89 homologs were found in PanDaTox collection
for query gene Nther_1771 on replicon NC_010718
Organism: Natranaerobius thermophilus JW/NM-WN-LF



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_010718  Nther_1771  2-hydroxyglutaryl-CoA dehydratase D-component  100 
 
 		 419 aa  867    Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.433973 
 
 
-
 
NC_007644  Moth_1006  2-hydroxyglutaryl-CoA dehydratase, D-component  39.52 
 
 		 421 aa  343  2.9999999999999997e-93  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.0695891  hitchhiker  0.000177823 
 
 
-
 
NC_013385  Adeg_1707  2-hydroxyglutaryl-CoA dehydratase D-component  39.61 
 
 		 415 aa  298  2e-79  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011899  Hore_16080  2-hydroxyglutaryl-CoA dehydratase D-component  38.3 
 
 		 426 aa  266  4e-70  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_010320  Teth514_1899  2-hydroxyglutaryl-CoA dehydratase, D-component  28.2 
 
 		 416 aa  182  7e-45  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_011661  Dtur_1746  2-hydroxyglutaryl-CoA dehydratase D-component  30.81 
 
 		 408 aa  174  2.9999999999999996e-42  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_012034  Athe_0199  2-hydroxyglutaryl-CoA dehydratase D-component  25.46 
 
 		 416 aa  170  4e-41  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.00000602439  n/a   
 
 
-
 
NC_007925  RPC_2056  2-hydroxyglutaryl-CoA dehydratase, D-component  28.65 
 
 		 405 aa  138  1e-31  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  0.727818 
 
 
-
 
NC_009943  Dole_1685  2-hydroxyglutaryl-CoA dehydratase D-component  23.14 
 
 		 424 aa  107  4e-22  Desulfococcus oleovorans Hxd3  Bacteria  hitchhiker  0.00000455282  n/a   
 
 
-
 
NC_011830  Dhaf_3453  2-hydroxyglutaryl-CoA dehydratase D-component  24.66 
 
 		 409 aa  105  2e-21  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_011146  Gbem_2040  2-hydroxyglutaryl-CoA dehydratase D-component  21.39 
 
 		 401 aa  92  2e-17  Geobacter bemidjiensis Bem  Bacteria  normal  0.921137  n/a   
 
 
-
 
NC_011662  Tmz1t_2950  benzoyl-CoA reductase, subunit B  22.71 
 
 		 432 aa  89.7  8e-17  Thauera sp. MZ1T  Bacteria  normal  1  n/a   
 
 
-
 
NC_012918  GM21_2867  Benzoyl-CoA reductase  22.7 
 
 		 415 aa  89.4  1e-16  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_011883  Ddes_0545  2-hydroxyglutaryl-CoA dehydratase D-component  22.28 
 
 		 379 aa  85.1  0.000000000000002  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_011146  Gbem_1413  2-hydroxyglutaryl-CoA dehydratase D-component  23.02 
 
 		 415 aa  84.3  0.000000000000004  Geobacter bemidjiensis Bem  Bacteria  normal  0.657921  n/a   
 
 
-
 
NC_014150  Bmur_0617  2-hydroxyglutaryl-CoA dehydratase D-component  23.29 
 
 		 384 aa  83.6  0.000000000000006  Brachyspira murdochii DSM 12563  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0412  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  24.79 
 
 		 424 aa  82.8  0.00000000000001  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_008554  Sfum_3161  2-hydroxyglutaryl-CoA dehydratase, D-component  22.79 
 
 		 382 aa  82.4  0.00000000000001  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010718  Nther_0828  2-hydroxyglutaryl-CoA dehydratase D-component  23.4 
 
 		 393 aa  81.3  0.00000000000003  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  hitchhiker  0.0000331904 
 
 
-
 
NC_010468  EcolC_3728  2-hydroxyglutaryl-CoA dehydratase D-component  23.12 
 
 		 383 aa  80.9  0.00000000000004  Escherichia coli ATCC 8739  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007958  RPD_1537  benzoyl-CoA reductase, subunit B  22.71 
 
 		 436 aa  80.1  0.00000000000006  Rhodopseudomonas palustris BisB5  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011004  Rpal_0725  benzoyl-CoA reductase, subunit B  22.71 
 
 		 436 aa  79.7  0.00000000000008  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.0743165  n/a   
 
 
-
 
NC_010498  EcSMS35_4882  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  22.85 
 
 		 383 aa  79.7  0.00000000000009  Escherichia coli SMS-3-5  Bacteria  normal  0.30993  normal  0.992487 
 
 
-
 
NC_011769  DvMF_0986  2-hydroxyglutaryl-CoA dehydratase D-component  22.25 
 
 		 379 aa  79.3  0.0000000000001  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.345407 
 
 
-
 
NC_011353  ECH74115_5849  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  22.85 
 
 		 383 aa  78.6  0.0000000000002  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  1  normal  0.981774 
 
 
-
 
NC_011832  Mpal_1311  2-hydroxyglutaryl-CoA dehydratase D-component  22.64 
 
 		 388 aa  78.2  0.0000000000003  Methanosphaerula palustris E1-9c  Archaea  normal  0.522959  normal  1 
 
 
-
 
NC_002939  GSU2519  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  20.31 
 
 		 387 aa  77.8  0.0000000000004  Geobacter sulfurreducens PCA  Bacteria  normal  0.321633  n/a   
 
 
-
 
NC_012892  B21_04167  hypothetical protein  22.58 
 
 		 383 aa  77.4  0.0000000000005  Escherichia coli BL21  Bacteria  normal  0.0394396  n/a   
 
 
-
 
NC_013165  Shel_26180  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  22.41 
 
 		 384 aa  77.4  0.0000000000005  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013517  Sterm_1694  2-hydroxyglutaryl-CoA dehydratase D-component  22.02 
 
 		 382 aa  77.4  0.0000000000005  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
CP001637  EcDH1_3660  2-hydroxyglutaryl-CoA dehydratase D-component  22.58 
 
 		 383 aa  77.4  0.0000000000005  Escherichia coli DH1  Bacteria  normal  0.814301  n/a   
 
 
-
 
CP001509  ECD_04204  predicted 2-hydroxyglutaryl-CoA dehydratase  22.58 
 
 		 383 aa  77.4  0.0000000000005  Escherichia coli BL21(DE3)  Bacteria  normal  0.0605066  n/a   
 
 
-
 
NC_009800  EcHS_A4563  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  22.31 
 
 		 383 aa  77  0.0000000000006  Escherichia coli HS  Bacteria  normal  1  n/a   
 
 
-
 
NC_007925  RPC_1028  benzoyl-CoA reductase, subunit B  22.22 
 
 		 436 aa  76.3  0.0000000000009  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.659729  normal  1 
 
 
-
 
NC_009135  MmarC5_0834  2-hydroxyglutaryl-CoA dehydratase, D-component  21.8 
 
 		 373 aa  75.9  0.000000000001  Methanococcus maripaludis C5  Archaea  normal  1  n/a   
 
 
-
 
NC_009637  MmarC7_0081  2-hydroxyglutaryl-CoA dehydratase D-component  22.47 
 
 		 373 aa  76.3  0.000000000001  Methanococcus maripaludis C7  Archaea  hitchhiker  0.00790728  hitchhiker  0.00027984 
 
 
-
 
NC_009943  Dole_2775  2-hydroxyglutaryl-CoA dehydratase D-component  21.77 
 
 		 469 aa  75.1  0.000000000002  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_009634  Mevan_1356  2-hydroxyglutaryl-CoA dehydratase D-component  22.28 
 
 		 373 aa  75.5  0.000000000002  Methanococcus vannielii SB  Archaea  normal  0.0888918  n/a   
 
 
-
 
NC_009801  EcE24377A_4937  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  22.31 
 
 		 383 aa  75.5  0.000000000002  Escherichia coli E24377A  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_1465  2-hydroxyglutaryl-CoA dehydratase D-component  24.19 
 
 		 369 aa  73.2  0.000000000008  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011830  Dhaf_1100  2-hydroxyglutaryl-CoA dehydratase D-component  21.39 
 
 		 436 aa  73.2  0.000000000008  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009975  MmarC6_1821  2-hydroxyglutaryl-CoA dehydratase D-component  22.19 
 
 		 373 aa  73.2  0.000000000009  Methanococcus maripaludis C6  Archaea  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_2825  2-hydroxyglutaryl-CoA dehydratase D-component  24.59 
 
 		 368 aa  72.4  0.00000000001  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008346  Swol_0410  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  20.98 
 
 		 378 aa  72.8  0.00000000001  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.732282  n/a   
 
 
-
 
NC_008751  Dvul_0706  2-hydroxyglutaryl-CoA dehydratase, D-component  21.12 
 
 		 380 aa  72.4  0.00000000001  Desulfovibrio vulgaris DP4  Bacteria  normal  0.255737  normal  0.505258 
 
 
-
 
NC_013165  Shel_25470  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  24.18 
 
 		 425 aa  71.6  0.00000000002  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009943  Dole_0892  2-hydroxyglutaryl-CoA dehydratase D-component  18.86 
 
 		 481 aa  72  0.00000000002  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_0866  2-hydroxyglutaryl-CoA dehydratase, D-component  21.53 
 
 		 383 aa  72.4  0.00000000002  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.327302  normal  1 
 
 
-
 
NC_010718  Nther_1772  2-hydroxyglutaryl-CoA dehydratase D-component  22.72 
 
 		 358 aa  70.5  0.00000000005  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.39587 
 
 
-
 
NC_009943  Dole_0931  2-hydroxyglutaryl-CoA dehydratase D-component  21.72 
 
 		 419 aa  69.7  0.00000000009  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_0119  2-hydroxyglutaryl-CoA dehydratase D-component  23.58 
 
 		 424 aa  68.2  0.0000000003  Desulfotomaculum acetoxidans DSM 771  Bacteria  hitchhiker  0.000350126  normal  0.0170821 
 
 
-
 
NC_008346  Swol_0427  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  22.37 
 
 		 382 aa  67.8  0.0000000003  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_009715  CCV52592_0873  2-hydroxyglutaryl-CoA dehydratase, D-component  20.39 
 
 		 385 aa  67.4  0.0000000004  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1418  2-hydroxyglutaryl-CoA dehydratase, D-component  23.77 
 
 		 436 aa  67.8  0.0000000004  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00133287  normal  0.906732 
 
 
-
 
NC_009634  Mevan_1623  2-hydroxyglutaryl-CoA dehydratase D-component  22.56 
 
 		 373 aa  67  0.0000000005  Methanococcus vannielii SB  Archaea  decreased coverage  0.000208392  n/a   
 
 
-
 
NC_009802  CCC13826_1134  UDP-MurNac-pentapeptide presynthetase  24.38 
 
 		 385 aa  67  0.0000000006  Campylobacter concisus 13826  Bacteria  normal  0.207036  n/a   
 
 
-
 
NC_002967  TDE0392  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  21.87 
 
 		 392 aa  67  0.0000000006  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_3912  2-hydroxyglutaryl-CoA dehydratase D-component  20.96 
 
 		 384 aa  66.2  0.000000001  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_002967  TDE0389  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  23.6 
 
 		 412 aa  65.5  0.000000002  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_013204  Elen_1690  2-hydroxyglutaryl-CoA dehydratase D-component  24.73 
 
 		 424 aa  65.1  0.000000002  Eggerthella lenta DSM 2243  Bacteria  normal  0.531982  normal  0.740952 
 
 
-
 
NC_009253  Dred_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  21.72 
 
 		 385 aa  63.9  0.000000005  Desulfotomaculum reducens MI-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013170  Ccur_11360  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  24.17 
 
 		 426 aa  62.4  0.00000001  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.390545  normal  0.8731 
 
 
-
 
NC_013512  Sdel_2024  2-hydroxyglutaryl-CoA dehydratase D-component  21.28 
 
 		 439 aa  62  0.00000002  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_1346  2-hydroxyglutaryl-CoA dehydratase D-component  21.01 
 
 		 372 aa  61.2  0.00000004  Methanococcus aeolicus Nankai-3  Archaea  normal  0.120946  n/a   
 
 
-
 
NC_009975  MmarC6_0607  2-hydroxyglutaryl-CoA dehydratase D-component  21.02 
 
 		 373 aa  60.5  0.00000006  Methanococcus maripaludis C6  Archaea  normal  0.422107  n/a   
 
 
-
 
NC_009135  MmarC5_1329  2-hydroxyglutaryl-CoA dehydratase, D-component  21.02 
 
 		 373 aa  59.7  0.0000001  Methanococcus maripaludis C5  Archaea  normal  0.360165  n/a   
 
 
-
 
NC_009712  Mboo_0863  2-hydroxyglutaryl-CoA dehydratase, D-component  23.12 
 
 		 426 aa  59.3  0.0000001  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.0455624  normal  1 
 
 
-
 
NC_013385  Adeg_0387  2-hydroxyglutaryl-CoA dehydratase D-component  23.92 
 
 		 426 aa  58.9  0.0000002  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_3878  2-hydroxyglutaryl-CoA dehydratase, D-component  24.54 
 
 		 472 aa  57.8  0.0000003  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1007  2-hydroxyglutaryl-CoA dehydratase, D-component  27.51 
 
 		 349 aa  57.4  0.0000005  Moorella thermoacetica ATCC 39073  Bacteria  decreased coverage  0.0000000530359  hitchhiker  0.000167288 
 
 
-
 
NC_007575  Suden_0273  2-hydroxyglutaryl-CoA dehydratase, D-component  21.98 
 
 		 422 aa  56.6  0.0000008  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  1  n/a   
 
 
-
 
NC_009637  MmarC7_1346  2-hydroxyglutaryl-CoA dehydratase D-component  20.51 
 
 		 373 aa  55.8  0.000001  Methanococcus maripaludis C7  Archaea  normal  0.922776  normal  0.0249494 
 
 
-
 
NC_013385  Adeg_1708  2-hydroxyglutaryl-CoA dehydratase D-component  22.26 
 
 		 322 aa  56.2  0.000001  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_1101  2-hydroxyglutaryl-CoA dehydratase D-component  20.95 
 
 		 379 aa  55.8  0.000001  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_2770  2-hydroxyglutaryl-CoA dehydratase D-component  20.45 
 
 		 466 aa  55.1  0.000002  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_013522  Taci_0254  2-hydroxyglutaryl-CoA dehydratase D-component  22.1 
 
 		 423 aa  53.9  0.000006  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  1  n/a   
 
 
-
 
NC_008554  Sfum_3256  2-hydroxyglutaryl-CoA dehydratase, D-component  22.91 
 
 		 423 aa  52.8  0.00001  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007925  RPC_2055  2-hydroxyglutaryl-CoA dehydratase, D-component  21.21 
 
 		 376 aa  52.8  0.00001  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.574959  normal  0.736744 
 
 
-
 
NC_010814  Glov_2400  2-hydroxyglutaryl-CoA dehydratase D-component  20.63 
 
 		 425 aa  50.1  0.00007  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_1137  2-hydroxyglutaryl-CoA dehydratase D-component  25.77 
 
 		 494 aa  48.9  0.0002  Methanosphaerula palustris E1-9c  Archaea  normal  0.417243  normal  1 
 
 
-
 
NC_009943  Dole_2769  2-hydroxyglutaryl-CoA dehydratase D-component  20.35 
 
 		 379 aa  47  0.0006  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_3454  2-hydroxyglutaryl-CoA dehydratase D-component  24.32 
 
 		 386 aa  47  0.0006  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_0891  2-hydroxyglutaryl-CoA dehydratase D-component  21.23 
 
 		 373 aa  45.8  0.001  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_011899  Hore_16090  2-hydroxyglutaryl-CoA dehydratase D-component  32.29 
 
 		 355 aa  45.4  0.002  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_013552  DhcVS_532  hypothetical protein  22.78 
 
 		 336 aa  45.4  0.002  Dehalococcoides sp. VS  Bacteria  hitchhiker  0.00368182  n/a   
 
 
-
 
NC_009483  Gura_0485  2-hydroxyglutaryl-CoA dehydratase, D-component  21.92 
 
 		 333 aa  45.1  0.002  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET0591  hypothetical protein  24.67 
 
 		 339 aa  44.7  0.003  Dehalococcoides ethenogenes 195  Bacteria  normal  0.114388  n/a   
 
 
-
 
NC_011832  Mpal_1135  2-hydroxyglutaryl-CoA dehydratase D-component  27.55 
 
 		 494 aa  43.5  0.007  Methanosphaerula palustris E1-9c  Archaea  normal  1  normal  0.207631 
 
 
-
 
NC_013216  Dtox_3625  2-hydroxyglutaryl-CoA dehydratase D-component  20.05 
 
 		 325 aa  43.5  0.008  Desulfotomaculum acetoxidans DSM 771  Bacteria  unclonable  0.00000000225912  normal  0.25533 
 
 
-
 
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