More than 300 homologs were found in PanDaTox collection
for query gene Nther_1220 on replicon NC_010718
Organism: Natranaerobius thermophilus JW/NM-WN-LF



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010718  Nther_1220  two component transcriptional regulator, winged helix family  100 
 
 
233 aa  474  1e-133  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  hitchhiker  0.00991602 
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  50.66 
 
 
223 aa  234  1.0000000000000001e-60  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  51.09 
 
 
228 aa  232  4.0000000000000004e-60  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  50 
 
 
228 aa  229  3e-59  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  46.98 
 
 
239 aa  222  4e-57  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_008262  CPR_2497  DNA-binding response regulator  49.34 
 
 
228 aa  221  9e-57  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP1055  DNA-binding response regulator SrrA  48.72 
 
 
241 aa  220  9.999999999999999e-57  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_3739  two component transcriptional regulator, winged helix family  46.67 
 
 
230 aa  220  1.9999999999999999e-56  Desulfitobacterium hafniense DCB-2  Bacteria  decreased coverage  0.0000000000466515  n/a   
 
 
-
 
NC_008261  CPF_2811  DNA-binding response regulator  49.34 
 
 
228 aa  219  1.9999999999999999e-56  Clostridium perfringens ATCC 13124  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  48.25 
 
 
227 aa  218  3.9999999999999997e-56  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  47.37 
 
 
237 aa  218  5e-56  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  47.53 
 
 
231 aa  218  8.999999999999998e-56  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  50.22 
 
 
236 aa  217  2e-55  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_1580  response regulator receiver  46.38 
 
 
241 aa  215  5e-55  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_1549  two component transcriptional regulator  46.38 
 
 
241 aa  215  5e-55  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_1897  two component transcriptional regulator  48.46 
 
 
227 aa  213  2.9999999999999995e-54  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.151466  n/a   
 
 
-
 
NC_009253  Dred_1903  two component transcriptional regulator  48.29 
 
 
230 aa  212  3.9999999999999995e-54  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_008554  Sfum_2892  two component transcriptional regulator  42.98 
 
 
227 aa  210  1e-53  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal  0.0239565 
 
 
-
 
NC_009253  Dred_2981  two component transcriptional regulator  47.41 
 
 
229 aa  210  1e-53  Desulfotomaculum reducens MI-1  Bacteria  unclonable  0.0000000201285  n/a   
 
 
-
 
NC_010001  Cphy_0154  two component transcriptional regulator  44.73 
 
 
238 aa  209  2e-53  Clostridium phytofermentans ISDg  Bacteria  normal  0.644268  n/a   
 
 
-
 
NC_011898  Ccel_1658  two component transcriptional regulator, winged helix family  45.92 
 
 
230 aa  209  4e-53  Clostridium cellulolyticum H10  Bacteria  normal  0.515101  n/a   
 
 
-
 
NC_007644  Moth_0827  two component transcriptional regulator  47.16 
 
 
256 aa  207  8e-53  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00211389  normal  0.244563 
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  48.02 
 
 
236 aa  207  1e-52  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_013216  Dtox_4198  two component transcriptional regulator, winged helix family  43.97 
 
 
226 aa  207  1e-52  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  47.62 
 
 
237 aa  206  2e-52  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  47.39 
 
 
223 aa  206  3e-52  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  47.39 
 
 
223 aa  206  3e-52  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  44.44 
 
 
235 aa  206  3e-52  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  47.14 
 
 
236 aa  205  4e-52  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  48.02 
 
 
240 aa  205  5e-52  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_013205  Aaci_1728  two component transcriptional regulator, winged helix family  44.92 
 
 
233 aa  205  6e-52  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  47.39 
 
 
223 aa  205  6e-52  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  47.39 
 
 
223 aa  205  6e-52  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  47.39 
 
 
223 aa  205  6e-52  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011830  Dhaf_0940  two component transcriptional regulator, winged helix family  48.89 
 
 
237 aa  204  7e-52  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.324642  n/a   
 
 
-
 
NC_013205  Aaci_2570  two component transcriptional regulator, winged helix family  44.92 
 
 
239 aa  204  7e-52  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_1191  response regulator  46.96 
 
 
223 aa  204  9e-52  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  47.39 
 
 
223 aa  203  1e-51  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  41.92 
 
 
229 aa  204  1e-51  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  47.39 
 
 
223 aa  204  1e-51  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  45.78 
 
 
229 aa  204  1e-51  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  46.46 
 
 
226 aa  204  1e-51  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  46.96 
 
 
223 aa  203  2e-51  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  46.96 
 
 
223 aa  203  2e-51  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  48.7 
 
 
223 aa  203  2e-51  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  45.58 
 
 
229 aa  202  3e-51  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_011899  Hore_13280  two component transcriptional regulator, winged helix family  46.26 
 
 
227 aa  202  3e-51  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000536961  n/a   
 
 
-
 
NC_008262  CPR_0609  DNA-binding response regulator  46.49 
 
 
231 aa  202  3e-51  Clostridium perfringens SM101  Bacteria  hitchhiker  0.0000282114  n/a   
 
 
-
 
NC_010320  Teth514_0766  two component transcriptional regulator  46.7 
 
 
231 aa  202  4e-51  Thermoanaerobacter sp. X514  Bacteria  normal  0.585906  n/a   
 
 
-
 
NC_007519  Dde_2387  two component transcriptional regulator  43.04 
 
 
229 aa  202  4e-51  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  hitchhiker  0.00115026  n/a   
 
 
-
 
NC_010320  Teth514_0439  two component transcriptional regulator  46.67 
 
 
225 aa  202  4e-51  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000223011  n/a   
 
 
-
 
NC_011831  Cagg_2709  two component transcriptional regulator, winged helix family  44.49 
 
 
236 aa  202  5e-51  Chloroflexus aggregans DSM 9485  Bacteria  decreased coverage  0.0011921  normal 
 
 
-
 
NC_010320  Teth514_1155  two component transcriptional regulator  46.49 
 
 
231 aa  201  6e-51  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000430064  n/a   
 
 
-
 
NC_013411  GYMC61_1696  two component transcriptional regulator, winged helix family  44.49 
 
 
224 aa  201  6e-51  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009523  RoseRS_3737  two component transcriptional regulator  43.29 
 
 
231 aa  201  6e-51  Roseiflexus sp. RS-1  Bacteria  normal  hitchhiker  0.00273603 
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  44.05 
 
 
226 aa  201  7e-51  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_002976  SERP1256  alkaline phosphatase synthesis transcriptional regulatory protein PhoP  45.3 
 
 
236 aa  201  8e-51  Staphylococcus epidermidis RP62A  Bacteria  normal  0.577358  n/a   
 
 
-
 
NC_010424  Daud_1419  two component transcriptional regulator  43.23 
 
 
231 aa  201  8e-51  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0720218  n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  44.3 
 
 
226 aa  201  9e-51  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_005957  BT9727_0255  DNA-binding response regulator  44.44 
 
 
237 aa  201  9.999999999999999e-51  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_2219  two component transcriptional regulator, winged helix family  45.64 
 
 
240 aa  200  9.999999999999999e-51  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_0393  two component transcriptional regulator, winged helix family  42.6 
 
 
227 aa  200  9.999999999999999e-51  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal  0.202895 
 
 
-
 
NC_009921  Franean1_6145  two component transcriptional regulator  43.48 
 
 
228 aa  200  9.999999999999999e-51  Frankia sp. EAN1pec  Bacteria  normal  normal  0.788201 
 
 
-
 
NC_008228  Patl_0218  two component transcriptional regulator  41.74 
 
 
239 aa  200  9.999999999999999e-51  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_0905  two component transcriptional regulator  43.59 
 
 
238 aa  200  9.999999999999999e-51  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_2106  two component transcriptional regulator, winged helix family  44.21 
 
 
238 aa  200  9.999999999999999e-51  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  44.1 
 
 
229 aa  200  1.9999999999999998e-50  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_010184  BcerKBAB4_0266  two component transcriptional regulator  44.44 
 
 
237 aa  200  1.9999999999999998e-50  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.262207  n/a   
 
 
-
 
NC_005945  BAS0273  DNA-binding response regulator  44.44 
 
 
237 aa  200  1.9999999999999998e-50  Bacillus anthracis str. Sterne  Bacteria  normal  0.484752  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1399  two component transcriptional regulator  44.12 
 
 
238 aa  200  1.9999999999999998e-50  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.129694  n/a   
 
 
-
 
NC_007530  GBAA_0287  DNA-binding response regulator  44.44 
 
 
237 aa  200  1.9999999999999998e-50  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.42222  n/a   
 
 
-
 
NC_013947  Snas_0580  two component transcriptional regulator, winged helix family  44.69 
 
 
226 aa  200  1.9999999999999998e-50  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_4046  response regulator receiver  43.81 
 
 
225 aa  200  1.9999999999999998e-50  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_0317  DNA-binding response regulator  44.44 
 
 
237 aa  200  1.9999999999999998e-50  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_012793  GWCH70_1924  two component transcriptional regulator, winged helix family  44.78 
 
 
225 aa  199  3e-50  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_0467  two component transcriptional regulator, winged helix family  42.49 
 
 
230 aa  199  3e-50  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_013124  Afer_0200  two component transcriptional regulator, winged helix family  45.37 
 
 
242 aa  199  3e-50  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  0.0955644  n/a   
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  42.24 
 
 
232 aa  199  3e-50  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_1237  two component transcriptional regulator, winged helix family  43.61 
 
 
234 aa  199  3.9999999999999996e-50  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.178035  n/a   
 
 
-
 
NC_006274  BCZK0258  response regulator  43.59 
 
 
237 aa  199  3.9999999999999996e-50  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  46.02 
 
 
236 aa  199  3.9999999999999996e-50  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_009674  Bcer98_0264  two component transcriptional regulator  43.59 
 
 
238 aa  199  3.9999999999999996e-50  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.392693  n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  44.64 
 
 
234 aa  198  6e-50  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  44.64 
 
 
234 aa  198  6e-50  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  44.05 
 
 
228 aa  198  6e-50  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  43.78 
 
 
232 aa  198  6e-50  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_0882  two component transcriptional regulator, winged helix family  42.17 
 
 
230 aa  198  7e-50  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.148935 
 
 
-
 
NC_010718  Nther_0984  two component transcriptional regulator, winged helix family  41.32 
 
 
246 aa  197  7.999999999999999e-50  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.0723779 
 
 
-
 
NC_008751  Dvul_1911  two component transcriptional regulator  42.31 
 
 
229 aa  197  7.999999999999999e-50  Desulfovibrio vulgaris DP4  Bacteria  normal  normal  0.258551 
 
 
-
 
NC_012034  Athe_0080  two component transcriptional regulator, winged helix family  42.79 
 
 
230 aa  197  9e-50  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_1601  DNA-binding response regulator ResD  43.28 
 
 
250 aa  197  1.0000000000000001e-49  Bacillus cereus ATCC 10987  Bacteria  normal  0.953648  n/a   
 
 
-
 
NC_005945  BAS1386  DNA-binding response regulator ResD  43.28 
 
 
238 aa  197  1.0000000000000001e-49  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_1359  response regulator  43.28 
 
 
238 aa  197  1.0000000000000001e-49  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.0319788  n/a   
 
 
-
 
NC_011773  BCAH820_1569  DNA-binding response regulator ResD  43.28 
 
 
250 aa  197  1.0000000000000001e-49  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.45334e-32 
 
 
-
 
NC_007530  GBAA_1497  DNA-binding response regulator ResD  43.28 
 
 
238 aa  197  1.0000000000000001e-49  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.862661  n/a   
 
 
-
 
NC_011772  BCG9842_B3814  DNA-binding response regulator ResD  43.28 
 
 
238 aa  197  1.0000000000000001e-49  Bacillus cereus G9842  Bacteria  normal  hitchhiker  3.95849e-16 
 
 
-
 
NC_010180  BcerKBAB4_5511  two component transcriptional regulator  44.16 
 
 
236 aa  197  1.0000000000000001e-49  Bacillus weihenstephanensis KBAB4  Bacteria  normal  normal  0.567595 
 
 
-
 
NC_011899  Hore_04710  two component transcriptional regulator, winged helix family  43.72 
 
 
237 aa  197  1.0000000000000001e-49  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1637  DNA-binding response regulator ResD  43.28 
 
 
250 aa  197  1.0000000000000001e-49  Bacillus cereus AH187  Bacteria  normal  0.0246031  n/a   
 
 
-
 
NC_011725  BCB4264_A1531  DNA-binding response regulator ResD  43.28 
 
 
238 aa  197  1.0000000000000001e-49  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
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