More than 300 homologs were found in PanDaTox collection
for query gene Mesil_0142 on replicon NC_014212
Organism: Meiothermus silvanus DSM 9946



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014212  Mesil_0142  two component transcriptional regulator, winged helix family  100 
 
 
221 aa  427  1e-119  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.709604 
 
 
-
 
NC_013946  Mrub_0302  two component transcriptional regulator, winged helix family  80.54 
 
 
221 aa  358  5e-98  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_008010  Dgeo_2564  two component transcriptional regulator  62.39 
 
 
244 aa  268  5.9999999999999995e-71  Deinococcus geothermalis DSM 11300  Bacteria  normal  n/a   
 
 
-
 
NC_008025  Dgeo_0087  two component transcriptional regulator  65.61 
 
 
222 aa  262  4e-69  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_014212  Mesil_2802  two component transcriptional regulator, winged helix family  52.73 
 
 
219 aa  217  8.999999999999998e-56  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.204502 
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  53.57 
 
 
237 aa  212  2.9999999999999995e-54  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  48.89 
 
 
234 aa  211  4.9999999999999996e-54  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_014212  Mesil_0841  two component transcriptional regulator, winged helix family  53.15 
 
 
223 aa  210  2e-53  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_2782  two component transcriptional regulator  51.12 
 
 
231 aa  207  1e-52  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.92379  normal 
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  49.33 
 
 
240 aa  205  4e-52  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  50.65 
 
 
239 aa  205  4e-52  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  48.46 
 
 
235 aa  205  6e-52  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  49.78 
 
 
236 aa  204  6e-52  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_003909  BCE_4720  DNA-binding response regulator PhoP  46.75 
 
 
239 aa  203  2e-51  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS4484  DNA-binding response regulator PhoP  46.75 
 
 
239 aa  203  2e-51  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4319  alkaline phosphatase synthesis response regulator  46.75 
 
 
239 aa  203  2e-51  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  46.75 
 
 
239 aa  203  2e-51  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  46.75 
 
 
239 aa  203  2e-51  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4833  DNA-binding response regulator PhoP  46.75 
 
 
239 aa  203  2e-51  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0982965  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  46.75 
 
 
239 aa  203  2e-51  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_011773  BCAH820_4704  DNA-binding response regulator PhoP  46.75 
 
 
239 aa  203  2e-51  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000000673192 
 
 
-
 
NC_011658  BCAH187_A4714  DNA-binding response regulator PhoP  46.75 
 
 
239 aa  203  2e-51  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  46.75 
 
 
239 aa  202  2e-51  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  47.3 
 
 
223 aa  202  3e-51  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  47.3 
 
 
223 aa  202  3e-51  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  48.89 
 
 
236 aa  202  3e-51  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_008262  CPR_0609  DNA-binding response regulator  47.53 
 
 
231 aa  201  5e-51  Clostridium perfringens SM101  Bacteria  hitchhiker  0.0000282114  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  47.3 
 
 
223 aa  201  6e-51  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  47.3 
 
 
223 aa  201  6e-51  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  47.75 
 
 
223 aa  201  7e-51  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_013235  Namu_2566  two component transcriptional regulator, winged helix family  53.33 
 
 
229 aa  201  7e-51  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.000356007  hitchhiker  0.00345607 
 
 
-
 
NC_005957  BT9727_1191  response regulator  47.3 
 
 
223 aa  201  8e-51  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  47.3 
 
 
223 aa  201  9e-51  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  47.3 
 
 
223 aa  201  9e-51  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_1696  two component transcriptional regulator, winged helix family  45.29 
 
 
224 aa  200  1.9999999999999998e-50  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  48.66 
 
 
228 aa  199  1.9999999999999998e-50  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_011831  Cagg_3302  two component transcriptional regulator, winged helix family  48.89 
 
 
231 aa  199  1.9999999999999998e-50  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.000343135 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  48.02 
 
 
229 aa  199  3e-50  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_008261  CPF_0623  DNA-binding response regulator  47.53 
 
 
231 aa  199  3e-50  Clostridium perfringens ATCC 13124  Bacteria  hitchhiker  0.000212568  n/a   
 
 
-
 
NC_009674  Bcer98_3274  two component transcriptional regulator  46.96 
 
 
238 aa  199  3e-50  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  49.78 
 
 
232 aa  198  3.9999999999999996e-50  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  47.3 
 
 
223 aa  199  3.9999999999999996e-50  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  48.21 
 
 
237 aa  198  5e-50  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_009767  Rcas_0353  two component transcriptional regulator  51.1 
 
 
230 aa  197  1.0000000000000001e-49  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.683455 
 
 
-
 
NC_014248  Aazo_2741  winged helix family two component transcriptional regulator  48.48 
 
 
250 aa  197  1.0000000000000001e-49  'Nostoc azollae' 0708  Bacteria  normal  0.0957275  n/a   
 
 
-
 
NC_007413  Ava_3369  two component transcriptional regulator  47.84 
 
 
250 aa  196  2.0000000000000003e-49  Anabaena variabilis ATCC 29413  Bacteria  normal  0.881494  normal  0.845013 
 
 
-
 
NC_010424  Daud_1897  two component transcriptional regulator  49.55 
 
 
227 aa  196  2.0000000000000003e-49  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.151466  n/a   
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  47.3 
 
 
223 aa  197  2.0000000000000003e-49  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_0916  two component transcriptional regulator, winged helix family  45.74 
 
 
234 aa  196  3e-49  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  0.0276045  hitchhiker  9.727110000000001e-18 
 
 
-
 
NC_009012  Cthe_1847  two component transcriptional regulator  46.26 
 
 
234 aa  196  3e-49  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.00000121968  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  46.4 
 
 
223 aa  195  4.0000000000000005e-49  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_013739  Cwoe_5905  two component transcriptional regulator, winged helix family  49.12 
 
 
237 aa  195  4.0000000000000005e-49  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_013946  Mrub_1539  two component transcriptional regulator, winged helix family  52.7 
 
 
222 aa  195  6e-49  Meiothermus ruber DSM 1279  Bacteria  hitchhiker  0.0000287281  normal  0.103291 
 
 
-
 
NC_011831  Cagg_0243  two component transcriptional regulator, winged helix family  49.34 
 
 
235 aa  194  9e-49  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.0646165  normal 
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  47.35 
 
 
234 aa  193  2e-48  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  50.88 
 
 
231 aa  193  2e-48  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  47.35 
 
 
234 aa  193  2e-48  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1487  two component transcriptional regulator, winged helix family  47.6 
 
 
232 aa  192  3e-48  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.487145  n/a   
 
 
-
 
NC_009767  Rcas_0997  two component transcriptional regulator  49.56 
 
 
230 aa  191  7e-48  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.679101  normal 
 
 
-
 
NC_008010  Dgeo_2598  two component transcriptional regulator  72.73 
 
 
134 aa  191  8e-48  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.157515  n/a   
 
 
-
 
NC_013161  Cyan8802_2657  two component transcriptional regulator, winged helix family  44.35 
 
 
250 aa  191  9e-48  Cyanothece sp. PCC 8802  Bacteria  normal  normal  0.350713 
 
 
-
 
NC_011658  BCAH187_A2062  DNA-binding response regulator  43.05 
 
 
225 aa  190  1e-47  Bacillus cereus AH187  Bacteria  hitchhiker  0.0000169038  n/a   
 
 
-
 
NC_005957  BT9727_1790  response regulator  43.44 
 
 
254 aa  190  1e-47  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.0306127  n/a   
 
 
-
 
NC_011830  Dhaf_1367  two component transcriptional regulator, winged helix family  49.56 
 
 
230 aa  191  1e-47  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000177207  n/a   
 
 
-
 
NC_007760  Adeh_0411  two component transcriptional regulator  46.02 
 
 
230 aa  190  1e-47  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011726  PCC8801_3460  two component transcriptional regulator, winged helix family  44.35 
 
 
250 aa  190  1e-47  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_011899  Hore_13280  two component transcriptional regulator, winged helix family  44.44 
 
 
227 aa  191  1e-47  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000536961  n/a   
 
 
-
 
NC_002976  SERP1256  alkaline phosphatase synthesis transcriptional regulatory protein PhoP  47.16 
 
 
236 aa  189  2e-47  Staphylococcus epidermidis RP62A  Bacteria  normal  0.577358  n/a   
 
 
-
 
NC_010320  Teth514_1155  two component transcriptional regulator  44.2 
 
 
231 aa  189  2e-47  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000430064  n/a   
 
 
-
 
NC_010003  Pmob_0875  two component transcriptional regulator  43.04 
 
 
242 aa  189  2e-47  Petrotoga mobilis SJ95  Bacteria  decreased coverage  0.000486966  n/a   
 
 
-
 
NC_007644  Moth_0827  two component transcriptional regulator  50.67 
 
 
256 aa  189  2e-47  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00211389  normal  0.244563 
 
 
-
 
NC_013205  Aaci_1104  two component transcriptional regulator, winged helix family  47.98 
 
 
233 aa  190  2e-47  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_3085  two component transcriptional regulator, winged helix family  47.79 
 
 
232 aa  189  2.9999999999999997e-47  Desulfotomaculum acetoxidans DSM 771  Bacteria  unclonable  0.00000000315463  hitchhiker  0.000599707 
 
 
-
 
NC_003909  BCE_2041  DNA-binding response regulator  43.05 
 
 
225 aa  189  2.9999999999999997e-47  Bacillus cereus ATCC 10987  Bacteria  normal  0.0972255  n/a   
 
 
-
 
NC_011773  BCAH820_1991  DNA-binding response regulator  43.44 
 
 
254 aa  189  2.9999999999999997e-47  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  4.9362699999999994e-45 
 
 
-
 
NC_005945  BAS1816  DNA-binding response regulator  43.44 
 
 
254 aa  189  2.9999999999999997e-47  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  45.85 
 
 
236 aa  189  2.9999999999999997e-47  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_009675  Anae109_4159  two component transcriptional regulator  45.13 
 
 
230 aa  189  2.9999999999999997e-47  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.667277  normal  0.0359145 
 
 
-
 
NC_006274  BCZK1772  response regulator  43.44 
 
 
254 aa  189  2.9999999999999997e-47  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_1419  two component transcriptional regulator  49.12 
 
 
231 aa  189  2.9999999999999997e-47  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.0720218  n/a   
 
 
-
 
NC_014158  Tpau_0093  two component transcriptional regulator, winged helix family  45.54 
 
 
232 aa  189  2.9999999999999997e-47  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_1955  DNA-binding response regulator  43.05 
 
 
228 aa  189  2.9999999999999997e-47  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_2939  response regulator receiver  51.32 
 
 
232 aa  189  2.9999999999999997e-47  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_3138  two component transcriptional regulator  44.84 
 
 
224 aa  189  2.9999999999999997e-47  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  48.02 
 
 
236 aa  189  4e-47  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_010320  Teth514_0766  two component transcriptional regulator  43.75 
 
 
231 aa  188  5e-47  Thermoanaerobacter sp. X514  Bacteria  normal  0.585906  n/a   
 
 
-
 
NC_008346  Swol_1681  response regulator receiver protein  46.19 
 
 
227 aa  188  5.999999999999999e-47  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.0956507  n/a   
 
 
-
 
NC_007516  Syncc9605_1618  two component transcriptional regulator  45.61 
 
 
254 aa  187  9e-47  Synechococcus sp. CC9605  Bacteria  normal  normal  0.218753 
 
 
-
 
NC_008531  LEUM_0585  DNA-binding response regulator  43.36 
 
 
230 aa  187  9e-47  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  hitchhiker  0.00125793  n/a   
 
 
-
 
NC_009253  Dred_1903  two component transcriptional regulator  45.85 
 
 
230 aa  187  1e-46  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_0984  two component transcriptional regulator, winged helix family  44.26 
 
 
246 aa  187  1e-46  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.0723779 
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  44.93 
 
 
256 aa  187  1e-46  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_1012  two component transcriptional regulator  46.78 
 
 
257 aa  187  1e-46  Synechococcus elongatus PCC 7942  Bacteria  normal  0.658807  normal 
 
 
-
 
NC_008148  Rxyl_0378  two component transcriptional regulator  46.35 
 
 
234 aa  187  1e-46  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1714  two component transcriptional regulator, winged helix family  43.23 
 
 
234 aa  187  1e-46  Clostridium cellulolyticum H10  Bacteria  normal  0.233786  n/a   
 
 
-
 
NC_008709  Ping_2232  two component transcriptional regulator, winged helix family protein  45.78 
 
 
227 aa  187  1e-46  Psychromonas ingrahamii 37  Bacteria  normal  0.326614  normal  0.43086 
 
 
-
 
NC_011725  BCB4264_A1962  DNA-binding response regulator  42.15 
 
 
225 aa  186  2e-46  Bacillus cereus B4264  Bacteria  normal  0.597164  n/a   
 
 
-
 
NC_013205  Aaci_1728  two component transcriptional regulator, winged helix family  47.37 
 
 
233 aa  187  2e-46  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_008607  Ppro_3691  two component transcriptional regulator  45.98 
 
 
230 aa  186  2e-46  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_3818  two component transcriptional regulator  48.67 
 
 
230 aa  186  2e-46  Roseiflexus sp. RS-1  Bacteria  normal  0.386967  normal  0.165932 
 
 
-
 
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