More than 300 homologs were found in PanDaTox collection
for query gene M446_1996 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009485  BBta_0711  response regulator receiver sensor signal transduction histidine kinase  63.59 
 
 
581 aa  710    Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_2117  histidine kinase  72.82 
 
 
631 aa  816    Methylobacterium extorquens PA1  Bacteria  normal  normal  0.0208634 
 
 
-
 
NC_007406  Nwi_3058  phage head-tail adaptor, putative  62 
 
 
580 aa  672    Nitrobacter winogradskyi Nb-255  Bacteria  decreased coverage  0.00943131  normal  0.0427518 
 
 
-
 
NC_010505  Mrad2831_3287  response regulator receiver sensor signal transduction histidine kinase  74.19 
 
 
584 aa  824    Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.847642  normal 
 
 
-
 
NC_011757  Mchl_2394  response regulator receiver sensor signal transduction histidine kinase  72.82 
 
 
593 aa  817    Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_1253  response regulator receiver sensor signal transduction histidine kinase  90.22 
 
 
584 aa  1028    Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_1996  response regulator receiver sensor signal transduction histidine kinase  100 
 
 
584 aa  1167    Methylobacterium sp. 4-46  Bacteria  normal  0.0327436  normal  0.170409 
 
 
-
 
NC_007778  RPB_4666  response regulator receiver sensor signal transduction histidine kinase  62.46 
 
 
578 aa  689    Rhodopseudomonas palustris HaA2  Bacteria  normal  normal 
 
 
-
 
NC_007925  RPC_0095  response regulator receiver sensor signal transduction histidine kinase  62.89 
 
 
582 aa  704    Rhodopseudomonas palustris BisB18  Bacteria  normal  normal 
 
 
-
 
NC_007958  RPD_4375  response regulator receiver sensor signal transduction histidine kinase  63.21 
 
 
550 aa  661    Rhodopseudomonas palustris BisB5  Bacteria  normal  normal 
 
 
-
 
NC_007964  Nham_3684  response regulator receiver sensor signal transduction histidine kinase  62.52 
 
 
580 aa  701    Nitrobacter hamburgensis X14  Bacteria  normal  0.896547  n/a   
 
 
-
 
NC_010725  Mpop_2070  response regulator receiver sensor signal transduction histidine kinase  70.78 
 
 
613 aa  810    Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_011004  Rpal_5276  response regulator receiver sensor signal transduction histidine kinase  61.49 
 
 
579 aa  680    Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.606728  n/a   
 
 
-
 
NC_007643  Rru_A0131  response regulator receiver (CheY) and unknown domain-containing protein  46.75 
 
 
337 aa  248  2e-64  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0491  response regulator receiver modulated metal dependent phosphohydrolase  43.17 
 
 
522 aa  233  6e-60  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.165576  n/a   
 
 
-
 
NC_011138  MADE_03585  response regulator/GGDEF/EAL domain protein  39.38 
 
 
741 aa  228  3e-58  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_02571  response regulator  40.47 
 
 
521 aa  223  4.9999999999999996e-57  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_008228  Patl_4035  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  38.68 
 
 
746 aa  221  3.9999999999999997e-56  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.398097  n/a   
 
 
-
 
NC_008228  Patl_2561  response regulator receiver modulated metal dependent phosphohydrolase  35.48 
 
 
517 aa  218  2.9999999999999998e-55  Pseudoalteromonas atlantica T6c  Bacteria  hitchhiker  0.00356747  n/a   
 
 
-
 
NC_008751  Dvul_2247  response regulator receiver modulated metal dependent phosphohydrolase  40.29 
 
 
518 aa  216  9.999999999999999e-55  Desulfovibrio vulgaris DP4  Bacteria  normal  0.77168  normal 
 
 
-
 
NC_007519  Dde_3114  metal dependent phosphohydrolase  36.66 
 
 
523 aa  216  9.999999999999999e-55  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  hitchhiker  0.00390297  n/a   
 
 
-
 
NC_009052  Sbal_2012  response regulator receiver modulated metal dependent phosphohydrolase  39.43 
 
 
531 aa  214  2.9999999999999995e-54  Shewanella baltica OS155  Bacteria  normal  0.0999069  n/a   
 
 
-
 
NC_009831  Ssed_2209  response regulator receiver modulated metal dependent phosphohydrolase  36.42 
 
 
526 aa  211  3e-53  Shewanella sediminis HAW-EB3  Bacteria  normal  0.195398  normal 
 
 
-
 
NC_009052  Sbal_3786  response regulator receiver modulated metal dependent phosphohydrolase  38.36 
 
 
529 aa  206  8e-52  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0493  response regulator receiver modulated metal dependent phosphohydrolase  39.87 
 
 
531 aa  205  2e-51  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.366798  n/a   
 
 
-
 
NC_004347  SO_2366  response regulator  38.21 
 
 
525 aa  201  1.9999999999999998e-50  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_010506  Swoo_2427  response regulator receiver modulated metal dependent phosphohydrolase  34.78 
 
 
521 aa  201  3e-50  Shewanella woodyi ATCC 51908  Bacteria  normal  0.219655  hitchhiker  0.000118537 
 
 
-
 
NC_013173  Dbac_0215  response regulator receiver modulated metal dependent phosphohydrolase  37.91 
 
 
536 aa  201  3e-50  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_009035  Sbal_4485  hypothetical protein  37.13 
 
 
523 aa  201  3.9999999999999996e-50  Shewanella baltica OS155  Bacteria  n/a    n/a   
 
 
-
 
NC_009052  Sbal_2199  response regulator receiver modulated metal dependent phosphohydrolase  37.13 
 
 
523 aa  201  3.9999999999999996e-50  Shewanella baltica OS155  Bacteria  normal  0.179718  n/a   
 
 
-
 
NC_003910  CPS_0394  response regulator/GGDEF/EAL domain-containing protein  36.76 
 
 
740 aa  199  7.999999999999999e-50  Colwellia psychrerythraea 34H  Bacteria  normal  0.273558  n/a   
 
 
-
 
NC_009665  Shew185_2172  response regulator receiver modulated metal dependent phosphohydrolase  36.55 
 
 
523 aa  198  2.0000000000000003e-49  Shewanella baltica OS185  Bacteria  normal  0.0465103  n/a   
 
 
-
 
NC_011663  Sbal223_2212  response regulator receiver modulated metal dependent phosphohydrolase  36.55 
 
 
523 aa  198  2.0000000000000003e-49  Shewanella baltica OS223  Bacteria  normal  0.16257  normal  0.683218 
 
 
-
 
NC_009997  Sbal195_2222  response regulator receiver modulated metal dependent phosphohydrolase  36.55 
 
 
523 aa  198  2.0000000000000003e-49  Shewanella baltica OS195  Bacteria  normal  0.151758  normal  0.307874 
 
 
-
 
NC_008700  Sama_1789  response regulator receiver protein  36.73 
 
 
524 aa  197  3e-49  Shewanella amazonensis SB2B  Bacteria  normal  0.0101023  normal  0.210198 
 
 
-
 
NC_007643  Rru_A0659  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  40.37 
 
 
766 aa  197  5.000000000000001e-49  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_1361  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  37.67 
 
 
746 aa  196  7e-49  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_0496  putative diguanylate phosphodiesterase  34.11 
 
 
767 aa  196  1e-48  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.788805 
 
 
-
 
NC_008321  Shewmr4_2004  response regulator receiver modulated metal dependent phosphohydrolase  36.69 
 
 
525 aa  192  2e-47  Shewanella sp. MR-4  Bacteria  normal  0.0562345  hitchhiker  0.000000282251 
 
 
-
 
NC_008322  Shewmr7_1971  response regulator receiver modulated metal dependent phosphohydrolase  36.69 
 
 
525 aa  192  2e-47  Shewanella sp. MR-7  Bacteria  normal  0.0825869  normal  0.0109864 
 
 
-
 
NC_008577  Shewana3_2105  response regulator receiver modulated metal dependent phosphohydrolase  36.18 
 
 
525 aa  191  2.9999999999999997e-47  Shewanella sp. ANA-3  Bacteria  hitchhiker  0.00173233  normal  0.407049 
 
 
-
 
NC_009092  Shew_1983  response regulator receiver modulated metal dependent phosphohydrolase  34.49 
 
 
523 aa  188  2e-46  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00722808  normal 
 
 
-
 
NC_011663  Sbal223_1491  response regulator receiver modulated metal dependent phosphohydrolase  33.92 
 
 
513 aa  187  7e-46  Shewanella baltica OS223  Bacteria  normal  0.0411849  normal  0.405552 
 
 
-
 
NC_009665  Shew185_2885  response regulator receiver modulated metal dependent phosphohydrolase  33.92 
 
 
513 aa  187  7e-46  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_3014  response regulator receiver modulated metal dependent phosphohydrolase  33.92 
 
 
513 aa  187  7e-46  Shewanella baltica OS195  Bacteria  normal  normal  0.152382 
 
 
-
 
NC_009052  Sbal_2868  response regulator receiver modulated metal dependent phosphohydrolase  33.92 
 
 
513 aa  186  1.0000000000000001e-45  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_007954  Sden_1853  metal-dependent phosphohydrolase  35.9 
 
 
527 aa  184  5.0000000000000004e-45  Shewanella denitrificans OS217  Bacteria  normal  0.0219327  n/a   
 
 
-
 
NC_010002  Daci_3036  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  37.97 
 
 
758 aa  182  1e-44  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.830853 
 
 
-
 
NC_007954  Sden_2546  metal-dependent phosphohydrolase  32.29 
 
 
515 aa  181  2.9999999999999997e-44  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_2755  response regulator receiver modulated metal dependent phosphohydrolase  34.23 
 
 
520 aa  181  4.999999999999999e-44  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_009456  VC0395_1019  putative response regulator  37.24 
 
 
522 aa  179  1e-43  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_01215  Response regulator  32.11 
 
 
509 aa  170  6e-41  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.204793  n/a   
 
 
-
 
NC_007643  Rru_A0553  response regulator receiver Signal transduction histidine kinase  57.06 
 
 
440 aa  168  2e-40  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.580246  n/a   
 
 
-
 
NC_007912  Sde_3810  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  32.92 
 
 
763 aa  169  2e-40  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_013173  Dbac_0492  response regulator receiver modulated metal dependent phosphohydrolase  36.58 
 
 
508 aa  169  2e-40  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.0844408  n/a   
 
 
-
 
NC_008576  Mmc1_1813  response regulator receiver modulated metal dependent phosphohydrolase  34.11 
 
 
512 aa  164  4.0000000000000004e-39  Magnetococcus sp. MC-1  Bacteria  normal  0.0479529  normal  0.434013 
 
 
-
 
NC_009438  Sputcn32_1988  response regulator receiver modulated metal dependent phosphohydrolase  36.97 
 
 
437 aa  163  8.000000000000001e-39  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_009831  Ssed_1780  response regulator receiver modulated metal dependent phosphohydrolase  30.07 
 
 
525 aa  163  1e-38  Shewanella sediminis HAW-EB3  Bacteria  normal  0.33037  normal 
 
 
-
 
NC_013061  Phep_2551  ATP-binding region ATPase domain protein  38.49 
 
 
398 aa  163  1e-38  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_009052  Sbal_3403  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  32.92 
 
 
744 aa  159  1e-37  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_0967  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  33.23 
 
 
744 aa  159  1e-37  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_013501  Rmar_1190  histidine kinase  42.13 
 
 
646 aa  159  2e-37  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_009665  Shew185_0933  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  32.92 
 
 
744 aa  159  2e-37  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_0959  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  32.92 
 
 
744 aa  157  4e-37  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_0868  diguanylate cyclase/phosphodiesterase  34.46 
 
 
743 aa  157  7e-37  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_007643  Rru_A1908  response regulator receiver modulated diguanylate cyclase  52.73 
 
 
519 aa  154  4e-36  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.11693  n/a   
 
 
-
 
NC_007901  Rfer_4413  response regulator receiver sensor signal transduction histidine kinase  26.19 
 
 
565 aa  153  8.999999999999999e-36  Rhodoferax ferrireducens T118  Bacteria  n/a    n/a   
 
 
-
 
NC_008751  Dvul_0402  response regulator receiver sensor signal transduction histidine kinase  48.21 
 
 
398 aa  148  3e-34  Desulfovibrio vulgaris DP4  Bacteria  normal  0.93747  normal  0.145713 
 
 
-
 
NC_010571  Oter_1483  integral membrane sensor signal transduction histidine kinase  38.96 
 
 
477 aa  147  6e-34  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_008751  Dvul_2880  multi-sensor signal transduction histidine kinase  47.49 
 
 
576 aa  146  8.000000000000001e-34  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_009654  Mmwyl1_4383  response regulator receiver modulated diguanylate phosphodiesterase  31.77 
 
 
733 aa  146  1e-33  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_007796  Mhun_2689  multi-sensor signal transduction histidine kinase  34.94 
 
 
646 aa  141  3.9999999999999997e-32  Methanospirillum hungatei JF-1  Archaea  normal  normal  0.119288 
 
 
-
 
NC_013385  Adeg_1898  integral membrane sensor signal transduction histidine kinase  37.64 
 
 
546 aa  140  7e-32  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_009616  Tmel_0497  response regulator receiver modulated metal dependent phosphohydrolase  45.21 
 
 
432 aa  140  7e-32  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_013501  Rmar_2670  histidine kinase  36.19 
 
 
352 aa  139  1e-31  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_007614  Nmul_A1491  PAS/PAC sensor hybrid histidine kinase  35.16 
 
 
696 aa  139  1e-31  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.125145  n/a   
 
 
-
 
NC_010087  Bmul_5450  multi-sensor hybrid histidine kinase  37.61 
 
 
799 aa  139  1e-31  Burkholderia multivorans ATCC 17616  Bacteria  normal  hitchhiker  0.00754974 
 
 
-
 
NC_008340  Mlg_1802  GAF sensor signal transduction histidine kinase  32.53 
 
 
456 aa  139  1e-31  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal 
 
 
-
 
NC_011769  DvMF_1131  response regulator receiver sensor signal transduction histidine kinase  38.43 
 
 
500 aa  139  1e-31  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_010086  Bmul_4245  multi-sensor hybrid histidine kinase  39.08 
 
 
654 aa  139  2e-31  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_010571  Oter_0726  histidine kinase  34.36 
 
 
570 aa  139  2e-31  Opitutus terrae PB90-1  Bacteria  normal  0.408803  normal 
 
 
-
 
NC_008312  Tery_1418  GAF sensor hybrid histidine kinase  29.19 
 
 
853 aa  138  3.0000000000000003e-31  Trichodesmium erythraeum IMS101  Bacteria  normal  0.237881  normal 
 
 
-
 
NC_011661  Dtur_0748  GAF sensor signal transduction histidine kinase  35.63 
 
 
815 aa  137  7.000000000000001e-31  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_3856  response regulator receiver sensor signal transduction histidine kinase  38.3 
 
 
378 aa  136  9.999999999999999e-31  Opitutus terrae PB90-1  Bacteria  normal  normal  0.215089 
 
 
-
 
NC_009972  Haur_3937  GAF sensor signal transduction histidine kinase  37.85 
 
 
701 aa  135  1.9999999999999998e-30  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_006349  BMAA1979  sensory box histidine kinase/response regulator  38.1 
 
 
771 aa  135  1.9999999999999998e-30  Burkholderia mallei ATCC 23344  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_1289  sensory box histidine kinase/response regulator  38.1 
 
 
772 aa  135  1.9999999999999998e-30  Burkholderia mallei NCTC 10229  Bacteria  normal  n/a   
 
 
-
 
NC_008784  BMASAVP1_1000  sensory box histidine kinase/response regulator  38.1 
 
 
771 aa  135  1.9999999999999998e-30  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_009079  BMA10247_A2264  sensory box histidine kinase/response regulator  38.1 
 
 
771 aa  135  1.9999999999999998e-30  Burkholderia mallei NCTC 10247  Bacteria  normal  0.87596  n/a   
 
 
-
 
NC_007435  BURPS1710b_A1379  sensory box histidine kinase/response regulator  38.1 
 
 
769 aa  135  3e-30  Burkholderia pseudomallei 1710b  Bacteria  normal  0.364148  n/a   
 
 
-
 
NC_009075  BURPS668_A3159  sensory box histidine kinase/response regulator  37.66 
 
 
771 aa  134  6e-30  Burkholderia pseudomallei 668  Bacteria  normal  0.882119  n/a   
 
 
-
 
NC_009078  BURPS1106A_A3030  sensory box histidine kinase/response regulator  37.66 
 
 
771 aa  134  6e-30  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_3771  multi-sensor signal transduction histidine kinase  30.79 
 
 
1039 aa  134  6e-30  Roseiflexus sp. RS-1  Bacteria  normal  unclonable  0.0000191257 
 
 
-
 
NC_013161  Cyan8802_2814  GAF sensor hybrid histidine kinase  29.47 
 
 
763 aa  134  6e-30  Cyanothece sp. PCC 8802  Bacteria  normal  0.155467  normal  0.302046 
 
 
-
 
NC_011831  Cagg_0838  GAF sensor signal transduction histidine kinase  36.65 
 
 
461 aa  133  7.999999999999999e-30  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_3302  GAF sensor hybrid histidine kinase  29.47 
 
 
763 aa  133  7.999999999999999e-30  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_010814  Glov_0589  multi-sensor signal transduction histidine kinase  35.44 
 
 
581 aa  133  9e-30  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007519  Dde_0239  PAS/PAC sensor hybrid histidine kinase  44.75 
 
 
565 aa  133  9e-30  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_1027  integral membrane sensor signal transduction histidine kinase  29.39 
 
 
473 aa  133  9e-30  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_007509  Bcep18194_C7014  PAS/PAC sensor hybrid histidine kinase  35.9 
 
 
781 aa  132  1.0000000000000001e-29  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
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