More than 300 homologs were found in PanDaTox collection
for query gene GWCH70_2219 on replicon NC_012793
Organism: Geobacillus sp. WCH70



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_012793  GWCH70_2219  two component transcriptional regulator, winged helix family  100 
 
 
240 aa  484  1e-136  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_1200  two component transcriptional regulator  85.23 
 
 
238 aa  414  9.999999999999999e-116  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0402  two component transcriptional regulator, winged helix family  87.82 
 
 
241 aa  411  1e-114  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011772  BCG9842_B3814  DNA-binding response regulator ResD  84.39 
 
 
238 aa  404  1.0000000000000001e-112  Bacillus cereus G9842  Bacteria  normal  hitchhiker  3.95849e-16 
 
 
-
 
NC_011725  BCB4264_A1531  DNA-binding response regulator ResD  84.39 
 
 
238 aa  404  1.0000000000000001e-112  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1399  two component transcriptional regulator  84.81 
 
 
238 aa  405  1.0000000000000001e-112  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.129694  n/a   
 
 
-
 
NC_003909  BCE_1601  DNA-binding response regulator ResD  83.97 
 
 
250 aa  403  1e-111  Bacillus cereus ATCC 10987  Bacteria  normal  0.953648  n/a   
 
 
-
 
NC_005945  BAS1386  DNA-binding response regulator ResD  83.97 
 
 
238 aa  403  1e-111  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_1359  response regulator  83.97 
 
 
238 aa  403  1e-111  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.0319788  n/a   
 
 
-
 
NC_011773  BCAH820_1569  DNA-binding response regulator ResD  83.97 
 
 
250 aa  403  1e-111  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.45334e-32 
 
 
-
 
NC_006274  BCZK1358  response regulator  83.97 
 
 
238 aa  403  1e-111  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_1497  DNA-binding response regulator ResD  83.97 
 
 
238 aa  403  1e-111  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.862661  n/a   
 
 
-
 
NC_011658  BCAH187_A1637  DNA-binding response regulator ResD  83.97 
 
 
250 aa  403  1e-111  Bacillus cereus AH187  Bacteria  normal  0.0246031  n/a   
 
 
-
 
NC_009632  SaurJH1_1580  response regulator receiver  73.91 
 
 
241 aa  353  1e-96  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_1549  two component transcriptional regulator  73.91 
 
 
241 aa  353  1e-96  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP1055  DNA-binding response regulator SrrA  72.61 
 
 
241 aa  344  6e-94  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_1728  two component transcriptional regulator, winged helix family  62.82 
 
 
233 aa  308  5e-83  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_3739  two component transcriptional regulator, winged helix family  56.6 
 
 
230 aa  267  8.999999999999999e-71  Desulfitobacterium hafniense DCB-2  Bacteria  decreased coverage  0.0000000000466515  n/a   
 
 
-
 
NC_009253  Dred_1903  two component transcriptional regulator  55.22 
 
 
230 aa  258  6e-68  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_0827  two component transcriptional regulator  54.27 
 
 
256 aa  248  9e-65  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00211389  normal  0.244563 
 
 
-
 
NC_010424  Daud_1897  two component transcriptional regulator  55.02 
 
 
227 aa  247  1e-64  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.151466  n/a   
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  53.59 
 
 
237 aa  246  2e-64  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_3085  two component transcriptional regulator, winged helix family  54.94 
 
 
232 aa  236  2e-61  Desulfotomaculum acetoxidans DSM 771  Bacteria  unclonable  0.00000000315463  hitchhiker  0.000599707 
 
 
-
 
NC_009253  Dred_2981  two component transcriptional regulator  48.07 
 
 
229 aa  227  2e-58  Desulfotomaculum reducens MI-1  Bacteria  unclonable  0.0000000201285  n/a   
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  48.29 
 
 
228 aa  224  1e-57  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_011830  Dhaf_0940  two component transcriptional regulator, winged helix family  49.12 
 
 
237 aa  221  4.9999999999999996e-57  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.324642  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  50.85 
 
 
232 aa  222  4.9999999999999996e-57  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_1924  two component transcriptional regulator, winged helix family  49.78 
 
 
225 aa  219  3e-56  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_4198  two component transcriptional regulator, winged helix family  48.07 
 
 
226 aa  218  7e-56  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  47.21 
 
 
223 aa  218  8.999999999999998e-56  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  47.21 
 
 
223 aa  218  8.999999999999998e-56  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  47.83 
 
 
223 aa  217  1e-55  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_1367  two component transcriptional regulator, winged helix family  50.66 
 
 
230 aa  217  1e-55  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000177207  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  47.41 
 
 
223 aa  216  2.9999999999999998e-55  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  47.83 
 
 
223 aa  216  2.9999999999999998e-55  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_008262  CPR_2497  DNA-binding response regulator  50 
 
 
228 aa  216  2.9999999999999998e-55  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  48.09 
 
 
228 aa  215  5e-55  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_008261  CPF_2811  DNA-binding response regulator  49.57 
 
 
228 aa  215  5.9999999999999996e-55  Clostridium perfringens ATCC 13124  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK0258  response regulator  47.01 
 
 
237 aa  214  7e-55  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  46.35 
 
 
223 aa  214  8e-55  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  46.35 
 
 
223 aa  214  8e-55  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  46.35 
 
 
223 aa  214  9e-55  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  46.35 
 
 
223 aa  214  9e-55  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  47.9 
 
 
236 aa  214  9.999999999999999e-55  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_1191  response regulator  46.96 
 
 
223 aa  214  9.999999999999999e-55  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_0264  two component transcriptional regulator  46.38 
 
 
238 aa  214  9.999999999999999e-55  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.392693  n/a   
 
 
-
 
NC_011725  BCB4264_A0316  DNA-binding response regulator  45.76 
 
 
237 aa  213  2.9999999999999995e-54  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B4998  DNA-binding response regulator  45.76 
 
 
237 aa  212  3.9999999999999995e-54  Bacillus cereus G9842  Bacteria  normal  0.709524  normal 
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  47.6 
 
 
223 aa  212  4.9999999999999996e-54  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_010184  BcerKBAB4_0266  two component transcriptional regulator  46.81 
 
 
237 aa  212  4.9999999999999996e-54  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.262207  n/a   
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  46.98 
 
 
223 aa  212  4.9999999999999996e-54  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1658  two component transcriptional regulator, winged helix family  48.48 
 
 
230 aa  211  5.999999999999999e-54  Clostridium cellulolyticum H10  Bacteria  normal  0.515101  n/a   
 
 
-
 
NC_010320  Teth514_2216  two component transcriptional regulator  48.26 
 
 
224 aa  211  7.999999999999999e-54  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  47.39 
 
 
227 aa  211  7.999999999999999e-54  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_011830  Dhaf_1285  two component transcriptional regulator, winged helix family  47.37 
 
 
234 aa  210  1e-53  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.477652  n/a   
 
 
-
 
NC_010001  Cphy_0154  two component transcriptional regulator  46.35 
 
 
238 aa  210  1e-53  Clostridium phytofermentans ISDg  Bacteria  normal  0.644268  n/a   
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  47.28 
 
 
237 aa  209  3e-53  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  49.13 
 
 
240 aa  209  3e-53  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_005945  BAS0273  DNA-binding response regulator  45.45 
 
 
237 aa  208  7e-53  Bacillus anthracis str. Sterne  Bacteria  normal  0.484752  n/a   
 
 
-
 
NC_007530  GBAA_0287  DNA-binding response regulator  45.45 
 
 
237 aa  208  7e-53  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.42222  n/a   
 
 
-
 
NC_011773  BCAH820_0317  DNA-binding response regulator  45.45 
 
 
237 aa  208  7e-53  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  46.72 
 
 
229 aa  208  7e-53  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_013595  Sros_0132  response regulator receiver protein  44.59 
 
 
231 aa  207  1e-52  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  47.81 
 
 
229 aa  207  1e-52  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_005957  BT9727_0255  DNA-binding response regulator  45.45 
 
 
237 aa  206  2e-52  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_0588  two component transcriptional regulator, winged helix family  48.71 
 
 
226 aa  206  2e-52  Geobacter lovleyi SZ  Bacteria  normal  0.944339  n/a   
 
 
-
 
NC_008261  CPF_2180  DNA-binding response regulator  46.72 
 
 
223 aa  205  4e-52  Clostridium perfringens ATCC 13124  Bacteria  normal  0.0299585  n/a   
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  47.39 
 
 
236 aa  205  4e-52  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_011830  Dhaf_1756  two component transcriptional regulator, winged helix family  46.15 
 
 
230 aa  205  5e-52  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.769657  n/a   
 
 
-
 
NC_008262  CPR_1891  DNA-binding response regulator  46.72 
 
 
223 aa  205  5e-52  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  47.16 
 
 
236 aa  204  7e-52  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  46.93 
 
 
232 aa  204  1e-51  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  47.83 
 
 
232 aa  204  1e-51  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_5259  two component transcriptional regulator  48.23 
 
 
235 aa  203  2e-51  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.000559572  n/a   
 
 
-
 
NC_010001  Cphy_2855  two component transcriptional regulator  43.83 
 
 
224 aa  203  2e-51  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.0000000952101  n/a   
 
 
-
 
NC_010180  BcerKBAB4_5511  two component transcriptional regulator  47.6 
 
 
236 aa  203  2e-51  Bacillus weihenstephanensis KBAB4  Bacteria  normal  normal  0.567595 
 
 
-
 
NC_011899  Hore_13280  two component transcriptional regulator, winged helix family  47.62 
 
 
227 aa  203  2e-51  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000536961  n/a   
 
 
-
 
NC_003909  BCE_5615  DNA-binding response regulator YycF  48.23 
 
 
235 aa  202  3e-51  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS5319  DNA-binding response regulator YycF  48.23 
 
 
235 aa  202  3e-51  Bacillus anthracis str. Sterne  Bacteria  normal  0.169223  n/a   
 
 
-
 
NC_011773  BCAH820_5572  DNA-binding response regulator YycF  48.23 
 
 
235 aa  202  3e-51  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  1.81316e-29 
 
 
-
 
NC_005957  BT9727_5147  response regulator  48.23 
 
 
235 aa  202  3e-51  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.00168683  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  45.26 
 
 
235 aa  202  3e-51  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_006274  BCZK5163  response regulator  48.23 
 
 
235 aa  202  3e-51  Bacillus cereus E33L  Bacteria  hitchhiker  0.00196509  n/a   
 
 
-
 
NC_007530  GBAA_5715  DNA-binding response regulator YycF  48.23 
 
 
235 aa  202  3e-51  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.656882  n/a   
 
 
-
 
NC_011898  Ccel_0246  two component transcriptional regulator, winged helix family  42.17 
 
 
225 aa  202  3e-51  Clostridium cellulolyticum H10  Bacteria  normal  0.0272164  n/a   
 
 
-
 
NC_011658  BCAH187_A5650  DNA-binding response regulator YycF  48.23 
 
 
235 aa  202  3e-51  Bacillus cereus AH187  Bacteria  hitchhiker  0.00563499  n/a   
 
 
-
 
NC_011830  Dhaf_2286  two component transcriptional regulator, winged helix family  45.85 
 
 
231 aa  203  3e-51  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000000000188753  n/a   
 
 
-
 
NC_011830  Dhaf_2193  two component transcriptional regulator, winged helix family  42.92 
 
 
237 aa  202  4e-51  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0620475  n/a   
 
 
-
 
NC_011772  BCG9842_B5346  DNA-binding response regulator YycF  48.23 
 
 
235 aa  202  5e-51  Bacillus cereus G9842  Bacteria  hitchhiker  0.000000234523  hitchhiker  0.00000000000323141 
 
 
-
 
NC_009674  Bcer98_4006  two component transcriptional regulator  48.23 
 
 
235 aa  202  5e-51  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.010356  n/a   
 
 
-
 
NC_011725  BCB4264_A5589  DNA-binding response regulator YycF  48.23 
 
 
235 aa  202  5e-51  Bacillus cereus B4264  Bacteria  normal  0.0469644  n/a   
 
 
-
 
NC_011899  Hore_04710  two component transcriptional regulator, winged helix family  46.32 
 
 
237 aa  201  6e-51  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_3302  two component transcriptional regulator, winged helix family  45.81 
 
 
231 aa  201  7e-51  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.000343135 
 
 
-
 
NC_011898  Ccel_3394  two component transcriptional regulator, winged helix family  47.19 
 
 
230 aa  201  9.999999999999999e-51  Clostridium cellulolyticum H10  Bacteria  normal  0.103692  n/a   
 
 
-
 
NC_009487  SaurJH9_0018  two component transcriptional regulator  45.89 
 
 
233 aa  201  9.999999999999999e-51  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.70243  n/a   
 
 
-
 
NC_009632  SaurJH1_0018  response regulator receiver  45.89 
 
 
233 aa  201  9.999999999999999e-51  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_0721  two component transcriptional regulator, winged helix family  45.53 
 
 
233 aa  200  9.999999999999999e-51  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.811558  normal 
 
 
-
 
NC_013216  Dtox_1554  two component transcriptional regulator, winged helix family  43.23 
 
 
229 aa  199  1.9999999999999998e-50  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  hitchhiker  0.00709514 
 
 
-
 
NC_010718  Nther_1220  two component transcriptional regulator, winged helix family  45.64 
 
 
233 aa  200  1.9999999999999998e-50  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  hitchhiker  0.00991602 
 
 
-
 
NC_011769  DvMF_0882  two component transcriptional regulator, winged helix family  46.55 
 
 
230 aa  199  1.9999999999999998e-50  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.148935 
 
 
-
 
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