90 homologs were found in PanDaTox collection
for query gene TDE0392 on replicon NC_002967
Organism: Treponema denticola ATCC 35405



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_002967  TDE0392  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  100 
 
 		 392 aa  813    Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0427  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  53.51 
 
 		 382 aa  429  1e-119  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_3912  2-hydroxyglutaryl-CoA dehydratase D-component  48.43 
 
 		 384 aa  387  1e-106  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_014150  Bmur_0617  2-hydroxyglutaryl-CoA dehydratase D-component  48.44 
 
 		 384 aa  377  1e-103  Brachyspira murdochii DSM 12563  Bacteria  normal  1  n/a   
 
 
-
 
NC_013517  Sterm_1694  2-hydroxyglutaryl-CoA dehydratase D-component  47.12 
 
 		 382 aa  377  1e-103  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0410  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  46.35 
 
 		 378 aa  367  1e-100  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.732282  n/a   
 
 
-
 
NC_007644  Moth_1446  2-hydroxyglutaryl-CoA dehydratase, D-component  45.45 
 
 		 381 aa  355  7.999999999999999e-97  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.629308  normal  0.054659 
 
 
-
 
NC_013165  Shel_26180  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  44.16 
 
 		 384 aa  355  1e-96  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010468  EcolC_3728  2-hydroxyglutaryl-CoA dehydratase D-component  44.82 
 
 		 383 aa  355  1e-96  Escherichia coli ATCC 8739  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010498  EcSMS35_4882  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  44.56 
 
 		 383 aa  354  2e-96  Escherichia coli SMS-3-5  Bacteria  normal  0.30993  normal  0.992487 
 
 
-
 
CP001637  EcDH1_3660  2-hydroxyglutaryl-CoA dehydratase D-component  44.56 
 
 		 383 aa  353  2.9999999999999997e-96  Escherichia coli DH1  Bacteria  normal  0.814301  n/a   
 
 
-
 
NC_012892  B21_04167  hypothetical protein  44.56 
 
 		 383 aa  353  2.9999999999999997e-96  Escherichia coli BL21  Bacteria  normal  0.0394396  n/a   
 
 
-
 
CP001509  ECD_04204  predicted 2-hydroxyglutaryl-CoA dehydratase  44.56 
 
 		 383 aa  353  2.9999999999999997e-96  Escherichia coli BL21(DE3)  Bacteria  normal  0.0605066  n/a   
 
 
-
 
NC_011146  Gbem_2040  2-hydroxyglutaryl-CoA dehydratase D-component  46.09 
 
 		 401 aa  352  5e-96  Geobacter bemidjiensis Bem  Bacteria  normal  0.921137  n/a   
 
 
-
 
NC_009801  EcE24377A_4937  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  44.56 
 
 		 383 aa  352  5e-96  Escherichia coli E24377A  Bacteria  normal  1  n/a   
 
 
-
 
NC_009800  EcHS_A4563  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  44.16 
 
 		 383 aa  352  8e-96  Escherichia coli HS  Bacteria  normal  1  n/a   
 
 
-
 
NC_011353  ECH74115_5849  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  44.56 
 
 		 383 aa  351  1e-95  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  1  normal  0.981774 
 
 
-
 
NC_002939  GSU2519  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  45.43 
 
 		 387 aa  348  7e-95  Geobacter sulfurreducens PCA  Bacteria  normal  0.321633  n/a   
 
 
-
 
NC_013165  Shel_25330  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  45.03 
 
 		 390 aa  347  3e-94  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  0.8257 
 
 
-
 
NC_009253  Dred_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  41.84 
 
 		 385 aa  333  3e-90  Desulfotomaculum reducens MI-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008554  Sfum_3161  2-hydroxyglutaryl-CoA dehydratase, D-component  44.62 
 
 		 382 aa  333  4e-90  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010718  Nther_0828  2-hydroxyglutaryl-CoA dehydratase D-component  42.78 
 
 		 393 aa  318  7.999999999999999e-86  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  hitchhiker  0.0000331904 
 
 
-
 
NC_009712  Mboo_0866  2-hydroxyglutaryl-CoA dehydratase, D-component  42.23 
 
 		 383 aa  313  3.9999999999999997e-84  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.327302  normal  1 
 
 
-
 
NC_009715  CCV52592_0873  2-hydroxyglutaryl-CoA dehydratase, D-component  40.16 
 
 		 385 aa  310  2e-83  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_009802  CCC13826_1134  UDP-MurNac-pentapeptide presynthetase  40.92 
 
 		 385 aa  308  8e-83  Campylobacter concisus 13826  Bacteria  normal  0.207036  n/a   
 
 
-
 
NC_013216  Dtox_1465  2-hydroxyglutaryl-CoA dehydratase D-component  41.35 
 
 		 369 aa  308  2.0000000000000002e-82  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011769  DvMF_0986  2-hydroxyglutaryl-CoA dehydratase D-component  41.25 
 
 		 379 aa  305  7e-82  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.345407 
 
 
-
 
NC_008751  Dvul_0706  2-hydroxyglutaryl-CoA dehydratase, D-component  42.89 
 
 		 380 aa  302  8.000000000000001e-81  Desulfovibrio vulgaris DP4  Bacteria  normal  0.255737  normal  0.505258 
 
 
-
 
NC_013216  Dtox_2825  2-hydroxyglutaryl-CoA dehydratase D-component  40.32 
 
 		 368 aa  286  4e-76  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011883  Ddes_0545  2-hydroxyglutaryl-CoA dehydratase D-component  39.15 
 
 		 379 aa  285  1.0000000000000001e-75  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_0119  2-hydroxyglutaryl-CoA dehydratase D-component  40.1 
 
 		 424 aa  280  3e-74  Desulfotomaculum acetoxidans DSM 771  Bacteria  hitchhiker  0.000350126  normal  0.0170821 
 
 
-
 
NC_011832  Mpal_1311  2-hydroxyglutaryl-CoA dehydratase D-component  37.66 
 
 		 388 aa  276  5e-73  Methanosphaerula palustris E1-9c  Archaea  normal  0.522959  normal  1 
 
 
-
 
NC_009135  MmarC5_0834  2-hydroxyglutaryl-CoA dehydratase, D-component  40.48 
 
 		 373 aa  275  7e-73  Methanococcus maripaludis C5  Archaea  normal  1  n/a   
 
 
-
 
NC_009634  Mevan_1356  2-hydroxyglutaryl-CoA dehydratase D-component  41.27 
 
 		 373 aa  275  9e-73  Methanococcus vannielii SB  Archaea  normal  0.0888918  n/a   
 
 
-
 
NC_009637  MmarC7_0081  2-hydroxyglutaryl-CoA dehydratase D-component  39.68 
 
 		 373 aa  272  8.000000000000001e-72  Methanococcus maripaludis C7  Archaea  hitchhiker  0.00790728  hitchhiker  0.00027984 
 
 
-
 
NC_009975  MmarC6_1821  2-hydroxyglutaryl-CoA dehydratase D-component  39.42 
 
 		 373 aa  269  5.9999999999999995e-71  Methanococcus maripaludis C6  Archaea  normal  1  n/a   
 
 
-
 
NC_009975  MmarC6_0607  2-hydroxyglutaryl-CoA dehydratase D-component  39.95 
 
 		 373 aa  266  4e-70  Methanococcus maripaludis C6  Archaea  normal  0.422107  n/a   
 
 
-
 
NC_009135  MmarC5_1329  2-hydroxyglutaryl-CoA dehydratase, D-component  40.21 
 
 		 373 aa  265  8e-70  Methanococcus maripaludis C5  Archaea  normal  0.360165  n/a   
 
 
-
 
NC_009637  MmarC7_1346  2-hydroxyglutaryl-CoA dehydratase D-component  39.42 
 
 		 373 aa  264  2e-69  Methanococcus maripaludis C7  Archaea  normal  0.922776  normal  0.0249494 
 
 
-
 
NC_013385  Adeg_0387  2-hydroxyglutaryl-CoA dehydratase D-component  36.92 
 
 		 426 aa  260  3e-68  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_009635  Maeo_1346  2-hydroxyglutaryl-CoA dehydratase D-component  38.64 
 
 		 372 aa  256  6e-67  Methanococcus aeolicus Nankai-3  Archaea  normal  0.120946  n/a   
 
 
-
 
NC_007644  Moth_1418  2-hydroxyglutaryl-CoA dehydratase, D-component  35.57 
 
 		 436 aa  254  2.0000000000000002e-66  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00133287  normal  0.906732 
 
 
-
 
NC_008554  Sfum_3256  2-hydroxyglutaryl-CoA dehydratase, D-component  36.6 
 
 		 423 aa  249  6e-65  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009634  Mevan_1623  2-hydroxyglutaryl-CoA dehydratase D-component  38.04 
 
 		 373 aa  248  2e-64  Methanococcus vannielii SB  Archaea  decreased coverage  0.000208392  n/a   
 
 
-
 
NC_013522  Taci_0254  2-hydroxyglutaryl-CoA dehydratase D-component  37.02 
 
 		 423 aa  247  3e-64  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0412  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  36.27 
 
 		 424 aa  246  4e-64  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_013173  Dbac_1927  2-hydroxyglutaryl-CoA dehydratase D-component  35.47 
 
 		 425 aa  239  8e-62  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.756388  n/a   
 
 
-
 
NC_013512  Sdel_2024  2-hydroxyglutaryl-CoA dehydratase D-component  33.67 
 
 		 439 aa  239  9e-62  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_002939  GSU2944  (R)-2-hydroxyglutaryl-CoA dehydratase alpha-subunit, putative  34.04 
 
 		 431 aa  236  4e-61  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_013204  Elen_1690  2-hydroxyglutaryl-CoA dehydratase D-component  36.61 
 
 		 424 aa  234  2.0000000000000002e-60  Eggerthella lenta DSM 2243  Bacteria  normal  0.531982  normal  0.740952 
 
 
-
 
NC_013170  Ccur_11360  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  37.11 
 
 		 426 aa  231  2e-59  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.390545  normal  0.8731 
 
 
-
 
NC_010814  Glov_0091  2-hydroxyglutaryl-CoA dehydratase D-component  37.08 
 
 		 429 aa  231  2e-59  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_25470  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  37.29 
 
 		 425 aa  229  4e-59  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_002967  TDE0389  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  34.79 
 
 		 412 aa  226  5.0000000000000005e-58  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_007519  Dde_0090  2-hydroxyglutaryl-CoA dehydratase, beta subunit-like  33.6 
 
 		 426 aa  226  6e-58  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_0863  2-hydroxyglutaryl-CoA dehydratase, D-component  34.95 
 
 		 426 aa  223  4.9999999999999996e-57  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.0455624  normal  1 
 
 
-
 
NC_007575  Suden_0273  2-hydroxyglutaryl-CoA dehydratase, D-component  29.64 
 
 		 422 aa  156  5.0000000000000005e-37  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  1  n/a   
 
 
-
 
NC_008340  Mlg_0785  2-hydroxyglutaryl-CoA dehydratase, D-component  26.67 
 
 		 420 aa  138  2e-31  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.237879  normal  1 
 
 
-
 
NC_011832  Mpal_1147  2-hydroxyglutaryl-CoA dehydratase D-component  24.94 
 
 		 393 aa  129  8.000000000000001e-29  Methanosphaerula palustris E1-9c  Archaea  normal  0.132933  normal  1 
 
 
-
 
NC_008609  Ppro_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  27.75 
 
 		 413 aa  117  3e-25  Pelobacter propionicus DSM 2379  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_1101  2-hydroxyglutaryl-CoA dehydratase D-component  24.05 
 
 		 379 aa  116  6.9999999999999995e-25  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_3877  2-hydroxyglutaryl-CoA dehydratase, D-component  25.37 
 
 		 395 aa  109  7.000000000000001e-23  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_007925  RPC_2055  2-hydroxyglutaryl-CoA dehydratase, D-component  24.93 
 
 		 376 aa  104  2e-21  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.574959  normal  0.736744 
 
 
-
 
NC_009943  Dole_2769  2-hydroxyglutaryl-CoA dehydratase D-component  25.92 
 
 		 379 aa  97.8  3e-19  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_2774  2-hydroxyglutaryl-CoA dehydratase D-component  23.33 
 
 		 376 aa  88.6  2e-16  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_013385  Adeg_1708  2-hydroxyglutaryl-CoA dehydratase D-component  23.61 
 
 		 322 aa  87.4  4e-16  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011661  Dtur_1747  2-hydroxyglutaryl-CoA dehydratase D-component  25 
 
 		 339 aa  84.3  0.000000000000003  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1007  2-hydroxyglutaryl-CoA dehydratase, D-component  24.04 
 
 		 349 aa  77.8  0.0000000000003  Moorella thermoacetica ATCC 39073  Bacteria  decreased coverage  0.0000000530359  hitchhiker  0.000167288 
 
 
-
 
NC_009943  Dole_0891  2-hydroxyglutaryl-CoA dehydratase D-component  23.44 
 
 		 373 aa  77.8  0.0000000000003  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_3454  2-hydroxyglutaryl-CoA dehydratase D-component  23.18 
 
 		 386 aa  75.9  0.000000000001  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1772  2-hydroxyglutaryl-CoA dehydratase D-component  22.25 
 
 		 358 aa  73.2  0.000000000007  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.39587 
 
 
-
 
NC_011899  Hore_16090  2-hydroxyglutaryl-CoA dehydratase D-component  24.59 
 
 		 355 aa  72.4  0.00000000001  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1771  2-hydroxyglutaryl-CoA dehydratase D-component  21.87 
 
 		 419 aa  67  0.0000000005  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.433973 
 
 
-
 
NC_009943  Dole_1686  2-hydroxyglutaryl-CoA dehydratase D-component  23.8 
 
 		 370 aa  67  0.0000000006  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0274681  n/a   
 
 
-
 
NC_011899  Hore_16080  2-hydroxyglutaryl-CoA dehydratase D-component  23.34 
 
 		 426 aa  65.9  0.000000001  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_011662  Tmz1t_2951  benzoyl-CoA reductase, subunit C  21.84 
 
 		 386 aa  65.5  0.000000002  Thauera sp. MZ1T  Bacteria  normal  0.689086  n/a   
 
 
-
 
NC_007644  Moth_1006  2-hydroxyglutaryl-CoA dehydratase, D-component  22.01 
 
 		 421 aa  63.5  0.000000006  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.0695891  hitchhiker  0.000177823 
 
 
-
 
NC_007925  RPC_1029  benzoyl-CoA reductase, subunit C  23.12 
 
 		 394 aa  58.2  0.0000002  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011004  Rpal_0724  benzoyl-CoA reductase, subunit C  22.13 
 
 		 394 aa  58.9  0.0000002  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.377082  n/a   
 
 
-
 
NC_010814  Glov_2401  2-hydroxyglutaryl-CoA dehydratase D-component  23.41 
 
 		 397 aa  57.4  0.0000005  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_007925  RPC_2056  2-hydroxyglutaryl-CoA dehydratase, D-component  21.55 
 
 		 405 aa  56.6  0.0000006  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  0.727818 
 
 
-
 
NC_012034  Athe_0199  2-hydroxyglutaryl-CoA dehydratase D-component  22.16 
 
 		 416 aa  54.7  0.000002  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.00000602439  n/a   
 
 
-
 
NC_007958  RPD_1538  benzoyl-CoA reductase, subunit C  22.03 
 
 		 394 aa  55.1  0.000002  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.130058  normal  1 
 
 
-
 
NC_011662  Tmz1t_2950  benzoyl-CoA reductase, subunit B  23.57 
 
 		 432 aa  53.1  0.000008  Thauera sp. MZ1T  Bacteria  normal  1  n/a   
 
 
-
 
NC_009012  Cthe_3103  2-hydroxyglutaryl-CoA dehydratase, D-component  25.34 
 
 		 328 aa  48.5  0.0002  Clostridium thermocellum ATCC 27405  Bacteria  normal  1  n/a   
 
 
-
 
NC_011661  Dtur_1746  2-hydroxyglutaryl-CoA dehydratase D-component  22.18 
 
 		 408 aa  45.8  0.001  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_010320  Teth514_1899  2-hydroxyglutaryl-CoA dehydratase, D-component  21.96 
 
 		 416 aa  44.3  0.003  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_012034  Athe_0200  CoA-substrate-specific enzyme activase  24.49 
 
 		 539 aa  44.7  0.003  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.00000427749  n/a   
 
 
-
 
NC_009483  Gura_0485  2-hydroxyglutaryl-CoA dehydratase, D-component  22.95 
 
 		 333 aa  44.3  0.004  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011004  Rpal_0725  benzoyl-CoA reductase, subunit B  20.15 
 
 		 436 aa  42.7  0.01  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.0743165  n/a   
 
 
-
 
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