More than 300 homologs were found in PanDaTox collection
for query gene SNSL254_A1504 on replicon NC_011080
Organism: Salmonella enterica subsp. enterica serovar Newport str. SL254



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_011080  SNSL254_A1504  hypothetical protein  100 
 
 		 212 aa  436  1e-121  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  1  hitchhiker  0.000000918459 
 
 
-
 
NC_011205  SeD_A1950  hypothetical protein  99.53 
 
 		 212 aa  433  1e-120  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  1  hitchhiker  0.0094858 
 
 
-
 
NC_011083  SeHA_C1526  two-component response regulator EsrB  99.53 
 
 		 212 aa  433  1e-120  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  0.577557  hitchhiker  0.00169027 
 
 
-
 
NC_011149  SeAg_B1780  EsrB  99.06 
 
 		 212 aa  431  1e-120  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  0.111024  n/a   
 
 
-
 
NC_011094  SeSA_A1489  EsrB  99.53 
 
 		 212 aa  433  1e-120  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.121116  normal  0.320198 
 
 
-
 
NC_009708  YpsIP31758_3833  putative DNA-binding response regulator EsrB  54.15 
 
 		 210 aa  221  7e-57  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  1  n/a   
 
 
-
 
NC_010465  YPK_3919  two component LuxR family transcriptional regulator  54.15 
 
 		 210 aa  221  7e-57  Yersinia pseudotuberculosis YPIII  Bacteria  normal  1  n/a   
 
 
-
 
NC_010159  YpAngola_A3945  putative DNA-binding response regulator EsrB  53.66 
 
 		 210 aa  219  1.9999999999999999e-56  Yersinia pestis Angola  Bacteria  normal  0.0480381  normal  1 
 
 
-
 
NC_009052  Sbal_1943  two component LuxR family transcriptional regulator  46.63 
 
 		 214 aa  192  2e-48  Shewanella baltica OS155  Bacteria  normal  1  n/a   
 
 
-
 
NC_009997  Sbal195_2246  two component LuxR family transcriptional regulator  46.63 
 
 		 214 aa  192  3e-48  Shewanella baltica OS195  Bacteria  normal  0.0703025  hitchhiker  0.00413313 
 
 
-
 
NC_008554  Sfum_1664  two component LuxR family transcriptional regulator  35.55 
 
 		 218 aa  145  5e-34  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.49018  normal  1 
 
 
-
 
NC_009972  Haur_0983  two component LuxR family transcriptional regulator  36.28 
 
 		 213 aa  143  2e-33  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  1  n/a   
 
 
-
 
NC_011769  DvMF_1021  two component transcriptional regulator, LuxR family  36.45 
 
 		 216 aa  136  2e-31  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.794365 
 
 
-
 
NC_013552  DhcVS_934  DNA-binding response regulator, LuxR family  37.25 
 
 		 232 aa  136  3.0000000000000003e-31  Dehalococcoides sp. VS  Bacteria  normal  0.717523  n/a   
 
 
-
 
NC_008751  Dvul_0670  two component LuxR family transcriptional regulator  36.45 
 
 		 216 aa  135  4e-31  Desulfovibrio vulgaris DP4  Bacteria  normal  0.267154  normal  1 
 
 
-
 
NC_009455  DehaBAV1_0945  two component LuxR family transcriptional regulator  37.07 
 
 		 232 aa  132  3e-30  Dehalococcoides sp. BAV1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009901  Spea_2299  two component LuxR family transcriptional regulator  34.13 
 
 		 221 aa  130  2.0000000000000002e-29  Shewanella pealeana ATCC 700345  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET1063  LuxR family DNA-binding response regulator  35.12 
 
 		 232 aa  129  3e-29  Dehalococcoides ethenogenes 195  Bacteria  normal  0.815436  n/a   
 
 
-
 
NC_009675  Anae109_1810  two component LuxR family transcriptional regulator  33.65 
 
 		 218 aa  127  1.0000000000000001e-28  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011830  Dhaf_1194  two component transcriptional regulator, LuxR family  33.97 
 
 		 217 aa  126  2.0000000000000002e-28  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.272513  n/a   
 
 
-
 
NC_011662  Tmz1t_1954  two component transcriptional regulator, LuxR family  35.5 
 
 		 220 aa  127  2.0000000000000002e-28  Thauera sp. MZ1T  Bacteria  normal  0.228638  n/a   
 
 
-
 
NC_007519  Dde_2674  two component LuxR family transcriptional regulator  30.95 
 
 		 215 aa  126  2.0000000000000002e-28  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.721789  n/a   
 
 
-
 
NC_009943  Dole_0029  two component LuxR family transcriptional regulator  34.47 
 
 		 214 aa  126  2.0000000000000002e-28  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.317943  n/a   
 
 
-
 
NC_002976  SERP1981  transcriptional regulatory protein DegU, putative  32.26 
 
 		 218 aa  126  3e-28  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_010511  M446_5717  two component LuxR family transcriptional regulator  32.35 
 
 		 220 aa  125  4.0000000000000003e-28  Methylobacterium sp. 4-46  Bacteria  normal  0.873964  hitchhiker  0.00405289 
 
 
-
 
NC_009487  SaurJH9_2415  two component LuxR family transcriptional regulator  33.33 
 
 		 217 aa  125  5e-28  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_2463  response regulator receiver  33.33 
 
 		 217 aa  125  5e-28  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  1  n/a   
 
 
-
 
NC_007974  Rmet_4715  Two component LuxR family transcriptional regulator  32.7 
 
 		 264 aa  125  5e-28  Cupriavidus metallidurans CH34  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010676  Bphyt_6235  two component transcriptional regulator, LuxR family  32.2 
 
 		 210 aa  125  6e-28  Burkholderia phytofirmans PsJN  Bacteria  normal  1  normal  0.612124 
 
 
-
 
NC_002939  GSU3229  LuxR family DNA-binding response regulator  31.16 
 
 		 229 aa  124  1e-27  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_010571  Oter_3186  two component LuxR family transcriptional regulator  33.01 
 
 		 215 aa  124  1e-27  Opitutus terrae PB90-1  Bacteria  normal  0.0678517  normal  1 
 
 
-
 
NC_003295  RSc2312  two-component response regulator transcription regulator protein  32.55 
 
 		 238 aa  123  2e-27  Ralstonia solanacearum GMI1000  Bacteria  normal  1  normal  0.500036 
 
 
-
 
NC_013204  Elen_1743  two component transcriptional regulator, LuxR family  31.43 
 
 		 214 aa  123  2e-27  Eggerthella lenta DSM 2243  Bacteria  normal  0.370009  normal  0.039988 
 
 
-
 
NC_007519  Dde_0977  two component LuxR family transcriptional regulator  31.07 
 
 		 223 aa  123  2e-27  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  decreased coverage  0.00800748  n/a   
 
 
-
 
NC_008255  CHU_1317  response regulator  31.78 
 
 		 220 aa  123  2e-27  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  0.500574  normal  0.0503905 
 
 
-
 
NC_010571  Oter_1700  two component LuxR family transcriptional regulator  34.78 
 
 		 213 aa  122  3e-27  Opitutus terrae PB90-1  Bacteria  normal  1  normal  0.226192 
 
 
-
 
NC_010571  Oter_0829  two component LuxR family transcriptional regulator  32.7 
 
 		 219 aa  122  4e-27  Opitutus terrae PB90-1  Bacteria  normal  1  normal  0.0121621 
 
 
-
 
NC_013170  Ccur_06630  response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein  33.02 
 
 		 215 aa  122  5e-27  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.252447  normal  0.303532 
 
 
-
 
NC_007760  Adeh_1997  two component LuxR family transcriptional regulator  33.18 
 
 		 218 aa  121  6e-27  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  1  n/a   
 
 
-
 
NC_010625  Bphy_6469  two component LuxR family transcriptional regulator  32.84 
 
 		 213 aa  121  8e-27  Burkholderia phymatum STM815  Bacteria  normal  1  normal  0.53826 
 
 
-
 
NC_010002  Daci_1809  two component LuxR family transcriptional regulator  33.01 
 
 		 210 aa  121  8e-27  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011145  AnaeK_1881  two component transcriptional regulator, LuxR family  33.18 
 
 		 218 aa  120  9.999999999999999e-27  Anaeromyxobacter sp. K  Bacteria  normal  0.0160211  n/a   
 
 
-
 
NC_011891  A2cp1_1966  two component transcriptional regulator, LuxR family  33.18 
 
 		 218 aa  120  9.999999999999999e-27  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_007974  Rmet_4516  two component LuxR family transcriptional regulator  33.01 
 
 		 214 aa  121  9.999999999999999e-27  Cupriavidus metallidurans CH34  Bacteria  normal  0.0463384  normal  0.0270495 
 
 
-
 
NC_009441  Fjoh_4628  two component LuxR family transcriptional regulator  29.77 
 
 		 219 aa  120  9.999999999999999e-27  Flavobacterium johnsoniae UW101  Bacteria  normal  1  n/a   
 
 
-
 
NC_010625  Bphy_6558  two component LuxR family transcriptional regulator  32.04 
 
 		 210 aa  120  9.999999999999999e-27  Burkholderia phymatum STM815  Bacteria  normal  1  normal  0.458284 
 
 
-
 
NC_007298  Daro_2343  two component LuxR family transcriptional regulator  32.35 
 
 		 211 aa  120  1.9999999999999998e-26  Dechloromonas aromatica RCB  Bacteria  normal  0.999882  normal  0.0841394 
 
 
-
 
NC_010338  Caul_2685  two component LuxR family transcriptional regulator  32.39 
 
 		 222 aa  120  1.9999999999999998e-26  Caulobacter sp. K31  Bacteria  normal  0.120511  normal  1 
 
 
-
 
NC_010627  Bphy_7761  two component LuxR family transcriptional regulator  32.34 
 
 		 213 aa  119  3e-26  Burkholderia phymatum STM815  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011830  Dhaf_1230  two component transcriptional regulator, LuxR family  33.98 
 
 		 215 aa  119  3e-26  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_013757  Gobs_2941  two component transcriptional regulator, LuxR family  34.12 
 
 		 219 aa  119  3e-26  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.911135  n/a   
 
 
-
 
NC_008255  CHU_0105  two component LuxR family transcriptional regulator  30.14 
 
 		 215 aa  119  3e-26  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  0.0303042  normal  0.309888 
 
 
-
 
NC_009439  Pmen_0083  two component LuxR family transcriptional regulator  35.32 
 
 		 210 aa  119  3e-26  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008576  Mmc1_2093  two component LuxR family transcriptional regulator  33.01 
 
 		 206 aa  119  3e-26  Magnetococcus sp. MC-1  Bacteria  hitchhiker  0.000328625  normal  0.180863 
 
 
-
 
NC_009052  Sbal_0792  two component LuxR family transcriptional regulator  35.96 
 
 		 209 aa  119  3.9999999999999996e-26  Shewanella baltica OS155  Bacteria  hitchhiker  0.000000151034  n/a   
 
 
-
 
NC_009665  Shew185_3713  two component LuxR family transcriptional regulator  35.96 
 
 		 209 aa  119  3.9999999999999996e-26  Shewanella baltica OS185  Bacteria  hitchhiker  0.000000000161759  n/a   
 
 
-
 
NC_011663  Sbal223_3654  two component transcriptional regulator, LuxR family  35.96 
 
 		 209 aa  119  3.9999999999999996e-26  Shewanella baltica OS223  Bacteria  unclonable  0.000000000464283  hitchhiker  0.00000781977 
 
 
-
 
NC_009997  Sbal195_3836  two component LuxR family transcriptional regulator  35.96 
 
 		 209 aa  119  3.9999999999999996e-26  Shewanella baltica OS195  Bacteria  hitchhiker  0.00000136397  normal  0.0231387 
 
 
-
 
NC_008782  Ajs_3509  two component LuxR family transcriptional regulator  32.06 
 
 		 239 aa  119  3.9999999999999996e-26  Acidovorax sp. JS42  Bacteria  normal  0.325902  normal  1 
 
 
-
 
NC_011992  Dtpsy_2832  two component transcriptional regulator, LuxR family  32.06 
 
 		 210 aa  119  4.9999999999999996e-26  Acidovorax ebreus TPSY  Bacteria  normal  0.988429  n/a   
 
 
-
 
NC_010725  Mpop_3747  two component transcriptional regulator, LuxR family  28.99 
 
 		 221 aa  119  4.9999999999999996e-26  Methylobacterium populi BJ001  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009512  Pput_3615  two component LuxR family transcriptional regulator  32.39 
 
 		 219 aa  118  6e-26  Pseudomonas putida F1  Bacteria  normal  0.378192  normal  0.274637 
 
 
-
 
NC_010718  Nther_0648  two component transcriptional regulator, LuxR family  34.93 
 
 		 215 aa  118  7.999999999999999e-26  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007973  Rmet_0090  two component LuxR family transcriptional regulator  30.62 
 
 		 210 aa  117  9.999999999999999e-26  Cupriavidus metallidurans CH34  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008321  Shewmr4_0657  two component LuxR family transcriptional regulator  35.15 
 
 		 209 aa  117  9.999999999999999e-26  Shewanella sp. MR-4  Bacteria  hitchhiker  0.000000493749  normal  0.229808 
 
 
-
 
NC_008322  Shewmr7_3365  two component LuxR family transcriptional regulator  35.15 
 
 		 209 aa  117  9.999999999999999e-26  Shewanella sp. MR-7  Bacteria  hitchhiker  0.0000651556  normal  0.0242167 
 
 
-
 
NC_008340  Mlg_2722  two component LuxR family transcriptional regulator  31.07 
 
 		 214 aa  117  9.999999999999999e-26  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  1  normal  0.378798 
 
 
-
 
NC_008577  Shewana3_0656  two component LuxR family transcriptional regulator  35.15 
 
 		 209 aa  117  9.999999999999999e-26  Shewanella sp. ANA-3  Bacteria  hitchhiker  0.000000830399  normal  0.140804 
 
 
-
 
NC_013456  VEA_003136  transcriptional regulator LuxR family protein  31.43 
 
 		 212 aa  117  9.999999999999999e-26  Vibrio sp. Ex25  Bacteria  normal  0.12843  n/a   
 
 
-
 
NC_010322  PputGB1_1667  two component LuxR family transcriptional regulator  31.46 
 
 		 219 aa  117  9.999999999999999e-26  Pseudomonas putida GB-1  Bacteria  normal  1  normal  0.869411 
 
 
-
 
NC_009656  PSPA7_0745  putative two-component response regulator  32.37 
 
 		 210 aa  116  1.9999999999999998e-25  Pseudomonas aeruginosa PA7  Bacteria  normal  0.536324  n/a   
 
 
-
 
NC_002947  PP_2126  LuxR family DNA-binding response regulator  31.92 
 
 		 219 aa  116  1.9999999999999998e-25  Pseudomonas putida KT2440  Bacteria  normal  0.118459  normal  0.107719 
 
 
-
 
NC_011883  Ddes_0810  two component transcriptional regulator, LuxR family  31.53 
 
 		 223 aa  116  1.9999999999999998e-25  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  0.935684  n/a   
 
 
-
 
NC_008752  Aave_3862  two component LuxR family transcriptional regulator  31.58 
 
 		 210 aa  117  1.9999999999999998e-25  Acidovorax citrulli AAC00-1  Bacteria  normal  0.734244  normal  1 
 
 
-
 
NC_011894  Mnod_0851  two component transcriptional regulator, LuxR family  30.58 
 
 		 232 aa  115  3e-25  Methylobacterium nodulans ORS 2060  Bacteria  normal  1  n/a   
 
 
-
 
NC_010505  Mrad2831_3042  two component LuxR family transcriptional regulator  30.73 
 
 		 222 aa  116  3e-25  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  1  normal  0.280021 
 
 
-
 
NC_013739  Cwoe_1233  two component transcriptional regulator, LuxR family  32.23 
 
 		 220 aa  115  3e-25  Conexibacter woesei DSM 14684  Bacteria  normal  0.681342  normal  0.792953 
 
 
-
 
NC_009441  Fjoh_4664  two component LuxR family transcriptional regulator  31.19 
 
 		 219 aa  115  3e-25  Flavobacterium johnsoniae UW101  Bacteria  normal  1  n/a   
 
 
-
 
NC_010682  Rpic_3729  two component transcriptional regulator, LuxR family  31 
 
 		 214 aa  115  3.9999999999999997e-25  Ralstonia pickettii 12J  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013595  Sros_6032  response regulator receiver protein  32.7 
 
 		 218 aa  115  3.9999999999999997e-25  Streptosporangium roseum DSM 43021  Bacteria  normal  0.53611  normal  1 
 
 
-
 
NC_007908  Rfer_0894  two component LuxR family transcriptional regulator  29.95 
 
 		 217 aa  115  3.9999999999999997e-25  Rhodoferax ferrireducens T118  Bacteria  normal  1  n/a   
 
 
-
 
NC_008781  Pnap_2640  two component LuxR family transcriptional regulator  33.17 
 
 		 205 aa  115  3.9999999999999997e-25  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.437778  normal  1 
 
 
-
 
NC_009012  Cthe_1267  two component LuxR family transcriptional regulator  32.68 
 
 		 216 aa  115  5e-25  Clostridium thermocellum ATCC 27405  Bacteria  normal  1  n/a   
 
 
-
 
NC_010468  EcolC_1725  response regulator  31.53 
 
 		 218 aa  115  5e-25  Escherichia coli ATCC 8739  Bacteria  hitchhiker  0.000351159  normal  1 
 
 
-
 
NC_007951  Bxe_A4347  two component LuxR family transcriptional regulator  28.85 
 
 		 218 aa  115  5e-25  Burkholderia xenovorans LB400  Bacteria  normal  1  normal  0.705126 
 
 
-
 
NC_013061  Phep_2962  response regulator receiver  33.17 
 
 		 206 aa  115  5e-25  Pedobacter heparinus DSM 2366  Bacteria  normal  0.117851  normal  1 
 
 
-
 
NC_009438  Sputcn32_0683  two component LuxR family transcriptional regulator  34.5 
 
 		 209 aa  115  5e-25  Shewanella putrefaciens CN-32  Bacteria  unclonable  0.000000000388278  n/a   
 
 
-
 
NC_008463  PA14_07840  putative two-component response regulator  31.88 
 
 		 210 aa  115  5e-25  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  1  normal  0.0171986 
 
 
-
 
NC_012856  Rpic12D_3406  two component transcriptional regulator, LuxR family  31 
 
 		 214 aa  115  6e-25  Ralstonia pickettii 12D  Bacteria  normal  0.588591  normal  1 
 
 
-
 
NC_007952  Bxe_B2471  two component LuxR family transcriptional regulator  29.47 
 
 		 220 aa  115  6e-25  Burkholderia xenovorans LB400  Bacteria  normal  1  normal  0.55611 
 
 
-
 
NC_009654  Mmwyl1_0679  two component LuxR family transcriptional regulator  32.85 
 
 		 213 aa  115  6e-25  Marinomonas sp. MWYL1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013946  Mrub_1071  two component LuxR family transcriptional regulator  31.5 
 
 		 209 aa  115  6e-25  Meiothermus ruber DSM 1279  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008700  Sama_0646  response regulator receiver protein  36.14 
 
 		 209 aa  115  6e-25  Shewanella amazonensis SB2B  Bacteria  normal  0.0492071  normal  1 
 
 
-
 
NC_010571  Oter_3372  two component LuxR family transcriptional regulator  32.38 
 
 		 212 aa  114  6.9999999999999995e-25  Opitutus terrae PB90-1  Bacteria  normal  1  normal  0.383896 
 
 
-
 
NC_007520  Tcr_1382  two component LuxR family transcriptional regulator  32.58 
 
 		 232 aa  115  6.9999999999999995e-25  Thiomicrospira crunogena XCL-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_008228  Patl_2450  two component LuxR family transcriptional regulator  31.88 
 
 		 214 aa  114  7.999999999999999e-25  Pseudoalteromonas atlantica T6c  Bacteria  hitchhiker  0.00539256  n/a   
 
 
-
 
NC_004116  SAG0322  DNA-binding response regulator  33.17 
 
 		 213 aa  114  1.0000000000000001e-24  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_011884  Cyan7425_4561  two component transcriptional regulator, LuxR family  29.86 
 
 		 217 aa  114  1.0000000000000001e-24  Cyanothece sp. PCC 7425  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009901  Spea_0829  two component LuxR family transcriptional regulator  32.67 
 
 		 209 aa  114  1.0000000000000001e-24  Shewanella pealeana ATCC 700345  Bacteria  hitchhiker  0.00236991  n/a   
 
 
-
 
NC_008786  Veis_0032  two component LuxR family transcriptional regulator  31.58 
 
 		 210 aa  114  1.0000000000000001e-24  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.245451  normal  1 
 
 
-
 
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