More than 300 homologs were found in PanDaTox collection
for query gene Tcur_0595 on replicon NC_013510
Organism: Thermomonospora curvata DSM 43183



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013510  Tcur_0595  putative two component transcriptional regulator, winged helix family  100 
 
 
237 aa  468  1.0000000000000001e-131  Thermomonospora curvata DSM 43183  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_0895  response regulator receiver protein  83.47 
 
 
237 aa  396  1e-109  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_0453  putative winged helix family two component transcriptional regulator  83.19 
 
 
251 aa  395  1e-109  Thermobispora bispora DSM 43833  Bacteria  normal  0.190844  normal  0.275136 
 
 
-
 
NC_013131  Caci_8253  putative two component transcriptional regulator, winged helix family  80.93 
 
 
264 aa  352  2.9999999999999997e-96  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_007333  Tfu_2737  transcriptional regulatory protein  78.7 
 
 
253 aa  351  5e-96  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4376  putative two component transcriptional regulator, winged helix family  76.09 
 
 
255 aa  348  4e-95  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_008578  Acel_2025  response regulator receiver protein  77.78 
 
 
261 aa  343  1e-93  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_007777  Francci3_0443  response regulator receiver protein  70.28 
 
 
250 aa  333  1e-90  Frankia sp. CcI3  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_6176  winged helix family two component response transcriptional regulator  76.02 
 
 
247 aa  331  7.000000000000001e-90  Frankia sp. EAN1pec  Bacteria  normal  normal  0.186762 
 
 
-
 
NC_009664  Krad_0879  putative two component transcriptional regulator, winged helix family  73.68 
 
 
259 aa  328  4e-89  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.249855  hitchhiker  0.00478466 
 
 
-
 
NC_014151  Cfla_3090  putative two component transcriptional regulator, winged helix family  68.64 
 
 
241 aa  314  9e-85  Cellulomonas flavigena DSM 20109  Bacteria  normal  hitchhiker  0.0000121276 
 
 
-
 
NC_013521  Sked_04930  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  72.07 
 
 
249 aa  311  3.9999999999999997e-84  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.793732  normal 
 
 
-
 
NC_013530  Xcel_3035  putative two component transcriptional regulator, winged helix family  72.07 
 
 
243 aa  308  4e-83  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_0439  putative two component transcriptional regulator, winged helix family  65.27 
 
 
248 aa  305  3e-82  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.190602 
 
 
-
 
NC_012669  Bcav_3419  putative two component transcriptional regulator, winged helix family  67.52 
 
 
240 aa  303  2.0000000000000002e-81  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_4240  transcriptional regulator domain-containing protein  65.35 
 
 
257 aa  298  5e-80  Nocardioides sp. JS614  Bacteria  normal  0.466466  n/a   
 
 
-
 
NC_008541  Arth_3012  response regulator receiver protein  64.07 
 
 
232 aa  296  2e-79  Arthrobacter sp. FB24  Bacteria  normal  0.721979  n/a   
 
 
-
 
NC_011886  Achl_2724  putative two component transcriptional regulator, winged helix family  65.45 
 
 
232 aa  294  9e-79  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00387379 
 
 
-
 
NC_008146  Mmcs_4525  response regulator receiver protein  68.81 
 
 
257 aa  289  3e-77  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_4612  response regulator receiver protein  68.81 
 
 
257 aa  289  3e-77  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_009077  Mjls_4908  response regulator receiver protein  68.81 
 
 
257 aa  289  3e-77  Mycobacterium sp. JLS  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_5097  response regulator receiver protein  67.89 
 
 
267 aa  287  1e-76  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_6823  putative two component transcriptional regulator, winged helix family  67.41 
 
 
250 aa  286  2e-76  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_4646  putative two component transcriptional regulator, winged helix family  66.82 
 
 
249 aa  286  2e-76  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_009338  Mflv_1650  response regulator receiver protein  69.08 
 
 
278 aa  286  2e-76  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.0110992  normal 
 
 
-
 
NC_009565  TBFG_10833  transcriptional regulatory protein  69.08 
 
 
255 aa  284  1.0000000000000001e-75  Mycobacterium tuberculosis F11  Bacteria  normal  hitchhiker  0.00597919 
 
 
-
 
NC_009953  Sare_0337  winged helix family two component response transcriptional regulator  65.91 
 
 
239 aa  282  3.0000000000000004e-75  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.0279779 
 
 
-
 
NC_009380  Strop_0293  winged helix family two component response transcriptional regulator  66.51 
 
 
239 aa  282  3.0000000000000004e-75  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_014158  Tpau_3545  putative two component transcriptional regulator, winged helix family  66.67 
 
 
243 aa  275  7e-73  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.61486  n/a   
 
 
-
 
NC_013159  Svir_37670  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  63.36 
 
 
256 aa  273  2.0000000000000002e-72  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal  0.0528352 
 
 
-
 
NC_013947  Snas_6372  putative two component transcriptional regulator, winged helix family  61.74 
 
 
236 aa  271  8.000000000000001e-72  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_013235  Namu_4983  putative two component transcriptional regulator, winged helix family  63.96 
 
 
232 aa  270  1e-71  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_010816  BLD_1194  putative response regulator  57.02 
 
 
266 aa  266  2e-70  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_3935  transcriptional regulator domain protein  64.41 
 
 
270 aa  266  2.9999999999999995e-70  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_013721  HMPREF0424_0189  transcriptional regulatory protein, C-terminal domain protein  52.23 
 
 
296 aa  253  1.0000000000000001e-66  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_009565  TBFG_12898  transcriptional regulator  47.53 
 
 
252 aa  156  3e-37  Mycobacterium tuberculosis F11  Bacteria  normal  0.385025  normal 
 
 
-
 
NC_013169  Ksed_03550  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  48.06 
 
 
261 aa  154  8e-37  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.329191  normal 
 
 
-
 
NC_013440  Hoch_6843  putative two component transcriptional regulator, winged helix family  47.89 
 
 
258 aa  152  5e-36  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_002936  DET1126  transcriptional regulator  52.21 
 
 
223 aa  133  1.9999999999999998e-30  Dehalococcoides ethenogenes 195  Bacteria  decreased coverage  0.0000289398  n/a   
 
 
-
 
NC_013124  Afer_0241  putative two component transcriptional regulator, winged helix family  54.26 
 
 
217 aa  132  5e-30  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_013552  DhcVS_944  transcriptional regulator  51.47 
 
 
223 aa  132  6e-30  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_002936  DET1162  transcriptional regulator, putative  44 
 
 
238 aa  130  2.0000000000000002e-29  Dehalococcoides ethenogenes 195  Bacteria  normal  0.829609  n/a   
 
 
-
 
NC_009455  DehaBAV1_0955  two component transcriptional regulator  50 
 
 
223 aa  127  2.0000000000000002e-28  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  38.46 
 
 
226 aa  123  3e-27  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  36.73 
 
 
223 aa  119  3.9999999999999996e-26  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  40.1 
 
 
229 aa  119  4.9999999999999996e-26  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  36.92 
 
 
223 aa  119  6e-26  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  36.92 
 
 
223 aa  118  7e-26  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  36.92 
 
 
223 aa  118  7e-26  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  36.22 
 
 
223 aa  118  9e-26  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  36.22 
 
 
223 aa  118  9e-26  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  36.92 
 
 
223 aa  117  9.999999999999999e-26  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_005957  BT9727_1191  response regulator  36.41 
 
 
223 aa  117  9.999999999999999e-26  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  36.92 
 
 
223 aa  117  9.999999999999999e-26  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  36.36 
 
 
223 aa  117  9.999999999999999e-26  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  37.91 
 
 
236 aa  118  9.999999999999999e-26  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  36.92 
 
 
223 aa  118  9.999999999999999e-26  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  35.38 
 
 
223 aa  117  1.9999999999999998e-25  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  35.87 
 
 
228 aa  117  1.9999999999999998e-25  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_013165  Shel_19870  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  41.71 
 
 
224 aa  116  3.9999999999999997e-25  Slackia heliotrinireducens DSM 20476  Bacteria  normal  0.931606  normal 
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  36.52 
 
 
228 aa  115  5e-25  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_012034  Athe_0080  two component transcriptional regulator, winged helix family  36.96 
 
 
230 aa  115  5e-25  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  38.8 
 
 
232 aa  115  6.9999999999999995e-25  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  40.61 
 
 
234 aa  114  8.999999999999998e-25  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_013170  Ccur_08240  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  49.21 
 
 
236 aa  114  1.0000000000000001e-24  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.956318  normal  0.778898 
 
 
-
 
NC_007604  Synpcc7942_2305  two component transcriptional regulator  39.04 
 
 
228 aa  114  2.0000000000000002e-24  Synechococcus elongatus PCC 7942  Bacteria  normal  normal  0.79647 
 
 
-
 
NC_011830  Dhaf_0940  two component transcriptional regulator, winged helix family  38 
 
 
237 aa  112  4.0000000000000004e-24  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.324642  n/a   
 
 
-
 
NC_011830  Dhaf_1756  two component transcriptional regulator, winged helix family  36.87 
 
 
230 aa  112  6e-24  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.769657  n/a   
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  36.41 
 
 
227 aa  110  1.0000000000000001e-23  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_009767  Rcas_2782  two component transcriptional regulator  37.89 
 
 
231 aa  111  1.0000000000000001e-23  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.92379  normal 
 
 
-
 
NC_013411  GYMC61_3538  two component transcriptional regulator, winged helix family  37.31 
 
 
237 aa  110  1.0000000000000001e-23  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013093  Amir_3871  two component transcriptional regulator, winged helix family  39.91 
 
 
227 aa  111  1.0000000000000001e-23  Actinosynnema mirum DSM 43827  Bacteria  hitchhiker  0.0000000473157  n/a   
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  36.32 
 
 
232 aa  110  1.0000000000000001e-23  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_013204  Elen_2015  putative two component transcriptional regulator, winged helix family  40 
 
 
224 aa  110  2.0000000000000002e-23  Eggerthella lenta DSM 2243  Bacteria  normal  0.0839248  hitchhiker  0.0000000000000188648 
 
 
-
 
NC_008228  Patl_0218  two component transcriptional regulator  35.83 
 
 
239 aa  110  2.0000000000000002e-23  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_008262  CPR_2497  DNA-binding response regulator  35.78 
 
 
228 aa  110  2.0000000000000002e-23  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  37.43 
 
 
235 aa  110  2.0000000000000002e-23  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  38.42 
 
 
239 aa  110  2.0000000000000002e-23  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_007413  Ava_1922  two component transcriptional regulator  40.85 
 
 
228 aa  109  3e-23  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_009513  Lreu_0019  two component transcriptional regulator  41.67 
 
 
235 aa  109  3e-23  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_0444  DNA-binding response regulator  39.04 
 
 
233 aa  110  3e-23  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  n/a   
 
 
-
 
NC_013501  Rmar_0993  two component transcriptional regulator, winged helix family  36.27 
 
 
237 aa  110  3e-23  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_2242  two component transcriptional regulator, winged helix family  33.84 
 
 
224 aa  108  6e-23  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.415885 
 
 
-
 
NC_010718  Nther_1220  two component transcriptional regulator, winged helix family  43.94 
 
 
233 aa  108  7.000000000000001e-23  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  hitchhiker  0.00991602 
 
 
-
 
NC_011898  Ccel_1658  two component transcriptional regulator, winged helix family  36.9 
 
 
230 aa  108  7.000000000000001e-23  Clostridium cellulolyticum H10  Bacteria  normal  0.515101  n/a   
 
 
-
 
NC_012793  GWCH70_3409  two component transcriptional regulator, winged helix family  38.02 
 
 
236 aa  108  7.000000000000001e-23  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_0154  two component transcriptional regulator  31.89 
 
 
238 aa  108  7.000000000000001e-23  Clostridium phytofermentans ISDg  Bacteria  normal  0.644268  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  35.38 
 
 
239 aa  108  8.000000000000001e-23  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_009092  Shew_3419  two component transcriptional regulator  39.52 
 
 
242 aa  108  8.000000000000001e-23  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  35.38 
 
 
239 aa  108  8.000000000000001e-23  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_008261  CPF_2811  DNA-binding response regulator  41.03 
 
 
228 aa  108  9.000000000000001e-23  Clostridium perfringens ATCC 13124  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_3085  two component transcriptional regulator, winged helix family  39.39 
 
 
232 aa  108  9.000000000000001e-23  Desulfotomaculum acetoxidans DSM 771  Bacteria  unclonable  0.00000000315463  hitchhiker  0.000599707 
 
 
-
 
NC_002976  SERP2534  DNA-binding response regulator YycF  36.36 
 
 
233 aa  107  1e-22  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  38.62 
 
 
231 aa  108  1e-22  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_2570  two component transcriptional regulator, winged helix family  36.7 
 
 
239 aa  108  1e-22  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_008531  LEUM_1950  DNA-binding response regulator  37.37 
 
 
235 aa  107  1e-22  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.100456  n/a   
 
 
-
 
NC_011831  Cagg_3302  two component transcriptional regulator, winged helix family  38.55 
 
 
231 aa  107  1e-22  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.000343135 
 
 
-
 
NC_009253  Dred_1903  two component transcriptional regulator  37.95 
 
 
230 aa  108  1e-22  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_009616  Tmel_1838  two component transcriptional regulator  40.4 
 
 
239 aa  107  1e-22  Thermosipho melanesiensis BI429  Bacteria  hitchhiker  0.00000194698  n/a   
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  37.78 
 
 
237 aa  108  1e-22  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
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