receiver protein  71.75 
 
 
225 aa  306  1.0000000000000001e-82  Streptosporangium roseum DSM 43021  Bacteria  normal  0.285013  normal  0.0125199 
 
 
-
 
NC_014210  Ndas_3745  two component transcriptional regulator, winged helix family  70.85 
 
 
225 aa  305  4.0000000000000004e-82  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.5489  normal 
 
 
-
 
NC_014151  Cfla_2332  two component transcriptional regulator, winged helix family  71.43 
 
 
227 aa  302  2.0000000000000002e-81  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0100882  decreased coverage  0.00000063533 
 
 
-
 
NC_008699  Noca_1433  response regulator receiver  71.75 
 
 
248 aa  303  2.0000000000000002e-81  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_013169  Ksed_08590  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  66.82 
 
 
239 aa  302  3.0000000000000004e-81  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.857083 
 
 
-
 
NC_013131  Caci_7594  two component transcriptional regulator, winged helix family  70.4 
 
 
228 aa  300  2e-80  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal  0.0426147 
 
 
-
 
NC_008578  Acel_1765  two component transcriptional regulator  69.51 
 
 
225 aa  298  4e-80  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_013757  Gobs_4285  two component transcriptional regulator, winged helix family  66.06 
 
 
238 aa  296  1e-79  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.83647  n/a   
 
 
-
 
NC_013159  Svir_30940  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  69.23 
 
 
225 aa  296  1e-79  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_009953  Sare_0904  two component transcriptional regulator  65.78 
 
 
229 aa  293  2e-78  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.0335314 
 
 
-
 
NC_009380  Strop_0967  response regulator receiver  65.78 
 
 
229 aa  293  2e-78  Salinispora tropica CNB-440  Bacteria  normal  0.359698  normal  0.873584 
 
 
-
 
NC_008146  Mmcs_1347  two component transcriptional regulator  69.68 
 
 
228 aa  292  3e-78  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_1365  two component transcriptional regulator  69.68 
 
 
228 aa  292  3e-78  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_009077  Mjls_1381  two component transcriptional regulator  69.68 
 
 
228 aa  292  3e-78  Mycobacterium sp. JLS  Bacteria  normal  normal  0.497022 
 
 
-
 
NC_009565  TBFG_13275  two component system sensor transduction transcriptional regulatory protein mtrA  68.3 
 
 
228 aa  291  5e-78  Mycobacterium tuberculosis F11  Bacteria  normal  normal  0.656178 
 
 
-
 
NC_008726  Mvan_1752  two component transcriptional regulator  68.75 
 
 
228 aa  291  7e-78  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal  0.581522 
 
 
-
 
NC_009338  Mflv_4712  two component transcriptional regulator  69.23 
 
 
228 aa  290  9e-78  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.541483  normal  0.0134498 
 
 
-
 
NC_013235  Namu_4249  two component transcriptional regulator, winged helix family  67.26 
 
 
225 aa  290  2e-77  Nakamurella multipartita DSM 44233  Bacteria  normal  0.316157  normal 
 
 
-
 
NC_013441  Gbro_3637  response regulator receiver  69.09 
 
 
225 aa  284  5.999999999999999e-76  Gordonia bronchialis DSM 43247  Bacteria  normal  0.135674  n/a   
 
 
-
 
NC_014158  Tpau_1076  two component transcriptional regulator, winged helix family  63.48 
 
 
228 aa  271  5.000000000000001e-72  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_1849  two component transcriptional regulator, winged helix family  63.88 
 
 
229 aa  270  2e-71  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_010816  BLD_0042  response regulator  51.93 
 
 
240 aa  241  6e-63  Bifidobacterium longum DJO10A  Bacteria  normal  0.382747  n/a   
 
 
-
 
NC_008578  Acel_1832  two component transcriptional regulator  54.75 
 
 
245 aa  222  3e-57  Acidothermus cellulolyticus 11B  Bacteria  normal  0.366424  normal  0.561636 
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  46.09 
 
 
232 aa  218  8.999999999999998e-56  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_3394  two component transcriptional regulator, winged helix family  47.98 
 
 
230 aa  214  5.9999999999999996e-55  Clostridium cellulolyticum H10  Bacteria  normal  0.103692  n/a   
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  48.44 
 
 
228 aa  214  8e-55  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  49.79 
 
 
233 aa  214  9.999999999999999e-55  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_007513  Syncc9902_0308  two component transcriptional regulator  48.72 
 
 
248 aa  212  2.9999999999999995e-54  Synechococcus sp. CC9902  Bacteria  normal  0.030574  n/a   
 
 
-
 
NC_007516  Syncc9605_2384  two component transcriptional regulator  48.72 
 
 
259 aa  212  2.9999999999999995e-54  Synechococcus sp. CC9605  Bacteria  normal  normal 
 
 
-
 
NC_011884  Cyan7425_1115  two component transcriptional regulator, winged helix family  48.26 
 
 
243 aa  212  3.9999999999999995e-54  Cyanothece sp. PCC 7425  Bacteria  normal  0.0950226  normal 
 
 
-
 
NC_014248  Aazo_0581  winged helix family two component transcriptional regulator  48.23 
 
 
242 aa  211  5.999999999999999e-54  'Nostoc azollae' 0708  Bacteria  normal  0.296955  n/a   
 
 
-
 
NC_011729  PCC7424_4207  two component transcriptional regulator, winged helix family  47.83 
 
 
247 aa  211  5.999999999999999e-54  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  48.43 
 
 
256 aa  211  7.999999999999999e-54  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_1878  two component transcriptional regulator  48.23 
 
 
242 aa  211  7.999999999999999e-54  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.559477 
 
 
-
 
NC_011830  Dhaf_1673  two component transcriptional regulator, winged helix family  46.75 
 
 
233 aa  211  7.999999999999999e-54  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_0235  two component transcriptional regulator  47.09 
 
 
230 aa  209  2e-53  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  47.84 
 
 
235 aa  209  2e-53  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  47.81 
 
 
239 aa  209  3e-53  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_013205  Aaci_2570  two component transcriptional regulator, winged helix family  50.44 
 
 
239 aa  209  3e-53  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_011726  PCC8801_2302  two component transcriptional regulator, winged helix family  47.83 
 
 
243 aa  209  3e-53  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  47.81 
 
 
239 aa  209  3e-53  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_013161  Cyan8802_2353  two component transcriptional regulator, winged helix family  47.83 
 
 
243 aa  209  3e-53  Cyanothece sp. PCC 8802  Bacteria  normal  0.0794558  normal 
 
 
-
 
NC_008820  P9303_26531  two-component response regulator  47.44 
 
 
248 aa  209  3e-53  Prochlorococcus marinus str. MIT 9303  Bacteria  n/a    normal 
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  47.32 
 
 
235 aa  207  8e-53  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_010320  Teth514_1155  two component transcriptional regulator  45.18 
 
 
231 aa  207  9e-53  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000430064  n/a   
 
 
-
 
NC_009767  Rcas_0353  two component transcriptional regulator  50 
 
 
230 aa  207  1e-52  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.683455 
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  47.32 
 
 
235 aa  207  1e-52  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_013441  Gbro_0997  response regulator receiver  48.66 
 
 
228 aa  207  1e-52  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  47.73 
 
 
223 aa  207  1e-52  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  47.32 
 
 
235 aa  206  2e-52  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  47.32 
 
 
235 aa  206  2e-52  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_005957  BT9727_5147  response regulator  47.32 
 
 
235 aa  206  2e-52  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_006274  BCZK5163  response regulator  47.32 
 
 
235 aa  206  2e-52  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_007335  PMN2A_1500  two component transcriptional regulator  47.01 
 
 
248 aa  206  2e-52  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0766  two component transcriptional regulator  44.74 
 
 
231 aa  207  2e-52  Thermoanaerobacter sp. X514  Bacteria  normal  0.585906  n/a   
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  47.32 
 
 
235 aa  206  2e-52  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  47.32 
 
 
235 aa  206  2e-52  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  47.32 
 
 
235 aa  206  2e-52  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_008312  Tery_0954  two component transcriptional regulator  47.35 
 
 
243 aa  207  2e-52  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.0817018 
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  47.81 
 
 
239 aa  206  2e-52  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  47.32 
 
 
235 aa  206  2e-52  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_008819  NATL1_02061  two-component response regulator  47.01 
 
 
248 aa  206  2e-52  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal  0.540525 
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  46.26 
 
 
234 aa  206  2e-52  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  47.32 
 
 
235 aa  206  2e-52  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_002936  DET0135  DNA-binding response regulator  47.32 
 
 
230 aa  206  3e-52  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_1696  two component transcriptional regulator, winged helix family  46.58 
 
 
224 aa  206  3e-52  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  48.2 
 
 
226 aa  206  3e-52  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  48.67 
 
 
232 aa  206  3e-52  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  47.16 
 
 
239 aa  205  4e-52  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_2922  two component transcriptional regulator, winged helix family  49.55 
 
 
230 aa  205  4e-52  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.221617  n/a   
 
 
-
 
NC_007604  Synpcc7942_1453  two component transcriptional regulator  48.67 
 
 
244 aa  205  4e-52  Synechococcus elongatus PCC 7942  Bacteria  normal  0.952418  normal  0.0249242 
 
 
-
 
NC_013131  Caci_0793  two component transcriptional regulator, winged helix family  48.39 
 
 
225 aa  205  5e-52  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  48.65 
 
 
229 aa  205  6e-52  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  49.55 
 
 
229 aa  204  7e-52  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  46.72 
 
 
239 aa  204  8e-52  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  46.72 
 
 
239 aa  204  8e-52  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_012793  GWCH70_3409  two component transcriptional regulator, winged helix family  49.33 
 
 
236 aa  204  8e-52  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  48.21 
 
 
235 aa  204  1e-51  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_003909  BCE_4720  DNA-binding response regulator PhoP  47.6 
 
 
239 aa  204  1e-51  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS4484  DNA-binding response regulator PhoP  47.6 
 
 
239 aa  204  1e-51  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4319  alkaline phosphatase synthesis response regulator  47.6 
 
 
239 aa  204  1e-51  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  47.6 
 
 
239 aa  204  1e-51  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4833  DNA-binding response regulator PhoP  47.6 
 
 
239 aa  204  1e-51  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0982965  n/a   
 
 
-
 
NC_011773  BCAH820_4704  DNA-binding response regulator PhoP  47.6 
 
 
239 aa  204  1e-51  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000000673192 
 
 
-
 
NC_011658  BCAH187_A4714  DNA-binding response regulator PhoP  47.6 
 
 
239 aa  204  1e-51  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  45.78 
 
 
234 aa  203  1e-51  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  45.78 
 
 
234 aa  203  1e-51  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
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