More than 300 homologs were found in PanDaTox collection
for query gene Amir_6823 on replicon NC_013093
Organism: Actinosynnema mirum DSM 43827



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013093  Amir_6823  putative two component transcriptional regulator, winged helix family  100 
 
 
250 aa  490  9.999999999999999e-139  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_008146  Mmcs_4525  response regulator receiver protein  75.97 
 
 
257 aa  338  4e-92  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_4612  response regulator receiver protein  75.97 
 
 
257 aa  338  4e-92  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_009077  Mjls_4908  response regulator receiver protein  75.97 
 
 
257 aa  338  4e-92  Mycobacterium sp. JLS  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_5097  response regulator receiver protein  76.71 
 
 
267 aa  331  7.000000000000001e-90  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_009338  Mflv_1650  response regulator receiver protein  75.33 
 
 
278 aa  329  2e-89  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.0110992  normal 
 
 
-
 
NC_014158  Tpau_3545  putative two component transcriptional regulator, winged helix family  73.21 
 
 
243 aa  326  2.0000000000000001e-88  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.61486  n/a   
 
 
-
 
NC_013441  Gbro_3935  transcriptional regulator domain protein  74.89 
 
 
270 aa  317  7.999999999999999e-86  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_009565  TBFG_10833  transcriptional regulatory protein  76.64 
 
 
255 aa  314  7e-85  Mycobacterium tuberculosis F11  Bacteria  normal  hitchhiker  0.00597919 
 
 
-
 
NC_013159  Svir_37670  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  66.67 
 
 
256 aa  299  2e-80  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal  0.0528352 
 
 
-
 
NC_013235  Namu_4983  putative two component transcriptional regulator, winged helix family  63.96 
 
 
232 aa  289  3e-77  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_013510  Tcur_0595  putative two component transcriptional regulator, winged helix family  67.41 
 
 
237 aa  286  2e-76  Thermomonospora curvata DSM 43183  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_4646  putative two component transcriptional regulator, winged helix family  61.13 
 
 
249 aa  282  3.0000000000000004e-75  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_014165  Tbis_0453  putative winged helix family two component transcriptional regulator  64.44 
 
 
251 aa  282  3.0000000000000004e-75  Thermobispora bispora DSM 43833  Bacteria  normal  0.190844  normal  0.275136 
 
 
-
 
NC_008578  Acel_2025  response regulator receiver protein  66.97 
 
 
261 aa  280  1e-74  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_009953  Sare_0337  winged helix family two component response transcriptional regulator  60.5 
 
 
239 aa  280  2e-74  Salinispora arenicola CNS-205  Bacteria  normal  normal  0.0279779 
 
 
-
 
NC_009380  Strop_0293  winged helix family two component response transcriptional regulator  60.08 
 
 
239 aa  278  5e-74  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_3419  putative two component transcriptional regulator, winged helix family  66.96 
 
 
240 aa  277  1e-73  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_007333  Tfu_2737  transcriptional regulatory protein  59.92 
 
 
253 aa  277  1e-73  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_009921  Franean1_6176  winged helix family two component response transcriptional regulator  65.78 
 
 
247 aa  277  1e-73  Frankia sp. EAN1pec  Bacteria  normal  normal  0.186762 
 
 
-
 
NC_007777  Francci3_0443  response regulator receiver protein  65.33 
 
 
250 aa  276  3e-73  Frankia sp. CcI3  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_0895  response regulator receiver protein  65.2 
 
 
237 aa  274  8e-73  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013174  Jden_0439  putative two component transcriptional regulator, winged helix family  61.28 
 
 
248 aa  273  3e-72  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.190602 
 
 
-
 
NC_013521  Sked_04930  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  65.33 
 
 
249 aa  271  6e-72  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.793732  normal 
 
 
-
 
NC_013131  Caci_8253  putative two component transcriptional regulator, winged helix family  66.19 
 
 
264 aa  271  8.000000000000001e-72  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_4376  putative two component transcriptional regulator, winged helix family  62.88 
 
 
255 aa  270  1e-71  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013947  Snas_6372  putative two component transcriptional regulator, winged helix family  59.64 
 
 
236 aa  269  2.9999999999999997e-71  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_009664  Krad_0879  putative two component transcriptional regulator, winged helix family  62.67 
 
 
259 aa  265  4e-70  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.249855  hitchhiker  0.00478466 
 
 
-
 
NC_008699  Noca_4240  transcriptional regulator domain-containing protein  62.56 
 
 
257 aa  262  4.999999999999999e-69  Nocardioides sp. JS614  Bacteria  normal  0.466466  n/a   
 
 
-
 
NC_013530  Xcel_3035  putative two component transcriptional regulator, winged helix family  62.72 
 
 
243 aa  261  8e-69  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_014151  Cfla_3090  putative two component transcriptional regulator, winged helix family  63.84 
 
 
241 aa  259  4e-68  Cellulomonas flavigena DSM 20109  Bacteria  normal  hitchhiker  0.0000121276 
 
 
-
 
NC_011886  Achl_2724  putative two component transcriptional regulator, winged helix family  58.9 
 
 
232 aa  254  9e-67  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00387379 
 
 
-
 
NC_008541  Arth_3012  response regulator receiver protein  56.84 
 
 
232 aa  252  4.0000000000000004e-66  Arthrobacter sp. FB24  Bacteria  normal  0.721979  n/a   
 
 
-
 
NC_010816  BLD_1194  putative response regulator  53.02 
 
 
266 aa  248  7e-65  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_013721  HMPREF0424_0189  transcriptional regulatory protein, C-terminal domain protein  48.05 
 
 
296 aa  233  2.0000000000000002e-60  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_009565  TBFG_12898  transcriptional regulator  49.78 
 
 
252 aa  169  4e-41  Mycobacterium tuberculosis F11  Bacteria  normal  0.385025  normal 
 
 
-
 
NC_013169  Ksed_03550  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  41.73 
 
 
261 aa  156  3e-37  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.329191  normal 
 
 
-
 
NC_013440  Hoch_6843  putative two component transcriptional regulator, winged helix family  47.57 
 
 
258 aa  142  6e-33  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_002936  DET1162  transcriptional regulator, putative  43.33 
 
 
238 aa  130  2.0000000000000002e-29  Dehalococcoides ethenogenes 195  Bacteria  normal  0.829609  n/a   
 
 
-
 
NC_013124  Afer_0241  putative two component transcriptional regulator, winged helix family  45.3 
 
 
217 aa  125  7e-28  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  36.96 
 
 
229 aa  120  1.9999999999999998e-26  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_013552  DhcVS_944  transcriptional regulator  45.38 
 
 
223 aa  119  7e-26  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_002936  DET1126  transcriptional regulator  49.15 
 
 
223 aa  117  9.999999999999999e-26  Dehalococcoides ethenogenes 195  Bacteria  decreased coverage  0.0000289398  n/a   
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  36.51 
 
 
223 aa  117  1.9999999999999998e-25  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  36.51 
 
 
223 aa  117  1.9999999999999998e-25  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_013165  Shel_19870  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  36.28 
 
 
224 aa  117  1.9999999999999998e-25  Slackia heliotrinireducens DSM 20476  Bacteria  normal  0.931606  normal 
 
 
-
 
NC_008531  LEUM_1950  DNA-binding response regulator  38.83 
 
 
235 aa  115  3.9999999999999997e-25  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.100456  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  36.51 
 
 
223 aa  115  5e-25  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_013170  Ccur_08240  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  46.4 
 
 
236 aa  115  5e-25  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.956318  normal  0.778898 
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  36.51 
 
 
223 aa  115  5e-25  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_005957  BT9727_1191  response regulator  36.51 
 
 
223 aa  115  6.9999999999999995e-25  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  36.51 
 
 
223 aa  115  8.999999999999998e-25  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  36.51 
 
 
223 aa  115  8.999999999999998e-25  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  36.51 
 
 
223 aa  115  8.999999999999998e-25  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_009513  Lreu_0019  two component transcriptional regulator  47.54 
 
 
235 aa  114  1.0000000000000001e-24  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  34.92 
 
 
223 aa  114  1.0000000000000001e-24  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  38.71 
 
 
232 aa  115  1.0000000000000001e-24  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  38.83 
 
 
235 aa  114  2.0000000000000002e-24  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_009455  DehaBAV1_0955  two component transcriptional regulator  52 
 
 
223 aa  113  2.0000000000000002e-24  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  38.83 
 
 
235 aa  113  3e-24  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  38.83 
 
 
235 aa  113  3e-24  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_005957  BT9727_5147  response regulator  38.83 
 
 
235 aa  113  3e-24  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_006274  BCZK5163  response regulator  38.83 
 
 
235 aa  113  3e-24  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  38.83 
 
 
235 aa  113  3e-24  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  38.83 
 
 
235 aa  113  3e-24  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  38.83 
 
 
235 aa  113  3e-24  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  38.83 
 
 
235 aa  113  3e-24  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_009092  Shew_3419  two component transcriptional regulator  35.11 
 
 
242 aa  113  3e-24  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  38.83 
 
 
235 aa  113  3e-24  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  36.79 
 
 
239 aa  112  5e-24  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  35.98 
 
 
223 aa  112  6e-24  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  35.98 
 
 
223 aa  112  7.000000000000001e-24  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  38.3 
 
 
235 aa  112  7.000000000000001e-24  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_013411  GYMC61_3538  two component transcriptional regulator, winged helix family  36.98 
 
 
237 aa  112  8.000000000000001e-24  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_008699  Noca_2939  response regulator receiver  40.64 
 
 
232 aa  111  1.0000000000000001e-23  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  33.64 
 
 
226 aa  111  1.0000000000000001e-23  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  39.67 
 
 
231 aa  110  2.0000000000000002e-23  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_4602  two component transcriptional regulator, winged helix family  36.65 
 
 
226 aa  109  3e-23  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_3409  two component transcriptional regulator, winged helix family  37.43 
 
 
236 aa  108  8.000000000000001e-23  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  38.24 
 
 
235 aa  108  8.000000000000001e-23  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013204  Elen_2015  putative two component transcriptional regulator, winged helix family  40.78 
 
 
224 aa  108  9.000000000000001e-23  Eggerthella lenta DSM 2243  Bacteria  normal  0.0839248  hitchhiker  0.0000000000000188648 
 
 
-
 
NC_013235  Namu_2566  two component transcriptional regulator, winged helix family  48.25 
 
 
229 aa  108  9.000000000000001e-23  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.000356007  hitchhiker  0.00345607 
 
 
-
 
NC_012793  GWCH70_1924  two component transcriptional regulator, winged helix family  35.38 
 
 
225 aa  107  2e-22  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  36.32 
 
 
226 aa  107  2e-22  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_002976  SERP2534  DNA-binding response regulator YycF  36.79 
 
 
233 aa  106  3e-22  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  33.84 
 
 
236 aa  106  3e-22  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_013169  Ksed_03700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  34.62 
 
 
226 aa  106  3e-22  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.132847 
 
 
-
 
NC_008530  LGAS_0064  DNA-binding response regulator  46.34 
 
 
235 aa  107  3e-22  Lactobacillus gasseri ATCC 33323  Bacteria  normal  0.611294  normal 
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  35.56 
 
 
228 aa  106  3e-22  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  36.04 
 
 
236 aa  106  4e-22  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_3085  two component transcriptional regulator, winged helix family  39.02 
 
 
232 aa  106  4e-22  Desulfotomaculum acetoxidans DSM 771  Bacteria  unclonable  0.00000000315463  hitchhiker  0.000599707 
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  36.13 
 
 
229 aa  105  5e-22  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  36.36 
 
 
227 aa  105  5e-22  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_011830  Dhaf_1756  two component transcriptional regulator, winged helix family  33.88 
 
 
230 aa  105  6e-22  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.769657  n/a   
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  36.13 
 
 
226 aa  105  6e-22  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_007333  Tfu_0257  response regulator receiver  39.11 
 
 
241 aa  105  7e-22  Thermobifida fusca YX  Bacteria  normal  0.926332  n/a   
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  34.54 
 
 
240 aa  105  7e-22  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_011830  Dhaf_2286  two component transcriptional regulator, winged helix family  35.75 
 
 
231 aa  105  7e-22  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000000000188753  n/a   
 
 
-
 
NC_010001  Cphy_3429  two component transcriptional regulator  33.33 
 
 
233 aa  104  1e-21  Clostridium phytofermentans ISDg  Bacteria  normal  0.0608192  n/a   
 
 
-
 
NC_013037  Dfer_0274  two component transcriptional regulator, winged helix family  30.63 
 
 
232 aa  103  2e-21  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.701823  normal  0.83989 
 
 
-
 
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