More than 300 homologs were found in PanDaTox collection
for query gene Slin_4603 on replicon NC_013730
Organism: Spirosoma linguale DSM 74



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013730  Slin_4603  response regulator receiver protein  100 
 
 
132 aa  271  3e-72  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_5022  response regulator receiver protein  60.32 
 
 
126 aa  144  4.0000000000000006e-34  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_1111  response regulator receiver protein  60.53 
 
 
123 aa  142  2e-33  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.0272953  normal  0.304596 
 
 
-
 
NC_010511  M446_0185  response regulator receiver protein  49.58 
 
 
132 aa  110  5e-24  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010505  Mrad2831_5657  adenylate/guanylate cyclase  50.81 
 
 
421 aa  109  1.0000000000000001e-23  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.517681  normal 
 
 
-
 
NC_010505  Mrad2831_5658  response regulator receiver protein  47.9 
 
 
132 aa  104  4e-22  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.483341  normal 
 
 
-
 
NC_010511  M446_2799  response regulator receiver protein  47.06 
 
 
132 aa  104  5e-22  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_1110  adenylate/guanylate cyclase  49.58 
 
 
348 aa  103  5e-22  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.0224811  normal  0.236606 
 
 
-
 
NC_013730  Slin_5021  adenylate/guanylate cyclase  47.06 
 
 
348 aa  102  1e-21  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_5294  response regulator receiver protein  45.38 
 
 
130 aa  103  1e-21  Methylobacterium sp. 4-46  Bacteria  normal  0.0717946  normal  0.338735 
 
 
-
 
NC_010511  M446_2796  adenylate/guanylate cyclase  44.35 
 
 
447 aa  95.5  2e-19  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_5293  adenylate/guanylate cyclase  45.97 
 
 
421 aa  92  2e-18  Methylobacterium sp. 4-46  Bacteria  normal  0.0545376  normal  0.227088 
 
 
-
 
NC_008312  Tery_0615  response regulator receiver sensor signal transduction histidine kinase  44.54 
 
 
395 aa  91.3  4e-18  Trichodesmium erythraeum IMS101  Bacteria  normal  hitchhiker  0.00858549 
 
 
-
 
NC_013730  Slin_6047  response regulator receiver sensor hybrid histidine kinase  41.09 
 
 
677 aa  91.3  5e-18  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_4621  adenylate/guanylate cyclase  43.33 
 
 
687 aa  88.2  3e-17  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.828122 
 
 
-
 
NC_013730  Slin_4604  histidine kinase  42.52 
 
 
663 aa  86.7  1e-16  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_1114  response regulator receiver modulated serine phosphatase  45.37 
 
 
391 aa  85.1  3e-16  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_4840  two-component response regulator PilR  41.32 
 
 
448 aa  84  6e-16  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.43512  normal  0.760188 
 
 
-
 
NC_013501  Rmar_0513  two component transcriptional regulator, winged helix family  37.69 
 
 
228 aa  84  7e-16  Rhodothermus marinus DSM 4252  Bacteria  normal  0.985837  n/a   
 
 
-
 
NC_009483  Gura_2934  response regulator receiver protein  39.37 
 
 
129 aa  83.2  0.000000000000001  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000852899  n/a   
 
 
-
 
NC_002978  WD0221  response regulator PleD  41.32 
 
 
460 aa  82.4  0.000000000000002  Wolbachia endosymbiont of Drosophila melanogaster  Bacteria  normal  n/a   
 
 
-
 
NC_010524  Lcho_0380  two component, sigma54 specific, Fis family transcriptional regulator  40.87 
 
 
522 aa  82.8  0.000000000000002  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0200588 
 
 
-
 
NC_011761  AFE_0027  sigma-54 dependent transcriptional regulator/response regulator  35.16 
 
 
455 aa  82  0.000000000000002  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  n/a   
 
 
-
 
NC_011206  Lferr_0029  two component, sigma54 specific, transcriptional regulator, Fis family  35.16 
 
 
455 aa  82  0.000000000000002  Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  0.59486  normal  0.125276 
 
 
-
 
NC_007517  Gmet_2453  two component, sigma54 specific, Fis family transcriptional regulator  34.45 
 
 
461 aa  80.5  0.000000000000007  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0000196128  normal 
 
 
-
 
NC_013730  Slin_1905  response regulator receiver sensor hybrid histidine kinase  36.43 
 
 
668 aa  80.5  0.000000000000007  Spirosoma linguale DSM 74  Bacteria  normal  0.0295515  normal  0.210974 
 
 
-
 
NC_012918  GM21_2553  response regulator receiver protein  39.37 
 
 
126 aa  80.1  0.00000000000001  Geobacter sp. M21  Bacteria  n/a    hitchhiker  2.1194499999999997e-20 
 
 
-
 
NC_011146  Gbem_1660  response regulator receiver protein  39.37 
 
 
126 aa  80.1  0.00000000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU1117  response regulator  37.5 
 
 
127 aa  79.3  0.00000000000002  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_1971  two component, sigma54 specific, transcriptional regulator, Fis family  37.07 
 
 
473 aa  79  0.00000000000002  Anaeromyxobacter sp. K  Bacteria  normal  0.0887215  n/a   
 
 
-
 
NC_010814  Glov_3603  response regulator receiver protein  37.72 
 
 
131 aa  79.3  0.00000000000002  Geobacter lovleyi SZ  Bacteria  normal  0.656399  n/a   
 
 
-
 
NC_008740  Maqu_1999  two component, sigma54 specific, Fis family transcriptional regulator  34.11 
 
 
481 aa  79  0.00000000000002  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_2056  two component, sigma54 specific, transcriptional regulator, Fis family  37.07 
 
 
473 aa  79  0.00000000000002  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.732718  n/a   
 
 
-
 
NC_010814  Glov_3153  response regulator receiver sensor signal transduction histidine kinase  37.61 
 
 
366 aa  79  0.00000000000002  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_0504  two component, sigma54 specific, Fis family transcriptional regulator  35.48 
 
 
443 aa  78.2  0.00000000000003  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_1908  two component, sigma54 specific, Fis family transcriptional regulator  37.07 
 
 
473 aa  78.6  0.00000000000003  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_0533  two component, sigma54 specific, transcriptional regulator, Fis family  35.48 
 
 
443 aa  77.4  0.00000000000005  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.141325  n/a   
 
 
-
 
NC_011145  AnaeK_0537  two component, sigma54 specific, transcriptional regulator, Fis family  35.48 
 
 
446 aa  77.4  0.00000000000006  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_2382  CheA signal transduction histidine kinase  39.25 
 
 
679 aa  77.4  0.00000000000006  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_2679  response regulator receiver domain-containing protein  35.83 
 
 
129 aa  77.4  0.00000000000007  Geobacter metallireducens GS-15  Bacteria  normal  0.380915  normal  0.27601 
 
 
-
 
NC_011831  Cagg_2396  response regulator receiver protein  34.92 
 
 
126 aa  77  0.00000000000008  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.612966  normal  0.464694 
 
 
-
 
NC_008554  Sfum_2764  two component, sigma54 specific, Fis family transcriptional regulator  42.24 
 
 
466 aa  77  0.00000000000008  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_008781  Pnap_1073  multi-sensor hybrid histidine kinase  40.16 
 
 
1158 aa  77  0.00000000000009  Polaromonas naphthalenivorans CJ2  Bacteria  hitchhiker  0.00830683  normal  0.406928 
 
 
-
 
NC_009675  Anae109_1951  two component, sigma54 specific, Fis family transcriptional regulator  37.07 
 
 
470 aa  76.3  0.0000000000001  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.516267  normal 
 
 
-
 
NC_009483  Gura_4220  response regulator receiver protein  38.66 
 
 
120 aa  75.9  0.0000000000002  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2581  sigma-54 dependent transcriptional regulator  47.67 
 
 
456 aa  75.5  0.0000000000002  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_011126  HY04AAS1_0193  response regulator receiver protein  34.96 
 
 
127 aa  75.5  0.0000000000002  Hydrogenobaculum sp. Y04AAS1  Bacteria  hitchhiker  0.00528064  n/a   
 
 
-
 
NC_004578  PSPTO_0823  type 4 fimbriae expression regulatory protein pilR  38.6 
 
 
446 aa  75.9  0.0000000000002  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_0662  helix-turn-helix, Fis-type  36.15 
 
 
451 aa  75.9  0.0000000000002  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007947  Mfla_0214  two component, sigma54 specific, Fis family transcriptional regulator  40.71 
 
 
455 aa  75.9  0.0000000000002  Methylobacillus flagellatus KT  Bacteria  normal  normal  0.662344 
 
 
-
 
NC_009656  PSPA7_5187  two-component response regulator PilR  39.47 
 
 
445 aa  75.9  0.0000000000002  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_0548  two component, sigma54 specific, transcriptional regulator, Fis family  38.74 
 
 
452 aa  75.5  0.0000000000002  Desulfohalobium retbaense DSM 5692  Bacteria  normal  0.902927  normal 
 
 
-
 
NC_008346  Swol_2412  response regulator receiver protein  33.33 
 
 
123 aa  75.9  0.0000000000002  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.18168  n/a   
 
 
-
 
NC_008463  PA14_60260  two-component response regulator PilR  39.47 
 
 
445 aa  75.9  0.0000000000002  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  hitchhiker  0.000000831057 
 
 
-
 
NC_011666  Msil_0424  response regulator receiver modulated diguanylate cyclase  35.54 
 
 
469 aa  75.9  0.0000000000002  Methylocella silvestris BL2  Bacteria  n/a    normal  0.97349 
 
 
-
 
NC_008825  Mpe_A3216  type IV pilus expression regulatory protein  37.07 
 
 
537 aa  76.3  0.0000000000002  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.422678 
 
 
-
 
NC_013440  Hoch_2281  response regulator receiver protein  32.8 
 
 
128 aa  75.9  0.0000000000002  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.498531 
 
 
-
 
NC_008599  CFF8240_1193  diguanylate cyclase  36.36 
 
 
415 aa  75.5  0.0000000000002  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  n/a   
 
 
-
 
NC_009802  CCC13826_0443  lipoprotein  38.71 
 
 
121 aa  74.7  0.0000000000003  Campylobacter concisus 13826  Bacteria  normal  0.81181  n/a   
 
 
-
 
NC_007005  Psyr_0722  helix-turn-helix, Fis-type  38.6 
 
 
445 aa  75.1  0.0000000000003  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_009092  Shew_0981  response regulator receiver protein  36.67 
 
 
155 aa  75.1  0.0000000000003  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_013223  Dret_0970  two component, sigma54 specific, transcriptional regulator, Fis family  36.67 
 
 
473 aa  75.1  0.0000000000003  Desulfohalobium retbaense DSM 5692  Bacteria  normal  0.0157817  hitchhiker  0.00000223455 
 
 
-
 
NC_008554  Sfum_3111  two component, sigma54 specific, Fis family transcriptional regulator  37.82 
 
 
458 aa  75.1  0.0000000000003  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_0435  response regulator receiver protein  35.48 
 
 
124 aa  74.7  0.0000000000003  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00876892  n/a   
 
 
-
 
NC_008709  Ping_3328  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  34.17 
 
 
711 aa  75.1  0.0000000000003  Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_0853  two component transcriptional regulator, AraC family  37.93 
 
 
509 aa  74.7  0.0000000000004  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_010338  Caul_0283  response regulator receiver protein  36.29 
 
 
129 aa  74.3  0.0000000000004  Caulobacter sp. K31  Bacteria  normal  normal 
 
 
-
 
NC_008752  Aave_0866  two component, sigma54 specific, Fis family transcriptional regulator  37.5 
 
 
496 aa  74.7  0.0000000000004  Acidovorax citrulli AAC00-1  Bacteria  normal  0.555974  normal  0.133337 
 
 
-
 
NC_013173  Dbac_0628  two component, sigma54 specific, transcriptional regulator, Fis family  36.43 
 
 
446 aa  74.7  0.0000000000004  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_008554  Sfum_0821  response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase  40.34 
 
 
1139 aa  74.7  0.0000000000004  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal  0.187038 
 
 
-
 
NC_012918  GM21_1836  CheA signal transduction histidine kinase  38.32 
 
 
679 aa  74.7  0.0000000000004  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.00846455 
 
 
-
 
NC_009715  CCV52592_1198  putative chemotaxis protein CheY-like protein  38.71 
 
 
139 aa  74.3  0.0000000000005  Campylobacter curvus 525.92  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2039  two component, sigma54 specific, Fis family transcriptional regulator  38.53 
 
 
476 aa  73.9  0.0000000000007  Desulfovibrio vulgaris DP4  Bacteria  normal  0.238588  normal 
 
 
-
 
NC_013124  Afer_0558  two component transcriptional regulator, winged helix family  34.62 
 
 
237 aa  73.6  0.0000000000008  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_3323  two component, sigma54 specific, transcriptional regulator, Fis family  38.74 
 
 
458 aa  73.6  0.0000000000008  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.581416  n/a   
 
 
-
 
NC_010814  Glov_3076  two component, sigma54 specific, transcriptional regulator, Fis family  33.33 
 
 
454 aa  73.6  0.0000000000009  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_0653  two-component response regulator PhoB  34.45 
 
 
230 aa  73.6  0.0000000000009  Pelobacter carbinolicus DSM 2380  Bacteria  normal  0.131558  n/a   
 
 
-
 
NC_009675  Anae109_2379  two component, sigma54 specific, Fis family transcriptional regulator  36 
 
 
446 aa  73.6  0.0000000000009  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.373235  normal  0.0399931 
 
 
-
 
NC_014230  CA2559_08281  two component, sigma54 specific, transcriptional regulator, Fis family protein  36.36 
 
 
388 aa  73.6  0.0000000000009  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_01756  Response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase)  34.19 
 
 
337 aa  72.8  0.000000000001  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.844049  n/a   
 
 
-
 
NC_002939  GSU1320  sigma-54 dependent DNA-binding response regulator  33.9 
 
 
460 aa  73.2  0.000000000001  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_3929  response regulator receiver protein  36.89 
 
 
120 aa  72.8  0.000000000001  Geobacter sp. M21  Bacteria  n/a    normal  0.0321819 
 
 
-
 
NC_010814  Glov_2298  two component, sigma54 specific, transcriptional regulator, Fis family  35.2 
 
 
452 aa  72.8  0.000000000001  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007406  Nwi_1432  response regulator PleD  34.71 
 
 
457 aa  72.8  0.000000000001  Nitrobacter winogradskyi Nb-255  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_2845  two component transcriptional regulator, winged helix family  33.59 
 
 
234 aa  73.2  0.000000000001  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_009972  Haur_0605  adenylate/guanylate cyclase  33.9 
 
 
355 aa  72.8  0.000000000001  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.657653  n/a   
 
 
-
 
NC_007908  Rfer_2738  response regulator receiver domain-containing protein  38.79 
 
 
194 aa  73.2  0.000000000001  Rhodoferax ferrireducens T118  Bacteria  hitchhiker  0.000186206  n/a   
 
 
-
 
NC_007908  Rfer_3345  two component, sigma54 specific, Fis family transcriptional regulator  35.65 
 
 
483 aa  72.8  0.000000000001  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_0677  response regulator receiver modulated metal dependent phosphohydrolase  39.64 
 
 
343 aa  73.2  0.000000000001  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.756866  n/a   
 
 
-
 
NC_011146  Gbem_3845  response regulator receiver protein  36.89 
 
 
120 aa  73.2  0.000000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_4322  two component, sigma54 specific, Fis family transcriptional regulator  40.74 
 
 
444 aa  72.4  0.000000000002  Pseudomonas putida F1  Bacteria  normal  0.713581  normal 
 
 
-
 
NC_009707  JJD26997_0603  chemotaxis protein CheY  36.72 
 
 
130 aa  72.4  0.000000000002  Campylobacter jejuni subsp. doylei 269.97  Bacteria  normal  n/a   
 
 
-
 
NC_010581  Bind_3627  response regulator receiver protein  37.82 
 
 
129 aa  72.8  0.000000000002  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal  0.0857805 
 
 
-
 
NC_007355  Mbar_A3109  response regulator receiver  36.67 
 
 
285 aa  72.4  0.000000000002  Methanosarcina barkeri str. Fusaro  Archaea  normal  0.0893452  normal  0.677049 
 
 
-
 
NC_007498  Pcar_1042  two component signal transduction response regulator  38.89 
 
 
465 aa  72  0.000000000002  Pelobacter carbinolicus DSM 2380  Bacteria  normal  0.472622  n/a   
 
 
-
 
NC_011769  DvMF_1131  response regulator receiver sensor signal transduction histidine kinase  36.36 
 
 
500 aa  72.8  0.000000000002  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_008787  CJJ81176_1136  chemotaxis protein CheY  36.72 
 
 
130 aa  72.4  0.000000000002  Campylobacter jejuni subsp. jejuni 81-176  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_2510  two component, sigma54 specific, transcriptional regulator, Fis family  36.45 
 
 
472 aa  72  0.000000000002  Haliangium ochraceum DSM 14365  Bacteria  normal  0.0791346  normal 
 
 
-
 
NC_008751  Dvul_2709  response regulator receiver sensor signal transduction histidine kinase  37.61 
 
 
501 aa  72  0.000000000002  Desulfovibrio vulgaris DP4  Bacteria  normal  0.710197  normal  0.745824 
 
 
-
 
NC_009504  BOV_A0575  response regulator PleD  34.71 
 
 
456 aa  72.4  0.000000000002  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
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