More than 300 homologs were found in PanDaTox collection
for query gene Mrub_0302 on replicon NC_013946
Organism: Meiothermus ruber DSM 1279



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013946  Mrub_0302  two component transcriptional regulator, winged helix family  100 
 
 
221 aa  433  1e-121  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_014212  Mesil_0142  two component transcriptional regulator, winged helix family  80.54 
 
 
221 aa  358  5e-98  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.709604 
 
 
-
 
NC_008010  Dgeo_2564  two component transcriptional regulator  65.28 
 
 
244 aa  278  6e-74  Deinococcus geothermalis DSM 11300  Bacteria  normal  n/a   
 
 
-
 
NC_008025  Dgeo_0087  two component transcriptional regulator  66.06 
 
 
222 aa  261  6e-69  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_014212  Mesil_2802  two component transcriptional regulator, winged helix family  50.45 
 
 
219 aa  217  1e-55  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.204502 
 
 
-
 
NC_014212  Mesil_0841  two component transcriptional regulator, winged helix family  53.39 
 
 
223 aa  215  4e-55  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  48.23 
 
 
234 aa  212  3.9999999999999995e-54  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  53.36 
 
 
237 aa  210  2e-53  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_008262  CPR_0609  DNA-binding response regulator  47.09 
 
 
231 aa  206  2e-52  Clostridium perfringens SM101  Bacteria  hitchhiker  0.0000282114  n/a   
 
 
-
 
NC_008261  CPF_0623  DNA-binding response regulator  47.53 
 
 
231 aa  205  5e-52  Clostridium perfringens ATCC 13124  Bacteria  hitchhiker  0.000212568  n/a   
 
 
-
 
NC_009767  Rcas_2782  two component transcriptional regulator  49.34 
 
 
231 aa  202  3e-51  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.92379  normal 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  47.79 
 
 
229 aa  201  7e-51  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  47.51 
 
 
223 aa  200  9.999999999999999e-51  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_1696  two component transcriptional regulator, winged helix family  45.54 
 
 
224 aa  200  9.999999999999999e-51  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  49.32 
 
 
223 aa  200  9.999999999999999e-51  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  47.06 
 
 
223 aa  199  1.9999999999999998e-50  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  47.06 
 
 
223 aa  199  1.9999999999999998e-50  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_0827  two component transcriptional regulator  51.79 
 
 
256 aa  199  1.9999999999999998e-50  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00211389  normal  0.244563 
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  46.72 
 
 
239 aa  200  1.9999999999999998e-50  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  47.06 
 
 
223 aa  199  3e-50  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  47.06 
 
 
223 aa  199  3e-50  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011831  Cagg_3302  two component transcriptional regulator, winged helix family  49.12 
 
 
231 aa  199  3e-50  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.000343135 
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  48.88 
 
 
236 aa  199  3e-50  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_005957  BT9727_1191  response regulator  47.06 
 
 
223 aa  198  3.9999999999999996e-50  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  47.53 
 
 
228 aa  198  3.9999999999999996e-50  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  47.51 
 
 
223 aa  198  5e-50  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  47.06 
 
 
223 aa  198  5e-50  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  47.06 
 
 
223 aa  198  5e-50  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  46.29 
 
 
239 aa  198  7e-50  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  46.29 
 
 
239 aa  198  7e-50  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  48.43 
 
 
240 aa  197  9e-50  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  46.61 
 
 
223 aa  196  2.0000000000000003e-49  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_010184  BcerKBAB4_3138  two component transcriptional regulator  47.53 
 
 
224 aa  196  2.0000000000000003e-49  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_0353  two component transcriptional regulator  48.47 
 
 
230 aa  195  4.0000000000000005e-49  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.683455 
 
 
-
 
NC_003909  BCE_4720  DNA-binding response regulator PhoP  44.98 
 
 
239 aa  195  4.0000000000000005e-49  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS4484  DNA-binding response regulator PhoP  44.98 
 
 
239 aa  195  4.0000000000000005e-49  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4319  alkaline phosphatase synthesis response regulator  44.98 
 
 
239 aa  195  4.0000000000000005e-49  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  44.98 
 
 
239 aa  195  4.0000000000000005e-49  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4704  DNA-binding response regulator PhoP  44.98 
 
 
239 aa  195  4.0000000000000005e-49  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000000673192 
 
 
-
 
NC_011658  BCAH187_A4714  DNA-binding response regulator PhoP  44.98 
 
 
239 aa  195  4.0000000000000005e-49  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4833  DNA-binding response regulator PhoP  44.98 
 
 
239 aa  195  4.0000000000000005e-49  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0982965  n/a   
 
 
-
 
NC_010320  Teth514_1155  two component transcriptional regulator  43.75 
 
 
231 aa  195  5.000000000000001e-49  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000430064  n/a   
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  44.98 
 
 
239 aa  195  5.000000000000001e-49  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  44.98 
 
 
239 aa  195  5.000000000000001e-49  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_012034  Athe_1487  two component transcriptional regulator, winged helix family  46.26 
 
 
232 aa  194  7e-49  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.487145  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  44.98 
 
 
239 aa  194  8.000000000000001e-49  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_2041  DNA-binding response regulator  44.8 
 
 
225 aa  194  9e-49  Bacillus cereus ATCC 10987  Bacteria  normal  0.0972255  n/a   
 
 
-
 
NC_013235  Namu_2566  two component transcriptional regulator, winged helix family  50.44 
 
 
229 aa  194  9e-49  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.000356007  hitchhiker  0.00345607 
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  47.53 
 
 
236 aa  194  9e-49  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_009674  Bcer98_3274  two component transcriptional regulator  44.74 
 
 
238 aa  194  1e-48  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  47.81 
 
 
232 aa  194  1e-48  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  47.11 
 
 
235 aa  194  1e-48  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011658  BCAH187_A2062  DNA-binding response regulator  44.8 
 
 
225 aa  194  1e-48  Bacillus cereus AH187  Bacteria  hitchhiker  0.0000169038  n/a   
 
 
-
 
NC_010320  Teth514_0766  two component transcriptional regulator  43.3 
 
 
231 aa  194  1e-48  Thermoanaerobacter sp. X514  Bacteria  normal  0.585906  n/a   
 
 
-
 
NC_011831  Cagg_0243  two component transcriptional regulator, winged helix family  48.03 
 
 
235 aa  194  1e-48  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.0646165  normal 
 
 
-
 
NC_013946  Mrub_1539  two component transcriptional regulator, winged helix family  52.04 
 
 
222 aa  194  1e-48  Meiothermus ruber DSM 1279  Bacteria  hitchhiker  0.0000287281  normal  0.103291 
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  47.6 
 
 
236 aa  193  2e-48  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_007413  Ava_3369  two component transcriptional regulator  47.19 
 
 
250 aa  192  2e-48  Anabaena variabilis ATCC 29413  Bacteria  normal  0.881494  normal  0.845013 
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  48.67 
 
 
231 aa  193  2e-48  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_1419  two component transcriptional regulator  48.9 
 
 
231 aa  192  4e-48  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0720218  n/a   
 
 
-
 
NC_006274  BCZK1772  response regulator  44.8 
 
 
254 aa  192  5e-48  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_5905  two component transcriptional regulator, winged helix family  46.26 
 
 
237 aa  191  5e-48  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_011725  BCB4264_A1962  DNA-binding response regulator  43.89 
 
 
225 aa  191  5e-48  Bacillus cereus B4264  Bacteria  normal  0.597164  n/a   
 
 
-
 
NC_011773  BCAH820_1991  DNA-binding response regulator  44.8 
 
 
254 aa  191  6e-48  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  4.9362699999999994e-45 
 
 
-
 
NC_005957  BT9727_1790  response regulator  44.34 
 
 
254 aa  191  8e-48  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.0306127  n/a   
 
 
-
 
NC_007530  GBAA_1955  DNA-binding response regulator  44.8 
 
 
228 aa  191  8e-48  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_3085  two component transcriptional regulator, winged helix family  48.89 
 
 
232 aa  191  8e-48  Desulfotomaculum acetoxidans DSM 771  Bacteria  unclonable  0.00000000315463  hitchhiker  0.000599707 
 
 
-
 
NC_014248  Aazo_2741  winged helix family two component transcriptional regulator  45.45 
 
 
250 aa  191  8e-48  'Nostoc azollae' 0708  Bacteria  normal  0.0957275  n/a   
 
 
-
 
NC_005945  BAS1816  DNA-binding response regulator  44.8 
 
 
254 aa  191  9e-48  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_014158  Tpau_0093  two component transcriptional regulator, winged helix family  47.3 
 
 
232 aa  191  1e-47  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_011726  PCC8801_3460  two component transcriptional regulator, winged helix family  43.91 
 
 
250 aa  190  1e-47  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_2657  two component transcriptional regulator, winged helix family  43.91 
 
 
250 aa  191  1e-47  Cyanothece sp. PCC 8802  Bacteria  normal  normal  0.350713 
 
 
-
 
NC_011772  BCG9842_B3366  DNA-binding response regulator  43.44 
 
 
225 aa  190  2e-47  Bacillus cereus G9842  Bacteria  normal  0.166078  hitchhiker  0.00000000000000126215 
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  45.74 
 
 
237 aa  189  2.9999999999999997e-47  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_009523  RoseRS_0805  two component transcriptional regulator  48.66 
 
 
229 aa  189  2.9999999999999997e-47  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_008346  Swol_1681  response regulator receiver protein  43.95 
 
 
227 aa  189  2.9999999999999997e-47  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.0956507  n/a   
 
 
-
 
NC_012793  GWCH70_3409  two component transcriptional regulator, winged helix family  45.41 
 
 
236 aa  189  2.9999999999999997e-47  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_0378  two component transcriptional regulator  45.02 
 
 
234 aa  189  4e-47  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  43.95 
 
 
228 aa  189  4e-47  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_009767  Rcas_0997  two component transcriptional regulator  48.89 
 
 
230 aa  188  5e-47  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.679101  normal 
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  48.23 
 
 
236 aa  188  5e-47  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  45.73 
 
 
233 aa  188  7e-47  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_1176  two component transcriptional regulator  48.02 
 
 
229 aa  187  8e-47  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.149936 
 
 
-
 
NC_012793  GWCH70_1924  two component transcriptional regulator, winged helix family  43.89 
 
 
225 aa  187  1e-46  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  42.61 
 
 
232 aa  186  2e-46  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_1085  two component transcriptional regulator, winged helix family  47.41 
 
 
235 aa  186  2e-46  Cyanothece sp. PCC 7425  Bacteria  normal  0.224574  normal 
 
 
-
 
NC_007760  Adeh_0411  two component transcriptional regulator  45.33 
 
 
230 aa  186  2e-46  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1181  two component transcriptional regulator, winged helix family  48.87 
 
 
234 aa  186  2e-46  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.00335068 
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  43.17 
 
 
229 aa  186  2e-46  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  47.06 
 
 
236 aa  186  2e-46  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_1847  two component transcriptional regulator  41.85 
 
 
234 aa  186  2e-46  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.00000121968  n/a   
 
 
-
 
NC_011830  Dhaf_4050  two component transcriptional regulator, winged helix family  45.81 
 
 
227 aa  186  3e-46  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00552008  n/a   
 
 
-
 
NC_009523  RoseRS_3818  two component transcriptional regulator  48.89 
 
 
230 aa  186  3e-46  Roseiflexus sp. RS-1  Bacteria  normal  0.386967  normal  0.165932 
 
 
-
 
NC_008531  LEUM_0585  DNA-binding response regulator  43.36 
 
 
230 aa  186  3e-46  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  hitchhiker  0.00125793  n/a   
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  45.33 
 
 
234 aa  185  4e-46  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_008010  Dgeo_2598  two component transcriptional regulator  68.94 
 
 
134 aa  185  4e-46  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.157515  n/a   
 
 
-
 
NC_008527  LACR_0444  DNA-binding response regulator  45.37 
 
 
233 aa  185  4e-46  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  45.33 
 
 
234 aa  185  4e-46  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  41.44 
 
 
223 aa  185  5e-46  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_010003  Pmob_0875  two component transcriptional regulator  43.67 
 
 
242 aa  185  5e-46  Petrotoga mobilis SJ95  Bacteria  decreased coverage  0.000486966  n/a   
 
 
-
 
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