More than 300 homologs were found in PanDaTox collection
for query gene Tpau_3545 on replicon NC_014158
Organism: Tsukamurella paurometabola DSM 20162



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014158  Tpau_3545  putative two component transcriptional regulator, winged helix family  100 
 
 
243 aa  476  1e-133  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.61486  n/a   
 
 
-
 
NC_008146  Mmcs_4525  response regulator receiver protein  79.65 
 
 
257 aa  354  7.999999999999999e-97  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_4612  response regulator receiver protein  79.65 
 
 
257 aa  354  7.999999999999999e-97  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_009077  Mjls_4908  response regulator receiver protein  79.65 
 
 
257 aa  354  7.999999999999999e-97  Mycobacterium sp. JLS  Bacteria  normal  normal 
 
 
-
 
NC_013441  Gbro_3935  transcriptional regulator domain protein  76.62 
 
 
270 aa  345  3e-94  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_009338  Mflv_1650  response regulator receiver protein  78.64 
 
 
278 aa  342  2.9999999999999997e-93  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.0110992  normal 
 
 
-
 
NC_008726  Mvan_5097  response regulator receiver protein  78.18 
 
 
267 aa  338  5.9999999999999996e-92  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_6823  putative two component transcriptional regulator, winged helix family  73.21 
 
 
250 aa  327  1.0000000000000001e-88  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009565  TBFG_10833  transcriptional regulatory protein  76.74 
 
 
255 aa  321  5e-87  Mycobacterium tuberculosis F11  Bacteria  normal  hitchhiker  0.00597919 
 
 
-
 
NC_013235  Namu_4983  putative two component transcriptional regulator, winged helix family  63.11 
 
 
232 aa  278  7e-74  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_013159  Svir_37670  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  61.3 
 
 
256 aa  276  1e-73  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal  0.0528352 
 
 
-
 
NC_013595  Sros_0895  response regulator receiver protein  60.83 
 
 
237 aa  276  2e-73  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013510  Tcur_0595  putative two component transcriptional regulator, winged helix family  66.36 
 
 
237 aa  275  6e-73  Thermomonospora curvata DSM 43183  Bacteria  normal  n/a   
 
 
-
 
NC_014165  Tbis_0453  putative winged helix family two component transcriptional regulator  58.33 
 
 
251 aa  267  1e-70  Thermobispora bispora DSM 43833  Bacteria  normal  0.190844  normal  0.275136 
 
 
-
 
NC_009664  Krad_0879  putative two component transcriptional regulator, winged helix family  63.48 
 
 
259 aa  265  7e-70  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.249855  hitchhiker  0.00478466 
 
 
-
 
NC_007333  Tfu_2737  transcriptional regulatory protein  62.82 
 
 
253 aa  263  1e-69  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_007777  Francci3_0443  response regulator receiver protein  61.99 
 
 
250 aa  262  3e-69  Frankia sp. CcI3  Bacteria  normal  normal 
 
 
-
 
NC_008578  Acel_2025  response regulator receiver protein  62.07 
 
 
261 aa  263  3e-69  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_6176  winged helix family two component response transcriptional regulator  61.99 
 
 
247 aa  262  4e-69  Frankia sp. EAN1pec  Bacteria  normal  normal  0.186762 
 
 
-
 
NC_013757  Gobs_4646  putative two component transcriptional regulator, winged helix family  62.67 
 
 
249 aa  261  6.999999999999999e-69  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_013131  Caci_8253  putative two component transcriptional regulator, winged helix family  65.07 
 
 
264 aa  260  1e-68  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_3419  putative two component transcriptional regulator, winged helix family  64.25 
 
 
240 aa  259  2e-68  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_013174  Jden_0439  putative two component transcriptional regulator, winged helix family  57.02 
 
 
248 aa  258  4e-68  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.190602 
 
 
-
 
NC_014210  Ndas_4376  putative two component transcriptional regulator, winged helix family  61.5 
 
 
255 aa  258  5.0000000000000005e-68  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_009953  Sare_0337  winged helix family two component response transcriptional regulator  60.71 
 
 
239 aa  256  3e-67  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.0279779 
 
 
-
 
NC_014151  Cfla_3090  putative two component transcriptional regulator, winged helix family  59.15 
 
 
241 aa  255  5e-67  Cellulomonas flavigena DSM 20109  Bacteria  normal  hitchhiker  0.0000121276 
 
 
-
 
NC_009380  Strop_0293  winged helix family two component response transcriptional regulator  60.63 
 
 
239 aa  254  1.0000000000000001e-66  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_6372  putative two component transcriptional regulator, winged helix family  58.48 
 
 
236 aa  252  4.0000000000000004e-66  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_013530  Xcel_3035  putative two component transcriptional regulator, winged helix family  61.64 
 
 
243 aa  252  4.0000000000000004e-66  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_4240  transcriptional regulator domain-containing protein  57.58 
 
 
257 aa  250  1e-65  Nocardioides sp. JS614  Bacteria  normal  0.466466  n/a   
 
 
-
 
NC_013521  Sked_04930  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  60 
 
 
249 aa  247  1e-64  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.793732  normal 
 
 
-
 
NC_008541  Arth_3012  response regulator receiver protein  56.94 
 
 
232 aa  241  7.999999999999999e-63  Arthrobacter sp. FB24  Bacteria  normal  0.721979  n/a   
 
 
-
 
NC_011886  Achl_2724  putative two component transcriptional regulator, winged helix family  56.02 
 
 
232 aa  240  1e-62  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00387379 
 
 
-
 
NC_010816  BLD_1194  putative response regulator  51.27 
 
 
266 aa  231  7.000000000000001e-60  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_013721  HMPREF0424_0189  transcriptional regulatory protein, C-terminal domain protein  48.28 
 
 
296 aa  221  9e-57  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_009565  TBFG_12898  transcriptional regulator  47.35 
 
 
252 aa  155  4e-37  Mycobacterium tuberculosis F11  Bacteria  normal  0.385025  normal 
 
 
-
 
NC_013169  Ksed_03550  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  40.38 
 
 
261 aa  143  3e-33  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.329191  normal 
 
 
-
 
NC_013440  Hoch_6843  putative two component transcriptional regulator, winged helix family  44.44 
 
 
258 aa  137  2e-31  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_002936  DET1162  transcriptional regulator, putative  36.73 
 
 
238 aa  124  1e-27  Dehalococcoides ethenogenes 195  Bacteria  normal  0.829609  n/a   
 
 
-
 
NC_013124  Afer_0241  putative two component transcriptional regulator, winged helix family  51.56 
 
 
217 aa  122  4e-27  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_013170  Ccur_08240  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  47.62 
 
 
236 aa  118  9.999999999999999e-26  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.956318  normal  0.778898 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  37.16 
 
 
229 aa  115  3.9999999999999997e-25  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_013165  Shel_19870  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  43.33 
 
 
224 aa  115  5e-25  Slackia heliotrinireducens DSM 20476  Bacteria  normal  0.931606  normal 
 
 
-
 
NC_013552  DhcVS_944  transcriptional regulator  48.48 
 
 
223 aa  115  6e-25  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_002936  DET1126  transcriptional regulator  48.48 
 
 
223 aa  115  6.9999999999999995e-25  Dehalococcoides ethenogenes 195  Bacteria  decreased coverage  0.0000289398  n/a   
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  35.79 
 
 
223 aa  114  1.0000000000000001e-24  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  35.79 
 
 
223 aa  114  1.0000000000000001e-24  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  39.88 
 
 
228 aa  114  1.0000000000000001e-24  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  36.32 
 
 
223 aa  114  2.0000000000000002e-24  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  36.32 
 
 
223 aa  114  2.0000000000000002e-24  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  36.32 
 
 
223 aa  113  3e-24  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_005957  BT9727_1191  response regulator  35.79 
 
 
223 aa  113  3e-24  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  36.32 
 
 
223 aa  112  4.0000000000000004e-24  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  36.32 
 
 
223 aa  112  4.0000000000000004e-24  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  39.64 
 
 
232 aa  112  5e-24  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_0955  two component transcriptional regulator  47.73 
 
 
223 aa  112  5e-24  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_2286  two component transcriptional regulator, winged helix family  36.22 
 
 
231 aa  110  2.0000000000000002e-23  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000000000188753  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  38.83 
 
 
231 aa  110  2.0000000000000002e-23  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  35.79 
 
 
223 aa  110  3e-23  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  35.79 
 
 
223 aa  109  3e-23  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  37.77 
 
 
239 aa  109  4.0000000000000004e-23  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_013204  Elen_2015  putative two component transcriptional regulator, winged helix family  43.65 
 
 
224 aa  109  4.0000000000000004e-23  Eggerthella lenta DSM 2243  Bacteria  normal  0.0839248  hitchhiker  0.0000000000000188648 
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  35.71 
 
 
236 aa  108  7.000000000000001e-23  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  43.57 
 
 
235 aa  107  1e-22  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_010001  Cphy_3429  two component transcriptional regulator  34.51 
 
 
233 aa  107  1e-22  Clostridium phytofermentans ISDg  Bacteria  normal  0.0608192  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  42.96 
 
 
239 aa  108  1e-22  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  35.79 
 
 
223 aa  107  1e-22  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  38.04 
 
 
228 aa  108  1e-22  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  42.96 
 
 
239 aa  108  1e-22  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  44.44 
 
 
239 aa  107  2e-22  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_009523  RoseRS_4619  two component transcriptional regulator  39.23 
 
 
245 aa  107  2e-22  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.0926269 
 
 
-
 
NC_009718  Fnod_1490  two component transcriptional regulator  43.88 
 
 
239 aa  107  2e-22  Fervidobacterium nodosum Rt17-B1  Bacteria  unclonable  0.000000000120928  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  44.44 
 
 
239 aa  107  2e-22  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_009523  RoseRS_1397  two component transcriptional regulator  40.66 
 
 
261 aa  106  3e-22  Roseiflexus sp. RS-1  Bacteria  normal  0.0231814  hitchhiker  0.000111966 
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  36.26 
 
 
226 aa  106  3e-22  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_012918  GM21_1271  two component transcriptional regulator, winged helix family  39.66 
 
 
225 aa  106  4e-22  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_009513  Lreu_0019  two component transcriptional regulator  41.84 
 
 
235 aa  106  4e-22  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  39.88 
 
 
235 aa  106  4e-22  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_013169  Ksed_03700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  34.05 
 
 
226 aa  105  4e-22  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.132847 
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  35.76 
 
 
235 aa  106  4e-22  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_008262  CPR_2497  DNA-binding response regulator  44.96 
 
 
228 aa  105  5e-22  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  37.42 
 
 
223 aa  105  6e-22  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_008531  LEUM_1950  DNA-binding response regulator  36 
 
 
235 aa  105  6e-22  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.100456  n/a   
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  35.76 
 
 
235 aa  105  6e-22  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  42.55 
 
 
234 aa  105  6e-22  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_010003  Pmob_0875  two component transcriptional regulator  37.5 
 
 
242 aa  105  7e-22  Petrotoga mobilis SJ95  Bacteria  decreased coverage  0.000486966  n/a   
 
 
-
 
NC_009616  Tmel_1838  two component transcriptional regulator  41.84 
 
 
239 aa  105  7e-22  Thermosipho melanesiensis BI429  Bacteria  hitchhiker  0.00000194698  n/a   
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  34.88 
 
 
235 aa  105  7e-22  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_011146  Gbem_2952  two component transcriptional regulator, winged helix family  39.11 
 
 
225 aa  105  7e-22  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  35.76 
 
 
235 aa  105  8e-22  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  35.76 
 
 
235 aa  105  8e-22  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_009767  Rcas_0421  two component transcriptional regulator  38.67 
 
 
245 aa  105  8e-22  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.0518956  normal 
 
 
-
 
NC_005957  BT9727_5147  response regulator  35.76 
 
 
235 aa  105  8e-22  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_006274  BCZK5163  response regulator  35.76 
 
 
235 aa  105  8e-22  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  35.76 
 
 
235 aa  105  8e-22  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  35.76 
 
 
235 aa  105  8e-22  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  35.76 
 
 
235 aa  105  8e-22  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_008025  Dgeo_0130  two component transcriptional regulator  45.71 
 
 
229 aa  105  8e-22  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.848842  normal 
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  35.76 
 
 
235 aa  105  8e-22  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  41.55 
 
 
239 aa  104  1e-21  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
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