More than 300 homologs were found in PanDaTox collection
for query gene Dret_2255 on replicon NC_013223
Organism: Desulfohalobium retbaense DSM 5692



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013223  Dret_2255  homocysteine S-methyltransferase  100 
 
 
350 aa  725    Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_007963  Csal_0065  homocysteine S-methyltransferase  57.83 
 
 
349 aa  390  1e-107  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2133  homocysteine S-methyltransferase  35.45 
 
 
319 aa  207  3e-52  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_0238  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.79 
 
 
609 aa  110  3e-23  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_009718  Fnod_0772  homocysteine S-methyltransferase  24.46 
 
 
780 aa  102  1e-20  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  0.0538889  n/a   
 
 
-
 
NC_011725  BCB4264_A4367  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.38 
 
 
610 aa  99  1e-19  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_0262  homocysteine S-methyltransferase  30.16 
 
 
813 aa  99  1e-19  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.00180962 
 
 
-
 
NC_013411  GYMC61_1524  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.42 
 
 
615 aa  98.2  2e-19  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011772  BCG9842_B0867  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.38 
 
 
610 aa  97.8  2e-19  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU2921  5-methyltetrahydrofolate-homocysteine methyltransferase, truncation  29.87 
 
 
804 aa  97.1  4e-19  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_0645  methionine synthase (B12-dependent)  25.78 
 
 
804 aa  94.7  2e-18  Clostridium thermocellum ATCC 27405  Bacteria  normal  0.474097  n/a   
 
 
-
 
NC_005945  BAS4157  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.77 
 
 
610 aa  94.7  2e-18  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_3996  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.77 
 
 
610 aa  94.7  2e-18  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4006  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.77 
 
 
610 aa  94.7  2e-18  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4479  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.77 
 
 
610 aa  94.7  2e-18  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A4386  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.77 
 
 
610 aa  94.7  2e-18  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4275  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.77 
 
 
610 aa  94.7  2e-18  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_007498  Pcar_2722  methionine synthase I (cobalamin-dependent) methyltransferase subunit  28.66 
 
 
801 aa  93.6  4e-18  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0325  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.35 
 
 
605 aa  93.6  4e-18  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_4333  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.46 
 
 
610 aa  92.4  9e-18  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0277  homocysteine S-methyltransferase  29.73 
 
 
811 aa  92.8  9e-18  Geobacter bemidjiensis Bem  Bacteria  normal  0.357222  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4109  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.3 
 
 
610 aa  92.4  9e-18  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_3632  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.37 
 
 
617 aa  92  1e-17  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_0708  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  29.12 
 
 
616 aa  91.3  2e-17  Geobacillus sp. WCH70  Bacteria  normal  0.0266464  n/a   
 
 
-
 
NC_010831  Cphamn1_2093  B12-dependent methionine synthase  28.48 
 
 
1227 aa  91.3  2e-17  Chlorobium phaeobacteroides BS1  Bacteria  normal  normal  0.883808 
 
 
-
 
NC_008609  Ppro_0283  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.5 
 
 
615 aa  91.7  2e-17  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_29240  B12-dependent methionine synthase  27.72 
 
 
1278 aa  90.5  4e-17  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_007954  Sden_1115  B12-dependent methionine synthase  28.57 
 
 
1241 aa  90.1  5e-17  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_19590  homocysteine S-methyltransferase  21.73 
 
 
819 aa  89  1e-16  Halothermothrix orenii H 168  Bacteria  normal  0.399567  n/a   
 
 
-
 
NC_009674  Bcer98_2984  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.69 
 
 
614 aa  88.6  1e-16  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_2941  homocysteine S-methyltransferase  26.58 
 
 
801 aa  87.8  3e-16  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.651468  normal 
 
 
-
 
NC_007512  Plut_0315  B12-dependent methionine synthase  27.42 
 
 
1225 aa  87.8  3e-16  Chlorobium luteolum DSM 273  Bacteria  normal  hitchhiker  0.000170465 
 
 
-
 
NC_008009  Acid345_3426  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.55 
 
 
617 aa  87.4  3e-16  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.41819  normal 
 
 
-
 
NC_009972  Haur_2544  methionine synthase  28.19 
 
 
1180 aa  87  5e-16  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.00356448  n/a   
 
 
-
 
NC_010320  Teth514_1211  homocysteine S-methyltransferase  25.84 
 
 
807 aa  86.7  6e-16  Thermoanaerobacter sp. X514  Bacteria  normal  0.0179968  n/a   
 
 
-
 
NC_011661  Dtur_0073  homocysteine S-methyltransferase  27.65 
 
 
290 aa  86.3  7e-16  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_2207  homocysteine S-methyltransferase  27.91 
 
 
800 aa  85.1  0.000000000000002  Desulfotomaculum reducens MI-1  Bacteria  normal  0.0270016  n/a   
 
 
-
 
NC_007484  Noc_1206  B12-dependent methionine synthase  26.89 
 
 
1232 aa  84.7  0.000000000000002  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_0489  homocysteine S-methyltransferase  27.04 
 
 
804 aa  85.1  0.000000000000002  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_007614  Nmul_A0045  B12-dependent methionine synthase  28.89 
 
 
1267 aa  84.7  0.000000000000002  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_1792  homocysteine S-methyltransferase  22.88 
 
 
774 aa  85.1  0.000000000000002  Petrotoga mobilis SJ95  Bacteria  normal  0.709712  n/a   
 
 
-
 
NC_010718  Nther_0682  homocysteine S-methyltransferase  25.26 
 
 
793 aa  84.7  0.000000000000002  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_2159  B12-dependent methionine synthase  26.84 
 
 
1236 aa  85.1  0.000000000000002  Pseudomonas mendocina ymp  Bacteria  normal  normal  0.088857 
 
 
-
 
NC_012034  Athe_0324  homocysteine S-methyltransferase  25.36 
 
 
413 aa  84.3  0.000000000000003  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0405  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  22.36 
 
 
613 aa  84.3  0.000000000000003  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0504  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.33 
 
 
605 aa  84.3  0.000000000000003  Geobacter metallireducens GS-15  Bacteria  normal  0.0120544  normal 
 
 
-
 
NC_009632  SaurJH1_0415  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  22.36 
 
 
613 aa  84.3  0.000000000000003  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_008700  Sama_0758  B12-dependent methionine synthase  26.32 
 
 
1246 aa  84.3  0.000000000000003  Shewanella amazonensis SB2B  Bacteria  normal  0.659122  normal 
 
 
-
 
NC_002976  SERP0035  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.64 
 
 
612 aa  83.6  0.000000000000004  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_010322  PputGB1_1982  B12-dependent methionine synthase  26.52 
 
 
1235 aa  84  0.000000000000004  Pseudomonas putida GB-1  Bacteria  normal  0.0368395  normal  0.238169 
 
 
-
 
NC_002947  PP_2375  B12-dependent methionine synthase  26.52 
 
 
1235 aa  83.6  0.000000000000005  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_3320  B12-dependent methionine synthase  26.52 
 
 
1235 aa  83.6  0.000000000000005  Pseudomonas putida F1  Bacteria  normal  normal  0.487541 
 
 
-
 
NC_009438  Sputcn32_2965  B12-dependent methionine synthase  27.04 
 
 
1244 aa  83.2  0.000000000000006  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_010501  PputW619_1888  B12-dependent methionine synthase  26.2 
 
 
1235 aa  83.2  0.000000000000006  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010001  Cphy_3258  homocysteine S-methyltransferase  25.8 
 
 
841 aa  83.2  0.000000000000006  Clostridium phytofermentans ISDg  Bacteria  normal  0.728955  n/a   
 
 
-
 
NC_007517  Gmet_0549  methionine synthase (B12-dependent)  26.95 
 
 
804 aa  82.8  0.000000000000009  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_004347  SO_1030  B12-dependent methionine synthase  26.13 
 
 
1244 aa  82  0.00000000000001  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_007005  Psyr_2464  B12-dependent methionine synthase  27.16 
 
 
1239 aa  82.4  0.00000000000001  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.782684  normal  0.0191622 
 
 
-
 
NC_013889  TK90_0182  methionine synthase  26.43 
 
 
1263 aa  82.4  0.00000000000001  Thioalkalivibrio sp. K90mix  Bacteria  normal  normal 
 
 
-
 
NC_013525  Tter_1187  homocysteine S-methyltransferase  22.63 
 
 
629 aa  82.4  0.00000000000001  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_011663  Sbal223_0995  B12-dependent methionine synthase  27.04 
 
 
1244 aa  82.4  0.00000000000001  Shewanella baltica OS223  Bacteria  normal  0.0391552  normal 
 
 
-
 
NC_009665  Shew185_0973  B12-dependent methionine synthase  27.04 
 
 
1244 aa  81.6  0.00000000000002  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_007794  Saro_3207  methionine synthase (B12-dependent)  27.16 
 
 
358 aa  81.6  0.00000000000002  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_1007  B12-dependent methionine synthase  27.04 
 
 
1244 aa  81.3  0.00000000000002  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_011901  Tgr7_0650  B12-dependent methionine synthase  28.85 
 
 
1250 aa  81.3  0.00000000000003  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_0872  B12-dependent methionine synthase  25.96 
 
 
1238 aa  80.9  0.00000000000003  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_008322  Shewmr7_3184  B12-dependent methionine synthase  25.33 
 
 
1244 aa  80.1  0.00000000000005  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008740  Maqu_1526  B12-dependent methionine synthase  26.11 
 
 
1232 aa  80.1  0.00000000000005  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_004578  PSPTO_2732  5-methyltetrahydrofolate--homocysteine methyltransferase  26.84 
 
 
1239 aa  80.1  0.00000000000006  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.0346659  n/a   
 
 
-
 
NC_009441  Fjoh_1508  homocysteine S-methyltransferase  26 
 
 
334 aa  80.1  0.00000000000006  Flavobacterium johnsoniae UW101  Bacteria  normal  n/a   
 
 
-
 
NC_008321  Shewmr4_0838  B12-dependent methionine synthase  26.23 
 
 
1244 aa  79.7  0.00000000000007  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_010803  Clim_2062  B12-dependent methionine synthase  25 
 
 
1228 aa  79.3  0.00000000000009  Chlorobium limicola DSM 245  Bacteria  normal  0.458303  n/a   
 
 
-
 
NC_010483  TRQ2_0680  homocysteine S-methyltransferase  24.7 
 
 
768 aa  79  0.0000000000001  Thermotoga sp. RQ2  Bacteria  normal  0.412837  n/a   
 
 
-
 
NC_007492  Pfl01_3107  B12-dependent methionine synthase  26.98 
 
 
1236 aa  79  0.0000000000001  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_1413  homocysteine S-methyltransferase  27.33 
 
 
806 aa  79  0.0000000000001  Pelobacter propionicus DSM 2379  Bacteria  normal  0.0607109  n/a   
 
 
-
 
NC_009831  Ssed_3739  B12-dependent methionine synthase  26.52 
 
 
1252 aa  78.2  0.0000000000002  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_4250  methionine synthase  25.97 
 
 
1261 aa  77.8  0.0000000000002  Spirosoma linguale DSM 74  Bacteria  normal  0.49174  normal 
 
 
-
 
NC_008025  Dgeo_1336  B12-dependent methionine synthase  27.48 
 
 
1226 aa  78.6  0.0000000000002  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.262937  normal 
 
 
-
 
NC_009052  Sbal_3368  B12-dependent methionine synthase  26.45 
 
 
1233 aa  78.6  0.0000000000002  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_4366  B12-dependent methionine synthase  26.94 
 
 
1247 aa  77.8  0.0000000000003  Methylobacterium sp. 4-46  Bacteria  normal  0.778137  normal 
 
 
-
 
NC_010506  Swoo_4088  B12-dependent methionine synthase  26.52 
 
 
1251 aa  77.8  0.0000000000003  Shewanella woodyi ATCC 51908  Bacteria  normal  normal  0.611508 
 
 
-
 
NC_009636  Smed_1771  methionine synthase I  28.01 
 
 
337 aa  77.4  0.0000000000003  Sinorhizobium medicae WSM419  Bacteria  normal  0.379105  normal  0.0676063 
 
 
-
 
NC_009720  Xaut_2832  B12-dependent methionine synthase  27.69 
 
 
1271 aa  77  0.0000000000004  Xanthobacter autotrophicus Py2  Bacteria  normal  normal  0.192266 
 
 
-
 
NC_009901  Spea_3384  B12-dependent methionine synthase  26.28 
 
 
1210 aa  77  0.0000000000004  Shewanella pealeana ATCC 700345  Bacteria  normal  0.73359  n/a   
 
 
-
 
NC_008577  Shewana3_3282  B12-dependent methionine synthase  26.14 
 
 
1244 aa  76.6  0.0000000000005  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_010622  Bphy_0191  homocysteine S-methyltransferase  27.06 
 
 
356 aa  76.6  0.0000000000006  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_008639  Cpha266_2102  B12-dependent methionine synthase  26.18 
 
 
1249 aa  76.6  0.0000000000006  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  0.876734  n/a   
 
 
-
 
NC_002939  GSU2974  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.68 
 
 
605 aa  76.3  0.0000000000007  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_008254  Meso_0328  B12-dependent methionine synthase  25.41 
 
 
1264 aa  76.3  0.0000000000007  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_004116  SAG2048  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  23.21 
 
 
614 aa  76.3  0.0000000000008  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_0656  homocysteine S-methyltransferase  25.62 
 
 
768 aa  75.9  0.0000000000009  Thermotoga petrophila RKU-1  Bacteria  normal  0.79655  n/a   
 
 
-
 
NC_007513  Syncc9902_1123  5-methyltetrahydrofolate--homocysteine methyltransferase  25.6 
 
 
1208 aa  75.5  0.000000000001  Synechococcus sp. CC9902  Bacteria  decreased coverage  0.00712875  n/a   
 
 
-
 
NC_013173  Dbac_1858  homocysteine S-methyltransferase  26.85 
 
 
803 aa  75.5  0.000000000001  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_007963  Csal_1889  B12-dependent methionine synthase  26.56 
 
 
1245 aa  75.5  0.000000000001  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_40670  B12-dependent methionine synthase  25.41 
 
 
1234 aa  75.9  0.000000000001  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.0754274  normal 
 
 
-
 
NC_009092  Shew_0710  B12-dependent methionine synthase  24.92 
 
 
1240 aa  74.7  0.000000000002  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_013159  Svir_27020  methionine synthase (B12-dependent)  26.74 
 
 
1184 aa  75.1  0.000000000002  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.12372  normal  0.910685 
 
 
-
 
NC_009656  PSPA7_3449  B12-dependent methionine synthase  25.74 
 
 
1234 aa  74.7  0.000000000002  Pseudomonas aeruginosa PA7  Bacteria  normal  0.625644  n/a   
 
 
-
 
NC_008390  Bamb_2965  methionine synthase  26.73 
 
 
355 aa  74.7  0.000000000002  Burkholderia ambifaria AMMD  Bacteria  normal  n/a   
 
 
-
 
NC_009616  Tmel_0729  homocysteine S-methyltransferase  23.26 
 
 
781 aa  75.1  0.000000000002  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
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