More than 300 homologs were found in PanDaTox collection
for query gene Athe_0280 on replicon NC_012034
Organism: Anaerocellum thermophilum DSM 6725



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  100 
 
 
225 aa  451  1.0000000000000001e-126  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  63.96 
 
 
240 aa  296  2e-79  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_010184  BcerKBAB4_2944  two component transcriptional regulator  58.74 
 
 
224 aa  276  2e-73  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0958095  n/a   
 
 
-
 
NC_011772  BCG9842_B2033  DNA-binding response regulator  58.04 
 
 
224 aa  276  3e-73  Bacillus cereus G9842  Bacteria  normal  0.725953  normal 
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  57.85 
 
 
224 aa  275  6e-73  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  57.4 
 
 
224 aa  271  5.000000000000001e-72  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_005945  BAS2999  DNA-binding response regulator  56.5 
 
 
224 aa  268  4e-71  Bacillus anthracis str. Sterne  Bacteria  normal  0.227145  n/a   
 
 
-
 
NC_007530  GBAA_3229  DNA-binding response regulator  56.5 
 
 
224 aa  268  4e-71  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  55.86 
 
 
223 aa  265  5e-70  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_4284  two component transcriptional regulator, winged helix family  59.64 
 
 
227 aa  264  1e-69  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  55.61 
 
 
224 aa  255  4e-67  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  58.3 
 
 
224 aa  254  8e-67  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_009767  Rcas_2599  two component transcriptional regulator  58.82 
 
 
232 aa  254  1.0000000000000001e-66  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.268704  normal 
 
 
-
 
NC_011831  Cagg_3502  two component transcriptional regulator, winged helix family  58.82 
 
 
232 aa  254  1.0000000000000001e-66  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_004116  SAG2122  DNA-binding response regulator  55.2 
 
 
223 aa  253  2.0000000000000002e-66  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  54.91 
 
 
224 aa  252  3e-66  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  55.8 
 
 
224 aa  251  9.000000000000001e-66  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  55.8 
 
 
224 aa  250  1e-65  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  54.95 
 
 
223 aa  248  7e-65  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  54.55 
 
 
222 aa  244  9e-64  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  53.81 
 
 
223 aa  242  3.9999999999999997e-63  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  53.39 
 
 
230 aa  239  2e-62  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  52.7 
 
 
223 aa  239  2e-62  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_007517  Gmet_1026  two component transcriptional regulator  48.87 
 
 
224 aa  238  4e-62  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.000442073 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  55.45 
 
 
225 aa  238  5e-62  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  55 
 
 
226 aa  236  1e-61  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  53.85 
 
 
227 aa  236  2e-61  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  51.35 
 
 
225 aa  236  2e-61  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  52.97 
 
 
219 aa  236  3e-61  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  55 
 
 
225 aa  234  7e-61  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  52.94 
 
 
225 aa  234  1.0000000000000001e-60  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_0521  two component transcriptional regulator  50.67 
 
 
223 aa  233  1.0000000000000001e-60  Thermotoga petrophila RKU-1  Bacteria  normal  0.720367  n/a   
 
 
-
 
NC_010730  SYO3AOP1_0130  two component transcriptional regulator, winged helix family  52.02 
 
 
224 aa  234  1.0000000000000001e-60  Sulfurihydrogenibium sp. YO3AOP1  Bacteria  hitchhiker  0.00147609  n/a   
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  49.55 
 
 
224 aa  232  3e-60  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  51.33 
 
 
228 aa  233  3e-60  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_008554  Sfum_2007  two component transcriptional regulator  55.16 
 
 
223 aa  232  4.0000000000000004e-60  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  52.73 
 
 
225 aa  231  6e-60  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  52.73 
 
 
225 aa  231  6e-60  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  50.88 
 
 
226 aa  231  6e-60  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  52.73 
 
 
225 aa  231  6e-60  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  51.12 
 
 
226 aa  230  1e-59  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  53.18 
 
 
225 aa  230  1e-59  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  53.64 
 
 
225 aa  230  1e-59  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_013124  Afer_0703  two component transcriptional regulator, winged helix family  52.02 
 
 
236 aa  229  2e-59  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  50.67 
 
 
226 aa  229  3e-59  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  52.04 
 
 
228 aa  229  3e-59  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_011729  PCC7424_2242  two component transcriptional regulator, winged helix family  52.27 
 
 
224 aa  228  6e-59  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.415885 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  50.22 
 
 
226 aa  228  7e-59  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_008009  Acid345_1658  two component transcriptional regulator  52.02 
 
 
230 aa  228  7e-59  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.450735  normal 
 
 
-
 
NC_009802  CCC13826_1969  response regulator receiver domain-containing protein  51.35 
 
 
219 aa  227  9e-59  Campylobacter concisus 13826  Bacteria  normal  0.478098  n/a   
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  51.58 
 
 
228 aa  227  1e-58  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  50.91 
 
 
226 aa  227  1e-58  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_3411  two component transcriptional regulator, winged helix family  51.82 
 
 
224 aa  227  1e-58  Cyanothece sp. PCC 7425  Bacteria  normal  0.591115  normal 
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  53.18 
 
 
225 aa  227  1e-58  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  50.44 
 
 
228 aa  226  2e-58  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  48.21 
 
 
236 aa  226  3e-58  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  48.88 
 
 
226 aa  226  3e-58  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_013730  Slin_2929  two component transcriptional regulator, winged helix family  48 
 
 
230 aa  226  3e-58  Spirosoma linguale DSM 74  Bacteria  normal  0.0551332  normal 
 
 
-
 
NC_010002  Daci_1713  two component heavy metal response transcriptional regulator  51.11 
 
 
227 aa  225  3e-58  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.535279 
 
 
-
 
NC_007492  Pfl01_3379  two component heavy metal response transcriptional regulator  51.83 
 
 
223 aa  225  4e-58  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_009565  TBFG_11051  two component system transcriptional regulator trcR  49.11 
 
 
257 aa  225  4e-58  Mycobacterium tuberculosis F11  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  52.04 
 
 
232 aa  225  5.0000000000000005e-58  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  50.91 
 
 
223 aa  224  6e-58  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  50.68 
 
 
228 aa  224  9e-58  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  49.77 
 
 
225 aa  223  1e-57  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  48.87 
 
 
225 aa  223  1e-57  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  48.87 
 
 
225 aa  223  1e-57  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  48.87 
 
 
225 aa  223  1e-57  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  50 
 
 
226 aa  224  1e-57  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  51.35 
 
 
225 aa  223  2e-57  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_008025  Dgeo_2318  two component transcriptional regulator  49.77 
 
 
225 aa  223  2e-57  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.642935  normal 
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  48.2 
 
 
223 aa  223  2e-57  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  46.19 
 
 
223 aa  223  2e-57  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_010468  EcolC_3426  DNA-binding transcriptional activator CusR  51.58 
 
 
226 aa  222  3e-57  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  50 
 
 
224 aa  222  4e-57  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  47.75 
 
 
223 aa  222  4e-57  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_007963  Csal_0102  two component heavy metal response transcriptional regulator  51.35 
 
 
223 aa  222  4e-57  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.753235  n/a   
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  48.43 
 
 
225 aa  222  4e-57  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_007912  Sde_1948  response regulator receiver domain-containing protein  48.66 
 
 
226 aa  221  4.9999999999999996e-57  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.679676 
 
 
-
 
NC_013595  Sros_6397  response regulator receiver protein  49.56 
 
 
237 aa  221  4.9999999999999996e-57  Streptosporangium roseum DSM 43021  Bacteria  normal  0.680662  normal  0.0804167 
 
 
-
 
NC_012918  GM21_3531  two component transcriptional regulator, winged helix family  49.55 
 
 
223 aa  221  6e-57  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  50 
 
 
229 aa  221  7e-57  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
CP001637  EcDH1_3058  two component heavy metal response transcriptional regulator, winged helix family  50.23 
 
 
227 aa  221  8e-57  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_3075  DNA-binding transcriptional activator CusR  50.23 
 
 
227 aa  221  8e-57  Escherichia coli ATCC 8739  Bacteria  normal  0.204173  normal 
 
 
-
 
NC_011353  ECH74115_0651  DNA-binding transcriptional activator CusR  50.23 
 
 
227 aa  221  8e-57  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  0.589216  normal 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  49.77 
 
 
228 aa  221  8e-57  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_009800  EcHS_A0618  DNA-binding transcriptional activator CusR  50.23 
 
 
227 aa  221  8e-57  Escherichia coli HS  Bacteria  hitchhiker  0.000374882  n/a   
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  49.77 
 
 
228 aa  221  8e-57  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010498  EcSMS35_0588  DNA-binding transcriptional activator CusR  50.23 
 
 
227 aa  221  8e-57  Escherichia coli SMS-3-5  Bacteria  normal  0.372008  normal 
 
 
-
 
CP001509  ECD_00532  DNA-binding response regulator in two-component regulatory system with CusS  49.77 
 
 
227 aa  220  9.999999999999999e-57  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_0589  DNA-binding transcriptional activator CusR  49.77 
 
 
227 aa  220  9.999999999999999e-57  Escherichia coli E24377A  Bacteria  normal  0.180273  n/a   
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  50.91 
 
 
225 aa  221  9.999999999999999e-57  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_012892  B21_00521  hypothetical protein  49.77 
 
 
227 aa  220  9.999999999999999e-57  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  49.1 
 
 
224 aa  220  9.999999999999999e-57  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  51.58 
 
 
226 aa  220  9.999999999999999e-57  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_2296  two component transcriptional regulator  47.14 
 
 
255 aa  220  9.999999999999999e-57  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.398969  normal  0.240289 
 
 
-
 
NC_013730  Slin_0732  two component transcriptional regulator, winged helix family  47.32 
 
 
231 aa  219  1.9999999999999999e-56  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  48.64 
 
 
224 aa  220  1.9999999999999999e-56  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_009338  Mflv_1887  two component transcriptional regulator  47.35 
 
 
231 aa  219  1.9999999999999999e-56  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.882564  normal  0.344123 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  48.2 
 
 
223 aa  219  1.9999999999999999e-56  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
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