88 homologs were found in PanDaTox collection
for query gene Dred_1278 on replicon NC_009253
Organism: Desulfotomaculum reducens MI-1



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009253  Dred_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  100 
 
 		 385 aa  799    Desulfotomaculum reducens MI-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_1465  2-hydroxyglutaryl-CoA dehydratase D-component  59.51 
 
 		 369 aa  468  9.999999999999999e-131  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007644  Moth_1446  2-hydroxyglutaryl-CoA dehydratase, D-component  54.31 
 
 		 381 aa  451  1.0000000000000001e-126  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.629308  normal  0.054659 
 
 
-
 
NC_011146  Gbem_2040  2-hydroxyglutaryl-CoA dehydratase D-component  56.33 
 
 		 401 aa  445  1.0000000000000001e-124  Geobacter bemidjiensis Bem  Bacteria  normal  0.921137  n/a   
 
 
-
 
NC_002939  GSU2519  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  52.69 
 
 		 387 aa  433  1e-120  Geobacter sulfurreducens PCA  Bacteria  normal  0.321633  n/a   
 
 
-
 
NC_008346  Swol_0410  (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative  49.61 
 
 		 378 aa  402  1e-111  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.732282  n/a   
 
 
-
 
NC_011769  DvMF_0986  2-hydroxyglutaryl-CoA dehydratase D-component  49.6 
 
 		 379 aa  401  1e-111  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.345407 
 
 
-
 
NC_008554  Sfum_3161  2-hydroxyglutaryl-CoA dehydratase, D-component  48.69 
 
 		 382 aa  396  1e-109  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010718  Nther_0828  2-hydroxyglutaryl-CoA dehydratase D-component  45.95 
 
 		 393 aa  393  1e-108  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  hitchhiker  0.0000331904 
 
 
-
 
NC_011883  Ddes_0545  2-hydroxyglutaryl-CoA dehydratase D-component  50.14 
 
 		 379 aa  391  1e-108  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_008751  Dvul_0706  2-hydroxyglutaryl-CoA dehydratase, D-component  51.76 
 
 		 380 aa  390  1e-107  Desulfovibrio vulgaris DP4  Bacteria  normal  0.255737  normal  0.505258 
 
 
-
 
NC_013517  Sterm_1694  2-hydroxyglutaryl-CoA dehydratase D-component  48.42 
 
 		 382 aa  376  1e-103  Sebaldella termitidis ATCC 33386  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0427  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  48.16 
 
 		 382 aa  375  1e-102  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_012892  B21_04167  hypothetical protein  47.89 
 
 		 383 aa  369  1e-101  Escherichia coli BL21  Bacteria  normal  0.0394396  n/a   
 
 
-
 
CP001509  ECD_04204  predicted 2-hydroxyglutaryl-CoA dehydratase  47.89 
 
 		 383 aa  369  1e-101  Escherichia coli BL21(DE3)  Bacteria  normal  0.0605066  n/a   
 
 
-
 
NC_009712  Mboo_0866  2-hydroxyglutaryl-CoA dehydratase, D-component  45.29 
 
 		 383 aa  371  1e-101  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.327302  normal  1 
 
 
-
 
CP001637  EcDH1_3660  2-hydroxyglutaryl-CoA dehydratase D-component  47.89 
 
 		 383 aa  369  1e-101  Escherichia coli DH1  Bacteria  normal  0.814301  n/a   
 
 
-
 
NC_011353  ECH74115_5849  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  48.16 
 
 		 383 aa  367  1e-100  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  1  normal  0.981774 
 
 
-
 
NC_010498  EcSMS35_4882  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  47.63 
 
 		 383 aa  368  1e-100  Escherichia coli SMS-3-5  Bacteria  normal  0.30993  normal  0.992487 
 
 
-
 
NC_010468  EcolC_3728  2-hydroxyglutaryl-CoA dehydratase D-component  47.89 
 
 		 383 aa  367  1e-100  Escherichia coli ATCC 8739  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009801  EcE24377A_4937  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  47.89 
 
 		 383 aa  368  1e-100  Escherichia coli E24377A  Bacteria  normal  1  n/a   
 
 
-
 
NC_009800  EcHS_A4563  putative 2-hydroxyglutaryl-CoA dehydratase, D-component  47.89 
 
 		 383 aa  367  1e-100  Escherichia coli HS  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_3912  2-hydroxyglutaryl-CoA dehydratase D-component  46.58 
 
 		 384 aa  363  2e-99  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_014150  Bmur_0617  2-hydroxyglutaryl-CoA dehydratase D-component  47.11 
 
 		 384 aa  359  5e-98  Brachyspira murdochii DSM 12563  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_26180  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  46.84 
 
 		 384 aa  351  2e-95  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013216  Dtox_2825  2-hydroxyglutaryl-CoA dehydratase D-component  48.41 
 
 		 368 aa  345  8e-94  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  1  normal  1 
 
 
-
 
NC_002967  TDE0392  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  41.84 
 
 		 392 aa  333  3e-90  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_25330  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  42.15 
 
 		 390 aa  328  7e-89  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  0.8257 
 
 
-
 
NC_009715  CCV52592_0873  2-hydroxyglutaryl-CoA dehydratase, D-component  42.86 
 
 		 385 aa  328  1.0000000000000001e-88  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_009802  CCC13826_1134  UDP-MurNac-pentapeptide presynthetase  42.31 
 
 		 385 aa  326  5e-88  Campylobacter concisus 13826  Bacteria  normal  0.207036  n/a   
 
 
-
 
NC_009637  MmarC7_0081  2-hydroxyglutaryl-CoA dehydratase D-component  42.86 
 
 		 373 aa  305  7e-82  Methanococcus maripaludis C7  Archaea  hitchhiker  0.00790728  hitchhiker  0.00027984 
 
 
-
 
NC_009135  MmarC5_0834  2-hydroxyglutaryl-CoA dehydratase, D-component  42.22 
 
 		 373 aa  301  2e-80  Methanococcus maripaludis C5  Archaea  normal  1  n/a   
 
 
-
 
NC_009975  MmarC6_1821  2-hydroxyglutaryl-CoA dehydratase D-component  41.8 
 
 		 373 aa  297  2e-79  Methanococcus maripaludis C6  Archaea  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_1311  2-hydroxyglutaryl-CoA dehydratase D-component  39.07 
 
 		 388 aa  284  2.0000000000000002e-75  Methanosphaerula palustris E1-9c  Archaea  normal  0.522959  normal  1 
 
 
-
 
NC_009635  Maeo_1346  2-hydroxyglutaryl-CoA dehydratase D-component  41.78 
 
 		 372 aa  276  5e-73  Methanococcus aeolicus Nankai-3  Archaea  normal  0.120946  n/a   
 
 
-
 
NC_009634  Mevan_1356  2-hydroxyglutaryl-CoA dehydratase D-component  39.22 
 
 		 373 aa  272  7e-72  Methanococcus vannielii SB  Archaea  normal  0.0888918  n/a   
 
 
-
 
NC_013522  Taci_0254  2-hydroxyglutaryl-CoA dehydratase D-component  38.08 
 
 		 423 aa  271  1e-71  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  1  n/a   
 
 
-
 
NC_008346  Swol_0412  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  36.6 
 
 		 424 aa  270  2e-71  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_25470  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  36.86 
 
 		 425 aa  268  1e-70  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009135  MmarC5_1329  2-hydroxyglutaryl-CoA dehydratase, D-component  40.56 
 
 		 373 aa  267  2e-70  Methanococcus maripaludis C5  Archaea  normal  0.360165  n/a   
 
 
-
 
NC_013385  Adeg_0387  2-hydroxyglutaryl-CoA dehydratase D-component  36.86 
 
 		 426 aa  267  2e-70  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_009637  MmarC7_1346  2-hydroxyglutaryl-CoA dehydratase D-component  40.56 
 
 		 373 aa  267  2.9999999999999995e-70  Methanococcus maripaludis C7  Archaea  normal  0.922776  normal  0.0249494 
 
 
-
 
NC_009975  MmarC6_0607  2-hydroxyglutaryl-CoA dehydratase D-component  40 
 
 		 373 aa  265  8e-70  Methanococcus maripaludis C6  Archaea  normal  0.422107  n/a   
 
 
-
 
NC_013170  Ccur_11360  Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB  37.76 
 
 		 426 aa  265  1e-69  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.390545  normal  0.8731 
 
 
-
 
NC_002939  GSU2944  (R)-2-hydroxyglutaryl-CoA dehydratase alpha-subunit, putative  36.76 
 
 		 431 aa  259  4e-68  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_002967  TDE0389  (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative  35.73 
 
 		 412 aa  257  2e-67  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_0119  2-hydroxyglutaryl-CoA dehydratase D-component  37.98 
 
 		 424 aa  257  2e-67  Desulfotomaculum acetoxidans DSM 771  Bacteria  hitchhiker  0.000350126  normal  0.0170821 
 
 
-
 
NC_013204  Elen_1690  2-hydroxyglutaryl-CoA dehydratase D-component  35.9 
 
 		 424 aa  255  9e-67  Eggerthella lenta DSM 2243  Bacteria  normal  0.531982  normal  0.740952 
 
 
-
 
NC_008554  Sfum_3256  2-hydroxyglutaryl-CoA dehydratase, D-component  35.71 
 
 		 423 aa  253  4.0000000000000004e-66  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007644  Moth_1418  2-hydroxyglutaryl-CoA dehydratase, D-component  35.92 
 
 		 436 aa  253  5.000000000000001e-66  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00133287  normal  0.906732 
 
 
-
 
NC_007519  Dde_0090  2-hydroxyglutaryl-CoA dehydratase, beta subunit-like  37.53 
 
 		 426 aa  250  3e-65  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_013512  Sdel_2024  2-hydroxyglutaryl-CoA dehydratase D-component  34.44 
 
 		 439 aa  248  2e-64  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_013173  Dbac_1927  2-hydroxyglutaryl-CoA dehydratase D-component  36.65 
 
 		 425 aa  244  3e-63  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.756388  n/a   
 
 
-
 
NC_010814  Glov_0091  2-hydroxyglutaryl-CoA dehydratase D-component  36.76 
 
 		 429 aa  244  3e-63  Geobacter lovleyi SZ  Bacteria  normal  1  n/a   
 
 
-
 
NC_009634  Mevan_1623  2-hydroxyglutaryl-CoA dehydratase D-component  38.79 
 
 		 373 aa  242  7e-63  Methanococcus vannielii SB  Archaea  decreased coverage  0.000208392  n/a   
 
 
-
 
NC_009712  Mboo_0863  2-hydroxyglutaryl-CoA dehydratase, D-component  34.96 
 
 		 426 aa  238  9e-62  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.0455624  normal  1 
 
 
-
 
NC_011830  Dhaf_1101  2-hydroxyglutaryl-CoA dehydratase D-component  28.21 
 
 		 379 aa  148  2.0000000000000003e-34  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_008340  Mlg_0785  2-hydroxyglutaryl-CoA dehydratase, D-component  31.34 
 
 		 420 aa  144  3e-33  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.237879  normal  1 
 
 
-
 
NC_007575  Suden_0273  2-hydroxyglutaryl-CoA dehydratase, D-component  26.8 
 
 		 422 aa  140  3.9999999999999997e-32  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  1  n/a   
 
 
-
 
NC_011832  Mpal_1147  2-hydroxyglutaryl-CoA dehydratase D-component  25.72 
 
 		 393 aa  135  9e-31  Methanosphaerula palustris E1-9c  Archaea  normal  0.132933  normal  1 
 
 
-
 
NC_008609  Ppro_1278  2-hydroxyglutaryl-CoA dehydratase, D-component  26.33 
 
 		 413 aa  106  8e-22  Pelobacter propionicus DSM 2379  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_3877  2-hydroxyglutaryl-CoA dehydratase, D-component  23.12 
 
 		 395 aa  88.6  2e-16  Geobacter uraniireducens Rf4  Bacteria  normal  1  n/a   
 
 
-
 
NC_013385  Adeg_1708  2-hydroxyglutaryl-CoA dehydratase D-component  24.51 
 
 		 322 aa  88.6  2e-16  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1007  2-hydroxyglutaryl-CoA dehydratase, D-component  24.93 
 
 		 349 aa  87.4  4e-16  Moorella thermoacetica ATCC 39073  Bacteria  decreased coverage  0.0000000530359  hitchhiker  0.000167288 
 
 
-
 
NC_009943  Dole_2774  2-hydroxyglutaryl-CoA dehydratase D-component  23.92 
 
 		 376 aa  85.9  0.000000000000001  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_007925  RPC_2055  2-hydroxyglutaryl-CoA dehydratase, D-component  22.56 
 
 		 376 aa  85.5  0.000000000000002  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.574959  normal  0.736744 
 
 
-
 
NC_009943  Dole_2769  2-hydroxyglutaryl-CoA dehydratase D-component  23.88 
 
 		 379 aa  83.6  0.000000000000005  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1772  2-hydroxyglutaryl-CoA dehydratase D-component  21.78 
 
 		 358 aa  79.7  0.00000000000007  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.39587 
 
 
-
 
NC_009943  Dole_0891  2-hydroxyglutaryl-CoA dehydratase D-component  24.32 
 
 		 373 aa  77  0.0000000000006  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_3454  2-hydroxyglutaryl-CoA dehydratase D-component  23.18 
 
 		 386 aa  73.6  0.000000000006  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_011661  Dtur_1747  2-hydroxyglutaryl-CoA dehydratase D-component  21.76 
 
 		 339 aa  68.6  0.0000000002  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1771  2-hydroxyglutaryl-CoA dehydratase D-component  21.72 
 
 		 419 aa  63.9  0.000000004  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.433973 
 
 
-
 
NC_009943  Dole_1686  2-hydroxyglutaryl-CoA dehydratase D-component  22.13 
 
 		 370 aa  63.9  0.000000005  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0274681  n/a   
 
 
-
 
NC_011899  Hore_16090  2-hydroxyglutaryl-CoA dehydratase D-component  22.79 
 
 		 355 aa  60.8  0.00000004  Halothermothrix orenii H 168  Bacteria  normal  1  n/a   
 
 
-
 
NC_010320  Teth514_1898  putative CoA-substrate-specific enzyme activase  23.73 
 
 		 539 aa  57  0.0000005  Thermoanaerobacter sp. X514  Bacteria  normal  1  n/a   
 
 
-
 
NC_009943  Dole_2775  2-hydroxyglutaryl-CoA dehydratase D-component  20.43 
 
 		 469 aa  52  0.00002  Desulfococcus oleovorans Hxd3  Bacteria  normal  1  n/a   
 
 
-
 
NC_007958  RPD_1538  benzoyl-CoA reductase, subunit C  22.47 
 
 		 394 aa  51.2  0.00003  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.130058  normal  1 
 
 
-
 
NC_011004  Rpal_0725  benzoyl-CoA reductase, subunit B  22.62 
 
 		 436 aa  51.2  0.00003  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.0743165  n/a   
 
 
-
 
NC_007925  RPC_1029  benzoyl-CoA reductase, subunit C  22.47 
 
 		 394 aa  49.7  0.00008  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007958  RPD_1537  benzoyl-CoA reductase, subunit B  22.22 
 
 		 436 aa  49.7  0.00009  Rhodopseudomonas palustris BisB5  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011004  Rpal_0724  benzoyl-CoA reductase, subunit C  23.21 
 
 		 394 aa  47.4  0.0005  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.377082  n/a   
 
 
-
 
NC_007925  RPC_1028  benzoyl-CoA reductase, subunit B  21.83 
 
 		 436 aa  47  0.0005  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.659729  normal  1 
 
 
-
 
NC_009943  Dole_0930  2-hydroxyglutaryl-CoA dehydratase D-component  21.94 
 
 		 377 aa  46.2  0.001  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0187897  n/a   
 
 
-
 
NC_013552  DhcVS_532  hypothetical protein  23.72 
 
 		 336 aa  46.2  0.001  Dehalococcoides sp. VS  Bacteria  hitchhiker  0.00368182  n/a   
 
 
-
 
NC_009943  Dole_1685  2-hydroxyglutaryl-CoA dehydratase D-component  19.94 
 
 		 424 aa  45.1  0.002  Desulfococcus oleovorans Hxd3  Bacteria  hitchhiker  0.00000455282  n/a   
 
 
-
 
NC_011662  Tmz1t_2950  benzoyl-CoA reductase, subunit B  21.84 
 
 		 432 aa  43.9  0.004  Thauera sp. MZ1T  Bacteria  normal  1  n/a   
 
 
-
 
NC_013216  Dtox_3625  2-hydroxyglutaryl-CoA dehydratase D-component  24.79 
 
 		 325 aa  43.9  0.005  Desulfotomaculum acetoxidans DSM 771  Bacteria  unclonable  0.00000000225912  normal  0.25533 
 
 
-
 
NC_011830  Dhaf_3453  2-hydroxyglutaryl-CoA dehydratase D-component  20.5 
 
 		 409 aa  43.1  0.007  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
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