More than 300 homologs were found in PanDaTox collection
for query gene Amir_5468 on replicon NC_013093
Organism: Actinosynnema mirum DSM 43827



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013093  Amir_5468  two component transcriptional regulator, winged helix family  100 
 
 
223 aa  436  1e-121  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_0102  response regulator receiver protein  66.67 
 
 
222 aa  288  4e-77  Streptosporangium roseum DSM 43021  Bacteria  normal  0.294663  normal 
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  62.27 
 
 
225 aa  271  8.000000000000001e-72  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_008699  Noca_1613  response regulator receiver  62.73 
 
 
225 aa  268  5e-71  Nocardioides sp. JS614  Bacteria  normal  0.97266  n/a   
 
 
-
 
NC_013595  Sros_3423  response regulator receiver protein  63.64 
 
 
224 aa  262  3e-69  Streptosporangium roseum DSM 43021  Bacteria  normal  0.699539  normal  0.107362 
 
 
-
 
NC_013521  Sked_37500  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  62.27 
 
 
225 aa  262  3e-69  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.0213695  normal 
 
 
-
 
NC_009664  Krad_1806  two component transcriptional regulator, winged helix family  61.82 
 
 
225 aa  258  4e-68  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0205791  normal  0.258829 
 
 
-
 
NC_008699  Noca_1598  response regulator receiver  60 
 
 
226 aa  257  9e-68  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_013124  Afer_0703  two component transcriptional regulator, winged helix family  58.11 
 
 
236 aa  254  1.0000000000000001e-66  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_008537  Arth_4535  two component transcriptional regulator  57.27 
 
 
227 aa  254  1.0000000000000001e-66  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_1324  response regulator receiver  59.55 
 
 
223 aa  251  7e-66  Gordonia bronchialis DSM 43247  Bacteria  normal  0.88989  n/a   
 
 
-
 
NC_013521  Sked_01690  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  57.47 
 
 
217 aa  227  1e-58  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.459553  normal  0.405302 
 
 
-
 
NC_013165  Shel_13760  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  53.6 
 
 
225 aa  226  1e-58  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_014151  Cfla_1294  two component transcriptional regulator, winged helix family  60.45 
 
 
218 aa  227  1e-58  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0476117  hitchhiker  0.00354598 
 
 
-
 
NC_014158  Tpau_1622  two component transcriptional regulator, winged helix family  57.47 
 
 
223 aa  224  7e-58  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.153936  n/a   
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  54.09 
 
 
235 aa  223  1e-57  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  54.55 
 
 
283 aa  223  2e-57  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_013947  Snas_4842  two component transcriptional regulator, winged helix family  55.45 
 
 
225 aa  222  3e-57  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.649395  normal 
 
 
-
 
NC_013739  Cwoe_0293  two component transcriptional regulator, winged helix family  51.82 
 
 
226 aa  217  1e-55  Conexibacter woesei DSM 14684  Bacteria  normal  0.591061  normal  0.658536 
 
 
-
 
NC_008699  Noca_1610  two component transcriptional regulator  50.91 
 
 
232 aa  217  1e-55  Nocardioides sp. JS614  Bacteria  normal  0.496365  n/a   
 
 
-
 
NC_009380  Strop_1594  response regulator receiver  57.85 
 
 
219 aa  209  3e-53  Salinispora tropica CNB-440  Bacteria  normal  0.349405  normal 
 
 
-
 
NC_009565  TBFG_10613  two component system DNA binding transcriptional regulatory protein tcrA  50.45 
 
 
253 aa  206  2e-52  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.0000000499525  normal  0.750249 
 
 
-
 
NC_002977  MCA2330  DNA-binding response regulator  48.64 
 
 
228 aa  206  3e-52  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_009953  Sare_1554  two component transcriptional regulator  56.36 
 
 
218 aa  205  6e-52  Salinispora arenicola CNS-205  Bacteria  normal  0.083917  hitchhiker  0.00805861 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  45.5 
 
 
223 aa  201  9e-51  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  45.95 
 
 
225 aa  201  9e-51  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_0753  two component transcriptional regulator, winged helix family  54.13 
 
 
241 aa  201  9.999999999999999e-51  Actinosynnema mirum DSM 43827  Bacteria  normal  0.407347  n/a   
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  46.15 
 
 
223 aa  198  3.9999999999999996e-50  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_1559  response regulator receiver  50.9 
 
 
228 aa  198  3.9999999999999996e-50  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  46.85 
 
 
240 aa  197  1.0000000000000001e-49  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_008699  Noca_2062  two component transcriptional regulator  50 
 
 
228 aa  197  1.0000000000000001e-49  Nocardioides sp. JS614  Bacteria  normal  0.0133309  n/a   
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  47.51 
 
 
225 aa  194  7e-49  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  47.51 
 
 
225 aa  194  1e-48  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  47.96 
 
 
225 aa  193  2e-48  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_010501  PputW619_4391  two component heavy metal response transcriptional regulator  48.2 
 
 
224 aa  193  2e-48  Pseudomonas putida W619  Bacteria  normal  normal  0.593256 
 
 
-
 
NC_013037  Dfer_0274  two component transcriptional regulator, winged helix family  43.17 
 
 
232 aa  192  3e-48  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.701823  normal  0.83989 
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  47.96 
 
 
225 aa  192  3e-48  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  47.51 
 
 
225 aa  192  3e-48  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  40.97 
 
 
230 aa  192  3e-48  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  47.96 
 
 
225 aa  192  3e-48  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  47.96 
 
 
225 aa  192  3e-48  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  44.39 
 
 
224 aa  192  4e-48  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  46.61 
 
 
231 aa  192  5e-48  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  47.3 
 
 
224 aa  191  7e-48  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_009486  Tpet_0521  two component transcriptional regulator  44.95 
 
 
223 aa  191  1e-47  Thermotoga petrophila RKU-1  Bacteria  normal  0.720367  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  44.49 
 
 
235 aa  189  2e-47  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  47.06 
 
 
225 aa  189  2.9999999999999997e-47  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_007974  Rmet_5331  transcriptional regulator two components regulatory system  45.29 
 
 
225 aa  189  4e-47  Cupriavidus metallidurans CH34  Bacteria  normal  0.0274603  normal 
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  43.05 
 
 
224 aa  188  7e-47  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  41.89 
 
 
223 aa  187  1e-46  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_007005  Psyr_1127  heavy metal response regulator  45.5 
 
 
225 aa  186  2e-46  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.294376  normal  0.216529 
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  45 
 
 
224 aa  186  2e-46  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  44.84 
 
 
224 aa  187  2e-46  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  44.59 
 
 
223 aa  187  2e-46  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  43.95 
 
 
224 aa  187  2e-46  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_010676  Bphyt_5873  two component heavy metal response transcriptional regulator, winged helix family  46.15 
 
 
228 aa  185  4e-46  Burkholderia phytofirmans PsJN  Bacteria  normal  0.247228  normal 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  45.25 
 
 
226 aa  186  4e-46  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B2069  two component heavy metal response transcriptional regulator  46.15 
 
 
228 aa  185  4e-46  Burkholderia xenovorans LB400  Bacteria  normal  0.0102482  normal 
 
 
-
 
NC_004578  PSPTO_1307  DNA-binding heavy metal response regulator  45.05 
 
 
225 aa  185  5e-46  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.150056  n/a   
 
 
-
 
NC_011772  BCG9842_B2033  DNA-binding response regulator  45 
 
 
224 aa  185  5e-46  Bacillus cereus G9842  Bacteria  normal  0.725953  normal 
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  45 
 
 
224 aa  185  5e-46  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  42.41 
 
 
223 aa  184  6e-46  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_010184  BcerKBAB4_2944  two component transcriptional regulator  45.45 
 
 
224 aa  185  6e-46  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0958095  n/a   
 
 
-
 
NC_013205  Aaci_2264  two component transcriptional regulator, winged helix family  47.95 
 
 
231 aa  184  7e-46  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  hitchhiker  0.00910741  n/a   
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  44.14 
 
 
230 aa  184  8e-46  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  40.62 
 
 
224 aa  184  8e-46  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  44.84 
 
 
226 aa  184  9e-46  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_008148  Rxyl_0187  two component transcriptional regulator  47.96 
 
 
227 aa  184  9e-46  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  42.79 
 
 
227 aa  184  1.0000000000000001e-45  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_010803  Clim_1291  two component transcriptional regulator, winged helix family  42.6 
 
 
222 aa  184  1.0000000000000001e-45  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_010625  Bphy_6519  two component heavy metal response transcriptional regulator  47.06 
 
 
228 aa  184  1.0000000000000001e-45  Burkholderia phymatum STM815  Bacteria  normal  normal  0.0435386 
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  45.21 
 
 
219 aa  184  1.0000000000000001e-45  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  46.15 
 
 
226 aa  184  1.0000000000000001e-45  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  43.44 
 
 
223 aa  183  2.0000000000000003e-45  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS2999  DNA-binding response regulator  44.09 
 
 
224 aa  183  2.0000000000000003e-45  Bacillus anthracis str. Sterne  Bacteria  normal  0.227145  n/a   
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  44.84 
 
 
228 aa  183  2.0000000000000003e-45  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007530  GBAA_3229  DNA-binding response regulator  44.09 
 
 
224 aa  183  2.0000000000000003e-45  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  44.84 
 
 
226 aa  182  2.0000000000000003e-45  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  44.39 
 
 
224 aa  182  3e-45  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  45.25 
 
 
226 aa  182  3e-45  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  43.95 
 
 
226 aa  182  4.0000000000000006e-45  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  44.59 
 
 
225 aa  182  4.0000000000000006e-45  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007575  Suden_0317  two component transcriptional regulator  40.54 
 
 
224 aa  182  4.0000000000000006e-45  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  44.8 
 
 
225 aa  182  5.0000000000000004e-45  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_008346  Swol_2177  response regulator receiver protein  44.39 
 
 
223 aa  182  5.0000000000000004e-45  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  decreased coverage  0.00323539  n/a   
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  43.95 
 
 
226 aa  181  7e-45  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_007794  Saro_1631  two component transcriptional regulator  44.25 
 
 
227 aa  181  7e-45  Novosphingobium aromaticivorans DSM 12444  Bacteria  hitchhiker  0.0039171  n/a   
 
 
-
 
NC_007517  Gmet_0528  two component heavy metal response transcriptional regulator  43.44 
 
 
223 aa  181  8.000000000000001e-45  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_1026  two component transcriptional regulator  42.15 
 
 
224 aa  181  9.000000000000001e-45  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.000442073 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  44.59 
 
 
225 aa  180  1e-44  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  42.27 
 
 
222 aa  180  1e-44  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_1091  two component heavy metal response transcriptional regulator  46.9 
 
 
232 aa  181  1e-44  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  44.59 
 
 
225 aa  180  1e-44  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  44.84 
 
 
226 aa  181  1e-44  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_011313  VSAL_II0197  transcriptional activator protein, response regulator  38.94 
 
 
227 aa  180  1e-44  Aliivibrio salmonicida LFI1238  Bacteria  hitchhiker  0.0086442  n/a   
 
 
-
 
NC_010002  Daci_1713  two component heavy metal response transcriptional regulator  44.25 
 
 
227 aa  181  1e-44  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.535279 
 
 
-
 
NC_008825  Mpe_A1629  two-component response regulator  46.02 
 
 
228 aa  180  1e-44  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.128663 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  44.59 
 
 
225 aa  180  1e-44  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  45.33 
 
 
228 aa  180  2e-44  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_012880  Dd703_3722  two component heavy metal response transcriptional regulator, winged helix family  44.34 
 
 
223 aa  180  2e-44  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
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