More than 300 homologs were found in PanDaTox collection
for query gene Slin_2552 on replicon NC_013730
Organism: Spirosoma linguale DSM 74



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013730  Slin_2552  two component transcriptional regulator, winged helix family  100 
 
 
230 aa  464  9.999999999999999e-131  Spirosoma linguale DSM 74  Bacteria  hitchhiker  0.0000276879  normal  0.180215 
 
 
-
 
NC_013730  Slin_1849  two component transcriptional regulator, winged helix family  63.91 
 
 
228 aa  309  2e-83  Spirosoma linguale DSM 74  Bacteria  normal  0.418833  normal 
 
 
-
 
NC_013037  Dfer_2743  two component transcriptional regulator, winged helix family  62.17 
 
 
228 aa  308  4e-83  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_013037  Dfer_0577  two component transcriptional regulator, winged helix family  55.9 
 
 
231 aa  259  2e-68  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.0903513 
 
 
-
 
NC_013730  Slin_2929  two component transcriptional regulator, winged helix family  50.44 
 
 
230 aa  241  1e-62  Spirosoma linguale DSM 74  Bacteria  normal  0.0551332  normal 
 
 
-
 
NC_013730  Slin_2619  two component transcriptional regulator, winged helix family  49.12 
 
 
224 aa  237  1e-61  Spirosoma linguale DSM 74  Bacteria  normal  0.189992  normal 
 
 
-
 
NC_013132  Cpin_3739  two component transcriptional regulator, winged helix family  47.83 
 
 
266 aa  236  3e-61  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.453489  normal  0.0202921 
 
 
-
 
NC_013037  Dfer_2762  two component transcriptional regulator, winged helix family  49.12 
 
 
225 aa  234  1.0000000000000001e-60  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_4793  two component transcriptional regulator, winged helix family  48.68 
 
 
225 aa  226  2e-58  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  47.37 
 
 
223 aa  226  3e-58  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_013037  Dfer_0453  two component transcriptional regulator, winged helix family  52.63 
 
 
225 aa  223  2e-57  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.904663  normal 
 
 
-
 
NC_013730  Slin_2944  two component transcriptional regulator, winged helix family  45.18 
 
 
223 aa  216  2e-55  Spirosoma linguale DSM 74  Bacteria  normal  0.470859  normal  0.70587 
 
 
-
 
NC_013730  Slin_0732  two component transcriptional regulator, winged helix family  48.02 
 
 
231 aa  215  5e-55  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_1345  response regulator receiver  46.55 
 
 
227 aa  213  1.9999999999999998e-54  Pedobacter heparinus DSM 2366  Bacteria  normal  normal  0.71904 
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  50.22 
 
 
226 aa  213  1.9999999999999998e-54  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  47.37 
 
 
224 aa  213  2.9999999999999995e-54  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  47.14 
 
 
240 aa  212  4.9999999999999996e-54  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_013037  Dfer_0274  two component transcriptional regulator, winged helix family  47.37 
 
 
232 aa  211  7e-54  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.701823  normal  0.83989 
 
 
-
 
CP001637  EcDH1_3058  two component heavy metal response transcriptional regulator, winged helix family  46.02 
 
 
227 aa  210  2e-53  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  46.05 
 
 
224 aa  210  2e-53  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_011353  ECH74115_0651  DNA-binding transcriptional activator CusR  46.02 
 
 
227 aa  210  2e-53  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  0.589216  normal 
 
 
-
 
NC_009800  EcHS_A0618  DNA-binding transcriptional activator CusR  46.02 
 
 
227 aa  210  2e-53  Escherichia coli HS  Bacteria  hitchhiker  0.000374882  n/a   
 
 
-
 
NC_010498  EcSMS35_0588  DNA-binding transcriptional activator CusR  46.02 
 
 
227 aa  210  2e-53  Escherichia coli SMS-3-5  Bacteria  normal  0.372008  normal 
 
 
-
 
NC_010468  EcolC_3075  DNA-binding transcriptional activator CusR  46.02 
 
 
227 aa  210  2e-53  Escherichia coli ATCC 8739  Bacteria  normal  0.204173  normal 
 
 
-
 
CP001509  ECD_00532  DNA-binding response regulator in two-component regulatory system with CusS  45.58 
 
 
227 aa  209  3e-53  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_0589  DNA-binding transcriptional activator CusR  45.58 
 
 
227 aa  209  3e-53  Escherichia coli E24377A  Bacteria  normal  0.180273  n/a   
 
 
-
 
NC_012892  B21_00521  hypothetical protein  45.58 
 
 
227 aa  209  3e-53  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  46.09 
 
 
225 aa  208  5e-53  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_008554  Sfum_2007  two component transcriptional regulator  49.12 
 
 
223 aa  208  5e-53  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  46.05 
 
 
225 aa  208  7e-53  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  46.7 
 
 
225 aa  207  8e-53  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  46.9 
 
 
223 aa  207  2e-52  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  47.11 
 
 
225 aa  206  3e-52  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_013132  Cpin_1247  two component transcriptional regulator, winged helix family  46.35 
 
 
235 aa  206  3e-52  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.464606  normal 
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  47.11 
 
 
225 aa  205  6e-52  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  47.11 
 
 
225 aa  205  6e-52  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  50 
 
 
228 aa  205  6e-52  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  47.11 
 
 
225 aa  205  6e-52  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_009438  Sputcn32_0258  DNA-binding transcriptional activator CusR  45.58 
 
 
226 aa  204  8e-52  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  45.61 
 
 
225 aa  204  8e-52  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  46.05 
 
 
225 aa  204  8e-52  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_008573  Shewana3_4296  DNA-binding transcriptional activator CusR  45.58 
 
 
226 aa  204  1e-51  Shewanella sp. ANA-3  Bacteria  decreased coverage  0.0000252174  normal 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  49.56 
 
 
226 aa  203  2e-51  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  48.02 
 
 
226 aa  202  3e-51  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_010501  PputW619_5178  two component heavy metal response transcriptional regulator  46.67 
 
 
225 aa  202  3e-51  Pseudomonas putida W619  Bacteria  normal  0.341313  normal 
 
 
-
 
NC_008463  PA14_45880  putative two-component response regulator  46.02 
 
 
229 aa  202  4e-51  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal  0.954426 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  44.49 
 
 
223 aa  201  5e-51  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  48.02 
 
 
226 aa  201  6e-51  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  48.02 
 
 
226 aa  201  7e-51  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  46.46 
 
 
231 aa  201  8e-51  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_3673  response regulator receiver  45.18 
 
 
227 aa  201  8e-51  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  46.05 
 
 
224 aa  201  9e-51  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  46.05 
 
 
224 aa  200  9.999999999999999e-51  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  45.13 
 
 
225 aa  200  1.9999999999999998e-50  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  44.69 
 
 
228 aa  199  1.9999999999999998e-50  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_007575  Suden_0317  two component transcriptional regulator  43.86 
 
 
224 aa  199  1.9999999999999998e-50  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_009656  PSPA7_3892  putative two-component response regulator  46.46 
 
 
229 aa  199  1.9999999999999998e-50  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_2957  two component transcriptional regulator  45.37 
 
 
223 aa  200  1.9999999999999998e-50  Pelobacter propionicus DSM 2379  Bacteria  unclonable  0.000000000406961  n/a   
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  44.69 
 
 
228 aa  199  1.9999999999999998e-50  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_008740  Maqu_3740  two component transcriptional regulator  43.61 
 
 
226 aa  199  1.9999999999999998e-50  Marinobacter aquaeolei VT8  Bacteria  normal  0.487084  n/a   
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  44.74 
 
 
225 aa  199  3e-50  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  44.69 
 
 
228 aa  199  3.9999999999999996e-50  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  46.26 
 
 
223 aa  199  3.9999999999999996e-50  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_011729  PCC7424_4284  two component transcriptional regulator, winged helix family  45.61 
 
 
227 aa  198  5e-50  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_010468  EcolC_3426  DNA-binding transcriptional activator CusR  44.69 
 
 
226 aa  198  5e-50  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  46.26 
 
 
223 aa  198  5e-50  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_009483  Gura_4293  two component transcriptional regulator  46.05 
 
 
224 aa  198  5e-50  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.0000000000934276  n/a   
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  46.26 
 
 
223 aa  198  5e-50  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_011667  Tmz1t_2388  heavy metal response regulator  44.93 
 
 
228 aa  198  6e-50  Thauera sp. MZ1T  Bacteria  decreased coverage  0.000142984  normal  0.119734 
 
 
-
 
NC_010002  Daci_1091  two component heavy metal response transcriptional regulator  44.49 
 
 
232 aa  198  6e-50  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_2101  two component heavy metal response transcriptional regulator, winged helix family  44.93 
 
 
228 aa  198  6e-50  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_009565  TBFG_10999  two component response transcriptional regulatory protein MprA  44.49 
 
 
230 aa  198  7e-50  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.00000000188235  normal  0.671639 
 
 
-
 
NC_010501  PputW619_1675  two component heavy metal response transcriptional regulator  48.9 
 
 
226 aa  197  1.0000000000000001e-49  Pseudomonas putida W619  Bacteria  normal  0.294903  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  46.9 
 
 
226 aa  197  1.0000000000000001e-49  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_1127  heavy metal response regulator  47.35 
 
 
225 aa  197  2.0000000000000003e-49  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.294376  normal  0.216529 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  43.81 
 
 
228 aa  196  2.0000000000000003e-49  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  43.11 
 
 
230 aa  197  2.0000000000000003e-49  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_014158  Tpau_3286  two component transcriptional regulator, winged helix family  44.05 
 
 
228 aa  196  3e-49  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.167791  n/a   
 
 
-
 
NC_002947  PP_1438  DNA-binding response regulator CzrR  46.9 
 
 
224 aa  196  3e-49  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  45.81 
 
 
225 aa  196  3e-49  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_009512  Pput_4283  two component heavy metal response transcriptional regulator  46.9 
 
 
224 aa  196  3e-49  Pseudomonas putida F1  Bacteria  normal  0.0230752  normal 
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  46.26 
 
 
223 aa  196  3e-49  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_008825  Mpe_A1629  two-component response regulator  43.61 
 
 
228 aa  196  3e-49  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.128663 
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  45.81 
 
 
223 aa  196  3e-49  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  46.9 
 
 
225 aa  196  4.0000000000000005e-49  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  43.36 
 
 
228 aa  195  4.0000000000000005e-49  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_010322  PputGB1_0836  two component heavy metal response transcriptional regulator  45.13 
 
 
224 aa  195  4.0000000000000005e-49  Pseudomonas putida GB-1  Bacteria  normal  0.368612  normal 
 
 
-
 
NC_010501  PputW619_4391  two component heavy metal response transcriptional regulator  45.13 
 
 
224 aa  195  4.0000000000000005e-49  Pseudomonas putida W619  Bacteria  normal  normal  0.593256 
 
 
-
 
NC_004578  PSPTO_0378  DNA-binding heavy metal response regulator  46.46 
 
 
224 aa  195  5.000000000000001e-49  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_004578  PSPTO_1307  DNA-binding heavy metal response regulator  46.46 
 
 
225 aa  195  5.000000000000001e-49  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.150056  n/a   
 
 
-
 
NC_007005  Psyr_1497  heavy metal response regulator  45.18 
 
 
228 aa  194  7e-49  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_007005  Psyr_4800  heavy metal response regulator  46.46 
 
 
224 aa  194  7e-49  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  hitchhiker  0.00185939 
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  43.05 
 
 
219 aa  194  7e-49  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_1026  two component transcriptional regulator  41.15 
 
 
224 aa  194  9e-49  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.000442073 
 
 
-
 
NC_009656  PSPA7_2714  putative two-component response regulator  46.46 
 
 
224 aa  194  1e-48  Pseudomonas aeruginosa PA7  Bacteria  normal  0.681326  n/a   
 
 
-
 
NC_008009  Acid345_1658  two component transcriptional regulator  46.93 
 
 
230 aa  194  1e-48  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.450735  normal 
 
 
-
 
NC_008463  PA14_31960  putative two-component response regulator  46.46 
 
 
224 aa  194  1e-48  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.029957  normal 
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  45.58 
 
 
226 aa  193  2e-48  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  46.9 
 
 
226 aa  193  2e-48  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  44.49 
 
 
229 aa  192  3e-48  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
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