More than 300 homologs were found in PanDaTox collection
for query gene Pcar_2303 on replicon NC_007498
Organism: Pelobacter carbinolicus DSM 2380



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_007498  Pcar_2303  putative methyl-accepting chemotaxis protein (MCP)  100 
 
 
730 aa  1466    Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_1372  putative methyl-accepting chemotaxis protein (MCP)  49.27 
 
 
706 aa  317  7e-85  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_1336  putative methyl-accepting chemotaxis protein (MCP)  43.97 
 
 
740 aa  293  5e-78  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.00000000730785  n/a   
 
 
-
 
NC_007498  Pcar_1355  putative methyl-accepting chemotaxis protein (MCP)  42.25 
 
 
744 aa  292  2e-77  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_2364  putative methyl-accepting chemotaxis protein (MCP)  44.74 
 
 
702 aa  241  5e-62  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_2967  methyl-accepting chemotaxis protein (MCP)  41.11 
 
 
695 aa  237  6e-61  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.000011738  n/a   
 
 
-
 
NC_009012  Cthe_0039  methyl-accepting chemotaxis sensory transducer  37.82 
 
 
623 aa  234  5e-60  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_1498  methyl-accepting chemotaxis sensory transducer  37.43 
 
 
602 aa  233  6e-60  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_0439  methyl-accepting chemotaxis protein (MCP)  40.11 
 
 
740 aa  223  7e-57  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_0613  methyl-accepting chemotaxis sensory transducer  37.18 
 
 
759 aa  213  7.999999999999999e-54  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal  0.194714 
 
 
-
 
NC_012034  Athe_1768  methyl-accepting chemotaxis sensory transducer  34.65 
 
 
516 aa  213  9e-54  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_0298  methyl-accepting chemotaxis sensory transducer  42.09 
 
 
600 aa  212  2e-53  Clostridium thermocellum ATCC 27405  Bacteria  unclonable  0.000000337227  n/a   
 
 
-
 
NC_009012  Cthe_3030  methyl-accepting chemotaxis sensory transducer  41.57 
 
 
832 aa  207  5e-52  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.00284544  n/a   
 
 
-
 
NC_007498  Pcar_0545  methyl-accepting chemotaxis protein (MCP)  40.05 
 
 
676 aa  207  7e-52  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  1.25556e-16  n/a   
 
 
-
 
NC_007498  Pcar_2607  methyl-accepting chemotaxis protein (MCP)  35.4 
 
 
741 aa  207  7e-52  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_0972  methyl-accepting chemotaxis protein (MCP)  37.5 
 
 
779 aa  206  1e-51  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.00000000000412028  n/a   
 
 
-
 
NC_011898  Ccel_2313  methyl-accepting chemotaxis sensory transducer  36.49 
 
 
567 aa  204  6e-51  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_2467  putative methyl-accepting chemotaxis protein (MCP)  38.35 
 
 
729 aa  203  8e-51  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_0585  methyl-accepting chemotaxis protein (MCP)  38.67 
 
 
706 aa  202  3e-50  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.0000000000000132912  n/a   
 
 
-
 
NC_011989  Avi_0793  methyl-accepting chemotaxis protein  32.1 
 
 
740 aa  189  2e-46  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_007404  Tbd_1622  methyl-accepting chemotaxis sensory transducer  37.02 
 
 
572 aa  186  2.0000000000000003e-45  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  0.415216  normal 
 
 
-
 
NC_012880  Dd703_2081  methyl-accepting chemotaxis sensory transducer  32.1 
 
 
668 aa  186  2.0000000000000003e-45  Dickeya dadantii Ech703  Bacteria  normal  0.622232  n/a   
 
 
-
 
NC_013421  Pecwa_4354  methyl-accepting chemotaxis sensory transducer  35.23 
 
 
555 aa  184  6e-45  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_007963  Csal_2019  methyl-accepting chemotaxis sensory transducer  32.17 
 
 
567 aa  183  9.000000000000001e-45  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_012912  Dd1591_1542  methyl-accepting chemotaxis sensory transducer  34.25 
 
 
566 aa  182  1e-44  Dickeya zeae Ech1591  Bacteria  normal  0.350049  n/a   
 
 
-
 
NC_007404  Tbd_0660  chemotaxis sensory transducer  36.87 
 
 
586 aa  182  1e-44  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  0.756829  normal 
 
 
-
 
NC_009654  Mmwyl1_0161  methyl-accepting chemotaxis sensory transducer  34.71 
 
 
661 aa  182  2e-44  Marinomonas sp. MWYL1  Bacteria  normal  normal  0.0270172 
 
 
-
 
NC_008700  Sama_3497  putative methyl-accepting chemotaxis sensory transducer  38.74 
 
 
860 aa  181  2.9999999999999997e-44  Shewanella amazonensis SB2B  Bacteria  normal  0.19961  normal 
 
 
-
 
NC_011080  SNSL254_A4887  methyl-accepting chemotaxis protein I  35.87 
 
 
553 aa  181  4.999999999999999e-44  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  normal 
 
 
-
 
NC_010625  Bphy_6319  methyl-accepting chemotaxis sensory transducer  32.78 
 
 
549 aa  181  4.999999999999999e-44  Burkholderia phymatum STM815  Bacteria  normal  0.249944  normal 
 
 
-
 
NC_011205  SeD_A4946  methyl-accepting chemotaxis protein I  35.87 
 
 
553 aa  181  4.999999999999999e-44  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  normal  0.556415 
 
 
-
 
NC_011083  SeHA_C4939  methyl-accepting chemotaxis protein I  35.87 
 
 
553 aa  181  4.999999999999999e-44  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  0.188217  normal 
 
 
-
 
NC_010506  Swoo_0164  methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor  35.64 
 
 
1123 aa  179  1e-43  Shewanella woodyi ATCC 51908  Bacteria  normal  normal 
 
 
-
 
NC_012880  Dd703_1569  methyl-accepting chemotaxis sensory transducer  34.31 
 
 
554 aa  179  1e-43  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_008752  Aave_1405  methyl-accepting chemotaxis sensory transducer  35.78 
 
 
548 aa  179  1e-43  Acidovorax citrulli AAC00-1  Bacteria  normal  normal 
 
 
-
 
NC_009636  Smed_0305  methyl-accepting chemotaxis sensory transducer  34.75 
 
 
841 aa  179  2e-43  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_009832  Spro_0080  methyl-accepting chemotaxis sensory transducer  33.24 
 
 
642 aa  178  2e-43  Serratia proteamaculans 568  Bacteria  normal  normal 
 
 
-
 
NC_012917  PC1_4071  methyl-accepting chemotaxis sensory transducer  34.66 
 
 
553 aa  179  2e-43  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_011094  SeSA_A4786  methyl-accepting chemotaxis protein I  35.56 
 
 
553 aa  179  2e-43  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.709187  normal 
 
 
-
 
NC_008825  Mpe_A2548  methyl-accepting chemotaxis protein  33.19 
 
 
525 aa  179  2e-43  Methylibium petroleiphilum PM1  Bacteria  decreased coverage  0.00975221  normal  0.500866 
 
 
-
 
NC_010001  Cphy_1172  methyl-accepting chemotaxis sensory transducer  31.44 
 
 
562 aa  178  3e-43  Clostridium phytofermentans ISDg  Bacteria  unclonable  0.00000023446  n/a   
 
 
-
 
NC_007908  Rfer_2225  methyl-accepting chemotaxis sensory transducer  32.99 
 
 
583 aa  177  5e-43  Rhodoferax ferrireducens T118  Bacteria  normal  0.220406  n/a   
 
 
-
 
NC_008061  Bcen_4628  methyl-accepting chemotaxis sensory transducer  36.68 
 
 
620 aa  177  5e-43  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_008543  Bcen2424_3736  methyl-accepting chemotaxis sensory transducer  36.68 
 
 
620 aa  177  6e-43  Burkholderia cenocepacia HI2424  Bacteria  normal  0.455432  normal  0.0212994 
 
 
-
 
NC_009831  Ssed_0184  methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor  35.64 
 
 
863 aa  177  6e-43  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_012880  Dd703_0727  methyl-accepting chemotaxis sensory transducer  34.38 
 
 
559 aa  177  6e-43  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_010515  Bcenmc03_3785  methyl-accepting chemotaxis sensory transducer  36.79 
 
 
620 aa  177  7e-43  Burkholderia cenocepacia MC0-3  Bacteria  hitchhiker  0.0060774  normal  0.0147123 
 
 
-
 
NC_013421  Pecwa_2019  methyl-accepting chemotaxis sensory transducer  31.18 
 
 
644 aa  176  9.999999999999999e-43  Pectobacterium wasabiae WPP163  Bacteria  normal  0.858801  n/a   
 
 
-
 
NC_011989  Avi_3729  methyl-accepting chemotaxis protein  32.66 
 
 
644 aa  176  9.999999999999999e-43  Agrobacterium vitis S4  Bacteria  normal  0.554142  n/a   
 
 
-
 
NC_010001  Cphy_0285  methyl-accepting chemotaxis sensory transducer  31.69 
 
 
711 aa  176  9.999999999999999e-43  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_011989  Avi_1201  methyl-accepting chemotaxis protein  32.13 
 
 
728 aa  176  9.999999999999999e-43  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_007963  Csal_2022  methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor  32.43 
 
 
748 aa  176  9.999999999999999e-43  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_012791  Vapar_4189  methyl-accepting chemotaxis sensory transducer  35.36 
 
 
559 aa  176  1.9999999999999998e-42  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_010498  EcSMS35_4900  methyl-accepting chemotaxis protein I  35.67 
 
 
554 aa  175  1.9999999999999998e-42  Escherichia coli SMS-3-5  Bacteria  normal  normal  0.979291 
 
 
-
 
NC_007963  Csal_1989  methyl-accepting chemotaxis sensory transducer  33.14 
 
 
556 aa  176  1.9999999999999998e-42  Chromohalobacter salexigens DSM 3043  Bacteria  decreased coverage  0.00286784  n/a   
 
 
-
 
NC_011353  ECH74115_5868  methyl-accepting chemotaxis protein I  35.67 
 
 
554 aa  175  1.9999999999999998e-42  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  normal 
 
 
-
 
NC_011989  Avi_1547  methyl-accepting chemotaxis protein  32.37 
 
 
635 aa  176  1.9999999999999998e-42  Agrobacterium vitis S4  Bacteria  normal  0.0672502  n/a   
 
 
-
 
NC_009800  EcHS_A4586  methyl-accepting chemotaxis protein I  35.67 
 
 
557 aa  175  1.9999999999999998e-42  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_4947  methyl-accepting chemotaxis protein I  35.67 
 
 
554 aa  175  1.9999999999999998e-42  Escherichia coli E24377A  Bacteria  normal  n/a   
 
 
-
 
NC_009832  Spro_2983  methyl-accepting chemotaxis sensory transducer  34.76 
 
 
556 aa  175  1.9999999999999998e-42  Serratia proteamaculans 568  Bacteria  normal  0.96835  normal 
 
 
-
 
CP001509  ECD_04232  methyl-accepting chemotaxis protein I, serine sensor receptor  35.67 
 
 
551 aa  175  2.9999999999999996e-42  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
CP001637  EcDH1_3642  methyl-accepting chemotaxis sensory transducer  35.67 
 
 
551 aa  175  2.9999999999999996e-42  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_012892  B21_04198  hypothetical protein  35.67 
 
 
551 aa  175  2.9999999999999996e-42  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_007908  Rfer_2507  methyl-accepting chemotaxis sensory transducer  30.9 
 
 
589 aa  175  2.9999999999999996e-42  Rhodoferax ferrireducens T118  Bacteria  normal  0.197123  n/a   
 
 
-
 
NC_012912  Dd1591_1879  methyl-accepting chemotaxis sensory transducer  32.77 
 
 
661 aa  175  2.9999999999999996e-42  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_3700  methyl-accepting chemotaxis sensory transducer  35.67 
 
 
554 aa  175  2.9999999999999996e-42  Escherichia coli ATCC 8739  Bacteria  normal  normal  0.125609 
 
 
-
 
NC_009092  Shew_0111  methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor  36.86 
 
 
864 aa  175  2.9999999999999996e-42  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_3834  methyl-accepting chemotaxis sensory transducer  33.01 
 
 
595 aa  175  2.9999999999999996e-42  Delftia acidovorans SPH-1  Bacteria  normal  0.10184  normal  0.0113192 
 
 
-
 
NC_008752  Aave_0407  methyl-accepting chemotaxis sensory transducer  35.57 
 
 
525 aa  175  2.9999999999999996e-42  Acidovorax citrulli AAC00-1  Bacteria  normal  0.770374  normal 
 
 
-
 
NC_012917  PC1_1417  methyl-accepting chemotaxis sensory transducer  32.4 
 
 
554 aa  175  2.9999999999999996e-42  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.37293  n/a   
 
 
-
 
NC_008346  Swol_1331  putative methyl-accepting chemotaxis sensory transducer  45.12 
 
 
370 aa  174  3.9999999999999995e-42  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_007520  Tcr_1984  methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor  32.88 
 
 
954 aa  174  5e-42  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_009049  Rsph17029_1679  methyl-accepting chemotaxis sensory transducer  39.85 
 
 
567 aa  174  5e-42  Rhodobacter sphaeroides ATCC 17029  Bacteria  decreased coverage  0.00756362  hitchhiker  0.00632021 
 
 
-
 
NC_008391  Bamb_5471  methyl-accepting chemotaxis sensory transducer  36.05 
 
 
620 aa  174  5.999999999999999e-42  Burkholderia ambifaria AMMD  Bacteria  normal  0.407039  normal 
 
 
-
 
NC_012880  Dd703_1514  methyl-accepting chemotaxis sensory transducer  35.16 
 
 
562 aa  174  6.999999999999999e-42  Dickeya dadantii Ech703  Bacteria  normal  0.957025  n/a   
 
 
-
 
NC_009436  Ent638_0513  methyl-accepting chemotaxis sensory transducer  36.01 
 
 
586 aa  174  6.999999999999999e-42  Enterobacter sp. 638  Bacteria  normal  hitchhiker  0.00498581 
 
 
-
 
NC_012917  PC1_3443  methyl-accepting chemotaxis sensory transducer  30.88 
 
 
511 aa  174  6.999999999999999e-42  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.330959  n/a   
 
 
-
 
NC_007493  RSP_0044  putative cytoplasmic chemoreceptor, TlpT  39.85 
 
 
567 aa  174  6.999999999999999e-42  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.0134213  n/a   
 
 
-
 
NC_012912  Dd1591_0055  methyl-accepting chemotaxis sensory transducer  29.57 
 
 
628 aa  173  7.999999999999999e-42  Dickeya zeae Ech1591  Bacteria  normal  0.608397  n/a   
 
 
-
 
NC_008789  Hhal_2163  methyl-accepting chemotaxis sensory transducer  35.59 
 
 
610 aa  173  7.999999999999999e-42  Halorhodospira halophila SL1  Bacteria  normal  n/a   
 
 
-
 
NC_008825  Mpe_A0586  methyl-accepting chemotaxis sensory transducer  31.99 
 
 
584 aa  174  7.999999999999999e-42  Methylibium petroleiphilum PM1  Bacteria  normal  normal 
 
 
-
 
NC_013421  Pecwa_1857  methyl-accepting chemotaxis sensory transducer  34.56 
 
 
561 aa  173  1e-41  Pectobacterium wasabiae WPP163  Bacteria  normal  0.769355  n/a   
 
 
-
 
NC_007963  Csal_2778  methyl-accepting chemotaxis sensory transducer  40 
 
 
544 aa  173  1e-41  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.643433  n/a   
 
 
-
 
NC_010086  Bmul_4997  methyl-accepting chemotaxis sensory transducer  35.11 
 
 
620 aa  173  1e-41  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.245568 
 
 
-
 
NC_010581  Bind_3620  methyl-accepting chemotaxis sensory transducer  32.51 
 
 
677 aa  172  1e-41  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal  0.0125911 
 
 
-
 
NC_008782  Ajs_3087  methyl-accepting chemotaxis sensory transducer  34.02 
 
 
527 aa  173  1e-41  Acidovorax sp. JS42  Bacteria  normal  normal  0.823637 
 
 
-
 
NC_013421  Pecwa_1820  methyl-accepting chemotaxis sensory transducer  31.98 
 
 
553 aa  172  2e-41  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_1917  methyl-accepting chemotaxis sensory transducer  35.2 
 
 
677 aa  172  2e-41  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.134066  n/a   
 
 
-
 
NC_011989  Avi_1200  methyl-accepting chemotaxis protein  33.73 
 
 
728 aa  172  2e-41  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_2526  methyl-accepting chemotaxis sensory transducer  33.16 
 
 
554 aa  172  2e-41  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_010658  SbBS512_E4893  methyl-accepting chemotaxis protein I  35.37 
 
 
551 aa  172  2e-41  Shigella boydii CDC 3083-94  Bacteria  normal  n/a   
 
 
-
 
NC_012912  Dd1591_2086  methyl-accepting chemotaxis sensory transducer  31.09 
 
 
653 aa  172  2e-41  Dickeya zeae Ech1591  Bacteria  normal  0.0240769  n/a   
 
 
-
 
NC_010625  Bphy_6805  methyl-accepting chemotaxis sensory transducer  33.24 
 
 
499 aa  172  2e-41  Burkholderia phymatum STM815  Bacteria  normal  0.923818  normal 
 
 
-
 
NC_009078  BURPS1106A_A1623  methyl-accepting chemotaxis protein  40.28 
 
 
517 aa  171  3e-41  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_009075  BURPS668_A1710  methyl-accepting chemotaxis protein  40.28 
 
 
517 aa  171  3e-41  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_2223  methyl-accepting chemotaxis sensory transducer  29.44 
 
 
508 aa  171  3e-41  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_009428  Rsph17025_1632  methyl-accepting chemotaxis sensory transducer  38.77 
 
 
654 aa  171  3e-41  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal 
 
 
-
 
NC_012912  Dd1591_0769  methyl-accepting chemotaxis sensory transducer  32.39 
 
 
505 aa  172  3e-41  Dickeya zeae Ech1591  Bacteria  normal  0.0409416  n/a   
 
 
-
 
NC_007947  Mfla_2154  methyl-accepting chemotaxis sensory transducer  32.68 
 
 
569 aa  171  3e-41  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_0628  methyl-accepting chemotaxis sensory transducer  27.8 
 
 
675 aa  171  3e-41  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
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