More than 300 homologs were found in PanDaTox collection
for query gene Mext_0459 on replicon NC_010172
Organism: Methylobacterium extorquens PA1



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010172  Mext_0459  response regulator receiver  100 
 
 
176 aa  350  7e-96  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.493555 
 
 
-
 
NC_010172  Mext_3509  metal-dependent phosphohydrolase  91.33 
 
 
351 aa  314  4e-85  Methylobacterium extorquens PA1  Bacteria  normal  0.305053  normal 
 
 
-
 
NC_011757  Mchl_3816  response regulator receiver modulated metal dependent phosphohydrolase  91.33 
 
 
351 aa  313  7e-85  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.0960158  normal 
 
 
-
 
NC_010725  Mpop_3894  response regulator receiver modulated metal dependent phosphohydrolase  90.17 
 
 
353 aa  313  7e-85  Methylobacterium populi BJ001  Bacteria  normal  0.0109719  normal  0.416002 
 
 
-
 
NC_011757  Mchl_0538  response regulator receiver modulated metal dependent phosphohydrolase  90.75 
 
 
363 aa  313  8e-85  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.973232  normal 
 
 
-
 
NC_010511  M446_5359  response regulator receiver modulated metal dependent phosphohydrolase  71.1 
 
 
347 aa  240  7.999999999999999e-63  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.0670454 
 
 
-
 
NC_010505  Mrad2831_2085  response regulator receiver modulated metal dependent phosphohydrolase  64.74 
 
 
345 aa  204  4e-52  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.931733  normal  0.012958 
 
 
-
 
NC_012850  Rleg_3169  response regulator receiver modulated metal dependent phosphohydrolase  47.4 
 
 
353 aa  144  7.0000000000000006e-34  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.821118  normal 
 
 
-
 
NC_007298  Daro_2902  response regulator receiver  38.82 
 
 
350 aa  123  1e-27  Dechloromonas aromatica RCB  Bacteria  normal  0.1984  normal  0.246098 
 
 
-
 
NC_011662  Tmz1t_1183  response regulator receiver modulated metal dependent phosphohydrolase  41.62 
 
 
363 aa  122  2e-27  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011901  Tgr7_0081  two component transcriptional regulator, AraC family  41.38 
 
 
399 aa  122  2e-27  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_0148  response regulator receiver modulated metal dependent phosphohydrolase  46.85 
 
 
385 aa  122  3e-27  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.750781  n/a   
 
 
-
 
NC_007947  Mfla_2655  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  39.18 
 
 
353 aa  118  3.9999999999999996e-26  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_0150  response regulator receiver modulated metal dependent phosphohydrolase  41.04 
 
 
369 aa  112  2.0000000000000002e-24  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.245203 
 
 
-
 
NC_010172  Mext_0206  metal-dependent phosphohydrolase  41.04 
 
 
369 aa  112  2.0000000000000002e-24  Methylobacterium extorquens PA1  Bacteria  normal  0.44114  normal  0.760724 
 
 
-
 
NC_011989  Avi_0523  Response regulator protein  38.01 
 
 
359 aa  112  3e-24  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_010717  PXO_00070  Two-component system response regulator RpfG  40.85 
 
 
353 aa  111  5e-24  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.0844737  n/a   
 
 
-
 
NC_007404  Tbd_2670  metal dependent phosphohydrolase, HD region  44.3 
 
 
344 aa  110  2.0000000000000002e-23  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_0838  response regulator receiver modulated metal dependent phosphohydrolase  42.05 
 
 
378 aa  110  2.0000000000000002e-23  Methylobacterium sp. 4-46  Bacteria  normal  0.8404  normal 
 
 
-
 
NC_010505  Mrad2831_1613  response regulator receiver modulated metal dependent phosphohydrolase  46.67 
 
 
487 aa  108  5e-23  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.350204  hitchhiker  0.000130728 
 
 
-
 
NC_011071  Smal_1828  response regulator receiver modulated metal dependent phosphohydrolase  40.14 
 
 
379 aa  101  6e-21  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.723665 
 
 
-
 
NC_011989  Avi_4319  Metal dependent phosphohydrolase with a response regulator receiver protein  38.15 
 
 
382 aa  97.4  1e-19  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_010577  XfasM23_0399  response regulator receiver modulated metal dependent phosphohydrolase  34.71 
 
 
384 aa  97.1  1e-19  Xylella fastidiosa M23  Bacteria  normal  n/a   
 
 
-
 
NC_010513  Xfasm12_0458  response regulator receiver protein  37.76 
 
 
384 aa  96.7  2e-19  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2017  response regulator receiver modulated metal dependent phosphohydrolase  29.21 
 
 
379 aa  86.7  1e-16  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.98115  n/a   
 
 
-
 
NC_009943  Dole_1136  response regulator receiver modulated metal dependent phosphohydrolase  32.75 
 
 
348 aa  84.7  6e-16  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_009901  Spea_0629  response regulator receiver modulated metal dependent phosphohydrolase  32.57 
 
 
339 aa  82.8  0.000000000000002  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2574  response regulator  35.03 
 
 
368 aa  82  0.000000000000004  Geobacter sulfurreducens PCA  Bacteria  normal  0.482084  n/a   
 
 
-
 
NC_009665  Shew185_0836  response regulator receiver modulated metal dependent phosphohydrolase  32.37 
 
 
338 aa  80.1  0.00000000000001  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009052  Sbal_3504  response regulator receiver modulated metal dependent phosphohydrolase  32.37 
 
 
338 aa  80.1  0.00000000000001  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_0859  response regulator receiver modulated metal dependent phosphohydrolase  32.37 
 
 
338 aa  80.1  0.00000000000001  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_009997  Sbal195_0871  response regulator receiver modulated metal dependent phosphohydrolase  32.37 
 
 
338 aa  80.1  0.00000000000002  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_009092  Shew_3199  response regulator receiver modulated metal dependent phosphohydrolase  32.57 
 
 
339 aa  79.3  0.00000000000003  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_004347  SO_0860  response regulator  31.43 
 
 
339 aa  78.2  0.00000000000006  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_008321  Shewmr4_0716  response regulator receiver modulated metal dependent phosphohydrolase  31.43 
 
 
338 aa  78.2  0.00000000000006  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3306  response regulator receiver modulated metal dependent phosphohydrolase  31.43 
 
 
338 aa  78.2  0.00000000000006  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_3418  response regulator receiver modulated metal dependent phosphohydrolase  31.43 
 
 
338 aa  78.2  0.00000000000006  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_2951  response regulator receiver protein  31.21 
 
 
340 aa  78.2  0.00000000000006  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.129077 
 
 
-
 
NC_009438  Sputcn32_3141  response regulator receiver modulated metal dependent phosphohydrolase  31.21 
 
 
338 aa  77.8  0.00000000000008  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU1891  response regulator  33.33 
 
 
379 aa  77  0.0000000000001  Geobacter sulfurreducens PCA  Bacteria  normal  0.750204  n/a   
 
 
-
 
NC_013522  Taci_1739  response regulator receiver modulated metal dependent phosphohydrolase  32.26 
 
 
362 aa  76.6  0.0000000000002  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  0.0711596  n/a   
 
 
-
 
NC_010725  Mpop_4963  response regulator receiver modulated metal dependent phosphohydrolase  39.52 
 
 
350 aa  76.6  0.0000000000002  Methylobacterium populi BJ001  Bacteria  normal  0.102256  normal  0.0892849 
 
 
-
 
NC_007484  Noc_0847  two component diguanylate cyclase  34.53 
 
 
327 aa  74.3  0.0000000000008  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_008782  Ajs_1044  response regulator receiver modulated metal dependent phosphohydrolase  32.95 
 
 
377 aa  74.3  0.0000000000008  Acidovorax sp. JS42  Bacteria  normal  normal  0.0516082 
 
 
-
 
NC_011894  Mnod_5340  response regulator receiver modulated metal dependent phosphohydrolase  40.52 
 
 
348 aa  73.6  0.000000000002  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.64097  n/a   
 
 
-
 
NC_013216  Dtox_4196  response regulator receiver modulated metal dependent phosphohydrolase  32.48 
 
 
350 aa  73.6  0.000000000002  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_011992  Dtpsy_0962  response regulator receiver modulated metal dependent phosphohydrolase  33.33 
 
 
377 aa  73.2  0.000000000002  Acidovorax ebreus TPSY  Bacteria  normal  0.115091  n/a   
 
 
-
 
NC_010581  Bind_1213  response regulator receiver modulated diguanylate cyclase  35.63 
 
 
457 aa  72.4  0.000000000003  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_007802  Jann_3131  response regulator receiver modulated diguanylate cyclase  35.94 
 
 
464 aa  72.4  0.000000000003  Jannaschia sp. CCS1  Bacteria  normal  normal  0.308445 
 
 
-
 
NC_010511  M446_6679  response regulator receiver modulated diguanylate cyclase  49.33 
 
 
457 aa  72.4  0.000000000003  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_008044  TM1040_2887  response regulator receiver modulated serine phosphatase  36.75 
 
 
423 aa  72.4  0.000000000003  Ruegeria sp. TM1040  Bacteria  normal  normal 
 
 
-
 
NC_010524  Lcho_3464  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  37.5 
 
 
704 aa  72.4  0.000000000003  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.140727 
 
 
-
 
NC_008576  Mmc1_3165  response regulator receiver modulated metal dependent phosphohydrolase  30 
 
 
367 aa  72.4  0.000000000003  Magnetococcus sp. MC-1  Bacteria  normal  0.0569095  normal  0.0154692 
 
 
-
 
NC_010511  M446_5034  response regulator receiver modulated metal dependent phosphohydrolase  39.66 
 
 
348 aa  72.8  0.000000000003  Methylobacterium sp. 4-46  Bacteria  normal  0.749308  hitchhiker  0.00297277 
 
 
-
 
NC_011757  Mchl_0931  response regulator receiver modulated diguanylate cyclase  40.91 
 
 
457 aa  72  0.000000000004  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.436852  normal  0.104843 
 
 
-
 
NC_010172  Mext_0967  diguanylate cyclase  40.91 
 
 
457 aa  72  0.000000000004  Methylobacterium extorquens PA1  Bacteria  normal  0.555277  normal  0.0207283 
 
 
-
 
NC_011883  Ddes_1054  response regulator receiver modulated metal dependent phosphohydrolase  30.29 
 
 
359 aa  72  0.000000000004  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  n/a   
 
 
-
 
NC_011989  Avi_1750  response regulator PleD  44.3 
 
 
457 aa  71.6  0.000000000005  Agrobacterium vitis S4  Bacteria  normal  0.263569  n/a   
 
 
-
 
NC_003910  CPS_4164  response regulator/phosphatase  29.71 
 
 
352 aa  72  0.000000000005  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_1474  response regulator receiver modulated metal dependent phosphohydrolase  33.58 
 
 
345 aa  71.6  0.000000000005  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011894  Mnod_7417  response regulator receiver modulated diguanylate cyclase  49.33 
 
 
457 aa  71.6  0.000000000005  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.196799  n/a   
 
 
-
 
NC_011146  Gbem_0799  response regulator receiver protein  29.24 
 
 
225 aa  72  0.000000000005  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_007511  Bcep18194_B2092  adenylate/guanylate cyclase  32.48 
 
 
395 aa  71.6  0.000000000006  Burkholderia sp. 383  Bacteria  normal  0.498255  normal  0.305178 
 
 
-
 
NC_013223  Dret_2370  response regulator receiver modulated metal dependent phosphohydrolase  33.71 
 
 
370 aa  70.9  0.000000000008  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_007575  Suden_1924  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  30.28 
 
 
367 aa  70.9  0.000000000009  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.620973  n/a   
 
 
-
 
NC_007925  RPC_4677  response regulator receiver domain-containing protein  35.29 
 
 
121 aa  70.9  0.000000000009  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal 
 
 
-
 
NC_008254  Meso_1348  response regulator PleD  43.75 
 
 
457 aa  70.9  0.000000000009  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_008347  Mmar10_1277  response regulator receiver modulated diguanylate cyclase  37.9 
 
 
454 aa  70.9  0.000000000009  Maricaulis maris MCS10  Bacteria  normal  0.410696  normal  0.0388481 
 
 
-
 
NC_008752  Aave_2064  response regulator receiver modulated metal dependent phosphohydrolase  31.98 
 
 
395 aa  70.5  0.00000000001  Acidovorax citrulli AAC00-1  Bacteria  normal  0.18463  normal  0.544249 
 
 
-
 
NC_012918  GM21_0846  response regulator receiver protein  30.26 
 
 
225 aa  70.1  0.00000000001  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007348  Reut_B4068  response regulator receiver  33.81 
 
 
377 aa  70.5  0.00000000001  Ralstonia eutropha JMP134  Bacteria  normal  0.706307  n/a   
 
 
-
 
NC_011369  Rleg2_1290  response regulator PleD  34.56 
 
 
457 aa  70.5  0.00000000001  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.0138689  hitchhiker  0.00259394 
 
 
-
 
NC_007614  Nmul_A1861  putative PAS/PAC sensor protein  31.19 
 
 
280 aa  70.1  0.00000000001  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.372386  n/a   
 
 
-
 
NC_009719  Plav_2815  response regulator receiver modulated diguanylate cyclase  36.36 
 
 
457 aa  70.5  0.00000000001  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.631579  normal  0.0857187 
 
 
-
 
NC_007908  Rfer_3546  putative PAS/PAC sensor protein  29.33 
 
 
282 aa  70.5  0.00000000001  Rhodoferax ferrireducens T118  Bacteria  normal  0.536601  n/a   
 
 
-
 
NC_010814  Glov_1546  response regulator receiver modulated metal dependent phosphohydrolase  31.64 
 
 
368 aa  70.5  0.00000000001  Geobacter lovleyi SZ  Bacteria  normal  0.61009  n/a   
 
 
-
 
NC_010814  Glov_3523  response regulator receiver modulated metal dependent phosphohydrolase  32.59 
 
 
363 aa  70.5  0.00000000001  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_009831  Ssed_3915  response regulator receiver modulated metal dependent phosphohydrolase  27.33 
 
 
356 aa  70.1  0.00000000002  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_011666  Msil_0424  response regulator receiver modulated diguanylate cyclase  48.78 
 
 
469 aa  70.1  0.00000000002  Methylocella silvestris BL2  Bacteria  n/a    normal  0.97349 
 
 
-
 
NC_014148  Plim_0679  response regulator receiver  30.11 
 
 
337 aa  70.1  0.00000000002  Planctomyces limnophilus DSM 3776  Bacteria  normal  0.0836964  n/a   
 
 
-
 
NC_011004  Rpal_0146  response regulator receiver protein  36.47 
 
 
121 aa  70.1  0.00000000002  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_008576  Mmc1_3408  response regulator receiver modulated metal dependent phosphohydrolase  31.18 
 
 
346 aa  69.3  0.00000000002  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_010338  Caul_1497  response regulator PleD  40.68 
 
 
454 aa  69.3  0.00000000002  Caulobacter sp. K31  Bacteria  normal  normal  0.122959 
 
 
-
 
NC_004578  PSPTO_1278  sensory box protein/response regulator  35.35 
 
 
705 aa  68.9  0.00000000004  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.517683  n/a   
 
 
-
 
NC_007005  Psyr_1098  PAS:GGDEF  36.19 
 
 
705 aa  68.6  0.00000000005  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_011901  Tgr7_0506  adenylate/guanylate cyclase  34.92 
 
 
380 aa  68.2  0.00000000005  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  0.149903  n/a   
 
 
-
 
NC_010681  Bphyt_0187  response regulator receiver modulated metal dependent phosphohydrolase  34.68 
 
 
354 aa  68.6  0.00000000005  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.0125166 
 
 
-
 
NC_010725  Mpop_0907  response regulator receiver modulated diguanylate cyclase  43.82 
 
 
457 aa  68.2  0.00000000005  Methylobacterium populi BJ001  Bacteria  normal  0.401363  normal  0.40647 
 
 
-
 
NC_012850  Rleg_1382  response regulator PleD  39.39 
 
 
457 aa  68.2  0.00000000006  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.390598 
 
 
-
 
NC_010505  Mrad2831_1864  response regulator receiver modulated diguanylate cyclase  46.67 
 
 
457 aa  68.2  0.00000000006  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.831894  normal  0.121309 
 
 
-
 
NC_007955  Mbur_1899  multisensor signal transduction histidine kinase  33.55 
 
 
462 aa  68.2  0.00000000006  Methanococcoides burtonii DSM 6242  Archaea  normal  0.970297  n/a   
 
 
-
 
NC_007413  Ava_1562  response regulator receiver Signal transduction histidine kinase  31.34 
 
 
369 aa  67.8  0.00000000007  Anabaena variabilis ATCC 29413  Bacteria  normal  0.847548  normal  0.236297 
 
 
-
 
NC_007614  Nmul_A1860  diguanylate cyclase  31.3 
 
 
312 aa  67.8  0.00000000007  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_1139  response regulator receiver  43.28 
 
 
121 aa  67.8  0.00000000008  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_4270  response regulator receiver modulated metal dependent phosphohydrolase  32.53 
 
 
361 aa  67.8  0.00000000008  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_008700  Sama_0065  response regulator receiver protein  31.85 
 
 
305 aa  67.4  0.00000000009  Shewanella amazonensis SB2B  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_1573  response regulator receiver protein  39.53 
 
 
121 aa  67  0.0000000001  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.146471 
 
 
-
 
NC_011666  Msil_1887  adenylate/guanylate cyclase  34.48 
 
 
403 aa  67.4  0.0000000001  Methylocella silvestris BL2  Bacteria  n/a    normal  0.522729 
 
 
-
 
NC_009092  Shew_3790  response regulator receiver modulated diguanylate cyclase  30.65 
 
 
300 aa  66.6  0.0000000002  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0080  response regulator receiver modulated metal dependent phosphohydrolase  31.07 
 
 
357 aa  66.6  0.0000000002  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
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