More than 300 homologs were found in PanDaTox collection
for query gene M446_5034 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010511  M446_5034  response regulator receiver modulated metal dependent phosphohydrolase  100 
 
 
348 aa  679    Methylobacterium sp. 4-46  Bacteria  normal  0.749308  hitchhiker  0.00297277 
 
 
-
 
NC_011894  Mnod_5340  response regulator receiver modulated metal dependent phosphohydrolase  83.05 
 
 
348 aa  571  1.0000000000000001e-162  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.64097  n/a   
 
 
-
 
NC_010725  Mpop_4963  response regulator receiver modulated metal dependent phosphohydrolase  57.56 
 
 
350 aa  348  1e-94  Methylobacterium populi BJ001  Bacteria  normal  0.102256  normal  0.0892849 
 
 
-
 
NC_011757  Mchl_4913  response regulator receiver modulated metal dependent phosphohydrolase  56.01 
 
 
354 aa  330  3e-89  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.478904  normal  0.760596 
 
 
-
 
NC_010172  Mext_4449  metal-dependent phosphohydrolase  56.14 
 
 
358 aa  329  5.0000000000000004e-89  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.508967 
 
 
-
 
NC_011757  Mchl_0538  response regulator receiver modulated metal dependent phosphohydrolase  46.88 
 
 
363 aa  277  2e-73  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.973232  normal 
 
 
-
 
NC_011757  Mchl_3816  response regulator receiver modulated metal dependent phosphohydrolase  46.55 
 
 
351 aa  274  2.0000000000000002e-72  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.0960158  normal 
 
 
-
 
NC_010172  Mext_3509  metal-dependent phosphohydrolase  46.55 
 
 
351 aa  273  4.0000000000000004e-72  Methylobacterium extorquens PA1  Bacteria  normal  0.305053  normal 
 
 
-
 
NC_010511  M446_5359  response regulator receiver modulated metal dependent phosphohydrolase  54.84 
 
 
347 aa  273  4.0000000000000004e-72  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.0670454 
 
 
-
 
NC_010725  Mpop_3894  response regulator receiver modulated metal dependent phosphohydrolase  51.6 
 
 
353 aa  271  9e-72  Methylobacterium populi BJ001  Bacteria  normal  0.0109719  normal  0.416002 
 
 
-
 
NC_010505  Mrad2831_2085  response regulator receiver modulated metal dependent phosphohydrolase  52.84 
 
 
345 aa  265  1e-69  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.931733  normal  0.012958 
 
 
-
 
NC_011004  Rpal_0148  response regulator receiver modulated metal dependent phosphohydrolase  46.5 
 
 
385 aa  238  9e-62  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.750781  n/a   
 
 
-
 
NC_010511  M446_0838  response regulator receiver modulated metal dependent phosphohydrolase  43.83 
 
 
378 aa  238  2e-61  Methylobacterium sp. 4-46  Bacteria  normal  0.8404  normal 
 
 
-
 
NC_012850  Rleg_3169  response regulator receiver modulated metal dependent phosphohydrolase  45.39 
 
 
353 aa  234  1.0000000000000001e-60  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.821118  normal 
 
 
-
 
NC_011901  Tgr7_0081  two component transcriptional regulator, AraC family  48.07 
 
 
399 aa  234  2.0000000000000002e-60  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_1183  response regulator receiver modulated metal dependent phosphohydrolase  42.96 
 
 
363 aa  229  6e-59  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_010172  Mext_0206  metal-dependent phosphohydrolase  44.29 
 
 
369 aa  229  7e-59  Methylobacterium extorquens PA1  Bacteria  normal  0.44114  normal  0.760724 
 
 
-
 
NC_011757  Mchl_0150  response regulator receiver modulated metal dependent phosphohydrolase  44.29 
 
 
369 aa  229  7e-59  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.245203 
 
 
-
 
NC_010505  Mrad2831_1613  response regulator receiver modulated metal dependent phosphohydrolase  45.67 
 
 
487 aa  226  3e-58  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.350204  hitchhiker  0.000130728 
 
 
-
 
NC_007404  Tbd_2670  metal dependent phosphohydrolase, HD region  45.74 
 
 
344 aa  226  7e-58  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_011989  Avi_0523  Response regulator protein  43.34 
 
 
359 aa  224  2e-57  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011989  Avi_4319  Metal dependent phosphohydrolase with a response regulator receiver protein  43.49 
 
 
382 aa  222  7e-57  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2902  response regulator receiver  41.92 
 
 
350 aa  222  8e-57  Dechloromonas aromatica RCB  Bacteria  normal  0.1984  normal  0.246098 
 
 
-
 
NC_007947  Mfla_2655  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  38.87 
 
 
353 aa  212  7.999999999999999e-54  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_010717  PXO_00070  Two-component system response regulator RpfG  43.71 
 
 
353 aa  203  3e-51  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.0844737  n/a   
 
 
-
 
NC_007520  Tcr_1911  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  42.02 
 
 
268 aa  202  7e-51  Thiomicrospira crunogena XCL-2  Bacteria  normal  0.0445959  n/a   
 
 
-
 
NC_010681  Bphyt_0187  response regulator receiver modulated metal dependent phosphohydrolase  40.88 
 
 
354 aa  201  1.9999999999999998e-50  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.0125166 
 
 
-
 
NC_007298  Daro_0007  response regulator receiver modulated metal dependent phosphohydrolase  37.8 
 
 
379 aa  200  3.9999999999999996e-50  Dechloromonas aromatica RCB  Bacteria  normal  0.829613  normal  0.0284762 
 
 
-
 
NC_013216  Dtox_4196  response regulator receiver modulated metal dependent phosphohydrolase  38.95 
 
 
350 aa  199  5e-50  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_008321  Shewmr4_0792  response regulator receiver modulated metal dependent phosphohydrolase  33.63 
 
 
331 aa  198  1.0000000000000001e-49  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3231  response regulator receiver modulated metal dependent phosphohydrolase  33.63 
 
 
331 aa  198  1.0000000000000001e-49  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_0479  response regulator receiver modulated metal dependent phosphohydrolase  37.09 
 
 
350 aa  197  3e-49  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_012560  Avin_25160  response regulator  36.1 
 
 
356 aa  196  4.0000000000000005e-49  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_008321  Shewmr4_0481  response regulator receiver modulated metal dependent phosphohydrolase  35.82 
 
 
348 aa  196  6e-49  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_3334  response regulator receiver modulated metal dependent phosphohydrolase  41.49 
 
 
331 aa  196  7e-49  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_010506  Swoo_3313  response regulator receiver modulated metal dependent phosphohydrolase  40 
 
 
343 aa  196  7e-49  Shewanella woodyi ATCC 51908  Bacteria  normal  hitchhiker  0.00000482447 
 
 
-
 
NC_011071  Smal_1828  response regulator receiver modulated metal dependent phosphohydrolase  39.68 
 
 
379 aa  195  8.000000000000001e-49  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.723665 
 
 
-
 
NC_007954  Sden_3723  response regulator receiver  39.6 
 
 
338 aa  192  5e-48  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_008322  Shewmr7_3549  response regulator receiver modulated metal dependent phosphohydrolase  35.22 
 
 
348 aa  193  5e-48  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_009654  Mmwyl1_1086  response regulator receiver modulated metal dependent phosphohydrolase  37.05 
 
 
331 aa  192  7e-48  Marinomonas sp. MWYL1  Bacteria  normal  0.226857  hitchhiker  0.0000000112469 
 
 
-
 
NC_010577  XfasM23_0399  response regulator receiver modulated metal dependent phosphohydrolase  38.73 
 
 
384 aa  191  1e-47  Xylella fastidiosa M23  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_2545  metal dependent phosphohydrolase  51.98 
 
 
269 aa  192  1e-47  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_009831  Ssed_3915  response regulator receiver modulated metal dependent phosphohydrolase  32.56 
 
 
356 aa  191  2e-47  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_010513  Xfasm12_0458  response regulator receiver protein  38.73 
 
 
384 aa  191  2e-47  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2017  response regulator receiver modulated metal dependent phosphohydrolase  33.33 
 
 
379 aa  191  2e-47  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.98115  n/a   
 
 
-
 
NC_008576  Mmc1_3408  response regulator receiver modulated metal dependent phosphohydrolase  35.95 
 
 
346 aa  191  2e-47  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_008228  Patl_2248  response regulator receiver modulated metal dependent phosphohydrolase  42.55 
 
 
331 aa  190  2.9999999999999997e-47  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_50640  response regulator with metal dependent phosphohydrolase activity (two-component)  37.62 
 
 
347 aa  189  8e-47  Azotobacter vinelandii DJ  Bacteria  normal  0.121542  n/a   
 
 
-
 
NC_002939  GSU1891  response regulator  38.15 
 
 
379 aa  188  1e-46  Geobacter sulfurreducens PCA  Bacteria  normal  0.750204  n/a   
 
 
-
 
NC_010002  Daci_6015  response regulator receiver modulated metal dependent phosphohydrolase  36.34 
 
 
333 aa  188  1e-46  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_009438  Sputcn32_3141  response regulator receiver modulated metal dependent phosphohydrolase  37.8 
 
 
338 aa  188  1e-46  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_2505  response regulator receiver modulated metal dependent phosphohydrolase  34.57 
 
 
331 aa  188  2e-46  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_010506  Swoo_3823  response regulator receiver modulated metal dependent phosphohydrolase  32.9 
 
 
354 aa  186  4e-46  Shewanella woodyi ATCC 51908  Bacteria  normal  normal 
 
 
-
 
NC_008010  Dgeo_2833  metal dependent phosphohydrolase  49.78 
 
 
379 aa  185  1.0000000000000001e-45  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.0209293  n/a   
 
 
-
 
NC_008577  Shewana3_3418  response regulator receiver modulated metal dependent phosphohydrolase  37.8 
 
 
338 aa  185  1.0000000000000001e-45  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_1474  response regulator receiver modulated metal dependent phosphohydrolase  37.41 
 
 
345 aa  184  2.0000000000000003e-45  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_008321  Shewmr4_0716  response regulator receiver modulated metal dependent phosphohydrolase  37.46 
 
 
338 aa  184  2.0000000000000003e-45  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3306  response regulator receiver modulated metal dependent phosphohydrolase  37.46 
 
 
338 aa  184  2.0000000000000003e-45  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_004347  SO_0860  response regulator  37.11 
 
 
339 aa  184  3e-45  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_009901  Spea_0629  response regulator receiver modulated metal dependent phosphohydrolase  36.79 
 
 
339 aa  184  3e-45  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_008700  Sama_2951  response regulator receiver protein  37.24 
 
 
340 aa  184  3e-45  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.129077 
 
 
-
 
NC_013946  Mrub_1382  diguanylate cyclase and serine/threonine protein kinase with TPR repeats  51.85 
 
 
868 aa  183  4.0000000000000006e-45  Meiothermus ruber DSM 1279  Bacteria  normal  0.0126588  normal  0.259783 
 
 
-
 
NC_009654  Mmwyl1_0356  response regulator receiver modulated metal dependent phosphohydrolase  37.55 
 
 
360 aa  182  6e-45  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_009997  Sbal195_0871  response regulator receiver modulated metal dependent phosphohydrolase  36.08 
 
 
338 aa  182  7e-45  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_009052  Sbal_3504  response regulator receiver modulated metal dependent phosphohydrolase  34.94 
 
 
338 aa  182  8.000000000000001e-45  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_0859  response regulator receiver modulated metal dependent phosphohydrolase  34.94 
 
 
338 aa  182  8.000000000000001e-45  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_009665  Shew185_0836  response regulator receiver modulated metal dependent phosphohydrolase  34.94 
 
 
338 aa  182  8.000000000000001e-45  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009092  Shew_3199  response regulator receiver modulated metal dependent phosphohydrolase  34.72 
 
 
339 aa  181  1e-44  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_0863  response regulator receiver modulated metal dependent phosphohydrolase  37.02 
 
 
351 aa  181  2e-44  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.297515  normal  0.141829 
 
 
-
 
NC_013552  DhcVS_1406  response regulator  39.16 
 
 
351 aa  180  2.9999999999999997e-44  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_008576  Mmc1_3165  response regulator receiver modulated metal dependent phosphohydrolase  35.02 
 
 
367 aa  179  5.999999999999999e-44  Magnetococcus sp. MC-1  Bacteria  normal  0.0569095  normal  0.0154692 
 
 
-
 
NC_008700  Sama_3111  response regulator receiver protein  34.07 
 
 
328 aa  178  9e-44  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.0637882 
 
 
-
 
NC_004347  SO_4003  response regulator  35.76 
 
 
357 aa  177  2e-43  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_011138  MADE_01756  Response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase)  32.61 
 
 
337 aa  177  3e-43  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.844049  n/a   
 
 
-
 
NC_008740  Maqu_3676  response regulator receiver modulated metal dependent phosphohydrolase  34.49 
 
 
328 aa  177  3e-43  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_3285  response regulator receiver  38.95 
 
 
362 aa  176  4e-43  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0080  response regulator receiver modulated metal dependent phosphohydrolase  39.23 
 
 
357 aa  175  9.999999999999999e-43  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_03429  two-component system response regulator (hybrid family) protein  33.93 
 
 
358 aa  174  1.9999999999999998e-42  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_3523  response regulator receiver modulated metal dependent phosphohydrolase  42.24 
 
 
363 aa  174  1.9999999999999998e-42  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2138  metal dependent phosphohydrolase  42.79 
 
 
606 aa  174  2.9999999999999996e-42  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.258694  n/a   
 
 
-
 
NC_012918  GM21_0063  response regulator receiver modulated metal dependent phosphohydrolase  39.23 
 
 
357 aa  173  5e-42  Geobacter sp. M21  Bacteria  n/a    hitchhiker  2.56416e-22 
 
 
-
 
NC_013173  Dbac_0491  response regulator receiver modulated metal dependent phosphohydrolase  45.6 
 
 
522 aa  172  6.999999999999999e-42  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.165576  n/a   
 
 
-
 
NC_007954  Sden_0663  response regulator receiver  36.08 
 
 
340 aa  172  6.999999999999999e-42  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0492  response regulator receiver modulated metal dependent phosphohydrolase  46.28 
 
 
508 aa  172  7.999999999999999e-42  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.0844408  n/a   
 
 
-
 
NC_009718  Fnod_1705  response regulator receiver modulated metal dependent phosphohydrolase  40.98 
 
 
471 aa  172  9e-42  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  n/a   
 
 
-
 
NC_007519  Dde_3114  metal dependent phosphohydrolase  47.57 
 
 
523 aa  172  9e-42  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  hitchhiker  0.00390297  n/a   
 
 
-
 
NC_009456  VC0395_1019  putative response regulator  45.45 
 
 
522 aa  172  9e-42  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_009943  Dole_1136  response regulator receiver modulated metal dependent phosphohydrolase  38.27 
 
 
348 aa  171  1e-41  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_003910  CPS_4164  response regulator/phosphatase  34.05 
 
 
352 aa  171  2e-41  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_010644  Emin_0051  metal dependent phosphohydrolase  44.04 
 
 
407 aa  171  2e-41  Elusimicrobium minutum Pei191  Bacteria  normal  normal 
 
 
-
 
NC_007954  Sden_2546  metal-dependent phosphohydrolase  43.22 
 
 
515 aa  171  2e-41  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_0737  metal dependent phosphohydrolase  44.93 
 
 
254 aa  170  3e-41  Delftia acidovorans SPH-1  Bacteria  normal  0.752336  normal 
 
 
-
 
NC_007575  Suden_1924  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  32.08 
 
 
367 aa  170  3e-41  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.620973  n/a   
 
 
-
 
NC_009616  Tmel_0497  response regulator receiver modulated metal dependent phosphohydrolase  41.36 
 
 
432 aa  168  1e-40  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_0961  metal dependent phosphohydrolase  45.54 
 
 
212 aa  167  2e-40  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_013216  Dtox_2814  putative PAS/PAC sensor protein  41.71 
 
 
1335 aa  167  2.9999999999999998e-40  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal  0.988399 
 
 
-
 
NC_008345  Sfri_2755  response regulator receiver modulated metal dependent phosphohydrolase  41.54 
 
 
520 aa  167  2.9999999999999998e-40  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_1546  response regulator receiver modulated metal dependent phosphohydrolase  35.28 
 
 
368 aa  167  2.9999999999999998e-40  Geobacter lovleyi SZ  Bacteria  normal  0.61009  n/a   
 
 
-
 
NC_010424  Daud_1728  putative PAS/PAC sensor protein  44.9 
 
 
1171 aa  167  4e-40  Candidatus Desulforudis audaxviator MP104C  Bacteria  hitchhiker  0.00367624  n/a   
 
 
-
 
NC_009718  Fnod_1101  response regulator receiver modulated metal dependent phosphohydrolase  41.05 
 
 
450 aa  166  5e-40  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  n/a   
 
 
-
 
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