79 homologs were found in PanDaTox collection
for query gene Hore_16090 on replicon NC_011899
Organism: Halothermothrix orenii H 168



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_011899  Hore_16090  2-hydroxyglutaryl-CoA dehydratase D-component  100 
 
 		 355 aa  729    Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1772  2-hydroxyglutaryl-CoA dehydratase D-component  27.76 
 
 		 358 aa  118  1.9999999999999998e-25  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.39587 
 
 
-
 
NC_007644  Moth_1007  2-hydroxyglutaryl-CoA dehydratase, D-component  27.71 
 
 		 349 aa  110  5e-23  Moorella thermoacetica ATCC 39073  Bacteria  decreased coverage  0.0000000530359  hitchhiker  0.000167288 
 
 
-
 
NC_013385  Adeg_1708  2-hydroxyglutaryl-CoA dehydratase D-component  29.45 
 
 		 322 aa  107  2e-22  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011661  Dtur_1747  2-hydroxyglutaryl-CoA dehydratase D-component  25.69 
 
 		 339 aa  100  5e-20  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_011769  DvMF_0986  2-hydroxyglutaryl-CoA dehydratase D-component  24.71 
 
 		 379 aa  99.8  7e-20  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.345407 
 
 
-
 
NC_011883  Ddes_0545  2-hydroxyglutaryl-CoA dehydratase D-component  24.65 
 
 		 379 aa  97.4  3e-19  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_002939  GSU2519  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  24.59 
 
 		 387 aa  95.1  2e-18  Geobacter sulfurreducens PCA  Bacteria  normal  0.321633  n/a   
 
 
-
 
NC_009715  CCV52592_0873  2-hydroxyglutaryl-CoA dehydratase, D-component  23.78 
 
 		 385 aa  94.4  3e-18  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1418  2-hydroxyglutaryl-CoA dehydratase, D-component  26.11 
 
 		 436 aa  92.4  1e-17  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00133287  normal  0.906732 
 
 
-
 
NC_009943  Dole_2774  2-hydroxyglutaryl-CoA dehydratase D-component  24.25 
 
 		 376 aa  91.7  2e-17  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_0119  2-hydroxyglutaryl-CoA dehydratase D-component  23.5 
 
 		 424 aa  90.1  5e-17  Desulfotomaculum acetoxidans DSM 771  Bacteria  hitchhiker  0.000350126  normal  0.0170821 
 
 
-
 
NC_009802  CCC13826_1134  UDP-MurNac-pentapeptide presynthetase  23.85 
 
 		 385 aa  88.6  2e-16  Campylobacter concisus 13826  Bacteria  normal  0.207036  n/a   
 
 
-
 
NC_009943  Dole_1686  2-hydroxyglutaryl-CoA dehydratase D-component  24.41 
 
 		 370 aa  88.2  2e-16  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0274681  n/a   
 
 
-
 
NC_011830  Dhaf_3454  2-hydroxyglutaryl-CoA dehydratase D-component  24.64 
 
 		 386 aa  86.3  7e-16  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_0866  2-hydroxyglutaryl-CoA dehydratase, D-component  24.29 
 
 		 383 aa  86.3  8e-16  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.327302  normal  1 
 
 
-
 
NC_013512  Sdel_2024  2-hydroxyglutaryl-CoA dehydratase D-component  22.78 
 
 		 439 aa  84.7  0.000000000000002  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0412  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  25 
 
 		 424 aa  85.1  0.000000000000002  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_011146  Gbem_2040  2-hydroxyglutaryl-CoA dehydratase D-component  23.84 
 
 		 401 aa  85.1  0.000000000000002  Geobacter bemidjiensis Bem  Bacteria  normal  0.921137  n/a   
 
 
-
 
NC_007925  RPC_2055  2-hydroxyglutaryl-CoA dehydratase, D-component  24.27 
 
 		 376 aa  84.7  0.000000000000002  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.574959  normal  0.736744 
 
 
-
 
NC_009637  MmarC7_0081  2-hydroxyglutaryl-CoA dehydratase D-component  24.11 
 
 		 373 aa  84.3  0.000000000000003  Methanococcus maripaludis C7  Archaea  hitchhiker  0.00790728  hitchhiker  0.00027984 
 
 
-
 
NC_009975  MmarC6_1821  2-hydroxyglutaryl-CoA dehydratase D-component  24.11 
 
 		 373 aa  83.6  0.000000000000004  Methanococcus maripaludis C6  Archaea  normal  1  n/a   
 
 
-
 
NC_008751  Dvul_0706  2-hydroxyglutaryl-CoA dehydratase, D-component  22.51 
 
 		 380 aa  84  0.000000000000004  Desulfovibrio vulgaris DP4  Bacteria  normal  0.255737  normal  0.505258 
 
 
-
 
NC_007575  Suden_0273  2-hydroxyglutaryl-CoA dehydratase, D-component  25.27 
 
 		 422 aa  84  0.000000000000004  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_2769  2-hydroxyglutaryl-CoA dehydratase D-component  26.54 
 
 		 379 aa  83.2  0.000000000000006  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_014150  Bmur_0617  2-hydroxyglutaryl-CoA dehydratase D-component  23.01 
 
 		 384 aa  83.2  0.000000000000006  Brachyspira murdochii DSM 12563  Bacteria  normal  1  n/a   
 
 
-
 
NC_013385  Adeg_0387  2-hydroxyglutaryl-CoA dehydratase D-component  23.96 
 
 		 426 aa  82.8  0.000000000000008  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_009135  MmarC5_0834  2-hydroxyglutaryl-CoA dehydratase, D-component  23.91 
 
 		 373 aa  82.8  0.000000000000009  Methanococcus maripaludis C5  Archaea  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1446  2-hydroxyglutaryl-CoA dehydratase, D-component  25 
 
 		 381 aa  82.4  0.00000000000001  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.629308  normal  0.054659 
 
 
-
 
NC_013165  Shel_25330  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  22.44 
 
 		 390 aa  80.1  0.00000000000006  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  0.8257 
 
 
-
 
NC_013165  Shel_25470  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  24.58 
 
 		 425 aa  80.1  0.00000000000006  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008554  Sfum_3161  2-hydroxyglutaryl-CoA dehydratase, D-component  23.8 
 
 		 382 aa  79.3  0.00000000000009  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013517  Sterm_1694  2-hydroxyglutaryl-CoA dehydratase D-component  23.01 
 
 		 382 aa  79.3  0.0000000000001  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_013522  Taci_0254  2-hydroxyglutaryl-CoA dehydratase D-component  23.92 
 
 		 423 aa  78.2  0.0000000000002  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  1  n/a   
 
 
-
 
NC_008554  Sfum_3256  2-hydroxyglutaryl-CoA dehydratase, D-component  24.11 
 
 		 423 aa  78.6  0.0000000000002  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007519  Dde_0090  2-hydroxyglutaryl-CoA dehydratase, beta subunit-like  23.73 
 
 		 426 aa  77  0.0000000000005  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_013170  Ccur_11360  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  24.58 
 
 		 426 aa  77  0.0000000000005  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.390545  normal  0.8731 
 
 
-
 
NC_009634  Mevan_1356  2-hydroxyglutaryl-CoA dehydratase D-component  23.12 
 
 		 373 aa  75.9  0.000000000001  Methanococcus vannielii SB  Archaea  normal  0.0888918  n/a   
 
 
-
 
NC_011832  Mpal_1311  2-hydroxyglutaryl-CoA dehydratase D-component  22.05 
 
 		 388 aa  75.9  0.000000000001  Methanosphaerula palustris E1-9c  Archaea  normal  0.522959  normal  1 
 
 
-
 
NC_013204  Elen_1690  2-hydroxyglutaryl-CoA dehydratase D-component  24.03 
 
 		 424 aa  75.9  0.000000000001  Eggerthella lenta DSM 2243  Bacteria  normal  0.531982  normal  0.740952 
 
 
-
 
NC_013216  Dtox_2825  2-hydroxyglutaryl-CoA dehydratase D-component  24.42 
 
 		 368 aa  75.1  0.000000000002  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009634  Mevan_1623  2-hydroxyglutaryl-CoA dehydratase D-component  31.43 
 
 		 373 aa  75.1  0.000000000002  Methanococcus vannielii SB  Archaea  decreased coverage  0.000208392  n/a   
 
 
-
 
NC_011830  Dhaf_3912  2-hydroxyglutaryl-CoA dehydratase D-component  22.48 
 
 		 384 aa  73.6  0.000000000005  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_010320  Teth514_1898  putative CoA-substrate-specific enzyme activase  26.79 
 
 		 539 aa  73.6  0.000000000006  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_0891  2-hydroxyglutaryl-CoA dehydratase D-component  26.49 
 
 		 373 aa  72.8  0.000000000009  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_1465  2-hydroxyglutaryl-CoA dehydratase D-component  23.43 
 
 		 369 aa  72  0.00000000001  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_002967  TDE0392  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  24.59 
 
 		 392 aa  72.4  0.00000000001  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_002967  TDE0389  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  23.61 
 
 		 412 aa  70.9  0.00000000003  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_1346  2-hydroxyglutaryl-CoA dehydratase D-component  21.9 
 
 		 372 aa  68.6  0.0000000001  Methanococcus aeolicus Nankai-3  Archaea  normal  0.120946  n/a   
 
 
-
 
NC_009800  EcHS_A4563  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  23.23 
 
 		 383 aa  68.9  0.0000000001  Escherichia coli HS  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0427  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  31.94 
 
 		 382 aa  68.2  0.0000000002  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_1147  2-hydroxyglutaryl-CoA dehydratase D-component  24.4 
 
 		 393 aa  68.6  0.0000000002  Methanosphaerula palustris E1-9c  Archaea  normal  0.132933  normal  1 
 
 
-
 
NC_009637  MmarC7_1346  2-hydroxyglutaryl-CoA dehydratase D-component  29.08 
 
 		 373 aa  68.2  0.0000000002  Methanococcus maripaludis C7  Archaea  normal  0.922776  normal  0.0249494 
 
 
-
 
NC_009135  MmarC5_1329  2-hydroxyglutaryl-CoA dehydratase, D-component  27.66 
 
 		 373 aa  67.4  0.0000000003  Methanococcus maripaludis C5  Archaea  normal  0.360165  n/a   
 
 
-
 
NC_010498  EcSMS35_4882  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  22.66 
 
 		 383 aa  67  0.0000000005  Escherichia coli SMS-3-5  Bacteria  normal  0.30993  normal  0.992487 
 
 
-
 
NC_009975  MmarC6_0607  2-hydroxyglutaryl-CoA dehydratase D-component  22 
 
 		 373 aa  67  0.0000000005  Methanococcus maripaludis C6  Archaea  normal  0.422107  n/a   
 
 
-
 
CP001637  EcDH1_3660  2-hydroxyglutaryl-CoA dehydratase D-component  22.66 
 
 		 383 aa  66.6  0.0000000006  Escherichia coli DH1  Bacteria  normal  0.814301  n/a   
 
 
-
 
NC_013173  Dbac_1927  2-hydroxyglutaryl-CoA dehydratase D-component  23.31 
 
 		 425 aa  66.6  0.0000000006  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.756388  n/a   
 
 
-
 
NC_012892  B21_04167  hypothetical protein  22.66 
 
 		 383 aa  66.6  0.0000000006  Escherichia coli BL21  Bacteria  normal  0.0394396  n/a   
 
 
-
 
CP001509  ECD_04204  predicted 2-hydroxyglutaryl-CoA dehydratase  22.66 
 
 		 383 aa  66.6  0.0000000006  Escherichia coli BL21(DE3)  Bacteria  normal  0.0605066  n/a   
 
 
-
 
NC_009801  EcE24377A_4937  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  22.38 
 
 		 383 aa  65.9  0.000000001  Escherichia coli E24377A  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_1101  2-hydroxyglutaryl-CoA dehydratase D-component  26.55 
 
 		 379 aa  65.5  0.000000001  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_010468  EcolC_3728  2-hydroxyglutaryl-CoA dehydratase D-component  22.95 
 
 		 383 aa  64.7  0.000000003  Escherichia coli ATCC 8739  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011353  ECH74115_5849  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  22.66 
 
 		 383 aa  64.3  0.000000003  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  1  normal  0.981774 
 
 
-
 
NC_010718  Nther_0828  2-hydroxyglutaryl-CoA dehydratase D-component  21.51 
 
 		 393 aa  63.5  0.000000005  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  hitchhiker  0.0000331904 
 
 
-
 
NC_012034  Athe_0200  CoA-substrate-specific enzyme activase  23.21 
 
 		 539 aa  62.8  0.00000001  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.00000427749  n/a   
 
 
-
 
NC_008609  Ppro_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  21.63 
 
 		 413 aa  61.2  0.00000003  Pelobacter propionicus DSM 2379  Bacteria  normal  1  n/a   
 
 
-
 
NC_002939  GSU2944  (R)-2-hydroxyglutaryl-CoA dehydratase alpha-subunit, putative  23.18 
 
 		 431 aa  61.2  0.00000003  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_009253  Dred_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  22.79 
 
 		 385 aa  60.8  0.00000003  Desulfotomaculum reducens MI-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0410  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  19.6 
 
 		 378 aa  60.1  0.00000005  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.732282  n/a   
 
 
-
 
NC_010814  Glov_0091  2-hydroxyglutaryl-CoA dehydratase D-component  21.86 
 
 		 429 aa  60.1  0.00000006  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_0863  2-hydroxyglutaryl-CoA dehydratase, D-component  21.62 
 
 		 426 aa  54.3  0.000003  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.0455624  normal  1 
 
 
-
 
NC_010320  Teth514_1899  2-hydroxyglutaryl-CoA dehydratase, D-component  33 
 
 		 416 aa  50.4  0.00004  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_26180  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  25.52 
 
 		 384 aa  48.5  0.0002  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013385  Adeg_1707  2-hydroxyglutaryl-CoA dehydratase D-component  28.68 
 
 		 415 aa  47.8  0.0003  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1006  2-hydroxyglutaryl-CoA dehydratase, D-component  31 
 
 		 421 aa  45.8  0.001  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.0695891  hitchhiker  0.000177823 
 
 
-
 
NC_009483  Gura_3877  2-hydroxyglutaryl-CoA dehydratase, D-component  27.03 
 
 		 395 aa  46.2  0.001  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1771  2-hydroxyglutaryl-CoA dehydratase D-component  32.29 
 
 		 419 aa  45.4  0.002  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.433973 
 
 
-
 
NC_007925  RPC_1029  benzoyl-CoA reductase, subunit C  22.6 
 
 		 394 aa  42.7  0.01  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  1 
 
 
-
 
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