More than 300 homologs were found in PanDaTox collection
for query gene M446_0838 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010511  M446_0838  response regulator receiver modulated metal dependent phosphohydrolase  100 
 
 
378 aa  759    Methylobacterium sp. 4-46  Bacteria  normal  0.8404  normal 
 
 
-
 
NC_010172  Mext_0206  metal-dependent phosphohydrolase  66.85 
 
 
369 aa  493  9.999999999999999e-139  Methylobacterium extorquens PA1  Bacteria  normal  0.44114  normal  0.760724 
 
 
-
 
NC_011757  Mchl_0150  response regulator receiver modulated metal dependent phosphohydrolase  66.85 
 
 
369 aa  493  9.999999999999999e-139  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.245203 
 
 
-
 
NC_010505  Mrad2831_1613  response regulator receiver modulated metal dependent phosphohydrolase  66.58 
 
 
487 aa  487  1e-136  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.350204  hitchhiker  0.000130728 
 
 
-
 
NC_011004  Rpal_0148  response regulator receiver modulated metal dependent phosphohydrolase  55.56 
 
 
385 aa  370  1e-101  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.750781  n/a   
 
 
-
 
NC_011989  Avi_0523  Response regulator protein  48.08 
 
 
359 aa  310  2e-83  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_012850  Rleg_3169  response regulator receiver modulated metal dependent phosphohydrolase  48.71 
 
 
353 aa  303  4.0000000000000003e-81  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.821118  normal 
 
 
-
 
NC_010725  Mpop_3894  response regulator receiver modulated metal dependent phosphohydrolase  51.63 
 
 
353 aa  297  2e-79  Methylobacterium populi BJ001  Bacteria  normal  0.0109719  normal  0.416002 
 
 
-
 
NC_010172  Mext_3509  metal-dependent phosphohydrolase  52.67 
 
 
351 aa  294  2e-78  Methylobacterium extorquens PA1  Bacteria  normal  0.305053  normal 
 
 
-
 
NC_010511  M446_5359  response regulator receiver modulated metal dependent phosphohydrolase  48.65 
 
 
347 aa  292  5e-78  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.0670454 
 
 
-
 
NC_011757  Mchl_3816  response regulator receiver modulated metal dependent phosphohydrolase  52.33 
 
 
351 aa  291  1e-77  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.0960158  normal 
 
 
-
 
NC_011757  Mchl_0538  response regulator receiver modulated metal dependent phosphohydrolase  52.33 
 
 
363 aa  291  2e-77  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.973232  normal 
 
 
-
 
NC_011989  Avi_4319  Metal dependent phosphohydrolase with a response regulator receiver protein  47.94 
 
 
382 aa  289  4e-77  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_1183  response regulator receiver modulated metal dependent phosphohydrolase  44.51 
 
 
363 aa  285  7e-76  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_2085  response regulator receiver modulated metal dependent phosphohydrolase  47.62 
 
 
345 aa  280  3e-74  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.931733  normal  0.012958 
 
 
-
 
NC_007298  Daro_2902  response regulator receiver  44.28 
 
 
350 aa  276  5e-73  Dechloromonas aromatica RCB  Bacteria  normal  0.1984  normal  0.246098 
 
 
-
 
NC_011901  Tgr7_0081  two component transcriptional regulator, AraC family  45.22 
 
 
399 aa  275  1.0000000000000001e-72  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_007404  Tbd_2670  metal dependent phosphohydrolase, HD region  46.5 
 
 
344 aa  270  2e-71  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_1828  response regulator receiver modulated metal dependent phosphohydrolase  41.76 
 
 
379 aa  265  1e-69  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.723665 
 
 
-
 
NC_010717  PXO_00070  Two-component system response regulator RpfG  42.73 
 
 
353 aa  259  4e-68  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.0844737  n/a   
 
 
-
 
NC_007947  Mfla_2655  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  43.52 
 
 
353 aa  259  5.0000000000000005e-68  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_010577  XfasM23_0399  response regulator receiver modulated metal dependent phosphohydrolase  40.71 
 
 
384 aa  250  2e-65  Xylella fastidiosa M23  Bacteria  normal  n/a   
 
 
-
 
NC_010513  Xfasm12_0458  response regulator receiver protein  40.71 
 
 
384 aa  250  2e-65  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_011894  Mnod_5340  response regulator receiver modulated metal dependent phosphohydrolase  45.68 
 
 
348 aa  249  8e-65  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.64097  n/a   
 
 
-
 
NC_008577  Shewana3_3418  response regulator receiver modulated metal dependent phosphohydrolase  40.63 
 
 
338 aa  246  6e-64  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_008321  Shewmr4_0716  response regulator receiver modulated metal dependent phosphohydrolase  40.32 
 
 
338 aa  245  8e-64  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3306  response regulator receiver modulated metal dependent phosphohydrolase  40.32 
 
 
338 aa  245  8e-64  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_3408  response regulator receiver modulated metal dependent phosphohydrolase  43.46 
 
 
346 aa  244  9.999999999999999e-64  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_009438  Sputcn32_3141  response regulator receiver modulated metal dependent phosphohydrolase  40.63 
 
 
338 aa  243  3.9999999999999997e-63  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_0860  response regulator  39.68 
 
 
339 aa  241  1e-62  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_009665  Shew185_0836  response regulator receiver modulated metal dependent phosphohydrolase  41.64 
 
 
338 aa  241  2e-62  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_010681  Bphyt_0187  response regulator receiver modulated metal dependent phosphohydrolase  40 
 
 
354 aa  241  2e-62  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.0125166 
 
 
-
 
NC_009052  Sbal_3504  response regulator receiver modulated metal dependent phosphohydrolase  41.64 
 
 
338 aa  241  2e-62  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_0859  response regulator receiver modulated metal dependent phosphohydrolase  41.64 
 
 
338 aa  241  2e-62  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3549  response regulator receiver modulated metal dependent phosphohydrolase  41.64 
 
 
348 aa  238  1e-61  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_5034  response regulator receiver modulated metal dependent phosphohydrolase  43.83 
 
 
348 aa  238  2e-61  Methylobacterium sp. 4-46  Bacteria  normal  0.749308  hitchhiker  0.00297277 
 
 
-
 
NC_008321  Shewmr4_0481  response regulator receiver modulated metal dependent phosphohydrolase  41.64 
 
 
348 aa  238  2e-61  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_003910  CPS_4164  response regulator/phosphatase  40.66 
 
 
352 aa  237  3e-61  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_0871  response regulator receiver modulated metal dependent phosphohydrolase  41.31 
 
 
338 aa  237  3e-61  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_008321  Shewmr4_0792  response regulator receiver modulated metal dependent phosphohydrolase  38.44 
 
 
331 aa  236  5.0000000000000005e-61  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3231  response regulator receiver modulated metal dependent phosphohydrolase  38.44 
 
 
331 aa  236  5.0000000000000005e-61  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_2951  response regulator receiver protein  40 
 
 
340 aa  236  7e-61  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.129077 
 
 
-
 
NC_012560  Avin_25160  response regulator  40.06 
 
 
356 aa  235  1.0000000000000001e-60  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_008740  Maqu_3676  response regulator receiver modulated metal dependent phosphohydrolase  40.91 
 
 
328 aa  234  1.0000000000000001e-60  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_4003  response regulator  39.51 
 
 
357 aa  234  2.0000000000000002e-60  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_007575  Suden_1924  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  37.28 
 
 
367 aa  234  2.0000000000000002e-60  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.620973  n/a   
 
 
-
 
NC_010506  Swoo_3313  response regulator receiver modulated metal dependent phosphohydrolase  39.39 
 
 
343 aa  234  2.0000000000000002e-60  Shewanella woodyi ATCC 51908  Bacteria  normal  hitchhiker  0.00000482447 
 
 
-
 
NC_009901  Spea_0629  response regulator receiver modulated metal dependent phosphohydrolase  38.66 
 
 
339 aa  234  2.0000000000000002e-60  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_008228  Patl_2248  response regulator receiver modulated metal dependent phosphohydrolase  40.8 
 
 
331 aa  233  3e-60  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_3523  response regulator receiver modulated metal dependent phosphohydrolase  39.36 
 
 
363 aa  234  3e-60  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_6015  response regulator receiver modulated metal dependent phosphohydrolase  40.8 
 
 
333 aa  233  5e-60  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_009092  Shew_3199  response regulator receiver modulated metal dependent phosphohydrolase  40.33 
 
 
339 aa  231  1e-59  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_3553  response regulator receiver  37.71 
 
 
384 aa  230  2e-59  Dechloromonas aromatica RCB  Bacteria  normal  0.739627  normal 
 
 
-
 
NC_008577  Shewana3_3334  response regulator receiver modulated metal dependent phosphohydrolase  38.44 
 
 
331 aa  231  2e-59  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_0479  response regulator receiver modulated metal dependent phosphohydrolase  40.98 
 
 
350 aa  230  3e-59  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_3165  response regulator receiver modulated metal dependent phosphohydrolase  40.45 
 
 
367 aa  229  6e-59  Magnetococcus sp. MC-1  Bacteria  normal  0.0569095  normal  0.0154692 
 
 
-
 
NC_007954  Sden_3723  response regulator receiver  37.46 
 
 
338 aa  229  8e-59  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_2505  response regulator receiver modulated metal dependent phosphohydrolase  41.28 
 
 
331 aa  227  3e-58  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_4196  response regulator receiver modulated metal dependent phosphohydrolase  36.12 
 
 
350 aa  226  6e-58  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_012560  Avin_50640  response regulator with metal dependent phosphohydrolase activity (two-component)  42.76 
 
 
347 aa  225  1e-57  Azotobacter vinelandii DJ  Bacteria  normal  0.121542  n/a   
 
 
-
 
NC_013173  Dbac_2017  response regulator receiver modulated metal dependent phosphohydrolase  35.67 
 
 
379 aa  225  1e-57  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.98115  n/a   
 
 
-
 
NC_009654  Mmwyl1_1086  response regulator receiver modulated metal dependent phosphohydrolase  38.34 
 
 
331 aa  223  4e-57  Marinomonas sp. MWYL1  Bacteria  normal  0.226857  hitchhiker  0.0000000112469 
 
 
-
 
NC_007298  Daro_0007  response regulator receiver modulated metal dependent phosphohydrolase  38.87 
 
 
379 aa  222  8e-57  Dechloromonas aromatica RCB  Bacteria  normal  0.829613  normal  0.0284762 
 
 
-
 
NC_010506  Swoo_2978  response regulator receiver modulated metal dependent phosphohydrolase  35.88 
 
 
369 aa  222  8e-57  Shewanella woodyi ATCC 51908  Bacteria  normal  normal  0.806511 
 
 
-
 
NC_009654  Mmwyl1_0356  response regulator receiver modulated metal dependent phosphohydrolase  38.53 
 
 
360 aa  221  1.9999999999999999e-56  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_3111  response regulator receiver protein  38.44 
 
 
328 aa  221  1.9999999999999999e-56  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.0637882 
 
 
-
 
NC_011769  DvMF_1097  response regulator receiver modulated metal dependent phosphohydrolase  38.98 
 
 
391 aa  219  3.9999999999999997e-56  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.151318 
 
 
-
 
NC_009831  Ssed_3915  response regulator receiver modulated metal dependent phosphohydrolase  34.29 
 
 
356 aa  219  5e-56  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_009457  VC0395_A0963  response regulator  36.92 
 
 
441 aa  218  1e-55  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_010506  Swoo_3823  response regulator receiver modulated metal dependent phosphohydrolase  35.55 
 
 
354 aa  217  2e-55  Shewanella woodyi ATCC 51908  Bacteria  normal  normal 
 
 
-
 
NC_007519  Dde_1942  metal dependent phosphohydrolase  38.81 
 
 
363 aa  218  2e-55  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.284574  n/a   
 
 
-
 
NC_007348  Reut_B4068  response regulator receiver  39.55 
 
 
377 aa  216  4e-55  Ralstonia eutropha JMP134  Bacteria  normal  0.706307  n/a   
 
 
-
 
NC_007298  Daro_3458  response regulator receiver  37.75 
 
 
365 aa  215  9e-55  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_2833  response regulator receiver modulated metal dependent phosphohydrolase  39.67 
 
 
360 aa  215  9e-55  Thauera sp. MZ1T  Bacteria  normal  0.809465  n/a   
 
 
-
 
NC_013173  Dbac_2325  response regulator receiver modulated metal dependent phosphohydrolase  38.46 
 
 
362 aa  215  9.999999999999999e-55  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.663275  n/a   
 
 
-
 
NC_007954  Sden_0663  response regulator receiver  36.52 
 
 
340 aa  214  1.9999999999999998e-54  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_01756  Response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase)  33.72 
 
 
337 aa  212  7e-54  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.844049  n/a   
 
 
-
 
NC_008752  Aave_2064  response regulator receiver modulated metal dependent phosphohydrolase  37.46 
 
 
395 aa  212  7e-54  Acidovorax citrulli AAC00-1  Bacteria  normal  0.18463  normal  0.544249 
 
 
-
 
NC_010725  Mpop_4963  response regulator receiver modulated metal dependent phosphohydrolase  42.27 
 
 
350 aa  211  1e-53  Methylobacterium populi BJ001  Bacteria  normal  0.102256  normal  0.0892849 
 
 
-
 
NC_010524  Lcho_2452  response regulator receiver modulated metal dependent phosphohydrolase  40.75 
 
 
377 aa  211  2e-53  Leptothrix cholodnii SP-6  Bacteria  n/a    hitchhiker  0.00101758 
 
 
-
 
NC_011138  MADE_03429  two-component system response regulator (hybrid family) protein  38.25 
 
 
358 aa  211  2e-53  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_013522  Taci_1744  response regulator receiver modulated metal dependent phosphohydrolase  37.06 
 
 
373 aa  210  3e-53  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2574  response regulator  42.66 
 
 
368 aa  210  3e-53  Geobacter sulfurreducens PCA  Bacteria  normal  0.482084  n/a   
 
 
-
 
NC_013552  DhcVS_1406  response regulator  36.44 
 
 
351 aa  209  8e-53  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_1546  response regulator receiver modulated metal dependent phosphohydrolase  39.2 
 
 
368 aa  208  1e-52  Geobacter lovleyi SZ  Bacteria  normal  0.61009  n/a   
 
 
-
 
NC_013522  Taci_1373  response regulator receiver modulated metal dependent phosphohydrolase  35.55 
 
 
365 aa  208  1e-52  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_013946  Mrub_2733  response regulator receiver modulated metal dependent phosphohydrolase  40.06 
 
 
346 aa  207  2e-52  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_008741  Dvul_3024  response regulator receiver modulated metal dependent phosphohydrolase  37.91 
 
 
363 aa  207  2e-52  Desulfovibrio vulgaris DP4  Bacteria  normal  0.433593  n/a   
 
 
-
 
NC_010172  Mext_4449  metal-dependent phosphohydrolase  41.99 
 
 
358 aa  207  2e-52  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.508967 
 
 
-
 
NC_011757  Mchl_4913  response regulator receiver modulated metal dependent phosphohydrolase  45.2 
 
 
354 aa  207  3e-52  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.478904  normal  0.760596 
 
 
-
 
NC_014148  Plim_0679  response regulator receiver  38.95 
 
 
337 aa  206  7e-52  Planctomyces limnophilus DSM 3776  Bacteria  normal  0.0836964  n/a   
 
 
-
 
NC_009943  Dole_1136  response regulator receiver modulated metal dependent phosphohydrolase  34.65 
 
 
348 aa  205  1e-51  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_009654  Mmwyl1_2382  response regulator receiver modulated metal dependent phosphohydrolase  37.97 
 
 
359 aa  204  2e-51  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_010524  Lcho_1463  response regulator receiver modulated metal dependent phosphohydrolase  40 
 
 
364 aa  204  2e-51  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.404054 
 
 
-
 
NC_011992  Dtpsy_0962  response regulator receiver modulated metal dependent phosphohydrolase  37.26 
 
 
377 aa  204  2e-51  Acidovorax ebreus TPSY  Bacteria  normal  0.115091  n/a   
 
 
-
 
NC_008009  Acid345_4060  response regulator receiver modulated metal dependent phosphohydrolase  37.5 
 
 
365 aa  204  3e-51  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal  0.0748941 
 
 
-
 
NC_013223  Dret_2370  response regulator receiver modulated metal dependent phosphohydrolase  37.71 
 
 
370 aa  203  3e-51  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_3046  response regulator receiver modulated metal dependent phosphohydrolase  36.19 
 
 
365 aa  203  4e-51  Pelobacter propionicus DSM 2379  Bacteria  normal  0.0429754  n/a   
 
 
-
 
NC_011769  DvMF_2545  metal dependent phosphohydrolase  53.33 
 
 
269 aa  202  6e-51  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_008782  Ajs_1044  response regulator receiver modulated metal dependent phosphohydrolase  38.1 
 
 
377 aa  202  9e-51  Acidovorax sp. JS42  Bacteria  normal  normal  0.0516082 
 
 
-
 
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