More than 300 homologs were found in PanDaTox collection
for query gene MCA2330 on replicon NC_002977
Organism: Methylococcus capsulatus str. Bath



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_002977  MCA2330  DNA-binding response regulator  100 
 
 
228 aa  451  1.0000000000000001e-126  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_007974  Rmet_5331  transcriptional regulator two components regulatory system  65.61 
 
 
225 aa  293  2e-78  Cupriavidus metallidurans CH34  Bacteria  normal  0.0274603  normal 
 
 
-
 
NC_003296  RS02379  two-component response regulator transcription regulator protein  68.47 
 
 
227 aa  272  3e-72  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.261012 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  49.55 
 
 
224 aa  226  3e-58  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  50.45 
 
 
224 aa  223  2e-57  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  50.45 
 
 
224 aa  222  3e-57  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  50 
 
 
224 aa  220  1.9999999999999999e-56  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010814  Glov_0998  two component transcriptional regulator, winged helix family  51.8 
 
 
223 aa  219  3.9999999999999997e-56  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_009467  Acry_3106  two component heavy metal response transcriptional regulator  50.91 
 
 
225 aa  218  5e-56  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  49.55 
 
 
224 aa  216  2e-55  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  49.55 
 
 
223 aa  215  4e-55  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  51.8 
 
 
223 aa  214  5.9999999999999996e-55  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  48.66 
 
 
222 aa  213  9.999999999999999e-55  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  51.36 
 
 
240 aa  211  9e-54  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  47.73 
 
 
225 aa  210  1e-53  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  50.45 
 
 
223 aa  209  2e-53  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_011831  Cagg_3502  two component transcriptional regulator, winged helix family  53.39 
 
 
232 aa  207  2e-52  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  48.64 
 
 
283 aa  206  2e-52  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_009767  Rcas_2599  two component transcriptional regulator  53.39 
 
 
232 aa  207  2e-52  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.268704  normal 
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  50.91 
 
 
223 aa  206  3e-52  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_013093  Amir_5468  two component transcriptional regulator, winged helix family  48.64 
 
 
223 aa  206  3e-52  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  47.73 
 
 
235 aa  205  5e-52  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  50.45 
 
 
224 aa  204  7e-52  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  50 
 
 
226 aa  204  7e-52  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_011365  Gdia_2950  two component transcriptional regulator, winged helix family  48.86 
 
 
258 aa  204  8e-52  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  0.0307025  normal  0.153934 
 
 
-
 
NC_013165  Shel_13760  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  48.18 
 
 
225 aa  203  2e-51  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_3423  response regulator receiver protein  47.75 
 
 
224 aa  201  5e-51  Streptosporangium roseum DSM 43021  Bacteria  normal  0.699539  normal  0.107362 
 
 
-
 
NC_007517  Gmet_0528  two component heavy metal response transcriptional regulator  50.67 
 
 
223 aa  201  6e-51  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  50.89 
 
 
226 aa  201  9e-51  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  50.67 
 
 
225 aa  201  9.999999999999999e-51  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  43.24 
 
 
224 aa  200  9.999999999999999e-51  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  47.3 
 
 
225 aa  200  1.9999999999999998e-50  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_010002  Daci_1091  two component heavy metal response transcriptional regulator  51.11 
 
 
232 aa  200  1.9999999999999998e-50  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  50.89 
 
 
226 aa  200  1.9999999999999998e-50  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  49.09 
 
 
223 aa  199  3e-50  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_004578  PSPTO_3603  DNA-binding heavy metal response regulator  50.46 
 
 
229 aa  198  7e-50  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.203952  n/a   
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  48.46 
 
 
230 aa  198  7e-50  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  47.58 
 
 
227 aa  198  7e-50  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_009439  Pmen_1174  two component heavy metal response transcriptional regulator  49.78 
 
 
224 aa  197  1.0000000000000001e-49  Pseudomonas mendocina ymp  Bacteria  normal  0.216853  normal 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  48.64 
 
 
224 aa  197  1.0000000000000001e-49  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  47.32 
 
 
230 aa  197  1.0000000000000001e-49  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  48.64 
 
 
224 aa  196  2.0000000000000003e-49  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_1613  response regulator receiver  45 
 
 
225 aa  197  2.0000000000000003e-49  Nocardioides sp. JS614  Bacteria  normal  0.97266  n/a   
 
 
-
 
NC_007005  Psyr_3374  heavy metal response regulator  50.46 
 
 
229 aa  196  3e-49  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  49.33 
 
 
228 aa  196  3e-49  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  49.12 
 
 
226 aa  196  4.0000000000000005e-49  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_1438  DNA-binding response regulator CzrR  48.43 
 
 
224 aa  195  6e-49  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_4283  two component heavy metal response transcriptional regulator  48.43 
 
 
224 aa  195  6e-49  Pseudomonas putida F1  Bacteria  normal  0.0230752  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  48.67 
 
 
228 aa  195  6e-49  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  48.88 
 
 
228 aa  194  7e-49  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  48.88 
 
 
228 aa  194  7e-49  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_009719  Plav_0944  two component transcriptional regulator  46.9 
 
 
225 aa  194  8.000000000000001e-49  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.091613  normal 
 
 
-
 
NC_008825  Mpe_A1629  two-component response regulator  48.66 
 
 
228 aa  194  1e-48  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.128663 
 
 
-
 
NC_013595  Sros_0102  response regulator receiver protein  47.27 
 
 
222 aa  194  1e-48  Streptosporangium roseum DSM 43021  Bacteria  normal  0.294663  normal 
 
 
-
 
NC_009654  Mmwyl1_0419  two component transcriptional regulator  45.54 
 
 
229 aa  194  1e-48  Marinomonas sp. MWYL1  Bacteria  normal  0.509677  normal 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  48.87 
 
 
228 aa  193  2e-48  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_009664  Krad_1806  two component transcriptional regulator, winged helix family  46.85 
 
 
225 aa  193  2e-48  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0205791  normal  0.258829 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  50 
 
 
229 aa  193  2e-48  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_010322  PputGB1_4369  two component heavy metal response transcriptional regulator  48.43 
 
 
224 aa  192  3e-48  Pseudomonas putida GB-1  Bacteria  normal  normal  0.0732935 
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  48.86 
 
 
219 aa  192  4e-48  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  48 
 
 
225 aa  192  4e-48  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_008009  Acid345_1658  two component transcriptional regulator  49.09 
 
 
230 aa  192  4e-48  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.450735  normal 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  48.42 
 
 
228 aa  191  6e-48  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_007492  Pfl01_3624  two component heavy metal response transcriptional regulator  49.78 
 
 
224 aa  191  7e-48  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  48.65 
 
 
226 aa  191  8e-48  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  45 
 
 
223 aa  191  9e-48  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_010681  Bphyt_1510  two component heavy metal response transcriptional regulator, winged helix family  47.37 
 
 
227 aa  191  1e-47  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_1598  response regulator receiver  44.09 
 
 
226 aa  191  1e-47  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  49.78 
 
 
227 aa  191  1e-47  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_007952  Bxe_B1748a  hypothetical protein  46.61 
 
 
223 aa  190  1e-47  Burkholderia xenovorans LB400  Bacteria  normal  0.0697031  normal  0.305387 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  48.88 
 
 
228 aa  190  2e-47  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  45.5 
 
 
225 aa  190  2e-47  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_007575  Suden_0317  two component transcriptional regulator  41.52 
 
 
224 aa  190  2e-47  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  47.56 
 
 
225 aa  189  2e-47  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  45.91 
 
 
224 aa  189  2e-47  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  47.73 
 
 
225 aa  189  2.9999999999999997e-47  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_011138  MADE_00315  probable two component response regulator transcription regulator protein  45.58 
 
 
227 aa  189  2.9999999999999997e-47  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_009720  Xaut_3517  two component transcriptional regulator  48.21 
 
 
238 aa  189  2.9999999999999997e-47  Xanthobacter autotrophicus Py2  Bacteria  normal  0.0423488  normal  0.321822 
 
 
-
 
NC_010676  Bphyt_4933  two component heavy metal response transcriptional regulator, winged helix family  46.61 
 
 
223 aa  189  2.9999999999999997e-47  Burkholderia phytofirmans PsJN  Bacteria  normal  0.461594  normal  0.344735 
 
 
-
 
NC_010002  Daci_1713  two component heavy metal response transcriptional regulator  46.22 
 
 
227 aa  189  2.9999999999999997e-47  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.535279 
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  48.18 
 
 
224 aa  189  4e-47  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  47.73 
 
 
225 aa  189  4e-47  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  47.51 
 
 
226 aa  188  5.999999999999999e-47  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_011729  PCC7424_4284  two component transcriptional regulator, winged helix family  44.05 
 
 
227 aa  188  5.999999999999999e-47  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  47.96 
 
 
226 aa  188  5.999999999999999e-47  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_009484  Acry_0450  two component transcriptional regulator  48.2 
 
 
227 aa  188  5.999999999999999e-47  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_008537  Arth_4535  two component transcriptional regulator  45.5 
 
 
227 aa  188  5.999999999999999e-47  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_3235  DNA-binding response regulator  43.44 
 
 
224 aa  188  7e-47  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_007951  Bxe_A2960  two component heavy metal response transcriptional regulator  48.64 
 
 
227 aa  188  7e-47  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_007963  Csal_0102  two component heavy metal response transcriptional regulator  50.91 
 
 
223 aa  188  7e-47  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.753235  n/a   
 
 
-
 
NC_010831  Cphamn1_0990  two component transcriptional regulator, winged helix family  43.18 
 
 
222 aa  188  7e-47  Chlorobium phaeobacteroides BS1  Bacteria  hitchhiker  0.000957791  decreased coverage  0.0000715536 
 
 
-
 
NC_011146  Gbem_3465  two component transcriptional regulator, winged helix family  47.27 
 
 
223 aa  187  1e-46  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_0293  two component transcriptional regulator, winged helix family  46.85 
 
 
226 aa  187  1e-46  Conexibacter woesei DSM 14684  Bacteria  normal  0.591061  normal  0.658536 
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  46.02 
 
 
228 aa  187  1e-46  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  47.51 
 
 
226 aa  187  1e-46  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010658  SbBS512_E0914  transcriptional regulatory protein YedW  46.19 
 
 
260 aa  187  1e-46  Shigella boydii CDC 3083-94  Bacteria  decreased coverage  0.0000000013212  n/a   
 
 
-
 
NC_013521  Sked_37500  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  44.39 
 
 
225 aa  187  1e-46  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.0213695  normal 
 
 
-
 
NC_008463  PA14_45880  putative two-component response regulator  47.06 
 
 
229 aa  187  1e-46  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal  0.954426 
 
 
-
 
CP001637  EcDH1_1682  two component heavy metal response transcriptional regulator, winged helix family  46.19 
 
 
260 aa  186  2e-46  Escherichia coli DH1  Bacteria  decreased coverage  0.000000000000361446  n/a   
 
 
-
 
NC_009511  Swit_4798  two component transcriptional regulator  46.88 
 
 
230 aa  186  2e-46  Sphingomonas wittichii RW1  Bacteria  normal  normal  0.358461 
 
 
-
 
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