More than 300 homologs were found in PanDaTox collection
for query gene Mrub_1539 on replicon NC_013946
Organism: Meiothermus ruber DSM 1279



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013946  Mrub_1539  two component transcriptional regulator, winged helix family  100 
 
 
222 aa  433  1e-120  Meiothermus ruber DSM 1279  Bacteria  hitchhiker  0.0000287281  normal  0.103291 
 
 
-
 
NC_014212  Mesil_0841  two component transcriptional regulator, winged helix family  86.04 
 
 
223 aa  384  1e-106  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_008025  Dgeo_0130  two component transcriptional regulator  57.85 
 
 
229 aa  231  5e-60  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.848842  normal 
 
 
-
 
NC_013946  Mrub_0302  two component transcriptional regulator, winged helix family  52.04 
 
 
221 aa  212  2.9999999999999995e-54  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_014212  Mesil_0142  two component transcriptional regulator, winged helix family  52.7 
 
 
221 aa  212  4.9999999999999996e-54  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.709604 
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  46.32 
 
 
232 aa  204  8e-52  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  48.9 
 
 
231 aa  198  3.9999999999999996e-50  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_008010  Dgeo_2564  two component transcriptional regulator  48.65 
 
 
244 aa  196  2.0000000000000003e-49  Deinococcus geothermalis DSM 11300  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_0411  two component transcriptional regulator  45.37 
 
 
230 aa  192  4e-48  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_4021  two component transcriptional regulator, winged helix family  48.03 
 
 
235 aa  191  5e-48  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_008025  Dgeo_0087  two component transcriptional regulator  51.8 
 
 
222 aa  191  8e-48  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_011830  Dhaf_4050  two component transcriptional regulator, winged helix family  49.12 
 
 
227 aa  190  1e-47  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00552008  n/a   
 
 
-
 
NC_013510  Tcur_0700  two component transcriptional regulator, winged helix family  46.26 
 
 
226 aa  190  2e-47  Thermomonospora curvata DSM 43183  Bacteria  normal  0.768939  n/a   
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  45.41 
 
 
229 aa  189  2.9999999999999997e-47  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_014212  Mesil_2802  two component transcriptional regulator, winged helix family  50 
 
 
219 aa  189  2.9999999999999997e-47  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.204502 
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  44.49 
 
 
226 aa  188  5e-47  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_011831  Cagg_0393  two component transcriptional regulator, winged helix family  47.79 
 
 
227 aa  188  5e-47  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal  0.202895 
 
 
-
 
NC_013440  Hoch_0552  two component transcriptional regulator, winged helix family  47.53 
 
 
226 aa  187  9e-47  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.496663 
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  46.96 
 
 
232 aa  187  9e-47  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  44.93 
 
 
231 aa  187  1e-46  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_009675  Anae109_4159  two component transcriptional regulator  46.7 
 
 
230 aa  187  1e-46  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.667277  normal  0.0359145 
 
 
-
 
NC_012034  Athe_1487  two component transcriptional regulator, winged helix family  43.23 
 
 
232 aa  186  2e-46  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.487145  n/a   
 
 
-
 
NC_009767  Rcas_2782  two component transcriptional regulator  47.11 
 
 
231 aa  186  2e-46  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.92379  normal 
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  44.93 
 
 
229 aa  186  3e-46  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_0961  response regulator receiver protein  44.93 
 
 
229 aa  186  3e-46  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_011830  Dhaf_3739  two component transcriptional regulator, winged helix family  44.93 
 
 
230 aa  185  4e-46  Desulfitobacterium hafniense DCB-2  Bacteria  decreased coverage  0.0000000000466515  n/a   
 
 
-
 
NC_011899  Hore_21640  two component transcriptional regulator, winged helix family  42.29 
 
 
226 aa  185  5e-46  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000000176926  n/a   
 
 
-
 
NC_013131  Caci_8215  two component transcriptional regulator, winged helix family  44.93 
 
 
226 aa  185  5e-46  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  47.16 
 
 
235 aa  184  8e-46  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013501  Rmar_0987  two component transcriptional regulator, winged helix family  48.68 
 
 
233 aa  184  8e-46  Rhodothermus marinus DSM 4252  Bacteria  normal  0.195539  n/a   
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  43.61 
 
 
236 aa  184  1.0000000000000001e-45  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  47.98 
 
 
236 aa  184  1.0000000000000001e-45  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0875  two component transcriptional regulator  40.87 
 
 
242 aa  184  1.0000000000000001e-45  Petrotoga mobilis SJ95  Bacteria  decreased coverage  0.000486966  n/a   
 
 
-
 
NC_010424  Daud_1419  two component transcriptional regulator  48.25 
 
 
231 aa  184  1.0000000000000001e-45  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0720218  n/a   
 
 
-
 
NC_011891  A2cp1_0440  two component transcriptional regulator, winged helix family  45.18 
 
 
230 aa  183  1.0000000000000001e-45  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  44.05 
 
 
240 aa  184  1.0000000000000001e-45  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_011886  Achl_0850  two component transcriptional regulator, winged helix family  44.49 
 
 
226 aa  183  1.0000000000000001e-45  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  42.86 
 
 
232 aa  184  1.0000000000000001e-45  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_0724  two component transcriptional regulator  43.61 
 
 
226 aa  183  2.0000000000000003e-45  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  44.49 
 
 
236 aa  183  2.0000000000000003e-45  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  45.58 
 
 
237 aa  182  3e-45  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_008578  Acel_1832  two component transcriptional regulator  46.05 
 
 
245 aa  182  3e-45  Acidothermus cellulolyticus 11B  Bacteria  normal  0.366424  normal  0.561636 
 
 
-
 
NC_011145  AnaeK_0439  two component transcriptional regulator, winged helix family  44.74 
 
 
230 aa  182  4.0000000000000006e-45  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  42.06 
 
 
235 aa  182  4.0000000000000006e-45  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_6749  two component transcriptional regulator, winged helix family  44.93 
 
 
226 aa  182  4.0000000000000006e-45  Actinosynnema mirum DSM 43827  Bacteria  normal  0.290774  n/a   
 
 
-
 
NC_008699  Noca_4046  response regulator receiver  42.92 
 
 
225 aa  182  4.0000000000000006e-45  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_007404  Tbd_0216  two component transcriptional regulator  46.43 
 
 
230 aa  182  5.0000000000000004e-45  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal  0.305183 
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  43.86 
 
 
228 aa  181  5.0000000000000004e-45  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  40.26 
 
 
239 aa  181  7e-45  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  40.26 
 
 
239 aa  181  7e-45  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_008148  Rxyl_0378  two component transcriptional regulator  44.64 
 
 
234 aa  181  8.000000000000001e-45  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  44.35 
 
 
234 aa  181  1e-44  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  44.16 
 
 
239 aa  180  2e-44  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_009832  Spro_1041  two component transcriptional regulator  43.5 
 
 
229 aa  179  2.9999999999999997e-44  Serratia proteamaculans 568  Bacteria  normal  normal  0.194422 
 
 
-
 
NC_010465  YPK_3276  two component transcriptional regulator  43.5 
 
 
229 aa  179  2.9999999999999997e-44  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_3302  two component transcriptional regulator, winged helix family  45.61 
 
 
231 aa  179  2.9999999999999997e-44  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.000343135 
 
 
-
 
NC_010159  YpAngola_A3286  phosphate regulon transcriptional regulatory protein  43.5 
 
 
230 aa  179  2.9999999999999997e-44  Yersinia pestis Angola  Bacteria  normal  normal  0.0413143 
 
 
-
 
NC_009708  YpsIP31758_3136  phosphate regulon transcriptional regulatory protein PhoB  43.5 
 
 
229 aa  179  2.9999999999999997e-44  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  43.42 
 
 
236 aa  179  4e-44  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_011149  SeAg_B0435  transcriptional regulator PhoB  44.84 
 
 
229 aa  179  4e-44  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_1997  two component transcriptional regulator  43.36 
 
 
234 aa  179  4e-44  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.000000742772  n/a   
 
 
-
 
NC_008709  Ping_2232  two component transcriptional regulator, winged helix family protein  42.86 
 
 
227 aa  179  4e-44  Psychromonas ingrahamii 37  Bacteria  normal  0.326614  normal  0.43086 
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  43.17 
 
 
234 aa  178  4.999999999999999e-44  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  43.17 
 
 
234 aa  178  4.999999999999999e-44  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_007333  Tfu_2910  response regulator receiver  44.05 
 
 
230 aa  177  8e-44  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_003910  CPS_1208  phosphate regulon response regulator PhoB  41.7 
 
 
233 aa  177  9e-44  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_4602  two component transcriptional regulator, winged helix family  42.29 
 
 
226 aa  177  9e-44  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_012912  Dd1591_3106  two component transcriptional regulator PhoB, winged helix family  43.5 
 
 
229 aa  177  9e-44  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP1256  alkaline phosphatase synthesis transcriptional regulatory protein PhoP  42.42 
 
 
236 aa  177  1e-43  Staphylococcus epidermidis RP62A  Bacteria  normal  0.577358  n/a   
 
 
-
 
NC_004116  SAG1961  phosphate regulon response regulator PhoB  43.3 
 
 
225 aa  177  1e-43  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.411469  n/a   
 
 
-
 
NC_012917  PC1_1008  two component transcriptional regulator PhoB, winged helix family  43.5 
 
 
229 aa  177  1e-43  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_011205  SeD_A0435  transcriptional regulator PhoB  44.39 
 
 
229 aa  177  1e-43  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  0.464381  normal 
 
 
-
 
NC_011094  SeSA_A0454  transcriptional regulator PhoB  44.39 
 
 
229 aa  177  1e-43  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  normal 
 
 
-
 
NC_013174  Jden_2083  two component transcriptional regulator, winged helix family  41.53 
 
 
237 aa  177  1e-43  Jonesia denitrificans DSM 20603  Bacteria  normal  0.873655  normal 
 
 
-
 
NC_013947  Snas_0580  two component transcriptional regulator, winged helix family  42.98 
 
 
226 aa  177  1e-43  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_014151  Cfla_0657  two component transcriptional regulator, winged helix family  44.87 
 
 
235 aa  177  1e-43  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.118815  hitchhiker  0.000311431 
 
 
-
 
NC_008254  Meso_3116  two component transcriptional regulator  44.05 
 
 
229 aa  177  1e-43  Chelativorans sp. BNC1  Bacteria  normal  0.202822  n/a   
 
 
-
 
NC_008531  LEUM_1950  DNA-binding response regulator  41.88 
 
 
235 aa  177  1e-43  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.100456  n/a   
 
 
-
 
NC_011083  SeHA_C0496  transcriptional regulator PhoB  44.39 
 
 
229 aa  177  1e-43  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  normal 
 
 
-
 
NC_009012  Cthe_1847  two component transcriptional regulator  40.35 
 
 
234 aa  177  1e-43  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.00000121968  n/a   
 
 
-
 
NC_013421  Pecwa_3302  two component transcriptional regulator PhoB, winged helix family  43.5 
 
 
229 aa  177  1e-43  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_002977  MCA3105  DNA-binding response regulator PhoB  42.86 
 
 
232 aa  176  2e-43  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0080  two component transcriptional regulator, winged helix family  41.3 
 
 
230 aa  177  2e-43  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_2051  response regulator receiver:transcriptional regulatory protein, C-terminal  43.11 
 
 
230 aa  177  2e-43  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.191031  normal  0.53595 
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  42.79 
 
 
256 aa  176  2e-43  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_24530  Response regulator KdpE  44.74 
 
 
232 aa  176  2e-43  Azotobacter vinelandii DJ  Bacteria  normal  0.0689152  n/a   
 
 
-
 
NC_011080  SNSL254_A0441  transcriptional regulator PhoB  44.39 
 
 
229 aa  176  2e-43  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  0.244741  normal 
 
 
-
 
NC_009436  Ent638_0867  transcriptional regulator PhoB  43.5 
 
 
229 aa  176  2e-43  Enterobacter sp. 638  Bacteria  normal  0.437737  normal 
 
 
-
 
NC_008825  Mpe_A1277  two component transcriptional regulator  45.37 
 
 
233 aa  176  2e-43  Methylibium petroleiphilum PM1  Bacteria  normal  0.0649233  normal  0.253886 
 
 
-
 
NC_011661  Dtur_1237  two component transcriptional regulator, winged helix family  40.35 
 
 
232 aa  177  2e-43  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_011901  Tgr7_2472  response regulator receiver protein  46.53 
 
 
216 aa  176  3e-43  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_3394  two component transcriptional regulator, winged helix family  42.36 
 
 
230 aa  176  3e-43  Clostridium cellulolyticum H10  Bacteria  normal  0.103692  n/a   
 
 
-
 
NC_013174  Jden_1871  two component transcriptional regulator, winged helix family  44.2 
 
 
226 aa  176  3e-43  Jonesia denitrificans DSM 20603  Bacteria  normal  0.105791  normal  0.266081 
 
 
-
 
NC_009523  RoseRS_3818  two component transcriptional regulator  44.49 
 
 
230 aa  176  3e-43  Roseiflexus sp. RS-1  Bacteria  normal  0.386967  normal  0.165932 
 
 
-
 
NC_002947  PP_4157  winged helix family two component transcriptional regulator  44.44 
 
 
231 aa  175  4e-43  Pseudomonas putida KT2440  Bacteria  normal  0.507569  normal 
 
 
-
 
NC_007520  Tcr_0541  two component transcriptional regulator  42.22 
 
 
230 aa  175  4e-43  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_009524  PsycPRwf_2093  two component transcriptional regulator  43.42 
 
 
233 aa  175  4e-43  Psychrobacter sp. PRwf-1  Bacteria  normal  0.582679  normal 
 
 
-
 
NC_010658  SbBS512_E0318  transcriptional regulator PhoB  43.95 
 
 
229 aa  175  5e-43  Shigella boydii CDC 3083-94  Bacteria  normal  n/a   
 
 
-
 
NC_011353  ECH74115_0475  transcriptional regulator PhoB  43.95 
 
 
229 aa  175  5e-43  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  normal 
 
 
-
 
NC_010498  EcSMS35_0429  transcriptional regulator PhoB  43.95 
 
 
229 aa  175  5e-43  Escherichia coli SMS-3-5  Bacteria  normal  0.283039  normal 
 
 
-
 
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