More than 300 homologs were found in PanDaTox collection
for query gene Slin_5022 on replicon NC_013730
Organism: Spirosoma linguale DSM 74



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013730  Slin_5022  response regulator receiver protein  100 
 
 
126 aa  257  4e-68  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_1111  response regulator receiver protein  66.09 
 
 
123 aa  155  2e-37  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.0272953  normal  0.304596 
 
 
-
 
NC_013730  Slin_4603  response regulator receiver protein  59.82 
 
 
132 aa  128  3e-29  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_2799  response regulator receiver protein  55 
 
 
132 aa  125  2.0000000000000002e-28  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_0185  response regulator receiver protein  56.41 
 
 
132 aa  122  1e-27  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_5658  response regulator receiver protein  52.5 
 
 
132 aa  119  1.9999999999999998e-26  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.483341  normal 
 
 
-
 
NC_010511  M446_5294  response regulator receiver protein  51.67 
 
 
130 aa  116  9e-26  Methylobacterium sp. 4-46  Bacteria  normal  0.0717946  normal  0.338735 
 
 
-
 
NC_013730  Slin_5021  adenylate/guanylate cyclase  45.13 
 
 
348 aa  95.5  2e-19  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_1110  adenylate/guanylate cyclase  47.79 
 
 
348 aa  94.7  4e-19  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.0224811  normal  0.236606 
 
 
-
 
NC_010505  Mrad2831_5657  adenylate/guanylate cyclase  43.33 
 
 
421 aa  92.8  2e-18  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.517681  normal 
 
 
-
 
NC_010511  M446_2796  adenylate/guanylate cyclase  43.86 
 
 
447 aa  91.3  5e-18  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_5293  adenylate/guanylate cyclase  44.44 
 
 
421 aa  89  2e-17  Methylobacterium sp. 4-46  Bacteria  normal  0.0545376  normal  0.227088 
 
 
-
 
NC_008312  Tery_0615  response regulator receiver sensor signal transduction histidine kinase  41.59 
 
 
395 aa  85.1  3e-16  Trichodesmium erythraeum IMS101  Bacteria  normal  hitchhiker  0.00858549 
 
 
-
 
NC_009523  RoseRS_0337  response regulator receiver protein  37.5 
 
 
139 aa  84.7  4e-16  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.0132867 
 
 
-
 
NC_009767  Rcas_0846  response regulator receiver protein  36.67 
 
 
139 aa  83.6  9e-16  Roseiflexus castenholzii DSM 13941  Bacteria  normal  hitchhiker  0.00282438 
 
 
-
 
NC_013730  Slin_6047  response regulator receiver sensor hybrid histidine kinase  41.41 
 
 
677 aa  83.2  0.000000000000001  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_3177  adenylate/guanylate cyclase with GAF and PAS/PAC sensors  37.3 
 
 
971 aa  82.4  0.000000000000002  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_2396  response regulator receiver protein  37.19 
 
 
126 aa  81.6  0.000000000000003  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.612966  normal  0.464694 
 
 
-
 
NC_009767  Rcas_0993  response regulator receiver protein  38.52 
 
 
127 aa  79.7  0.00000000000001  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.250481  normal 
 
 
-
 
NC_013730  Slin_1905  response regulator receiver sensor hybrid histidine kinase  38.26 
 
 
668 aa  79  0.00000000000002  Spirosoma linguale DSM 74  Bacteria  normal  0.0295515  normal  0.210974 
 
 
-
 
NC_009675  Anae109_1951  two component, sigma54 specific, Fis family transcriptional regulator  35.88 
 
 
470 aa  79  0.00000000000002  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.516267  normal 
 
 
-
 
NC_002939  GSU1117  response regulator  39.84 
 
 
127 aa  78.6  0.00000000000003  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_3814  response regulator receiver protein  37.7 
 
 
127 aa  78.6  0.00000000000003  Roseiflexus sp. RS-1  Bacteria  normal  0.466742  normal  0.446242 
 
 
-
 
NC_007760  Adeh_1908  two component, sigma54 specific, Fis family transcriptional regulator  35.88 
 
 
473 aa  77.8  0.00000000000004  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_1971  two component, sigma54 specific, transcriptional regulator, Fis family  35.88 
 
 
473 aa  78.2  0.00000000000004  Anaeromyxobacter sp. K  Bacteria  normal  0.0887215  n/a   
 
 
-
 
NC_011891  A2cp1_2056  two component, sigma54 specific, transcriptional regulator, Fis family  35.88 
 
 
473 aa  78.2  0.00000000000004  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.732718  n/a   
 
 
-
 
NC_009972  Haur_2161  adenylate/guanylate cyclase with GAF sensor(s)  35 
 
 
1020 aa  77.8  0.00000000000005  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0428251  n/a   
 
 
-
 
NC_013730  Slin_4604  histidine kinase  38.94 
 
 
663 aa  77.4  0.00000000000006  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_0435  response regulator receiver protein  38.14 
 
 
124 aa  77  0.00000000000008  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00876892  n/a   
 
 
-
 
NC_009523  RoseRS_2694  putative PAS/PAC sensor protein  35.71 
 
 
969 aa  77  0.00000000000008  Roseiflexus sp. RS-1  Bacteria  normal  0.0176534  normal 
 
 
-
 
NC_002978  WD0221  response regulator PleD  36.29 
 
 
460 aa  76.3  0.0000000000001  Wolbachia endosymbiont of Drosophila melanogaster  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_4621  adenylate/guanylate cyclase  37.6 
 
 
687 aa  76.3  0.0000000000002  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.828122 
 
 
-
 
NC_007517  Gmet_2679  response regulator receiver domain-containing protein  37.4 
 
 
129 aa  75.9  0.0000000000002  Geobacter metallireducens GS-15  Bacteria  normal  0.380915  normal  0.27601 
 
 
-
 
NC_008554  Sfum_2806  two component, sigma54 specific, Fis family transcriptional regulator  37.17 
 
 
450 aa  75.9  0.0000000000002  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_2453  two component, sigma54 specific, Fis family transcriptional regulator  33.9 
 
 
461 aa  75.1  0.0000000000003  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0000196128  normal 
 
 
-
 
NC_008554  Sfum_0648  response regulator receiver protein  36.07 
 
 
151 aa  75.5  0.0000000000003  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_011830  Dhaf_4841  response regulator receiver protein  36.8 
 
 
118 aa  75.1  0.0000000000003  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.202718  n/a   
 
 
-
 
NC_009439  Pmen_3647  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  36.07 
 
 
715 aa  75.5  0.0000000000003  Pseudomonas mendocina ymp  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_2281  response regulator receiver protein  34.88 
 
 
128 aa  74.7  0.0000000000004  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.498531 
 
 
-
 
NC_009483  Gura_2934  response regulator receiver protein  39.02 
 
 
129 aa  73.6  0.0000000000009  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000852899  n/a   
 
 
-
 
NC_011884  Cyan7425_2205  multi-sensor hybrid histidine kinase  36.07 
 
 
887 aa  73.6  0.000000000001  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.188088 
 
 
-
 
NC_011769  DvMF_2550  multi-sensor signal transduction histidine kinase  36.97 
 
 
685 aa  73.2  0.000000000001  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_011666  Msil_0424  response regulator receiver modulated diguanylate cyclase  35.48 
 
 
469 aa  73.2  0.000000000001  Methylocella silvestris BL2  Bacteria  n/a    normal  0.97349 
 
 
-
 
NC_008781  Pnap_1073  multi-sensor hybrid histidine kinase  36.22 
 
 
1158 aa  73.2  0.000000000001  Polaromonas naphthalenivorans CJ2  Bacteria  hitchhiker  0.00830683  normal  0.406928 
 
 
-
 
NC_010002  Daci_1192  response regulator receiver modulated diguanylate cyclase  38.33 
 
 
316 aa  72  0.000000000002  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_0885  response regulator receiver protein  36.92 
 
 
127 aa  72.4  0.000000000002  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.123702  hitchhiker  0.00202919 
 
 
-
 
NC_007519  Dde_0321  response regulator receiver domain-containing protein  33.33 
 
 
122 aa  72.4  0.000000000002  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_1807  response regulator receiver protein  35.25 
 
 
139 aa  72.8  0.000000000002  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_013162  Coch_1562  histidine kinase  35.2 
 
 
1296 aa  72.4  0.000000000002  Capnocytophaga ochracea DSM 7271  Bacteria  normal  0.655639  n/a   
 
 
-
 
NC_008740  Maqu_1999  two component, sigma54 specific, Fis family transcriptional regulator  38.79 
 
 
481 aa  72  0.000000000002  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_3603  response regulator receiver protein  35.83 
 
 
131 aa  72  0.000000000002  Geobacter lovleyi SZ  Bacteria  normal  0.656399  n/a   
 
 
-
 
NC_011831  Cagg_1597  adenylate/guanylate cyclase with GAF sensor(s)  36.28 
 
 
981 aa  72.4  0.000000000002  Chloroflexus aggregans DSM 9485  Bacteria  unclonable  0.000711164  normal 
 
 
-
 
NC_009943  Dole_0427  two component, sigma54 specific, Fis family transcriptional regulator  37.5 
 
 
458 aa  71.6  0.000000000003  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_1042  two component signal transduction response regulator  38.33 
 
 
465 aa  72  0.000000000003  Pelobacter carbinolicus DSM 2380  Bacteria  normal  0.472622  n/a   
 
 
-
 
NC_011769  DvMF_1991  response regulator receiver protein  36.07 
 
 
153 aa  72  0.000000000003  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_013161  Cyan8802_4348  CheA signal transduction histidine kinase  37.27 
 
 
911 aa  71.6  0.000000000003  Cyanothece sp. PCC 8802  Bacteria  normal  normal  0.485697 
 
 
-
 
NC_011726  PCC8801_4288  CheA signal transduction histidine kinase  37.27 
 
 
911 aa  71.6  0.000000000003  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013061  Phep_2648  response regulator receiver  32 
 
 
1363 aa  72  0.000000000003  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_008554  Sfum_0821  response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase  39.83 
 
 
1139 aa  72  0.000000000003  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal  0.187038 
 
 
-
 
NC_008709  Ping_3328  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  35.25 
 
 
711 aa  72  0.000000000003  Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_007498  Pcar_2017  response regulator CheY  34.96 
 
 
129 aa  71.2  0.000000000004  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007519  Dde_1723  response regulator receiver (CheY-like) modulated serine phosphatase  34.17 
 
 
381 aa  71.2  0.000000000004  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  hitchhiker  0.00833768  n/a   
 
 
-
 
NC_008576  Mmc1_1726  putative PAS/PAC sensor protein  32.77 
 
 
504 aa  71.2  0.000000000004  Magnetococcus sp. MC-1  Bacteria  normal  0.0909206  normal  0.287685 
 
 
-
 
NC_007404  Tbd_0904  two component Fis family transcriptional regulator  42.11 
 
 
454 aa  71.2  0.000000000005  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  0.629928  normal 
 
 
-
 
NC_008554  Sfum_0618  response regulator receiver protein  34.71 
 
 
157 aa  71.2  0.000000000005  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_013422  Hneap_0133  response regulator receiver modulated diguanylate cyclase  39.13 
 
 
461 aa  70.9  0.000000000006  Halothiobacillus neapolitanus c2  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_2463  response regulator receiver modulated diguanylate cyclase  36.59 
 
 
301 aa  70.9  0.000000000006  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_010524  Lcho_3967  CheA signal transduction histidine kinase  42.2 
 
 
2414 aa  70.9  0.000000000006  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0139967 
 
 
-
 
NC_009485  BBta_1737  two component transcriptional regulator  33.33 
 
 
243 aa  70.5  0.000000000007  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.151372  normal  0.336316 
 
 
-
 
NC_010338  Caul_0283  response regulator receiver protein  36.64 
 
 
129 aa  70.5  0.000000000007  Caulobacter sp. K31  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_0605  adenylate/guanylate cyclase  32.82 
 
 
355 aa  70.5  0.000000000008  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.657653  n/a   
 
 
-
 
NC_007498  Pcar_2345  two component signal transduction response regulator  37.29 
 
 
455 aa  70.1  0.000000000009  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.00459366  n/a   
 
 
-
 
NC_011662  Tmz1t_1843  two component, sigma54 specific, transcriptional regulator, Fis family  39.66 
 
 
465 aa  70.1  0.000000000009  Thauera sp. MZ1T  Bacteria  normal  0.798265  n/a   
 
 
-
 
NC_011757  Mchl_0452  response regulator receiver protein  37.01 
 
 
127 aa  69.3  0.00000000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.0577794  normal  0.205923 
 
 
-
 
NC_013173  Dbac_2272  response regulator receiver sensor signal transduction histidine kinase  38.14 
 
 
382 aa  70.1  0.00000000001  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.275022  n/a   
 
 
-
 
NC_012918  GM21_0684  two component, sigma54 specific, transcriptional regulator, Fis family  36.07 
 
 
469 aa  69.7  0.00000000001  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.0000000000150794 
 
 
-
 
NC_011146  Gbem_1660  response regulator receiver protein  38.21 
 
 
126 aa  69.7  0.00000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_013525  Tter_1135  two component transcriptional regulator, winged helix family  33.6 
 
 
227 aa  70.1  0.00000000001  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_012918  GM21_2553  response regulator receiver protein  38.21 
 
 
126 aa  69.7  0.00000000001  Geobacter sp. M21  Bacteria  n/a    hitchhiker  2.1194499999999997e-20 
 
 
-
 
NC_013223  Dret_2370  response regulator receiver modulated metal dependent phosphohydrolase  34.71 
 
 
370 aa  69.7  0.00000000001  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0489  response regulator receiver protein  37.01 
 
 
127 aa  69.3  0.00000000001  Methylobacterium populi BJ001  Bacteria  normal  normal  0.514722 
 
 
-
 
NC_010172  Mext_0419  response regulator receiver  37.01 
 
 
127 aa  69.3  0.00000000001  Methylobacterium extorquens PA1  Bacteria  normal  0.487855  normal  0.449259 
 
 
-
 
NC_011884  Cyan7425_4747  CheA signal transduction histidine kinase  34.78 
 
 
941 aa  69.7  0.00000000001  Cyanothece sp. PCC 7425  Bacteria  normal  hitchhiker  0.0000159984 
 
 
-
 
NC_010814  Glov_3153  response regulator receiver sensor signal transduction histidine kinase  34.45 
 
 
366 aa  68.9  0.00000000002  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4156  two component transcriptional regulator  37.72 
 
 
232 aa  69.3  0.00000000002  Herpetosiphon aurantiacus ATCC 23779  Bacteria  decreased coverage  0.0000307056  n/a   
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  33.87 
 
 
235 aa  69.3  0.00000000002  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_013223  Dret_0410  anti-sigma-factor antagonist  37.7 
 
 
238 aa  68.9  0.00000000002  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal  0.694521 
 
 
-
 
NC_007796  Mhun_1438  putative PAS/PAC sensor protein  37.5 
 
 
393 aa  69.3  0.00000000002  Methanospirillum hungatei JF-1  Archaea  normal  normal  0.92182 
 
 
-
 
NC_007912  Sde_2163  response regulator receiver domain-containing protein  36.51 
 
 
128 aa  69.3  0.00000000002  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_4907  putative response regulator in two-component reguatory system, sigma54 dependent transcriptional regulator  35 
 
 
452 aa  69.3  0.00000000002  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.412473 
 
 
-
 
NC_008345  Sfri_4005  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  32.5 
 
 
696 aa  68.9  0.00000000002  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_45620  two-component response regulator CheY  34.88 
 
 
124 aa  68.9  0.00000000002  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.028564  normal  0.20809 
 
 
-
 
NC_008576  Mmc1_1217  multi-sensor hybrid histidine kinase  35 
 
 
803 aa  68.9  0.00000000002  Magnetococcus sp. MC-1  Bacteria  normal  0.503931  normal  0.0882093 
 
 
-
 
NC_013173  Dbac_0628  two component, sigma54 specific, transcriptional regulator, Fis family  34.43 
 
 
446 aa  69.3  0.00000000002  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0313  response regulator receiver protein  33.88 
 
 
143 aa  68.9  0.00000000002  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.0254543  n/a   
 
 
-
 
NC_008740  Maqu_1974  response regulator receiver protein  34.88 
 
 
127 aa  68.9  0.00000000002  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2827  response regulator receiver protein  38.33 
 
 
137 aa  68.9  0.00000000002  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_011138  MADE_01756  Response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase)  34.45 
 
 
337 aa  68.9  0.00000000002  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.844049  n/a   
 
 
-
 
NC_010524  Lcho_3464  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  34.15 
 
 
704 aa  68.9  0.00000000002  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.140727 
 
 
-
 
NC_013223  Dret_2392  two component, sigma54 specific, transcriptional regulator, Fis family  37.5 
 
 
458 aa  69.3  0.00000000002  Desulfohalobium retbaense DSM 5692  Bacteria  normal  0.0321511  normal 
 
 
-
 
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