92 homologs were found in PanDaTox collection
for query gene EcSMS35_4882 on replicon NC_010498
Organism: Escherichia coli SMS-3-5



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
CP001637  EcDH1_3660  2-hydroxyglutaryl-CoA dehydratase D-component  98.69 
 
 		 383 aa  791    Escherichia coli DH1  Bacteria  normal  0.814301  n/a   
 
 
-
 
CP001509  ECD_04204  predicted 2-hydroxyglutaryl-CoA dehydratase  98.69 
 
 		 383 aa  791    Escherichia coli BL21(DE3)  Bacteria  normal  0.0605066  n/a   
 
 
-
 
NC_012892  B21_04167  hypothetical protein  98.69 
 
 		 383 aa  791    Escherichia coli BL21  Bacteria  normal  0.0394396  n/a   
 
 
-
 
NC_011353  ECH74115_5849  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  98.17 
 
 		 383 aa  789    Escherichia coli O157:H7 str. EC4115  Bacteria  normal  1  normal  0.981774 
 
 
-
 
NC_010498  EcSMS35_4882  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  100 
 
 		 383 aa  798    Escherichia coli SMS-3-5  Bacteria  normal  0.30993  normal  0.992487 
 
 
-
 
NC_010468  EcolC_3728  2-hydroxyglutaryl-CoA dehydratase D-component  97.13 
 
 		 383 aa  780    Escherichia coli ATCC 8739  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009801  EcE24377A_4937  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  98.43 
 
 		 383 aa  789    Escherichia coli E24377A  Bacteria  normal  1  n/a   
 
 
-
 
NC_009800  EcHS_A4563  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  98.17 
 
 		 383 aa  788    Escherichia coli HS  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_3912  2-hydroxyglutaryl-CoA dehydratase D-component  55.94 
 
 		 384 aa  449  1e-125  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_26180  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  52.99 
 
 		 384 aa  441  1e-123  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008346  Swol_0427  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  52.24 
 
 		 382 aa  419  1e-116  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_013517  Sterm_1694  2-hydroxyglutaryl-CoA dehydratase D-component  51.98 
 
 		 382 aa  415  9.999999999999999e-116  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_014150  Bmur_0617  2-hydroxyglutaryl-CoA dehydratase D-component  49.22 
 
 		 384 aa  404  1e-111  Brachyspira murdochii DSM 12563  Bacteria  normal  1  n/a   
 
 
-
 
NC_011146  Gbem_2040  2-hydroxyglutaryl-CoA dehydratase D-component  49.07 
 
 		 401 aa  376  1e-103  Geobacter bemidjiensis Bem  Bacteria  normal  0.921137  n/a   
 
 
-
 
NC_007644  Moth_1446  2-hydroxyglutaryl-CoA dehydratase, D-component  48.12 
 
 		 381 aa  374  1e-102  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.629308  normal  0.054659 
 
 
-
 
NC_009253  Dred_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  47.63 
 
 		 385 aa  368  1e-100  Desulfotomaculum reducens MI-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009715  CCV52592_0873  2-hydroxyglutaryl-CoA dehydratase, D-component  45.12 
 
 		 385 aa  361  1e-98  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_002939  GSU2519  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  46.93 
 
 		 387 aa  361  1e-98  Geobacter sulfurreducens PCA  Bacteria  normal  0.321633  n/a   
 
 
-
 
NC_010718  Nther_0828  2-hydroxyglutaryl-CoA dehydratase D-component  44.06 
 
 		 393 aa  358  6e-98  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  hitchhiker  0.0000331904 
 
 
-
 
NC_009802  CCC13826_1134  UDP-MurNac-pentapeptide presynthetase  45.67 
 
 		 385 aa  356  5e-97  Campylobacter concisus 13826  Bacteria  normal  0.207036  n/a   
 
 
-
 
NC_002967  TDE0392  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  44.56 
 
 		 392 aa  354  2e-96  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0410  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  45.55 
 
 		 378 aa  351  1e-95  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.732282  n/a   
 
 
-
 
NC_013216  Dtox_1465  2-hydroxyglutaryl-CoA dehydratase D-component  46.2 
 
 		 369 aa  335  7e-91  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013165  Shel_25330  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  43.72 
 
 		 390 aa  329  6e-89  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  0.8257 
 
 
-
 
NC_009712  Mboo_0866  2-hydroxyglutaryl-CoA dehydratase, D-component  43.49 
 
 		 383 aa  328  7e-89  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.327302  normal  1 
 
 
-
 
NC_008554  Sfum_3161  2-hydroxyglutaryl-CoA dehydratase, D-component  43.8 
 
 		 382 aa  328  8e-89  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011769  DvMF_0986  2-hydroxyglutaryl-CoA dehydratase D-component  44 
 
 		 379 aa  325  8.000000000000001e-88  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.345407 
 
 
-
 
NC_011883  Ddes_0545  2-hydroxyglutaryl-CoA dehydratase D-component  42.97 
 
 		 379 aa  321  1.9999999999999998e-86  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_008751  Dvul_0706  2-hydroxyglutaryl-CoA dehydratase, D-component  45.38 
 
 		 380 aa  306  5.0000000000000004e-82  Desulfovibrio vulgaris DP4  Bacteria  normal  0.255737  normal  0.505258 
 
 
-
 
NC_009637  MmarC7_0081  2-hydroxyglutaryl-CoA dehydratase D-component  42.54 
 
 		 373 aa  289  5.0000000000000004e-77  Methanococcus maripaludis C7  Archaea  hitchhiker  0.00790728  hitchhiker  0.00027984 
 
 
-
 
NC_009135  MmarC5_1329  2-hydroxyglutaryl-CoA dehydratase, D-component  42.54 
 
 		 373 aa  287  2e-76  Methanococcus maripaludis C5  Archaea  normal  0.360165  n/a   
 
 
-
 
NC_009135  MmarC5_0834  2-hydroxyglutaryl-CoA dehydratase, D-component  41.69 
 
 		 373 aa  285  8e-76  Methanococcus maripaludis C5  Archaea  normal  1  n/a   
 
 
-
 
NC_009637  MmarC7_1346  2-hydroxyglutaryl-CoA dehydratase D-component  42.25 
 
 		 373 aa  283  3.0000000000000004e-75  Methanococcus maripaludis C7  Archaea  normal  0.922776  normal  0.0249494 
 
 
-
 
NC_009975  MmarC6_1821  2-hydroxyglutaryl-CoA dehydratase D-component  41.69 
 
 		 373 aa  283  4.0000000000000003e-75  Methanococcus maripaludis C6  Archaea  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_2825  2-hydroxyglutaryl-CoA dehydratase D-component  40.21 
 
 		 368 aa  282  6.000000000000001e-75  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007519  Dde_0090  2-hydroxyglutaryl-CoA dehydratase, beta subunit-like  41.55 
 
 		 426 aa  282  7.000000000000001e-75  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_009975  MmarC6_0607  2-hydroxyglutaryl-CoA dehydratase D-component  41.69 
 
 		 373 aa  278  1e-73  Methanococcus maripaludis C6  Archaea  normal  0.422107  n/a   
 
 
-
 
NC_009635  Maeo_1346  2-hydroxyglutaryl-CoA dehydratase D-component  41.41 
 
 		 372 aa  276  6e-73  Methanococcus aeolicus Nankai-3  Archaea  normal  0.120946  n/a   
 
 
-
 
NC_009634  Mevan_1356  2-hydroxyglutaryl-CoA dehydratase D-component  38.34 
 
 		 373 aa  273  3e-72  Methanococcus vannielii SB  Archaea  normal  0.0888918  n/a   
 
 
-
 
NC_013216  Dtox_0119  2-hydroxyglutaryl-CoA dehydratase D-component  41.21 
 
 		 424 aa  271  2e-71  Desulfotomaculum acetoxidans DSM 771  Bacteria  hitchhiker  0.000350126  normal  0.0170821 
 
 
-
 
NC_013173  Dbac_1927  2-hydroxyglutaryl-CoA dehydratase D-component  39.12 
 
 		 425 aa  266  2.9999999999999995e-70  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.756388  n/a   
 
 
-
 
NC_008554  Sfum_3256  2-hydroxyglutaryl-CoA dehydratase, D-component  38.9 
 
 		 423 aa  266  5.999999999999999e-70  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011832  Mpal_1311  2-hydroxyglutaryl-CoA dehydratase D-component  37.05 
 
 		 388 aa  264  2e-69  Methanosphaerula palustris E1-9c  Archaea  normal  0.522959  normal  1 
 
 
-
 
NC_013385  Adeg_0387  2-hydroxyglutaryl-CoA dehydratase D-component  38.02 
 
 		 426 aa  259  5.0000000000000005e-68  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_009634  Mevan_1623  2-hydroxyglutaryl-CoA dehydratase D-component  39.83 
 
 		 373 aa  258  1e-67  Methanococcus vannielii SB  Archaea  decreased coverage  0.000208392  n/a   
 
 
-
 
NC_010814  Glov_0091  2-hydroxyglutaryl-CoA dehydratase D-component  37.66 
 
 		 429 aa  256  5e-67  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_013522  Taci_0254  2-hydroxyglutaryl-CoA dehydratase D-component  39.95 
 
 		 423 aa  256  7e-67  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1418  2-hydroxyglutaryl-CoA dehydratase, D-component  37.82 
 
 		 436 aa  253  4.0000000000000004e-66  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00133287  normal  0.906732 
 
 
-
 
NC_002939  GSU2944  (R)-2-hydroxyglutaryl-CoA dehydratase alpha-subunit, putative  38.04 
 
 		 431 aa  246  4e-64  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_002967  TDE0389  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  38.17 
 
 		 412 aa  246  6e-64  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_25470  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  37.98 
 
 		 425 aa  241  1e-62  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008346  Swol_0412  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  37.12 
 
 		 424 aa  237  2e-61  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_013512  Sdel_2024  2-hydroxyglutaryl-CoA dehydratase D-component  34.99 
 
 		 439 aa  236  7e-61  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_013170  Ccur_11360  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  38.48 
 
 		 426 aa  235  8e-61  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.390545  normal  0.8731 
 
 
-
 
NC_013204  Elen_1690  2-hydroxyglutaryl-CoA dehydratase D-component  38.42 
 
 		 424 aa  234  2.0000000000000002e-60  Eggerthella lenta DSM 2243  Bacteria  normal  0.531982  normal  0.740952 
 
 
-
 
NC_009712  Mboo_0863  2-hydroxyglutaryl-CoA dehydratase, D-component  33.33 
 
 		 426 aa  223  3e-57  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.0455624  normal  1 
 
 
-
 
NC_011830  Dhaf_1101  2-hydroxyglutaryl-CoA dehydratase D-component  27.69 
 
 		 379 aa  141  1.9999999999999998e-32  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_008340  Mlg_0785  2-hydroxyglutaryl-CoA dehydratase, D-component  31.78 
 
 		 420 aa  138  1e-31  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.237879  normal  1 
 
 
-
 
NC_007925  RPC_2055  2-hydroxyglutaryl-CoA dehydratase, D-component  29.18 
 
 		 376 aa  127  2.0000000000000002e-28  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.574959  normal  0.736744 
 
 
-
 
NC_011832  Mpal_1147  2-hydroxyglutaryl-CoA dehydratase D-component  25.61 
 
 		 393 aa  123  5e-27  Methanosphaerula palustris E1-9c  Archaea  normal  0.132933  normal  1 
 
 
-
 
NC_007575  Suden_0273  2-hydroxyglutaryl-CoA dehydratase, D-component  28.37 
 
 		 422 aa  120  3.9999999999999996e-26  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  1  n/a   
 
 
-
 
NC_008609  Ppro_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  27.98 
 
 		 413 aa  119  9.999999999999999e-26  Pelobacter propionicus DSM 2379  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_2769  2-hydroxyglutaryl-CoA dehydratase D-component  25.33 
 
 		 379 aa  95.9  1e-18  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_0891  2-hydroxyglutaryl-CoA dehydratase D-component  26.63 
 
 		 373 aa  92  2e-17  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_3877  2-hydroxyglutaryl-CoA dehydratase, D-component  23.84 
 
 		 395 aa  89  1e-16  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_2774  2-hydroxyglutaryl-CoA dehydratase D-component  24.05 
 
 		 376 aa  84.3  0.000000000000003  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1771  2-hydroxyglutaryl-CoA dehydratase D-component  22.85 
 
 		 419 aa  79.7  0.00000000000008  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.433973 
 
 
-
 
NC_009943  Dole_1686  2-hydroxyglutaryl-CoA dehydratase D-component  22.9 
 
 		 370 aa  75.1  0.000000000002  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0274681  n/a   
 
 
-
 
NC_011830  Dhaf_3454  2-hydroxyglutaryl-CoA dehydratase D-component  25.07 
 
 		 386 aa  73.6  0.000000000005  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1007  2-hydroxyglutaryl-CoA dehydratase, D-component  23.96 
 
 		 349 aa  71.2  0.00000000003  Moorella thermoacetica ATCC 39073  Bacteria  decreased coverage  0.0000000530359  hitchhiker  0.000167288 
 
 
-
 
NC_011899  Hore_16080  2-hydroxyglutaryl-CoA dehydratase D-component  23.06 
 
 		 426 aa  69.7  0.00000000009  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_011899  Hore_16090  2-hydroxyglutaryl-CoA dehydratase D-component  22.66 
 
 		 355 aa  67  0.0000000005  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_007958  RPD_1538  benzoyl-CoA reductase, subunit C  22.19 
 
 		 394 aa  63.5  0.000000005  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.130058  normal  1 
 
 
-
 
NC_013385  Adeg_1708  2-hydroxyglutaryl-CoA dehydratase D-component  24.38 
 
 		 322 aa  62.4  0.00000001  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_007925  RPC_1029  benzoyl-CoA reductase, subunit C  20.39 
 
 		 394 aa  60.5  0.00000005  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011661  Dtur_1747  2-hydroxyglutaryl-CoA dehydratase D-component  19.6 
 
 		 339 aa  60.5  0.00000005  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_011004  Rpal_0724  benzoyl-CoA reductase, subunit C  20.99 
 
 		 394 aa  60.5  0.00000006  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.377082  n/a   
 
 
-
 
NC_010718  Nther_1772  2-hydroxyglutaryl-CoA dehydratase D-component  21.33 
 
 		 358 aa  60.1  0.00000007  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.39587 
 
 
-
 
NC_011662  Tmz1t_2951  benzoyl-CoA reductase, subunit C  19.2 
 
 		 386 aa  58.5  0.0000002  Thauera sp. MZ1T  Bacteria  normal  0.689086  n/a   
 
 
-
 
NC_011832  Mpal_1137  2-hydroxyglutaryl-CoA dehydratase D-component  26.55 
 
 		 494 aa  53.1  0.000009  Methanosphaerula palustris E1-9c  Archaea  normal  0.417243  normal  1 
 
 
-
 
NC_010814  Glov_2401  2-hydroxyglutaryl-CoA dehydratase D-component  22.73 
 
 		 397 aa  52  0.00002  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1006  2-hydroxyglutaryl-CoA dehydratase, D-component  21.76 
 
 		 421 aa  50.4  0.00005  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.0695891  hitchhiker  0.000177823 
 
 
-
 
NC_011832  Mpal_1146  2-hydroxyglutaryl-CoA dehydratase D-component  25.44 
 
 		 501 aa  47.4  0.0005  Methanosphaerula palustris E1-9c  Archaea  normal  0.114062  normal  1 
 
 
-
 
NC_010320  Teth514_1899  2-hydroxyglutaryl-CoA dehydratase, D-component  20 
 
 		 416 aa  46.2  0.001  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_3878  2-hydroxyglutaryl-CoA dehydratase, D-component  26.54 
 
 		 472 aa  46.2  0.001  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_010320  Teth514_1898  putative CoA-substrate-specific enzyme activase  20.69 
 
 		 539 aa  45.8  0.001  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_1135  2-hydroxyglutaryl-CoA dehydratase D-component  25.17 
 
 		 494 aa  45.1  0.002  Methanosphaerula palustris E1-9c  Archaea  normal  1  normal  0.207631 
 
 
-
 
NC_011662  Tmz1t_2950  benzoyl-CoA reductase, subunit B  21.38 
 
 		 432 aa  45.1  0.002  Thauera sp. MZ1T  Bacteria  normal  1  n/a   
 
 
-
 
NC_010424  Daud_1507  2-hydroxyglutaryl-CoA dehydratase, D-component  23.8 
 
 		 326 aa  43.9  0.005  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_2775  2-hydroxyglutaryl-CoA dehydratase D-component  22.83 
 
 		 469 aa  43.5  0.006  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_0931  2-hydroxyglutaryl-CoA dehydratase D-component  29.41 
 
 		 419 aa  43.1  0.008  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_002939  GSU2925  hypothetical protein  24.58 
 
 		 324 aa  43.1  0.008  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
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