More than 300 homologs were found in PanDaTox collection
for query gene Mext_2117 on replicon NC_010172
Organism: Methylobacterium extorquens PA1



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_007406  Nwi_3058  phage head-tail adaptor, putative  60.71 
 
 
580 aa  651    Nitrobacter winogradskyi Nb-255  Bacteria  decreased coverage  0.00943131  normal  0.0427518 
 
 
-
 
NC_010172  Mext_2117  histidine kinase  100 
 
 
631 aa  1259    Methylobacterium extorquens PA1  Bacteria  normal  normal  0.0208634 
 
 
-
 
NC_011004  Rpal_5276  response regulator receiver sensor signal transduction histidine kinase  60.17 
 
 
579 aa  671    Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.606728  n/a   
 
 
-
 
NC_011894  Mnod_1253  response regulator receiver sensor signal transduction histidine kinase  72.39 
 
 
584 aa  793    Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_2070  response regulator receiver sensor signal transduction histidine kinase  90.03 
 
 
613 aa  1078    Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_3287  response regulator receiver sensor signal transduction histidine kinase  76.6 
 
 
584 aa  864    Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.847642  normal 
 
 
-
 
NC_007778  RPB_4666  response regulator receiver sensor signal transduction histidine kinase  60.48 
 
 
578 aa  671    Rhodopseudomonas palustris HaA2  Bacteria  normal  normal 
 
 
-
 
NC_007925  RPC_0095  response regulator receiver sensor signal transduction histidine kinase  61.36 
 
 
582 aa  686    Rhodopseudomonas palustris BisB18  Bacteria  normal  normal 
 
 
-
 
NC_007958  RPD_4375  response regulator receiver sensor signal transduction histidine kinase  61.61 
 
 
550 aa  653    Rhodopseudomonas palustris BisB5  Bacteria  normal  normal 
 
 
-
 
NC_007964  Nham_3684  response regulator receiver sensor signal transduction histidine kinase  60.54 
 
 
580 aa  673    Nitrobacter hamburgensis X14  Bacteria  normal  0.896547  n/a   
 
 
-
 
NC_011757  Mchl_2394  response regulator receiver sensor signal transduction histidine kinase  99.33 
 
 
593 aa  1172    Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_1996  response regulator receiver sensor signal transduction histidine kinase  72.82 
 
 
584 aa  781    Methylobacterium sp. 4-46  Bacteria  normal  0.0327436  normal  0.170409 
 
 
-
 
NC_009485  BBta_0711  response regulator receiver sensor signal transduction histidine kinase  61.13 
 
 
581 aa  689    Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_007643  Rru_A0131  response regulator receiver (CheY) and unknown domain-containing protein  47.63 
 
 
337 aa  253  8.000000000000001e-66  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0491  response regulator receiver modulated metal dependent phosphohydrolase  40.4 
 
 
522 aa  239  1e-61  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.165576  n/a   
 
 
-
 
NC_008228  Patl_4035  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  38.75 
 
 
746 aa  234  5e-60  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.398097  n/a   
 
 
-
 
NC_011138  MADE_02571  response regulator  41.58 
 
 
521 aa  228  3e-58  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2247  response regulator receiver modulated metal dependent phosphohydrolase  41.61 
 
 
518 aa  225  2e-57  Desulfovibrio vulgaris DP4  Bacteria  normal  0.77168  normal 
 
 
-
 
NC_008700  Sama_1789  response regulator receiver protein  39.49 
 
 
524 aa  224  3e-57  Shewanella amazonensis SB2B  Bacteria  normal  0.0101023  normal  0.210198 
 
 
-
 
NC_009052  Sbal_2199  response regulator receiver modulated metal dependent phosphohydrolase  41.25 
 
 
523 aa  223  9e-57  Shewanella baltica OS155  Bacteria  normal  0.179718  n/a   
 
 
-
 
NC_009035  Sbal_4485  hypothetical protein  41.25 
 
 
523 aa  223  9e-57  Shewanella baltica OS155  Bacteria  n/a    n/a   
 
 
-
 
NC_004347  SO_2366  response regulator  40 
 
 
525 aa  222  1.9999999999999999e-56  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_008228  Patl_2561  response regulator receiver modulated metal dependent phosphohydrolase  37.43 
 
 
517 aa  221  3.9999999999999997e-56  Pseudoalteromonas atlantica T6c  Bacteria  hitchhiker  0.00356747  n/a   
 
 
-
 
NC_011138  MADE_03585  response regulator/GGDEF/EAL domain protein  39.69 
 
 
741 aa  219  1e-55  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_009665  Shew185_2172  response regulator receiver modulated metal dependent phosphohydrolase  40.59 
 
 
523 aa  218  2e-55  Shewanella baltica OS185  Bacteria  normal  0.0465103  n/a   
 
 
-
 
NC_011663  Sbal223_2212  response regulator receiver modulated metal dependent phosphohydrolase  40.59 
 
 
523 aa  218  2.9999999999999998e-55  Shewanella baltica OS223  Bacteria  normal  0.16257  normal  0.683218 
 
 
-
 
NC_009997  Sbal195_2222  response regulator receiver modulated metal dependent phosphohydrolase  40.59 
 
 
523 aa  218  2.9999999999999998e-55  Shewanella baltica OS195  Bacteria  normal  0.151758  normal  0.307874 
 
 
-
 
NC_008577  Shewana3_2105  response regulator receiver modulated metal dependent phosphohydrolase  39.17 
 
 
525 aa  218  4e-55  Shewanella sp. ANA-3  Bacteria  hitchhiker  0.00173233  normal  0.407049 
 
 
-
 
NC_008321  Shewmr4_2004  response regulator receiver modulated metal dependent phosphohydrolase  40.26 
 
 
525 aa  217  7e-55  Shewanella sp. MR-4  Bacteria  normal  0.0562345  hitchhiker  0.000000282251 
 
 
-
 
NC_008322  Shewmr7_1971  response regulator receiver modulated metal dependent phosphohydrolase  40.26 
 
 
525 aa  217  7e-55  Shewanella sp. MR-7  Bacteria  normal  0.0825869  normal  0.0109864 
 
 
-
 
NC_009831  Ssed_2209  response regulator receiver modulated metal dependent phosphohydrolase  38.28 
 
 
526 aa  213  5.999999999999999e-54  Shewanella sediminis HAW-EB3  Bacteria  normal  0.195398  normal 
 
 
-
 
NC_009052  Sbal_3786  response regulator receiver modulated metal dependent phosphohydrolase  37.34 
 
 
529 aa  213  7e-54  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0493  response regulator receiver modulated metal dependent phosphohydrolase  41.41 
 
 
531 aa  213  9e-54  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.366798  n/a   
 
 
-
 
NC_013173  Dbac_0215  response regulator receiver modulated metal dependent phosphohydrolase  40.06 
 
 
536 aa  212  2e-53  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_010506  Swoo_2427  response regulator receiver modulated metal dependent phosphohydrolase  38.28 
 
 
521 aa  208  2e-52  Shewanella woodyi ATCC 51908  Bacteria  normal  0.219655  hitchhiker  0.000118537 
 
 
-
 
NC_008700  Sama_0496  putative diguanylate phosphodiesterase  37.42 
 
 
767 aa  208  2e-52  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.788805 
 
 
-
 
NC_007519  Dde_3114  metal dependent phosphohydrolase  36.44 
 
 
523 aa  208  3e-52  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  hitchhiker  0.00390297  n/a   
 
 
-
 
NC_009052  Sbal_2012  response regulator receiver modulated metal dependent phosphohydrolase  38.05 
 
 
531 aa  207  5e-52  Shewanella baltica OS155  Bacteria  normal  0.0999069  n/a   
 
 
-
 
NC_009092  Shew_1983  response regulator receiver modulated metal dependent phosphohydrolase  38.85 
 
 
523 aa  203  7e-51  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00722808  normal 
 
 
-
 
NC_009665  Shew185_2885  response regulator receiver modulated metal dependent phosphohydrolase  35.22 
 
 
513 aa  203  8e-51  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_3014  response regulator receiver modulated metal dependent phosphohydrolase  35.22 
 
 
513 aa  203  8e-51  Shewanella baltica OS195  Bacteria  normal  normal  0.152382 
 
 
-
 
NC_003910  CPS_0394  response regulator/GGDEF/EAL domain-containing protein  35.54 
 
 
740 aa  203  9e-51  Colwellia psychrerythraea 34H  Bacteria  normal  0.273558  n/a   
 
 
-
 
NC_007643  Rru_A0659  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  40.43 
 
 
766 aa  203  9e-51  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_009052  Sbal_2868  response regulator receiver modulated metal dependent phosphohydrolase  34.49 
 
 
513 aa  202  9.999999999999999e-51  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_1491  response regulator receiver modulated metal dependent phosphohydrolase  35.22 
 
 
513 aa  202  9.999999999999999e-51  Shewanella baltica OS223  Bacteria  normal  0.0411849  normal  0.405552 
 
 
-
 
NC_007954  Sden_2546  metal-dependent phosphohydrolase  32.45 
 
 
515 aa  198  3e-49  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_1361  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  35.59 
 
 
746 aa  196  1e-48  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_007954  Sden_1853  metal-dependent phosphohydrolase  37.38 
 
 
527 aa  192  2e-47  Shewanella denitrificans OS217  Bacteria  normal  0.0219327  n/a   
 
 
-
 
NC_008345  Sfri_2755  response regulator receiver modulated metal dependent phosphohydrolase  34.12 
 
 
520 aa  188  3e-46  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_009456  VC0395_1019  putative response regulator  37.24 
 
 
522 aa  184  4.0000000000000006e-45  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_01215  Response regulator  34.09 
 
 
509 aa  182  2e-44  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.204793  n/a   
 
 
-
 
NC_013173  Dbac_0492  response regulator receiver modulated metal dependent phosphohydrolase  36.78 
 
 
508 aa  182  2e-44  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.0844408  n/a   
 
 
-
 
NC_007912  Sde_3810  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  34.29 
 
 
763 aa  180  8e-44  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_009831  Ssed_1780  response regulator receiver modulated metal dependent phosphohydrolase  32.26 
 
 
525 aa  175  1.9999999999999998e-42  Shewanella sediminis HAW-EB3  Bacteria  normal  0.33037  normal 
 
 
-
 
NC_007643  Rru_A0553  response regulator receiver Signal transduction histidine kinase  61.81 
 
 
440 aa  172  2e-41  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.580246  n/a   
 
 
-
 
NC_009438  Sputcn32_1988  response regulator receiver modulated metal dependent phosphohydrolase  39.53 
 
 
437 aa  172  2e-41  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_3036  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  36.36 
 
 
758 aa  171  4e-41  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.830853 
 
 
-
 
NC_008576  Mmc1_1813  response regulator receiver modulated metal dependent phosphohydrolase  34.09 
 
 
512 aa  167  5e-40  Magnetococcus sp. MC-1  Bacteria  normal  0.0479529  normal  0.434013 
 
 
-
 
NC_013061  Phep_2551  ATP-binding region ATPase domain protein  37.84 
 
 
398 aa  164  4.0000000000000004e-39  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_0868  diguanylate cyclase/phosphodiesterase  34.09 
 
 
743 aa  161  3e-38  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_007643  Rru_A1908  response regulator receiver modulated diguanylate cyclase  43.52 
 
 
519 aa  160  7e-38  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.11693  n/a   
 
 
-
 
NC_009997  Sbal195_0967  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  34.45 
 
 
744 aa  159  2e-37  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_011663  Sbal223_0959  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  34.11 
 
 
744 aa  159  2e-37  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_009665  Shew185_0933  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  34.11 
 
 
744 aa  158  3e-37  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009052  Sbal_3403  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  34.11 
 
 
744 aa  158  3e-37  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2880  multi-sensor signal transduction histidine kinase  46.74 
 
 
576 aa  150  1.0000000000000001e-34  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_007901  Rfer_4413  response regulator receiver sensor signal transduction histidine kinase  25.65 
 
 
565 aa  147  5e-34  Rhodoferax ferrireducens T118  Bacteria  n/a    n/a   
 
 
-
 
NC_009616  Tmel_0497  response regulator receiver modulated metal dependent phosphohydrolase  46.58 
 
 
432 aa  147  6e-34  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_0402  response regulator receiver sensor signal transduction histidine kinase  48.19 
 
 
398 aa  146  9e-34  Desulfovibrio vulgaris DP4  Bacteria  normal  0.93747  normal  0.145713 
 
 
-
 
NC_007519  Dde_0239  PAS/PAC sensor hybrid histidine kinase  30.32 
 
 
565 aa  145  2e-33  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_1483  integral membrane sensor signal transduction histidine kinase  34.31 
 
 
477 aa  145  3e-33  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_013501  Rmar_1190  histidine kinase  37.21 
 
 
646 aa  144  4e-33  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_013501  Rmar_2670  histidine kinase  35.64 
 
 
352 aa  144  4e-33  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_009654  Mmwyl1_4383  response regulator receiver modulated diguanylate phosphodiesterase  29.57 
 
 
733 aa  143  9.999999999999999e-33  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_009718  Fnod_1705  response regulator receiver modulated metal dependent phosphohydrolase  43.87 
 
 
471 aa  142  1.9999999999999998e-32  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  n/a   
 
 
-
 
NC_008752  Aave_2925  diguanylate cyclase/phosphodiesterase / diguanylate cyclase  32.97 
 
 
743 aa  141  3e-32  Acidovorax citrulli AAC00-1  Bacteria  normal  normal  0.249336 
 
 
-
 
NC_009675  Anae109_0539  multi-sensor hybrid histidine kinase  34.82 
 
 
816 aa  139  2e-31  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.146269  normal 
 
 
-
 
NC_013037  Dfer_5571  signal transduction histidine kinase with CheB and CheR activity  35.42 
 
 
1218 aa  138  4e-31  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.273526  normal 
 
 
-
 
NC_007796  Mhun_2689  multi-sensor signal transduction histidine kinase  35.82 
 
 
646 aa  137  5e-31  Methanospirillum hungatei JF-1  Archaea  normal  normal  0.119288 
 
 
-
 
NC_010571  Oter_3856  response regulator receiver sensor signal transduction histidine kinase  34.81 
 
 
378 aa  137  8e-31  Opitutus terrae PB90-1  Bacteria  normal  normal  0.215089 
 
 
-
 
NC_010086  Bmul_4245  multi-sensor hybrid histidine kinase  37.86 
 
 
654 aa  136  9.999999999999999e-31  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_0401  response regulator receiver sensor signal transduction histidine kinase  39.62 
 
 
415 aa  135  3e-30  Magnetococcus sp. MC-1  Bacteria  normal  normal  0.653943 
 
 
-
 
NC_008699  Noca_1933  ATPase domain-containing protein  36.89 
 
 
535 aa  134  3.9999999999999996e-30  Nocardioides sp. JS614  Bacteria  normal  0.493372  n/a   
 
 
-
 
NC_011769  DvMF_1131  response regulator receiver sensor signal transduction histidine kinase  36.17 
 
 
500 aa  134  6e-30  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_010508  Bcenmc03_1302  signal transduction histidine kinase with CheB and CheR activity  34.98 
 
 
1220 aa  134  6.999999999999999e-30  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.772751 
 
 
-
 
NC_007760  Adeh_3529  PAS/PAC sensor hybrid histidine kinase  37.41 
 
 
1088 aa  132  1.0000000000000001e-29  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_013204  Elen_1010  histidine kinase  33.68 
 
 
572 aa  132  2.0000000000000002e-29  Eggerthella lenta DSM 2243  Bacteria  normal  normal  0.0817847 
 
 
-
 
NC_010717  PXO_03078  sensor histidine kinase  34.94 
 
 
678 aa  132  2.0000000000000002e-29  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_0838  GAF sensor signal transduction histidine kinase  33.61 
 
 
461 aa  132  3e-29  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_007484  Noc_1601  CheB methylesterase, CheR methyltransferase, hybrid histidine kinase  34.4 
 
 
1222 aa  132  3e-29  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.472526  n/a   
 
 
-
 
NC_008554  Sfum_2006  integral membrane sensor signal transduction histidine kinase  35.63 
 
 
469 aa  131  3e-29  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_009078  BURPS1106A_A3030  sensory box histidine kinase/response regulator  36.29 
 
 
771 aa  129  2.0000000000000002e-28  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_008340  Mlg_1802  GAF sensor signal transduction histidine kinase  32.35 
 
 
456 aa  129  2.0000000000000002e-28  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal 
 
 
-
 
NC_009075  BURPS668_A3159  sensory box histidine kinase/response regulator  36.29 
 
 
771 aa  129  2.0000000000000002e-28  Burkholderia pseudomallei 668  Bacteria  normal  0.882119  n/a   
 
 
-
 
NC_008699  Noca_0194  ATPase domain-containing protein  34.85 
 
 
549 aa  129  2.0000000000000002e-28  Nocardioides sp. JS614  Bacteria  normal  0.357239  n/a   
 
 
-
 
NC_011369  Rleg2_1372  PAS/PAC sensor signal transduction histidine kinase  31.8 
 
 
510 aa  128  3e-28  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.94557  normal 
 
 
-
 
NC_010515  Bcenmc03_5978  PAS/PAC sensor hybrid histidine kinase  37.13 
 
 
656 aa  128  3e-28  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.410257  normal 
 
 
-
 
NC_013595  Sros_8765  Histidine kinase  35.88 
 
 
593 aa  128  3e-28  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_4352  multi-sensor hybrid histidine kinase  32.68 
 
 
1287 aa  128  3e-28  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.06083 
 
 
-
 
NC_010681  Bphyt_1282  PAS/PAC sensor signal transduction histidine kinase  35.65 
 
 
548 aa  128  3e-28  Burkholderia phytofirmans PsJN  Bacteria  normal  0.153514  normal  0.0403413 
 
 
-
 
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