More than 300 homologs were found in PanDaTox collection
for query gene Afer_0703 on replicon NC_013124
Organism: Acidimicrobium ferrooxidans DSM 10331



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013124  Afer_0703  two component transcriptional regulator, winged helix family  100 
 
 
236 aa  480  1e-135  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  60 
 
 
225 aa  281  6.000000000000001e-75  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_013521  Sked_37500  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  60.45 
 
 
225 aa  281  6.000000000000001e-75  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.0213695  normal 
 
 
-
 
NC_013595  Sros_3423  response regulator receiver protein  59.11 
 
 
224 aa  278  6e-74  Streptosporangium roseum DSM 43021  Bacteria  normal  0.699539  normal  0.107362 
 
 
-
 
NC_008699  Noca_1613  response regulator receiver  59.38 
 
 
225 aa  267  8.999999999999999e-71  Nocardioides sp. JS614  Bacteria  normal  0.97266  n/a   
 
 
-
 
NC_013595  Sros_0102  response regulator receiver protein  57.47 
 
 
222 aa  257  1e-67  Streptosporangium roseum DSM 43021  Bacteria  normal  0.294663  normal 
 
 
-
 
NC_008537  Arth_4535  two component transcriptional regulator  56.05 
 
 
227 aa  255  3e-67  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_5468  two component transcriptional regulator, winged helix family  58.11 
 
 
223 aa  254  1.0000000000000001e-66  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_1806  two component transcriptional regulator, winged helix family  55.11 
 
 
225 aa  254  1.0000000000000001e-66  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0205791  normal  0.258829 
 
 
-
 
NC_013441  Gbro_1324  response regulator receiver  56.05 
 
 
223 aa  253  2.0000000000000002e-66  Gordonia bronchialis DSM 43247  Bacteria  normal  0.88989  n/a   
 
 
-
 
NC_008699  Noca_1598  response regulator receiver  55.45 
 
 
226 aa  250  1e-65  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_013165  Shel_13760  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  55.61 
 
 
225 aa  248  6e-65  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_1610  two component transcriptional regulator  52.91 
 
 
232 aa  244  6e-64  Nocardioides sp. JS614  Bacteria  normal  0.496365  n/a   
 
 
-
 
NC_013521  Sked_01690  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  56.11 
 
 
217 aa  244  8e-64  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.459553  normal  0.405302 
 
 
-
 
NC_013947  Snas_4842  two component transcriptional regulator, winged helix family  56.05 
 
 
225 aa  243  3e-63  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.649395  normal 
 
 
-
 
NC_013739  Cwoe_0293  two component transcriptional regulator, winged helix family  50.44 
 
 
226 aa  239  2.9999999999999997e-62  Conexibacter woesei DSM 14684  Bacteria  normal  0.591061  normal  0.658536 
 
 
-
 
NC_014151  Cfla_1294  two component transcriptional regulator, winged helix family  55.45 
 
 
218 aa  234  6e-61  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0476117  hitchhiker  0.00354598 
 
 
-
 
NC_009380  Strop_1594  response regulator receiver  55.45 
 
 
219 aa  231  6e-60  Salinispora tropica CNB-440  Bacteria  normal  0.349405  normal 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  52.02 
 
 
225 aa  229  2e-59  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  50.65 
 
 
283 aa  228  5e-59  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_009953  Sare_1554  two component transcriptional regulator  54.09 
 
 
218 aa  227  2e-58  Salinispora arenicola CNS-205  Bacteria  normal  0.083917  hitchhiker  0.00805861 
 
 
-
 
NC_009565  TBFG_10613  two component system DNA binding transcriptional regulatory protein tcrA  49.56 
 
 
253 aa  225  5.0000000000000005e-58  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.0000000499525  normal  0.750249 
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  50.89 
 
 
240 aa  223  2e-57  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  50 
 
 
224 aa  221  7e-57  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011772  BCG9842_B2033  DNA-binding response regulator  50 
 
 
224 aa  221  8e-57  Bacillus cereus G9842  Bacteria  normal  0.725953  normal 
 
 
-
 
NC_010184  BcerKBAB4_2944  two component transcriptional regulator  50 
 
 
224 aa  220  9.999999999999999e-57  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0958095  n/a   
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  49.78 
 
 
224 aa  220  9.999999999999999e-57  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  50 
 
 
235 aa  219  1.9999999999999999e-56  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_011725  BCB4264_A3221  DNA-binding response regulator  49.55 
 
 
224 aa  220  1.9999999999999999e-56  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS2999  DNA-binding response regulator  49.09 
 
 
224 aa  218  5e-56  Bacillus anthracis str. Sterne  Bacteria  normal  0.227145  n/a   
 
 
-
 
NC_007530  GBAA_3229  DNA-binding response regulator  49.09 
 
 
224 aa  218  5e-56  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  48.88 
 
 
224 aa  216  2e-55  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  48.43 
 
 
224 aa  216  2e-55  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  47.75 
 
 
223 aa  215  4e-55  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  47.09 
 
 
224 aa  213  1.9999999999999998e-54  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  48.43 
 
 
224 aa  212  2.9999999999999995e-54  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  46.67 
 
 
225 aa  211  5.999999999999999e-54  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  49.32 
 
 
225 aa  209  4e-53  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  47.75 
 
 
223 aa  208  6e-53  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  49.32 
 
 
225 aa  207  1e-52  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_010322  PputGB1_4369  two component heavy metal response transcriptional regulator  50 
 
 
224 aa  205  6e-52  Pseudomonas putida GB-1  Bacteria  normal  normal  0.0732935 
 
 
-
 
NC_008148  Rxyl_0187  two component transcriptional regulator  48.91 
 
 
227 aa  204  7e-52  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  49.33 
 
 
225 aa  204  7e-52  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  49.33 
 
 
225 aa  204  9e-52  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_002947  PP_1438  DNA-binding response regulator CzrR  50 
 
 
224 aa  204  1e-51  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_4283  two component heavy metal response transcriptional regulator  50 
 
 
224 aa  204  1e-51  Pseudomonas putida F1  Bacteria  normal  0.0230752  normal 
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  42.6 
 
 
223 aa  204  1e-51  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_010501  PputW619_4391  two component heavy metal response transcriptional regulator  48 
 
 
224 aa  202  3e-51  Pseudomonas putida W619  Bacteria  normal  normal  0.593256 
 
 
-
 
NC_013522  Taci_0717  two component transcriptional regulator, winged helix family  45.7 
 
 
226 aa  202  3e-51  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  hitchhiker  0.000154116  n/a   
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  47.06 
 
 
225 aa  202  4e-51  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_1174  two component heavy metal response transcriptional regulator  48.65 
 
 
224 aa  202  4e-51  Pseudomonas mendocina ymp  Bacteria  normal  0.216853  normal 
 
 
-
 
NC_014158  Tpau_1622  two component transcriptional regulator, winged helix family  48.42 
 
 
223 aa  202  5e-51  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.153936  n/a   
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  50.23 
 
 
225 aa  202  5e-51  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  50.23 
 
 
225 aa  202  5e-51  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  50.23 
 
 
225 aa  202  5e-51  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  47.96 
 
 
226 aa  200  9.999999999999999e-51  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  46.61 
 
 
223 aa  200  9.999999999999999e-51  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  47.56 
 
 
224 aa  200  9.999999999999999e-51  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  47.51 
 
 
226 aa  200  1.9999999999999998e-50  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_013525  Tter_1435  two component transcriptional regulator, winged helix family  48.18 
 
 
233 aa  199  3e-50  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  46.43 
 
 
236 aa  199  3e-50  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  44.8 
 
 
223 aa  199  3e-50  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_4284  two component transcriptional regulator, winged helix family  46.26 
 
 
227 aa  199  3.9999999999999996e-50  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_013124  Afer_0558  two component transcriptional regulator, winged helix family  46.85 
 
 
237 aa  199  3.9999999999999996e-50  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_004578  PSPTO_0378  DNA-binding heavy metal response regulator  46.4 
 
 
224 aa  198  5e-50  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  45.98 
 
 
225 aa  199  5e-50  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_007005  Psyr_4800  heavy metal response regulator  46.4 
 
 
224 aa  198  6e-50  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  hitchhiker  0.00185939 
 
 
-
 
NC_010803  Clim_1291  two component transcriptional regulator, winged helix family  46.4 
 
 
222 aa  198  6e-50  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_45880  putative two-component response regulator  48.88 
 
 
229 aa  198  6e-50  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal  0.954426 
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  45.98 
 
 
224 aa  197  7.999999999999999e-50  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  46.36 
 
 
222 aa  197  7.999999999999999e-50  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_2290  two component transcriptional regulator  46.85 
 
 
224 aa  197  1.0000000000000001e-49  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  47.32 
 
 
225 aa  197  1.0000000000000001e-49  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  47.98 
 
 
226 aa  197  2.0000000000000003e-49  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_013730  Slin_2929  two component transcriptional regulator, winged helix family  44.89 
 
 
230 aa  196  2.0000000000000003e-49  Spirosoma linguale DSM 74  Bacteria  normal  0.0551332  normal 
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  45.5 
 
 
225 aa  197  2.0000000000000003e-49  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  46.85 
 
 
228 aa  196  3e-49  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_007492  Pfl01_3624  two component heavy metal response transcriptional regulator  47.3 
 
 
224 aa  196  3e-49  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  45.13 
 
 
225 aa  196  3e-49  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  46.85 
 
 
229 aa  196  4.0000000000000005e-49  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_010002  Daci_1091  two component heavy metal response transcriptional regulator  46.02 
 
 
232 aa  195  4.0000000000000005e-49  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_3531  two component transcriptional regulator, winged helix family  46.85 
 
 
223 aa  195  4.0000000000000005e-49  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_002947  PP_0047  DNA-binding heavy metal response regulator, putative  45.33 
 
 
224 aa  195  5.000000000000001e-49  Pseudomonas putida KT2440  Bacteria  normal  0.116112  hitchhiker  0.00000494979 
 
 
-
 
NC_010501  PputW619_0064  two component heavy metal response transcriptional regulator  45.33 
 
 
224 aa  195  5.000000000000001e-49  Pseudomonas putida W619  Bacteria  normal  hitchhiker  0.000118539 
 
 
-
 
NC_010322  PputGB1_0061  two component heavy metal response transcriptional regulator  45.33 
 
 
224 aa  195  5.000000000000001e-49  Pseudomonas putida GB-1  Bacteria  normal  normal  0.0868462 
 
 
-
 
NC_009512  Pput_0061  two component heavy metal response transcriptional regulator  45.33 
 
 
224 aa  195  5.000000000000001e-49  Pseudomonas putida F1  Bacteria  normal  0.382659  hitchhiker  0.0034413 
 
 
-
 
NC_009656  PSPA7_2714  putative two-component response regulator  46.85 
 
 
224 aa  195  5.000000000000001e-49  Pseudomonas aeruginosa PA7  Bacteria  normal  0.681326  n/a   
 
 
-
 
NC_008463  PA14_31960  putative two-component response regulator  46.85 
 
 
224 aa  195  5.000000000000001e-49  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.029957  normal 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  47.53 
 
 
226 aa  194  7e-49  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  46.61 
 
 
231 aa  194  7e-49  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  46.4 
 
 
226 aa  194  9e-49  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  46.4 
 
 
225 aa  193  1e-48  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  47.09 
 
 
226 aa  194  1e-48  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  44.14 
 
 
223 aa  194  1e-48  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  46.19 
 
 
228 aa  193  2e-48  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  47.09 
 
 
226 aa  193  2e-48  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_012880  Dd703_3722  two component heavy metal response transcriptional regulator, winged helix family  46.61 
 
 
223 aa  193  2e-48  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  45.95 
 
 
228 aa  193  2e-48  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  44.69 
 
 
225 aa  193  2e-48  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  45.95 
 
 
228 aa  193  2e-48  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
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