92 homologs were found in PanDaTox collection
for query gene RPC_2055 on replicon NC_007925
Organism: Rhodopseudomonas palustris BisB18



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_007925  RPC_2055  2-hydroxyglutaryl-CoA dehydratase, D-component  100 
 
 		 376 aa  772    Rhodopseudomonas palustris BisB18  Bacteria  normal  0.574959  normal  0.736744 
 
 
-
 
NC_011830  Dhaf_1101  2-hydroxyglutaryl-CoA dehydratase D-component  27.54 
 
 		 379 aa  143  5e-33  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1418  2-hydroxyglutaryl-CoA dehydratase, D-component  27.48 
 
 		 436 aa  134  3e-30  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00133287  normal  0.906732 
 
 
-
 
NC_010498  EcSMS35_4882  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  29.94 
 
 		 383 aa  131  2.0000000000000002e-29  Escherichia coli SMS-3-5  Bacteria  normal  0.30993  normal  0.992487 
 
 
-
 
NC_010468  EcolC_3728  2-hydroxyglutaryl-CoA dehydratase D-component  29.94 
 
 		 383 aa  130  3e-29  Escherichia coli ATCC 8739  Bacteria  normal  1  normal  1 
 
 
-
 
CP001637  EcDH1_3660  2-hydroxyglutaryl-CoA dehydratase D-component  29.66 
 
 		 383 aa  130  4.0000000000000003e-29  Escherichia coli DH1  Bacteria  normal  0.814301  n/a   
 
 
-
 
NC_009800  EcHS_A4563  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  29.66 
 
 		 383 aa  130  4.0000000000000003e-29  Escherichia coli HS  Bacteria  normal  1  n/a   
 
 
-
 
CP001509  ECD_04204  predicted 2-hydroxyglutaryl-CoA dehydratase  29.66 
 
 		 383 aa  130  4.0000000000000003e-29  Escherichia coli BL21(DE3)  Bacteria  normal  0.0605066  n/a   
 
 
-
 
NC_012892  B21_04167  hypothetical protein  29.66 
 
 		 383 aa  130  4.0000000000000003e-29  Escherichia coli BL21  Bacteria  normal  0.0394396  n/a   
 
 
-
 
NC_009943  Dole_2769  2-hydroxyglutaryl-CoA dehydratase D-component  27.79 
 
 		 379 aa  130  5.0000000000000004e-29  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_013517  Sterm_1694  2-hydroxyglutaryl-CoA dehydratase D-component  27.35 
 
 		 382 aa  130  5.0000000000000004e-29  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_011353  ECH74115_5849  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  29.66 
 
 		 383 aa  129  1.0000000000000001e-28  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  1  normal  0.981774 
 
 
-
 
NC_009943  Dole_2774  2-hydroxyglutaryl-CoA dehydratase D-component  27.25 
 
 		 376 aa  128  2.0000000000000002e-28  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_009801  EcE24377A_4937  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  29.1 
 
 		 383 aa  126  6e-28  Escherichia coli E24377A  Bacteria  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_1311  2-hydroxyglutaryl-CoA dehydratase D-component  27.37 
 
 		 388 aa  125  1e-27  Methanosphaerula palustris E1-9c  Archaea  normal  0.522959  normal  1 
 
 
-
 
NC_013216  Dtox_0119  2-hydroxyglutaryl-CoA dehydratase D-component  26.7 
 
 		 424 aa  124  2e-27  Desulfotomaculum acetoxidans DSM 771  Bacteria  hitchhiker  0.000350126  normal  0.0170821 
 
 
-
 
NC_013522  Taci_0254  2-hydroxyglutaryl-CoA dehydratase D-component  26.06 
 
 		 423 aa  124  3e-27  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_0828  2-hydroxyglutaryl-CoA dehydratase D-component  27.09 
 
 		 393 aa  124  3e-27  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  hitchhiker  0.0000331904 
 
 
-
 
NC_009943  Dole_0891  2-hydroxyglutaryl-CoA dehydratase D-component  27.83 
 
 		 373 aa  124  4e-27  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_011004  Rpal_0724  benzoyl-CoA reductase, subunit C  27.27 
 
 		 394 aa  122  9.999999999999999e-27  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.377082  n/a   
 
 
-
 
NC_007925  RPC_1029  benzoyl-CoA reductase, subunit C  26.96 
 
 		 394 aa  121  1.9999999999999998e-26  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007519  Dde_0090  2-hydroxyglutaryl-CoA dehydratase, beta subunit-like  26.14 
 
 		 426 aa  121  1.9999999999999998e-26  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_007958  RPD_1538  benzoyl-CoA reductase, subunit C  27.83 
 
 		 394 aa  121  1.9999999999999998e-26  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.130058  normal  1 
 
 
-
 
NC_011662  Tmz1t_2951  benzoyl-CoA reductase, subunit C  26.91 
 
 		 386 aa  118  9.999999999999999e-26  Thauera sp. MZ1T  Bacteria  normal  0.689086  n/a   
 
 
-
 
NC_013385  Adeg_0387  2-hydroxyglutaryl-CoA dehydratase D-component  24.93 
 
 		 426 aa  117  3.9999999999999997e-25  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_013170  Ccur_11360  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  24.87 
 
 		 426 aa  116  6.9999999999999995e-25  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.390545  normal  0.8731 
 
 
-
 
NC_002967  TDE0389  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  23.26 
 
 		 412 aa  116  7.999999999999999e-25  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0412  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  24.44 
 
 		 424 aa  115  1.0000000000000001e-24  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_3912  2-hydroxyglutaryl-CoA dehydratase D-component  25.93 
 
 		 384 aa  114  2.0000000000000002e-24  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_008751  Dvul_0706  2-hydroxyglutaryl-CoA dehydratase, D-component  28.77 
 
 		 380 aa  114  3e-24  Desulfovibrio vulgaris DP4  Bacteria  normal  0.255737  normal  0.505258 
 
 
-
 
NC_013165  Shel_25470  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  24.1 
 
 		 425 aa  113  4.0000000000000004e-24  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007644  Moth_1007  2-hydroxyglutaryl-CoA dehydratase, D-component  25.95 
 
 		 349 aa  113  7.000000000000001e-24  Moorella thermoacetica ATCC 39073  Bacteria  decreased coverage  0.0000000530359  hitchhiker  0.000167288 
 
 
-
 
NC_007644  Moth_1446  2-hydroxyglutaryl-CoA dehydratase, D-component  26.4 
 
 		 381 aa  112  7.000000000000001e-24  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.629308  normal  0.054659 
 
 
-
 
NC_008346  Swol_0410  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  25.63 
 
 		 378 aa  112  8.000000000000001e-24  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.732282  n/a   
 
 
-
 
NC_009135  MmarC5_1329  2-hydroxyglutaryl-CoA dehydratase, D-component  24.54 
 
 		 373 aa  112  8.000000000000001e-24  Methanococcus maripaludis C5  Archaea  normal  0.360165  n/a   
 
 
-
 
NC_011146  Gbem_2040  2-hydroxyglutaryl-CoA dehydratase D-component  27.47 
 
 		 401 aa  112  1.0000000000000001e-23  Geobacter bemidjiensis Bem  Bacteria  normal  0.921137  n/a   
 
 
-
 
NC_009975  MmarC6_0607  2-hydroxyglutaryl-CoA dehydratase D-component  25.07 
 
 		 373 aa  112  1.0000000000000001e-23  Methanococcus maripaludis C6  Archaea  normal  0.422107  n/a   
 
 
-
 
NC_009135  MmarC5_0834  2-hydroxyglutaryl-CoA dehydratase, D-component  25 
 
 		 373 aa  111  2.0000000000000002e-23  Methanococcus maripaludis C5  Archaea  normal  1  n/a   
 
 
-
 
NC_011769  DvMF_0986  2-hydroxyglutaryl-CoA dehydratase D-component  27.42 
 
 		 379 aa  111  2.0000000000000002e-23  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.345407 
 
 
-
 
NC_009975  MmarC6_1821  2-hydroxyglutaryl-CoA dehydratase D-component  25 
 
 		 373 aa  110  3e-23  Methanococcus maripaludis C6  Archaea  normal  1  n/a   
 
 
-
 
NC_009943  Dole_1686  2-hydroxyglutaryl-CoA dehydratase D-component  26.11 
 
 		 370 aa  111  3e-23  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0274681  n/a   
 
 
-
 
NC_014150  Bmur_0617  2-hydroxyglutaryl-CoA dehydratase D-component  25.27 
 
 		 384 aa  110  4.0000000000000004e-23  Brachyspira murdochii DSM 12563  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_2825  2-hydroxyglutaryl-CoA dehydratase D-component  26.65 
 
 		 368 aa  110  4.0000000000000004e-23  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009637  MmarC7_0081  2-hydroxyglutaryl-CoA dehydratase D-component  24.26 
 
 		 373 aa  110  6e-23  Methanococcus maripaludis C7  Archaea  hitchhiker  0.00790728  hitchhiker  0.00027984 
 
 
-
 
NC_009637  MmarC7_1346  2-hydroxyglutaryl-CoA dehydratase D-component  25.57 
 
 		 373 aa  109  7.000000000000001e-23  Methanococcus maripaludis C7  Archaea  normal  0.922776  normal  0.0249494 
 
 
-
 
NC_002939  GSU2519  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  27.45 
 
 		 387 aa  108  2e-22  Geobacter sulfurreducens PCA  Bacteria  normal  0.321633  n/a   
 
 
-
 
NC_011883  Ddes_0545  2-hydroxyglutaryl-CoA dehydratase D-component  25.21 
 
 		 379 aa  108  2e-22  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_002967  TDE0392  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  25.48 
 
 		 392 aa  108  2e-22  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_1346  2-hydroxyglutaryl-CoA dehydratase D-component  25.73 
 
 		 372 aa  107  4e-22  Methanococcus aeolicus Nankai-3  Archaea  normal  0.120946  n/a   
 
 
-
 
NC_002939  GSU2944  (R)-2-hydroxyglutaryl-CoA dehydratase alpha-subunit, putative  24.61 
 
 		 431 aa  106  6e-22  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_009634  Mevan_1623  2-hydroxyglutaryl-CoA dehydratase D-component  24.78 
 
 		 373 aa  106  8e-22  Methanococcus vannielii SB  Archaea  decreased coverage  0.000208392  n/a   
 
 
-
 
NC_009715  CCV52592_0873  2-hydroxyglutaryl-CoA dehydratase, D-component  25.14 
 
 		 385 aa  106  8e-22  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_013173  Dbac_1927  2-hydroxyglutaryl-CoA dehydratase D-component  25.27 
 
 		 425 aa  105  1e-21  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.756388  n/a   
 
 
-
 
NC_009634  Mevan_1356  2-hydroxyglutaryl-CoA dehydratase D-component  24.17 
 
 		 373 aa  105  1e-21  Methanococcus vannielii SB  Archaea  normal  0.0888918  n/a   
 
 
-
 
NC_008554  Sfum_3256  2-hydroxyglutaryl-CoA dehydratase, D-component  23.8 
 
 		 423 aa  102  8e-21  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013512  Sdel_2024  2-hydroxyglutaryl-CoA dehydratase D-component  22.91 
 
 		 439 aa  102  2e-20  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_007575  Suden_0273  2-hydroxyglutaryl-CoA dehydratase, D-component  23.96 
 
 		 422 aa  100  3e-20  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0427  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  26.45 
 
 		 382 aa  100  5e-20  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_0866  2-hydroxyglutaryl-CoA dehydratase, D-component  24.72 
 
 		 383 aa  100  5e-20  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.327302  normal  1 
 
 
-
 
NC_013165  Shel_25330  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  25.14 
 
 		 390 aa  99  1e-19  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  0.8257 
 
 
-
 
NC_009712  Mboo_0863  2-hydroxyglutaryl-CoA dehydratase, D-component  23.94 
 
 		 426 aa  97.8  3e-19  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.0455624  normal  1 
 
 
-
 
NC_009802  CCC13826_1134  UDP-MurNac-pentapeptide presynthetase  24.06 
 
 		 385 aa  97.1  5e-19  Campylobacter concisus 13826  Bacteria  normal  0.207036  n/a   
 
 
-
 
NC_011832  Mpal_1147  2-hydroxyglutaryl-CoA dehydratase D-component  25.97 
 
 		 393 aa  95.5  1e-18  Methanosphaerula palustris E1-9c  Archaea  normal  0.132933  normal  1 
 
 
-
 
NC_008554  Sfum_3161  2-hydroxyglutaryl-CoA dehydratase, D-component  25.57 
 
 		 382 aa  95.1  2e-18  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010814  Glov_0091  2-hydroxyglutaryl-CoA dehydratase D-component  22.65 
 
 		 429 aa  92.4  1e-17  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_1465  2-hydroxyglutaryl-CoA dehydratase D-component  24.23 
 
 		 369 aa  92  1e-17  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009253  Dred_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  22.69 
 
 		 385 aa  88.6  1e-16  Desulfotomaculum reducens MI-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013385  Adeg_1708  2-hydroxyglutaryl-CoA dehydratase D-component  24.2 
 
 		 322 aa  87.8  3e-16  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011899  Hore_16090  2-hydroxyglutaryl-CoA dehydratase D-component  24.26 
 
 		 355 aa  86.3  7e-16  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_010814  Glov_2401  2-hydroxyglutaryl-CoA dehydratase D-component  25.14 
 
 		 397 aa  86.3  7e-16  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_008340  Mlg_0785  2-hydroxyglutaryl-CoA dehydratase, D-component  26.3 
 
 		 420 aa  85.9  9e-16  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.237879  normal  1 
 
 
-
 
NC_011661  Dtur_1747  2-hydroxyglutaryl-CoA dehydratase D-component  22.35 
 
 		 339 aa  85.1  0.000000000000002  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_013204  Elen_1690  2-hydroxyglutaryl-CoA dehydratase D-component  20.77 
 
 		 424 aa  83.6  0.000000000000005  Eggerthella lenta DSM 2243  Bacteria  normal  0.531982  normal  0.740952 
 
 
-
 
NC_009483  Gura_3877  2-hydroxyglutaryl-CoA dehydratase, D-component  25.07 
 
 		 395 aa  83.6  0.000000000000005  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_008609  Ppro_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  24.86 
 
 		 413 aa  83.6  0.000000000000006  Pelobacter propionicus DSM 2379  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_26180  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  21.85 
 
 		 384 aa  79.3  0.0000000000001  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010718  Nther_1772  2-hydroxyglutaryl-CoA dehydratase D-component  26.94 
 
 		 358 aa  76.6  0.0000000000006  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.39587 
 
 
-
 
NC_009943  Dole_0930  2-hydroxyglutaryl-CoA dehydratase D-component  24.23 
 
 		 377 aa  73.9  0.000000000004  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0187897  n/a   
 
 
-
 
NC_011830  Dhaf_3454  2-hydroxyglutaryl-CoA dehydratase D-component  22.06 
 
 		 386 aa  68.2  0.0000000002  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_012918  GM21_0387  2-hydroxyglutaryl-CoA dehydratase D-component  22.47 
 
 		 327 aa  57.4  0.0000004  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_010718  Nther_1771  2-hydroxyglutaryl-CoA dehydratase D-component  21.21 
 
 		 419 aa  55.8  0.000001  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.433973 
 
 
-
 
NC_002939  GSU2925  hypothetical protein  23.73 
 
 		 324 aa  53.5  0.000006  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_007925  RPC_2056  2-hydroxyglutaryl-CoA dehydratase, D-component  22.35 
 
 		 405 aa  51.2  0.00003  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  0.727818 
 
 
-
 
NC_013552  DhcVS_532  hypothetical protein  22.71 
 
 		 336 aa  49.7  0.00007  Dehalococcoides sp. VS  Bacteria  hitchhiker  0.00368182  n/a   
 
 
-
 
NC_007644  Moth_1006  2-hydroxyglutaryl-CoA dehydratase, D-component  22.85 
 
 		 421 aa  48.1  0.0002  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.0695891  hitchhiker  0.000177823 
 
 
-
 
NC_011146  Gbem_0393  2-hydroxyglutaryl-CoA dehydratase D-component  22.13 
 
 		 327 aa  47.8  0.0003  Geobacter bemidjiensis Bem  Bacteria  normal  1  n/a   
 
 
-
 
NC_007517  Gmet_0545  hypothetical protein  21.81 
 
 		 325 aa  45.1  0.002  Geobacter metallireducens GS-15  Bacteria  normal  1  normal  1 
 
 
-
 
NC_002936  DET0591  hypothetical protein  21.63 
 
 		 339 aa  45.4  0.002  Dehalococcoides ethenogenes 195  Bacteria  normal  0.114388  n/a   
 
 
-
 
NC_010320  Teth514_1898  putative CoA-substrate-specific enzyme activase  43.86 
 
 		 539 aa  44.3  0.004  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0450  hypothetical protein  22.97 
 
 		 325 aa  43.9  0.005  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_011146  Gbem_1413  2-hydroxyglutaryl-CoA dehydratase D-component  20.61 
 
 		 415 aa  43.1  0.007  Geobacter bemidjiensis Bem  Bacteria  normal  0.657921  n/a   
 
 
-
 
NC_009455  DehaBAV1_0566  2-hydroxyglutaryl-CoA dehydratase, D-component  23.25 
 
 		 339 aa  43.1  0.008  Dehalococcoides sp. BAV1  Bacteria  hitchhiker  0.00128016  n/a   
 
 
-
 
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