More than 300 homologs were found in PanDaTox collection
for query gene Daci_0451 on replicon NC_010002
Organism: Delftia acidovorans SPH-1



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  100 
 
 
230 aa  455  1e-127  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  94.71 
 
 
227 aa  431  1e-120  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  97.72 
 
 
219 aa  424  1e-118  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  80.97 
 
 
228 aa  368  1e-101  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_007912  Sde_1948  response regulator receiver domain-containing protein  79.2 
 
 
226 aa  368  1e-101  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.679676 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  80.97 
 
 
228 aa  369  1e-101  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  81.42 
 
 
228 aa  362  3e-99  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  80.97 
 
 
228 aa  362  3e-99  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  80.97 
 
 
228 aa  362  3e-99  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  80.09 
 
 
228 aa  358  3e-98  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_007347  Reut_A2490  heavy metal response regulator  82.3 
 
 
228 aa  353  2e-96  Ralstonia eutropha JMP134  Bacteria  normal  0.289616  n/a   
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  75.11 
 
 
225 aa  347  1e-94  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007971  Rmet_6111  regulator protein CopR  79.39 
 
 
228 aa  342  2.9999999999999997e-93  Cupriavidus metallidurans CH34  Bacteria  normal  0.110686  normal  0.158568 
 
 
-
 
NC_007974  Rmet_5672  DNA-binding response regulator  80.53 
 
 
228 aa  342  2.9999999999999997e-93  Cupriavidus metallidurans CH34  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1742  two component heavy metal response transcriptional regulator, winged helix family  81.33 
 
 
228 aa  341  5.999999999999999e-93  Ralstonia pickettii 12J  Bacteria  normal  normal  0.595604 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  74.44 
 
 
226 aa  333  1e-90  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  73.99 
 
 
226 aa  332  2e-90  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  74.11 
 
 
227 aa  331  4e-90  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  73.8 
 
 
232 aa  331  5e-90  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
CP001637  EcDH1_3058  two component heavy metal response transcriptional regulator, winged helix family  70.22 
 
 
227 aa  328  4e-89  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_3075  DNA-binding transcriptional activator CusR  70.22 
 
 
227 aa  328  4e-89  Escherichia coli ATCC 8739  Bacteria  normal  0.204173  normal 
 
 
-
 
NC_010498  EcSMS35_0588  DNA-binding transcriptional activator CusR  70.22 
 
 
227 aa  328  4e-89  Escherichia coli SMS-3-5  Bacteria  normal  0.372008  normal 
 
 
-
 
NC_011353  ECH74115_0651  DNA-binding transcriptional activator CusR  70.22 
 
 
227 aa  328  4e-89  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  0.589216  normal 
 
 
-
 
NC_009800  EcHS_A0618  DNA-binding transcriptional activator CusR  70.22 
 
 
227 aa  328  4e-89  Escherichia coli HS  Bacteria  hitchhiker  0.000374882  n/a   
 
 
-
 
NC_011138  MADE_00315  probable two component response regulator transcription regulator protein  70.93 
 
 
227 aa  328  5.0000000000000004e-89  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
CP001509  ECD_00532  DNA-binding response regulator in two-component regulatory system with CusS  69.78 
 
 
227 aa  327  1.0000000000000001e-88  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_0589  DNA-binding transcriptional activator CusR  69.78 
 
 
227 aa  327  1.0000000000000001e-88  Escherichia coli E24377A  Bacteria  normal  0.180273  n/a   
 
 
-
 
NC_012892  B21_00521  hypothetical protein  69.78 
 
 
227 aa  327  1.0000000000000001e-88  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  70.67 
 
 
225 aa  325  3e-88  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  71.11 
 
 
225 aa  323  2e-87  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  71.11 
 
 
225 aa  323  2e-87  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  71.11 
 
 
225 aa  323  2e-87  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  70.72 
 
 
223 aa  322  3e-87  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  71.56 
 
 
225 aa  322  4e-87  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_010468  EcolC_3426  DNA-binding transcriptional activator CusR  68.44 
 
 
226 aa  318  6e-86  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_009438  Sputcn32_0258  DNA-binding transcriptional activator CusR  68 
 
 
226 aa  316  2e-85  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  71.05 
 
 
228 aa  315  4e-85  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_008573  Shewana3_4296  DNA-binding transcriptional activator CusR  67.56 
 
 
226 aa  315  5e-85  Shewanella sp. ANA-3  Bacteria  decreased coverage  0.0000252174  normal 
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  72 
 
 
226 aa  314  7e-85  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  69.91 
 
 
226 aa  314  8e-85  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  69.47 
 
 
228 aa  312  2.9999999999999996e-84  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  68.14 
 
 
226 aa  310  1e-83  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  69.82 
 
 
226 aa  309  2e-83  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  69.82 
 
 
226 aa  308  4e-83  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  70.35 
 
 
227 aa  308  5e-83  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  69.82 
 
 
226 aa  308  5.9999999999999995e-83  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_009092  Shew_3258  two component heavy metal response transcriptional regulator  63.68 
 
 
238 aa  308  5.9999999999999995e-83  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00206307  normal  0.0675777 
 
 
-
 
NC_010501  PputW619_1675  two component heavy metal response transcriptional regulator  70.35 
 
 
226 aa  304  6e-82  Pseudomonas putida W619  Bacteria  normal  0.294903  normal 
 
 
-
 
NC_009439  Pmen_2234  two component heavy metal response transcriptional regulator  69.78 
 
 
225 aa  302  2.0000000000000002e-81  Pseudomonas mendocina ymp  Bacteria  normal  0.162422  normal 
 
 
-
 
NC_007404  Tbd_1749  two component heavy metal response transcriptional regulator  69.87 
 
 
242 aa  298  5e-80  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_011992  Dtpsy_2201  two component heavy metal response transcriptional regulator, winged helix family  68.14 
 
 
227 aa  295  3e-79  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  63.27 
 
 
226 aa  295  4e-79  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_2725  two component heavy metal response transcriptional regulator  68.14 
 
 
227 aa  295  5e-79  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  67.12 
 
 
224 aa  294  6e-79  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  65.92 
 
 
224 aa  293  1e-78  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_007511  Bcep18194_B2430  two component heavy metal response transcriptional regulator  65.47 
 
 
227 aa  291  5e-78  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_008061  Bcen_4683  two component heavy metal response transcriptional regulator  65.47 
 
 
228 aa  291  6e-78  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.222547  n/a   
 
 
-
 
NC_008543  Bcen2424_3680  two component heavy metal response transcriptional regulator  65.47 
 
 
228 aa  291  6e-78  Burkholderia cenocepacia HI2424  Bacteria  normal  0.224842  normal 
 
 
-
 
NC_010515  Bcenmc03_3842  two component heavy metal response transcriptional regulator  65.47 
 
 
227 aa  291  8e-78  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.67414 
 
 
-
 
NC_010681  Bphyt_1510  two component heavy metal response transcriptional regulator, winged helix family  65.32 
 
 
227 aa  289  2e-77  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_010070  Bmul_6173  two component heavy metal response transcriptional regulator  65.02 
 
 
228 aa  290  2e-77  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.400074 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  65.33 
 
 
225 aa  288  5.0000000000000004e-77  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  65.77 
 
 
229 aa  287  1e-76  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  64.89 
 
 
225 aa  287  1e-76  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  64.89 
 
 
225 aa  287  1e-76  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_007951  Bxe_A2960  two component heavy metal response transcriptional regulator  63.96 
 
 
227 aa  286  2e-76  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  64.41 
 
 
224 aa  286  2e-76  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_007650  BTH_II0376  DNA-binding response regulator IrlR  64.86 
 
 
230 aa  285  2.9999999999999996e-76  Burkholderia thailandensis E264  Bacteria  normal  0.083776  n/a   
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  65.33 
 
 
225 aa  285  2.9999999999999996e-76  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_007435  BURPS1710b_A1103  DNA-binding response regulator IrlR  64.86 
 
 
230 aa  285  4e-76  Burkholderia pseudomallei 1710b  Bacteria  normal  0.0630149  n/a   
 
 
-
 
NC_009075  BURPS668_A2869  transcriptional activator protein IrlR  64.86 
 
 
230 aa  285  4e-76  Burkholderia pseudomallei 668  Bacteria  normal  0.354021  n/a   
 
 
-
 
NC_009078  BURPS1106A_A2716  DNA-binding heavy metal response regulator  64.86 
 
 
230 aa  285  4e-76  Burkholderia pseudomallei 1106a  Bacteria  normal  0.558922  n/a   
 
 
-
 
NC_007952  Bxe_B1748a  hypothetical protein  63.35 
 
 
223 aa  284  8e-76  Burkholderia xenovorans LB400  Bacteria  normal  0.0697031  normal  0.305387 
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  64.6 
 
 
225 aa  284  8e-76  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  64.6 
 
 
225 aa  284  8e-76  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  64.6 
 
 
225 aa  284  8e-76  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_009075  BURPS668_A1524  transcriptional activator protein IrlR  64.41 
 
 
229 aa  284  9e-76  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_006349  BMAA1028  DNA-binding response regulator IrlR  64.41 
 
 
229 aa  284  9e-76  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0282692  n/a   
 
 
-
 
NC_007435  BURPS1710b_A0030  DNA-binding response regulator IrlR  64.41 
 
 
229 aa  284  9e-76  Burkholderia pseudomallei 1710b  Bacteria  normal  0.122488  n/a   
 
 
-
 
NC_009079  BMA10247_A1180  transcriptional activator IrlR  64.41 
 
 
229 aa  284  9e-76  Burkholderia mallei NCTC 10247  Bacteria  normal  0.0831411  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1439  transcriptional activator IrlR  64.41 
 
 
229 aa  284  9e-76  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_0402  transcriptional activator IrlR  64.41 
 
 
229 aa  284  9e-76  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0800763  n/a   
 
 
-
 
NC_008784  BMASAVP1_0010  transcriptional activator IrlR  64.41 
 
 
229 aa  284  9e-76  Burkholderia mallei SAVP1  Bacteria  normal  0.121051  n/a   
 
 
-
 
NC_010676  Bphyt_4389  two component heavy metal response transcriptional regulator, winged helix family  64.86 
 
 
226 aa  283  1.0000000000000001e-75  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  62.61 
 
 
223 aa  284  1.0000000000000001e-75  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_007963  Csal_0102  two component heavy metal response transcriptional regulator  64.41 
 
 
223 aa  283  2.0000000000000002e-75  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.753235  n/a   
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  62.61 
 
 
223 aa  283  2.0000000000000002e-75  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B0708  two component heavy metal response transcriptional regulator  63.96 
 
 
226 aa  282  3.0000000000000004e-75  Burkholderia xenovorans LB400  Bacteria  normal  0.328024  normal  0.9016 
 
 
-
 
NC_010676  Bphyt_4933  two component heavy metal response transcriptional regulator, winged helix family  62.9 
 
 
223 aa  281  5.000000000000001e-75  Burkholderia phytofirmans PsJN  Bacteria  normal  0.461594  normal  0.344735 
 
 
-
 
NC_007650  BTH_II1376  DNA-binding response regulator IrlR  63.51 
 
 
229 aa  281  6.000000000000001e-75  Burkholderia thailandensis E264  Bacteria  normal  0.498923  n/a   
 
 
-
 
NC_010002  Daci_1091  two component heavy metal response transcriptional regulator  62.56 
 
 
232 aa  281  8.000000000000001e-75  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_1174  two component heavy metal response transcriptional regulator  61.88 
 
 
224 aa  280  1e-74  Pseudomonas mendocina ymp  Bacteria  normal  0.216853  normal 
 
 
-
 
NC_007953  Bxe_C1381  two component heavy metal response transcriptional regulator  59.91 
 
 
224 aa  280  1e-74  Burkholderia xenovorans LB400  Bacteria  normal  normal  0.961918 
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  56.33 
 
 
230 aa  279  2e-74  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_010468  EcolC_3412  two component heavy metal response transcriptional regulator  61.06 
 
 
226 aa  279  3e-74  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  62.33 
 
 
223 aa  279  3e-74  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  60.99 
 
 
223 aa  278  4e-74  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009524  PsycPRwf_0705  two component heavy metal response transcriptional regulator  58.74 
 
 
244 aa  278  5e-74  Psychrobacter sp. PRwf-1  Bacteria  normal  normal  0.591946 
 
 
-
 
NC_002947  PP_1438  DNA-binding response regulator CzrR  62.33 
 
 
224 aa  277  8e-74  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_4283  two component heavy metal response transcriptional regulator  62.33 
 
 
224 aa  277  8e-74  Pseudomonas putida F1  Bacteria  normal  0.0230752  normal 
 
 
-
 
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