More than 300 homologs were found in PanDaTox collection
for query gene Acry_3106 on replicon NC_009467
Organism: Acidiphilium cryptum JF-5



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  100 
 
 
225 aa  447  1e-125  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  69.37 
 
 
223 aa  304  8.000000000000001e-82  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  67.87 
 
 
223 aa  297  7e-80  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0528  two component heavy metal response transcriptional regulator  65.61 
 
 
223 aa  281  7.000000000000001e-75  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  60.71 
 
 
224 aa  275  3e-73  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  61.99 
 
 
226 aa  272  3e-72  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  63.35 
 
 
224 aa  269  2e-71  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  61.26 
 
 
229 aa  269  2e-71  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  61.09 
 
 
226 aa  269  2.9999999999999997e-71  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  59.38 
 
 
224 aa  268  5e-71  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  61.09 
 
 
224 aa  266  1e-70  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  61.99 
 
 
225 aa  267  1e-70  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  63.27 
 
 
225 aa  266  1e-70  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  61.54 
 
 
225 aa  266  2e-70  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  61.54 
 
 
225 aa  266  2e-70  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  60.36 
 
 
224 aa  266  2e-70  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  62.39 
 
 
225 aa  264  7e-70  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  62.16 
 
 
225 aa  261  4e-69  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  62.16 
 
 
225 aa  261  4e-69  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  62.16 
 
 
225 aa  261  4e-69  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  58.67 
 
 
224 aa  261  6e-69  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  61.09 
 
 
226 aa  260  1e-68  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  60.27 
 
 
228 aa  260  1e-68  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  59.64 
 
 
226 aa  259  2e-68  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  59.73 
 
 
223 aa  259  2e-68  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  60.27 
 
 
228 aa  259  2e-68  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  57.66 
 
 
223 aa  259  2e-68  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_008835  BMA10229_0402  transcriptional activator IrlR  61.09 
 
 
229 aa  259  3e-68  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0800763  n/a   
 
 
-
 
NC_006349  BMAA1028  DNA-binding response regulator IrlR  61.09 
 
 
229 aa  259  3e-68  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0282692  n/a   
 
 
-
 
NC_009079  BMA10247_A1180  transcriptional activator IrlR  61.09 
 
 
229 aa  259  3e-68  Burkholderia mallei NCTC 10247  Bacteria  normal  0.0831411  n/a   
 
 
-
 
NC_007435  BURPS1710b_A0030  DNA-binding response regulator IrlR  61.09 
 
 
229 aa  259  3e-68  Burkholderia pseudomallei 1710b  Bacteria  normal  0.122488  n/a   
 
 
-
 
NC_009075  BURPS668_A1524  transcriptional activator protein IrlR  61.09 
 
 
229 aa  259  3e-68  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1439  transcriptional activator IrlR  61.09 
 
 
229 aa  259  3e-68  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_008784  BMASAVP1_0010  transcriptional activator IrlR  61.09 
 
 
229 aa  259  3e-68  Burkholderia mallei SAVP1  Bacteria  normal  0.121051  n/a   
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  59.64 
 
 
226 aa  258  4e-68  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5873  two component heavy metal response transcriptional regulator, winged helix family  58.37 
 
 
228 aa  258  5.0000000000000005e-68  Burkholderia phytofirmans PsJN  Bacteria  normal  0.247228  normal 
 
 
-
 
NC_007650  BTH_II1376  DNA-binding response regulator IrlR  60.63 
 
 
229 aa  258  5.0000000000000005e-68  Burkholderia thailandensis E264  Bacteria  normal  0.498923  n/a   
 
 
-
 
NC_007952  Bxe_B2069  two component heavy metal response transcriptional regulator  58.37 
 
 
228 aa  258  5.0000000000000005e-68  Burkholderia xenovorans LB400  Bacteria  normal  0.0102482  normal 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  60.36 
 
 
230 aa  258  5.0000000000000005e-68  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  59.64 
 
 
226 aa  258  6e-68  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  57.21 
 
 
225 aa  258  6e-68  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  58.74 
 
 
228 aa  258  7e-68  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  60.27 
 
 
228 aa  258  7e-68  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  56.76 
 
 
223 aa  258  7e-68  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  57.4 
 
 
226 aa  257  1e-67  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_007974  Rmet_4465  two component heavy metal response transcriptional regulator, winged helix family  63.11 
 
 
206 aa  257  1e-67  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0436659 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  58.56 
 
 
228 aa  256  2e-67  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_010501  PputW619_4391  two component heavy metal response transcriptional regulator  57.33 
 
 
224 aa  256  2e-67  Pseudomonas putida W619  Bacteria  normal  normal  0.593256 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  60.63 
 
 
226 aa  256  2e-67  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  57.21 
 
 
223 aa  256  2e-67  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_004578  PSPTO_1307  DNA-binding heavy metal response regulator  59.91 
 
 
225 aa  256  3e-67  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.150056  n/a   
 
 
-
 
NC_011662  Tmz1t_2101  two component heavy metal response transcriptional regulator, winged helix family  60.18 
 
 
228 aa  256  3e-67  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  59.91 
 
 
225 aa  256  3e-67  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  61.26 
 
 
242 aa  255  3e-67  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_011667  Tmz1t_2388  heavy metal response regulator  60.18 
 
 
228 aa  256  3e-67  Thauera sp. MZ1T  Bacteria  decreased coverage  0.000142984  normal  0.119734 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  58.74 
 
 
226 aa  256  3e-67  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_3465  two component transcriptional regulator, winged helix family  57.21 
 
 
223 aa  255  4e-67  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  60.36 
 
 
227 aa  255  4e-67  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  57.47 
 
 
225 aa  255  5e-67  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_010681  Bphyt_1510  two component heavy metal response transcriptional regulator, winged helix family  59.38 
 
 
227 aa  254  6e-67  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_1091  two component heavy metal response transcriptional regulator  60.62 
 
 
232 aa  254  6e-67  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  56.76 
 
 
223 aa  254  7e-67  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  56.76 
 
 
223 aa  254  7e-67  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  60.73 
 
 
219 aa  254  9e-67  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_010625  Bphy_6519  two component heavy metal response transcriptional regulator  57.47 
 
 
228 aa  253  1.0000000000000001e-66  Burkholderia phymatum STM815  Bacteria  normal  normal  0.0435386 
 
 
-
 
NC_012918  GM21_3531  two component transcriptional regulator, winged helix family  56.76 
 
 
223 aa  254  1.0000000000000001e-66  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_009439  Pmen_1174  two component heavy metal response transcriptional regulator  57.66 
 
 
224 aa  253  1.0000000000000001e-66  Pseudomonas mendocina ymp  Bacteria  normal  0.216853  normal 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  58.56 
 
 
228 aa  253  2.0000000000000002e-66  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_007005  Psyr_1127  heavy metal response regulator  59.01 
 
 
225 aa  253  2.0000000000000002e-66  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.294376  normal  0.216529 
 
 
-
 
NC_007951  Bxe_A2960  two component heavy metal response transcriptional regulator  59.91 
 
 
227 aa  253  2.0000000000000002e-66  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  58.56 
 
 
228 aa  253  2.0000000000000002e-66  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  57.47 
 
 
225 aa  253  2.0000000000000002e-66  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_008782  Ajs_2725  two component heavy metal response transcriptional regulator  59.01 
 
 
227 aa  252  3e-66  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  58.04 
 
 
225 aa  252  4.0000000000000004e-66  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_010070  Bmul_6295  two component heavy metal response transcriptional regulator  55.41 
 
 
223 aa  251  5.000000000000001e-66  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.803537  normal  0.219108 
 
 
-
 
NC_007511  Bcep18194_B2768  two component heavy metal response transcriptional regulator  56.31 
 
 
223 aa  251  5.000000000000001e-66  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_008825  Mpe_A1629  two-component response regulator  57.96 
 
 
228 aa  251  5.000000000000001e-66  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.128663 
 
 
-
 
NC_011992  Dtpsy_2201  two component heavy metal response transcriptional regulator, winged helix family  59.01 
 
 
227 aa  251  5.000000000000001e-66  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  56.56 
 
 
231 aa  251  7e-66  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_0064  two component heavy metal response transcriptional regulator  55.41 
 
 
224 aa  250  1e-65  Pseudomonas putida W619  Bacteria  normal  hitchhiker  0.000118539 
 
 
-
 
NC_002947  PP_0047  DNA-binding heavy metal response regulator, putative  55.41 
 
 
224 aa  250  1e-65  Pseudomonas putida KT2440  Bacteria  normal  0.116112  hitchhiker  0.00000494979 
 
 
-
 
NC_010322  PputGB1_0061  two component heavy metal response transcriptional regulator  55.41 
 
 
224 aa  250  1e-65  Pseudomonas putida GB-1  Bacteria  normal  normal  0.0868462 
 
 
-
 
NC_009512  Pput_0061  two component heavy metal response transcriptional regulator  55.41 
 
 
224 aa  250  1e-65  Pseudomonas putida F1  Bacteria  normal  0.382659  hitchhiker  0.0034413 
 
 
-
 
NC_010515  Bcenmc03_3842  two component heavy metal response transcriptional regulator  57.33 
 
 
227 aa  250  1e-65  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.67414 
 
 
-
 
NC_008061  Bcen_4683  two component heavy metal response transcriptional regulator  57.33 
 
 
228 aa  250  1e-65  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.222547  n/a   
 
 
-
 
NC_008543  Bcen2424_3680  two component heavy metal response transcriptional regulator  57.33 
 
 
228 aa  250  1e-65  Burkholderia cenocepacia HI2424  Bacteria  normal  0.224842  normal 
 
 
-
 
NC_010676  Bphyt_4389  two component heavy metal response transcriptional regulator, winged helix family  56.89 
 
 
226 aa  249  2e-65  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B0708  two component heavy metal response transcriptional regulator  58.37 
 
 
226 aa  249  3e-65  Burkholderia xenovorans LB400  Bacteria  normal  0.328024  normal  0.9016 
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  59.46 
 
 
227 aa  249  3e-65  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_1438  DNA-binding response regulator CzrR  56.31 
 
 
224 aa  248  4e-65  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_010070  Bmul_6173  two component heavy metal response transcriptional regulator  57.33 
 
 
228 aa  248  4e-65  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.400074 
 
 
-
 
NC_009512  Pput_4283  two component heavy metal response transcriptional regulator  56.31 
 
 
224 aa  248  4e-65  Pseudomonas putida F1  Bacteria  normal  0.0230752  normal 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  56.31 
 
 
225 aa  248  5e-65  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  56.31 
 
 
225 aa  248  5e-65  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  56.31 
 
 
225 aa  248  5e-65  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_007511  Bcep18194_B2430  two component heavy metal response transcriptional regulator  56.89 
 
 
227 aa  248  6e-65  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  53.15 
 
 
223 aa  247  9e-65  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_004578  PSPTO_0378  DNA-binding heavy metal response regulator  54.95 
 
 
224 aa  246  1e-64  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_4800  heavy metal response regulator  54.95 
 
 
224 aa  247  1e-64  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  hitchhiker  0.00185939 
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  56.31 
 
 
225 aa  247  1e-64  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
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